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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | decreases expression | ISO | RGD:1319734 | 6480464 | Demecolcine results in decreased expression of FBXO5 mRNA | CTD | PMID:23649840 | 17beta-estradiol | increases expression | ISO | RGD:1319734 | 6480464 | Estradiol results in increased expression of FBXO5 mRNA | CTD | PMID:16474171, PMID:19167446 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:1319735 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:1319735 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1319734 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FBXO5 mRNA | CTD | PMID:21802500 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1319734 | 6480464 | Tetrachlorodibenzodioxin affects the expression of FBXO5 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1319735 | 6480464 | Tetrachlorodibenzodioxin affects the expression of FBXO5 mRNA | CTD | PMID:21570461 | 2-methylcholine | affects expression | ISO | RGD:1319734 | 6480464 | beta-methylcholine affects the expression of FBXO5 mRNA | CTD | PMID:21179406 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:1319735 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of FBXO5 mRNA | CTD | PMID:20188158 | 4-hydroxynon-2-enal | decreases expression | ISO | RGD:1319735 | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of FBXO5 mRNA | CTD | PMID:19191707 | 4-hydroxynon-2-enal | increases expression | ISO | RGD:1319735 | 6480464 | 4-hydroxy-2-nonenal results in increased expression of FBXO5 mRNA | CTD | PMID:19191707 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1319735 | 6480464 | Fenretinide results in increased expression of FBXO5 mRNA | CTD | PMID:28973697 | 5-fluorouracil | decreases expression | ISO | RGD:1319734 | 6480464 | Fluorouracil results in decreased expression of FBXO5 mRNA | CTD | PMID:16557594 | 5-fluorouracil | decreases expression | ISO | RGD:1319735 | 6480464 | Fluorouracil results in decreased expression of FBXO5 mRNA | CTD | PMID:19272435 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of FBXO5 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of FBXO5 mRNA | CTD | PMID:31881176 | aflatoxin B1 | affects expression | ISO | RGD:1319734 | 6480464 | Aflatoxin B1 affects the expression of FBXO5 protein | CTD | PMID:20106945 | aflatoxin B1 | increases expression | ISO | RGD:1319734 | 6480464 | Aflatoxin B1 results in increased expression of FBXO5 mRNA | CTD | PMID:27153756 | aflatoxin B1 | decreases methylation | ISO | RGD:1319734 | 6480464 | Aflatoxin B1 results in decreased methylation of FBXO5 gene | CTD | PMID:27153756 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of FBXO5 mRNA | CTD | PMID:23630614 | aflatoxin B1 | increases expression | ISO | RGD:1319735 | 6480464 | Aflatoxin B1 results in increased expression of FBXO5 mRNA | CTD | PMID:19770486 | antirheumatic drug | decreases expression | ISO | RGD:1319734 | 6480464 | Antirheumatic Agents results in decreased expression of FBXO5 mRNA | CTD | PMID:24449571 | azathioprine | decreases expression | ISO | RGD:1319734 | 6480464 | Azathioprine results in decreased expression of FBXO5 mRNA | CTD | PMID:22623647 | benzo[a]pyrene | decreases expression | ISO | RGD:1319734 | 6480464 | Benzoapyrene results in decreased expression of FBXO5 mRNA | CTD | PMID:21632981 more ... | benzo[a]pyrene | increases expression | ISO | RGD:1319734 | 6480464 | Benzoapyrene results in increased expression of FBXO5 mRNA | CTD | PMID:32234424 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1319734 | 6480464 | 7 more ... | CTD | PMID:20382639 | benzo[b]fluoranthene | increases expression | ISO | RGD:1319735 | 6480464 | benzobfluoranthene results in increased expression of FBXO5 mRNA | CTD | PMID:26377693 | bis(2-chloroethyl) sulfide | decreases expression | ISO | RGD:1319734 | 6480464 | Mustard Gas results in decreased expression of FBXO5 mRNA | CTD | PMID:25102026 | bisphenol A | increases expression | ISO | RGD:1319734 | 6480464 | bisphenol A results in increased expression of FBXO5 mRNA | CTD | PMID:16474171 | bisphenol A | decreases expression | ISO | RGD:1319734 | 6480464 | bisphenol A results in decreased expression