Abcg1 (ATP binding cassette subfamily G member 1)

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Gene: Abcg1 (ATP binding cassette subfamily G member 1) Rattus norvegicus

Analyze

Symbol:

Abcg1

Name:

ATP binding cassette subfamily G member 1

RGD ID:

620294

Description:

Predicted to enable several functions, including adenyl ribonucleotide binding activity; protein dimerization activity; and sterol transporter activity. Involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus and positive regulation of secretory granule organization. Predicted to be located in external side of plasma membrane; mitochondrion; and recycling endosome. Predicted to be active in plasma membrane. Orthologous to human ABCG1 (ATP binding cassette subfamily G member 1); INTERACTS WITH (S)-nicotine; 1,2-dimethylhydrazine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Abc8; ATP-binding cassette sub-family G member 1; ATP-binding cassette, sub-family G (WHITE), member 1; ATP-binding cassette, subfamily G (WHITE), member 1

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ABCG1 (ATP binding cassette subfamily G member 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Abcg1 (ATP binding cassette subfamily G member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Abcg1 (ATP binding cassette subfamily G member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ABCG1 (ATP binding cassette subfamily G member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ABCG1 (ATP binding cassette subfamily G member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Abcg1 (ATP binding cassette subfamily G member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ABCG1 (ATP binding cassette subfamily G member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ABCG1 (ATP binding cassette subfamily G member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Abcg1 (ATP binding cassette subfamily G member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ABCG1 (ATP binding cassette subfamily G member 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Abcg1 (ATP binding cassette subfamily G member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	abcg1 (ATP-binding cassette, sub-family G (WHITE), member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Atet	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG17646	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG31689	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG32091	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG4822	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG5853	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG9663	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	wht-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	wht-4	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	wht-5	Alliance	DIOPT (InParanoid\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	wht-7	Alliance	DIOPT (InParanoid\|OrthoInspector\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	9,126,687 - 9,182,948 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	9,126,687 - 9,182,948 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	9,822,332 - 9,878,177 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	20	9,183,506 - 9,239,357 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	20	9,658,037 - 9,713,910 (+)	NCBI	Rnor_WKY
Rnor_6.0	20	9,743,269 - 9,842,735 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	9,743,269 - 9,840,489 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	11,922,393 - 12,022,892 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	9,390,485 - 9,459,574 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	9,390,711 - 9,459,801 (+)	NCBI
Celera	20	10,652,719 - 10,708,365 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autoimmune polyendocrine syndrome type 1 (ISO)

cataract 9 multiple types (ISO)

Colorectal Neoplasms (ISO)

developmental and epileptic encephalopathy 30 (ISO)

end stage renal disease (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

homocystinuria (ISO)

leukocyte adhesion deficiency 1 (ISO)

Neurodevelopmental Disorders (ISO)

primary ciliary dyskinesia (ISO)

progressive myoclonus epilepsy (ISO)

Weight Gain (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(24S)-24-hydroxycholesterol (ISO)

(25R)-cholest-5-ene-3beta,26-diol (ISO)

(S)-nicotine (EXP,ISO)

1,2-dimethylhydrazine (EXP)

1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine (EXP)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-amino-2-deoxy-D-glucopyranose (EXP)

2-trans,6-trans,10-trans-geranylgeranyl diphosphate (ISO)

22-Hydroxycholesterol (ISO)

25-hydroxycholesterol (ISO)

26-hydroxycholesterol (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (EXP,ISO)

5-aza-2'-deoxycytidine (ISO)

8-Br-cAMP (ISO)

9-cis-retinoic acid (ISO)

acetamide (EXP)

afimoxifene (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

aldehydo-D-glucosamine (EXP)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

arachidonic acid (ISO)

