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Gene: Pou5f1 (POU class 5 homeobox 1) Rattus norvegicus
Symbol: Pou5f1
Name: POU class 5 homeobox 1
Description: Exhibits several functions, including DNA-binding transcription factor activity; protein domain specific binding activity; and transcription coactivator activity. Involved in regulation of transcription, DNA-templated and response to cytokine. Localizes to nucleus. Human ortholog(s) of this gene implicated in embryonal carcinoma and seminoma. Orthologous to several human genes including POU5F1 (POU class 5 homeobox 1); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; all-trans-retinoic acid; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: POU domain, class 5, transcription factor 1
Homo sapiens (human) : POU5F1 (POU class 5 homeobox 1)  HGNC  Alliance
Mus musculus (house mouse) : Pou5f1 (POU domain, class 5, transcription factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pou5f1 (POU class 5 homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : POU5F1 (POU class 5 homeobox 1)
Canis lupus familiaris (dog) : POU5F1 (POU class 5 homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pou5f1 (POU class 5 homeobox 1)
Sus scrofa (pig) : POU5F1 (POU class 5 homeobox 1)
Chlorocebus sabaeus (African green monkey) : POU5F1 (POU class 5 homeobox 1)
Heterocephalus glaber (naked mole-rat) : Pou5f1 (POU class 5 homeobox 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0203,747,231 - 3,751,994 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,747,221 - 3,751,994 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,833,973 - 5,838,736 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera20650,325 - 655,095 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Pou5f1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359491
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.