of FBXO5 mRNA | CTD | PMID:29275510 | bisphenol A | affects expression | ISO | RGD:1319734 | 6480464 | bisphenol A affects the expression of FBXO5 mRNA | CTD | PMID:30903817 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of FBXO5 gene | CTD | PMID:28505145 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FBXO5 mRNA | CTD | PMID:25181051 | cadmium atom | decreases expression | ISO | RGD:1319734 | 6480464 | Cadmium results in decreased expression of FBXO5 mRNA | CTD | PMID:21120746 | calcitriol | decreases expression | ISO | RGD:1319734 | 6480464 | Calcitriol results in decreased expression of FBXO5 mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | RGD:1319734 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of FBXO5 mRNA | CTD | PMID:21592394 | captan | decreases expression | ISO | RGD:1319735 | 6480464 | Captan results in decreased expression of FBXO5 mRNA | CTD | PMID:31558096 | carbamazepine | affects expression | ISO | RGD:1319734 | 6480464 | Carbamazepine affects the expression of FBXO5 mRNA | CTD | PMID:25979313 | carbon nanotube | affects expression | ISO | RGD:1319735 | 6480464 | Nanotubes, Carbon affects the expression of FBXO5 mRNA | CTD | PMID:25554681 | carbon nanotube | increases expression | ISO | RGD:1319735 | 6480464 | Nanotubes, Carbon analog results in increased expression of FBXO5 mRNA | CTD | PMID:25554681 | cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of FBXO5 mRNA | CTD | PMID:18500788 | chromium(6+) | multiple interactions | ISO | RGD:1319734 | 6480464 | [Nocodazole co-treated with chromium hexavalent ion] results in decreased expression of FBXO5 protein | CTD | PMID:21670593 | cisplatin | increases expression | ISO | RGD:1319734 | 6480464 | Cisplatin results in increased expression of FBXO5 mRNA | CTD | PMID:27594783 | cisplatin | multiple interactions | ISO | RGD:1319734 | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of FBXO5 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | ISO | RGD:1319734 | 6480464 | cobaltous chloride results in decreased expression of FBXO5 mRNA | CTD | PMID:19320972 | copper atom | multiple interactions | ISO | RGD:1319734 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of FBXO5 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | RGD:1319734 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of FBXO5 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | RGD:1319734 | 6480464 | Copper Sulfate results in decreased expression of FBXO5 mRNA | CTD | PMID:19549813 | coumestrol | multiple interactions | ISO | RGD:1319734 | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | coumestrol | increases expression | ISO | RGD:1319734 | 6480464 | Coumestrol results in increased expression of FBXO5 mRNA | CTD | PMID:19167446 | crotonaldehyde | decreases expression | ISO | RGD:1319734 | 6480464 | 2-butenal results in decreased expression of FBXO5 mRNA | CTD | PMID:20471460 | CU-O LINKAGE | decreases expression | ISO | RGD:1319734 | 6480464 | cupric oxide results in decreased expression of FBXO5 mRNA | CTD | PMID:22077320 | cyclosporin A | affects expression | ISO | RGD:1319734 | 6480464 | Cyclosporine affects the expression of FBXO5 mRNA | CTD | PMID:20106945 | cyclosporin A | increases expression | ISO | RGD:1319734 | 6480464 | Cyclosporine results in increased expression of FBXO5 mRNA | CTD | PMID:27989131 | cyclosporin A | decreases expression | ISO | RGD:1319734 | 6480464 | Cyclosporine results in decreased expression of FBXO5 mRNA | CTD | PMID:21632981, PMID:25562108 | diazinon | increases methylation | ISO | RGD:1319734 | 6480464 | Diazinon results in increased methylation of FBXO5 gene | CTD | PMID:22964155 | dibenz[a,h]anthracene | increases expression | ISO | RGD:1319735 | 6480464 | 1 more ... | CTD | PMID:26377693 | dibutyl phthalate | decreases expression | ISO | RGD:1319735 | 6480464 | Dibutyl Phthalate results in decreased expression of FBXO5 mRNA | CTD | PMID:17361019, PMID:21266533 | disodium selenite | decreases expression | ISO | RGD:1319734 | 6480464 | Sodium Selenite results in decreased expression of FBXO5 mRNA | CTD | PMID:24383545 | dorsomorphin | multiple interactions | ISO | RGD:1319734 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | RGD:1319734 | 6480464 | Doxorubicin results in decreased expression of FBXO5 mRNA | CTD | PMID:29803840 | Enterolactone | multiple interactions | ISO | RGD:1319734 | 6480464 | [Coumestrol co-treated with 2, 3-bis3'-hydroxybenzylbutyrolactone] results in increased expression of FBXO5 mRNA | CTD | PMID:19167446 | folpet | decreases expression | ISO | RGD:1319735 | 6480464 | folpet results in decreased expression of FBXO5 mRNA | CTD | PMID:31558096 | fulvestrant | multiple interactions | ISO | RGD:1319734 | 6480464 | [fulvestrant co-treated with Sirolimus] results in decreased expression of FBXO5 mRNA | CTD | PMID:19016759 | fulvestrant | decreases expression | ISO | RGD:1319734 | 6480464 | fulvestrant results in decreased expression of FBXO5 mRNA | CTD | PMID:19016759 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of FBXO5 gene | CTD | PMID:22079235 | genistein | increases expression | ISO | RGD:1319734 | 6480464 | Genistein results in increased expression of FBXO5 mRNA | CTD | PMID:16474171 | geraniol | decreases expression | ISO | RGD:1319734 | 6480464 | geraniol results in decreased expression of FBXO5 mRNA | CTD | PMID:27683099 | hydroquinone | decreases expression | ISO | RGD:1319734 | 6480464 | hydroquinone results in decreased expression of FBXO5 mRNA | CTD | PMID:23416264 | leflunomide | decreases expression | ISO | RGD:1319734 | 6480464 | leflunomide results in decreased expression of FBXO5 mRNA | CTD | PMID:28988120 | lucanthone | decreases expression | ISO | RGD:1319734 | 6480464 | Lucanthone results in decreased expression of FBXO5 mRNA | CTD | PMID:21148553 | methyl methanesulfonate | increases expression | ISO | RGD:1319734 | 6480464 | Methyl Methanesulfonate results in increased expression of FBXO5 mRNA | CTD | PMID:23649840 | N-methyl-4-phenylpyridinium | decreases expression | ISO | RGD:1319734 | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of FBXO5 mRNA | CTD | PMID:24810058 | N-methyl-N-nitrosourea | increases expression | ISO | RGD:1319735 | 6480464 | Methylnitrosourea results in increased expression of FBXO5 mRNA | CTD | PMID:25270620 | N-Nitrosopyrrolidine | decreases expression | ISO | RGD:1319734 | 6480464 | N-Nitrosopyrrolidine results in decreased expression of FBXO5 mRNA | CTD | PMID:32234424 | nickel atom | increases expression | ISO | RGD:1319734 | 6480464 | Nickel results in increased expression of FBXO5 mRNA | CTD | PMID:25583101 | nocodazole | multiple interactions | ISO | RGD:1319734 | 6480464 | [Nocodazole co-treated with chromium hexavalent ion] results in decreased expression of FBXO5 protein | CTD | PMID:21670593 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of FBXO5 mRNA | CTD | PMID:25729387 | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of FBXO5 mRNA | CTD | PMID:25729387 | paclitaxel | affects expression | ISO | RGD:1319734 | 6480464 | Paclitaxel affects the expression of FBXO5 protein | CTD | PMID:27769712 | palbociclib | decreases expression | ISO | RGD:1319734 | 6480464 | palbociclib results in decreased expression of FBXO5 mRNA | CTD | PMID:22869556 | paracetamol | increases expression | ISO | RGD:1319734 | 6480464 | Acetaminophen results in increased expression of FBXO5 mRNA | CTD | PMID:22230336 | PCB138 | multiple interactions | ISO | RGD:1319735 | 6480464 | [2 more ... | CTD | PMID:25510870 | phenobarbital | affects expression | ISO | RGD:1319735 | 6480464 | Phenobarbital affects the expression of FBXO5 mRNA | CTD | PMID:23091169 | phenylmercury acetate | decreases expression | ISO | RGD:1319734 | 6480464 | Phenylmercuric Acetate results in decreased expression of FBXO5 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:1319734 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in decreased expression of FBXO5 mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | ISO | RGD:1319735 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FBXO5 mRNA | CTD | PMID:19710929 | propanal | decreases expression | ISO | RGD:1319734 | 6480464 | propionaldehyde results in decreased expression of FBXO5 mRNA | CTD | PMID:26079696 | quercetin | decreases expression | ISO | RGD:1319734 | 6480464 | Quercetin results in decreased expression of FBXO5 mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | RGD:1319734 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of FBXO5 mRNA | CTD | PMID:19167446 | rotenone | decreases expression | ISO | RGD:1319734 | 6480464 | Rotenone results in decreased expression of FBXO5 mRNA | CTD | PMID:29955902 | SB 431542 | multiple interactions | ISO | RGD:1319734 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | RGD:1319734 | 6480464 | Silicon Dioxide results in decreased expression of FBXO5 mRNA | CTD | PMID:25351596 | silicon dioxide | increases expression | ISO | RGD:1319735 | 6480464 | Silicon Dioxide results in increased expression of FBXO5 mRNA | CTD | PMID:29341224 | silver atom | decreases expression | ISO | RGD:1319734 | 6480464 | Silver results in decreased expression of FBXO5 mRNA | CTD | PMID:26014281 | silver(0) | decreases expression | ISO | RGD:1319734 | 6480464 | Silver results in decreased expression of FBXO5 mRNA | CTD | PMID:26014281 | sirolimus | multiple interactions | ISO | RGD:1319734 | 6480464 | [fulvestrant co-treated with Sirolimus] results in decreased expression of FBXO5 mRNA | CTD | PMID:19016759 | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of FBXO5 mRNA | CTD | PMID:22110744 | sodium dichromate | decreases expression | ISO | RGD:1319735 | 6480464 | sodium bichromate results in decreased expression of FBXO5 mRNA | CTD | PMID:31558096 | sodium dodecyl sulfate | decreases expression | ISO | RGD:1319734 | 6480464 | Sodium Dodecyl Sulfate results in decreased expression of FBXO5 mRNA | CTD | PMID:31734321 | sunitinib | decreases expression | ISO | RGD:1319734 | 6480464 | Sunitinib results in decreased expression of FBXO5 mRNA | CTD | PMID:31533062 | testosterone | multiple interactions | ISO | RGD:1319734 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of FBXO5 mRNA | CTD | PMID:21592394 | testosterone | decreases expression | ISO | RGD:1319734 | 6480464 | Testosterone results in decreased expression of FBXO5 mRNA | CTD | PMID:21592394 | tetrachloromethane | increases expression | ISO | RGD:1319735 | 6480464 | Carbon Tetrachloride results in increased expression of FBXO5 mRNA | CTD | PMID:17484886, PMID:31919559 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of FBXO5 mRNA | CTD | PMID:23411599 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of FBXO5 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of FBXO5 mRNA | CTD | PMID:25729387 | trichostatin A | decreases expression | ISO | RGD:1319734 | 6480464 | trichostatin A results in decreased expression of FBXO5 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:1319734 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in decreased expression of FBXO5 mRNA | CTD | PMID:27188386 | trimellitic anhydride | increases expression | ISO | RGD:1319735 | 6480464 | trimellitic anhydride results in increased expression of FBXO5 mRNA | CTD | PMID:19042947 | tungsten | increases expression | ISO | RGD:1319735 | 6480464 | Tungsten results in increased expression of FBXO5 mRNA | CTD | PMID:30912803 | urethane | decreases expression | ISO | RGD:1319734 | 6480464 | Urethane results in decreased expression of FBXO5 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | RGD:1319735 | 6480464 | Valproic Acid results in decreased expression of FBXO5 mRNA | CTD | PMID:15799026 | valproic acid | decreases expression | ISO | RGD:1319734 | 6480464 | Valproic Acid results in decreased expression of FBXO5 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | ISO | RGD:1319734 | 6480464 | Valproic Acid affects the expression of FBXO5 mRNA | CTD | PMID:25979313 | vanadyl sulfate | decreases expression | ISO | RGD:1319734 | 6480464 | vanadyl sulfate results in decreased expression of FBXO5 mRNA | CTD | PMID:16330358 | vincristine | decreases expression | ISO | RGD:1319734 | 6480464 | Vincristine results in decreased expression of FBXO5 mRNA | CTD | PMID:23649840 | zaragozic acid A | decreases expression | EXP | | 6480464 | squalestatin 1 results in decreased expression of FBXO5 mRNA | CTD | PMID:27225895 | zaragozic acid A | decreases expression | ISO | RGD:1319735 | 6480464 | squalestatin 1 results in decreased expression of FBXO5 mRNA | CTD | PMID:27225895 | |