Aroclor 1254 (ISO)

atrazine (EXP)

beauvericin (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[e]pyrene (ISO)

beta-D-glucosamine (EXP)

beta-hexachlorocyclohexane (ISO)

beta-naphthoflavone (EXP)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

cholesterol (ISO)

cholic acid (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clodronic acid (ISO)

clofibrate (ISO)

clofibric acid (EXP)

clothianidin (ISO)

clozapine (ISO)

copper atom (ISO)

copper(0) (ISO)

coumestrol (ISO)

curcumin (ISO)

cyclosporin A (EXP,ISO)

cypermethrin (ISO)

D-glucose (ISO)

decabromodiphenyl ether (EXP)

dextran sulfate (ISO)

diazinon (ISO)

dibutyl phthalate (EXP,ISO)

dioxygen (ISO)

disulfiram (ISO)

endosulfan (EXP)

enniatin (ISO)

Enterolactone (ISO)

entinostat (ISO)

ethanol (EXP,ISO)

fenofibrate (EXP)

fenvalerate (EXP)

flusilazole (EXP)

gamma-hexachlorocyclohexane (ISO)

gentamycin (EXP)

glucose (ISO)

graphene oxide (ISO)

GW 3965 (ISO)

Heptachlor epoxide (ISO)

hexadecanoic acid (ISO)

high-density lipoprotein cholesterol (ISO)

ibuprofen (ISO)

ifosfamide (ISO)

isotretinoin (EXP)

ketamine (EXP)

kuwanone G (ISO)

linoleic acid (ISO)

lipopolysaccharide (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methamphetamine (EXP)

methapyrilene (ISO)

Morroniside (ISO)

N-acetyl-L-cysteine (ISO)

N-nitrosodiethylamine (EXP)

N-nitrosodimethylamine (EXP)

nickel atom (ISO)

nickel dichloride (ISO)

nicotine (EXP,ISO)

nicotinic acid (EXP,ISO)

obeticholic acid (ISO)

ochratoxin A (ISO)

octadecanoic acid (ISO)

oleic acid (ISO)

oxycodone (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

pentachlorophenol (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (EXP,ISO)

perfluorooctanoic acid (EXP,ISO)

phenytoin (ISO)

pirinixic acid (ISO)

progesterone (EXP,ISO)

raloxifene (ISO)

resveratrol (ISO)

rifampicin (ISO)

rosuvastatin calcium (ISO)

rotenone (EXP)

scopolamine (EXP)

silicon dioxide (ISO)

simvastatin (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

succimer (ISO)

sunitinib (ISO)

tamoxifen (ISO)

tebuconazole (ISO)

telmisartan (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

triadimefon (ISO)

tributylstannane (ISO)

Tributyltin oxide (ISO)

trichostatin A (ISO)

triclosan (ISO)

triphenyl phosphate (ISO)

troglitazone (EXP)

valproic acid (ISO)

vecuronium bromide (ISO)

vinclozolin (EXP)

vincristine (ISO)

zinc atom (EXP,ISO)

zinc sulfate (EXP)

zinc(0) (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amyloid precursor protein catabolic process (ISO)

cellular response to high density lipoprotein particle stimulus (ISO)

cholesterol efflux (ISO)

cholesterol homeostasis (IBA,ISO)

cholesterol metabolic process (ISO)

cholesterol transport (ISO,TAS)

glycoprotein transport (ISO)

high-density lipoprotein particle remodeling (ISO)

intermembrane lipid transfer (IEA)

intracellular cholesterol transport (ISO)

lipid translocation (IEA)

low-density lipoprotein particle remodeling (ISO)

negative regulation of lipid storage (ISO)

phospholipid efflux (ISO)

phospholipid homeostasis (ISO)

positive regulation of amyloid-beta formation (ISO)

positive regulation of cholesterol biosynthetic process (ISO)

positive regulation of cholesterol efflux (ISO)

positive regulation of insulin secretion involved in cellular response to glucose stimulus (IMP)

positive regulation of protein secretion (ISO)

positive regulation of secretory granule organization (IMP)

regulation of cholesterol metabolic process (ISO)

response to lipid (ISO)

response to organic substance (ISO)

reverse cholesterol transport (ISO)

toxin transport (IEA)

transmembrane transport (IBA)

Cellular Component

endosome (ISO)

external side of plasma membrane (ISO)

mitochondrion (ISO)

plasma membrane (IBA)

plasma membrane (ISO)

recycling endosome (ISO)

Molecular Function

ABC-type sterol transporter activity (IBA,ISO)

ADP binding (ISO)

ATP binding (ISO)

ATP hydrolysis activity (IEA)

cholesterol transfer activity (ISO)

floppase activity (ISO)

phosphatidylcholine floppase activity (ISO)

protein binding (ISO)

protein heterodimerization activity (ISO)

protein homodimerization activity (ISO)

toxin transmembrane transporter activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells.	Hoekstra M, etal., J Biol Chem 2003 Jul 11;278(28):25448-53.
4.	Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP.	Hussain SS, etal., Mol Biol Cell. 2018 May 15;29(10):1238-1257. doi: 10.1091/mbc.E17-08-0519. Epub 2018 Mar 22.
5.	ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport.	Klucken J, etal., Proc Natl Acad Sci U S A 2000 Jan 18;97(2):817-22.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Role of ABCG1 and other ABCG family members in lipid metabolism.	Schmitz G, etal., J Lipid Res 2001 Oct;42(10):1513-20.

Additional References at PubMed

PMID:11500512	PMID:15210959	PMID:15319426	PMID:15994327	PMID:16556852	PMID:16702602	PMID:16780588	PMID:16870176	PMID:16941710	PMID:17241464	PMID:17293612	PMID:17408620
PMID:17657311	PMID:17916878	PMID:19878707	PMID:21040802	PMID:21481393	PMID:21520072	PMID:21957962	PMID:22042635	PMID:22871113	PMID:24576892	PMID:24719980	PMID:25305669
PMID:25462452	PMID:26707062	PMID:34256330

Genomics

Comparative Map Data

Abcg1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	20	9,126,687 - 9,182,948 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	9,126,687 - 9,182,948 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	9,822,332 - 9,878,177 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	20	9,183,506 - 9,239,357 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	20	9,658,037 - 9,713,910 (+)	NCBI	Rnor_WKY
Rnor_6.0	20	9,743,269 - 9,842,735 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	9,743,269 - 9,840,489 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	11,922,393 - 12,022,892 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	9,390,485 - 9,459,574 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	9,390,711 - 9,459,801 (+)	NCBI
Celera	20	10,652,719 - 10,708,365 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI

ABCG1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	42,199,689 - 42,297,244 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	21	42,199,689 - 42,297,244 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	21	43,619,799 - 43,717,354 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	42,492,868 - 42,590,423 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	21	42,549,262 - 42,590,421	NCBI
Celera	21	28,767,307 - 28,866,320 (+)	NCBI		Celera
Cytogenetic Map	21	q22.3	NCBI
HuRef	21	29,038,262 - 29,134,637 (+)	NCBI		HuRef
CHM1_1	21	43,180,637 - 43,277,563 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	21	40,589,747 - 40,686,722 (+)	NCBI		T2T-CHM13v2.0

Abcg1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	31,276,668 - 31,336,958 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	31,276,649 - 31,336,962 (+)	Ensembl		GRCm39 Ensembl
GRCm38	17	31,057,694 - 31,117,984 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	31,057,675 - 31,117,988 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	31,194,639 - 31,254,929 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	30,777,799 - 30,842,789 (+)	NCBI		MGSCv36	mm8
Celera	17	31,974,265 - 32,035,260 (+)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI

Abcg1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	39,410,262 - 39,459,383 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	39,410,262 - 39,459,383 (-)	NCBI	ChiLan1.0	ChiLan1.0

ABCG1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	21	41,856,585 - 41,941,031 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	21	41,839,115 - 41,933,050 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	21	28,534,697 - 28,619,590 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

ABCG1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	36,574,406 - 36,627,598 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	36,553,380 - 36,620,043 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	35,705,119 - 35,775,022 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	36,070,404 - 36,140,582 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	36,070,329 - 36,137,398 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	35,963,992 - 36,033,708 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	35,943,824 - 36,013,708 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	36,438,763 - 36,508,785 (+)	NCBI		UU_Cfam_GSD_1.0

Abcg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	35,789,248 - 35,844,939 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936500	1,620,641 - 1,678,607 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936500	1,620,763 - 1,678,561 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABCG1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	205,561,951 - 205,628,425 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	205,561,897 - 205,628,428 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	215,898,408 - 215,965,031 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABCG1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	86,098,818 - 86,176,101 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	86,099,414 - 86,179,949 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	13,960,459 - 14,143,791 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Abcg1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	28,104,744 - 28,188,704 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624745	28,137,140 - 28,188,670 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Abcg1
440 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	339
Count of miRNA genes:	197
Interacting mature miRNAs:	241
Transcripts:	ENSRNOT00000001533
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24159021	Rat
1600382	Edcs3	Endometrial carcinoma susceptibility QTL3	3.5	0.003	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	20	1	25159026	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	2892597	26381954	Rat
1300152	Bp195	Blood pressure QTL 195	3.46		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	3621649	9243559	Rat
1331772	Cdexp2	CD45RC expression in CD8 T cells QTL 2	5.7		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	20	3621649	10078919	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	3621656	14101050	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	4606607	17617956	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	4606607	17617956	Rat
70154	Insul2	Insulin level QTL 2	3.75		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	6691706	17489458	Rat
1581577	Pur15	Proteinuria QTL 15	4.38	0.0002	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	20	8042410	17617956	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8042410	29322208	Rat
631265	Iresp1	Immunoglobin response QTL1	8.3		blood anti-double stranded DNA antibody amount (VT:0004762)	serum anti-DNA antibody level (CMO:0001533)	20	9039719	13461775	Rat

Markers in Region

RH141020

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	9,182,753 - 9,182,936 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	9,840,295 - 9,840,477	NCBI	Rnor6.0
Rnor_5.0	20	12,020,452 - 12,020,634	UniSTS	Rnor5.0
RGSC_v3.4	20	9,459,380 - 9,459,562	UniSTS	RGSC3.4
Celera	20	10,708,171 - 10,708,353	UniSTS
RH 3.4 Map	20	119.3	UniSTS
Cytogenetic Map	20	p12	UniSTS

BE119023

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	9,138,477 - 9,138,638 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	9,796,553 - 9,796,713	NCBI	Rnor6.0
Rnor_6.0	20	9,755,105 - 9,755,265	NCBI	Rnor6.0
Rnor_5.0	20	11,976,710 - 11,976,870	UniSTS	Rnor5.0
Rnor_5.0	20	11,933,293 - 11,933,453	UniSTS	Rnor5.0
RGSC_v3.4	20	9,403,229 - 9,403,389	UniSTS	RGSC3.4
Celera	20	10,664,531 - 10,664,691	UniSTS
RH 3.4 Map	20	117.7	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	24	26	16	19	16			68	24	27	11
Low	1	19	31	25		25	8	10	6	11	14		8
Below cutoff								1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053502	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ303374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000001533 ⟹ ENSRNOP00000001533

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	9,126,687 - 9,182,948 (+)	Ensembl
Rnor_6.0 Ensembl	20	9,743,269 - 9,840,489 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000078031 ⟹ ENSRNOP00000074901

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	9,133,023 - 9,182,948 (+)	Ensembl
Rnor_6.0 Ensembl	20	9,791,171 - 9,839,038 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000083505 ⟹ ENSRNOP00000070267

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	9,126,687 - 9,151,422 (+)	Ensembl
Rnor_6.0 Ensembl	20	9,743,296 - 9,839,236 (+)	Ensembl

RefSeq Acc Id:

NM_053502 ⟹ NP_445954

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	20	9,126,687 - 9,182,948 (+)	NCBI
Rnor_6.0	20	9,743,269 - 9,840,489 (+)	NCBI
Rnor_5.0	20	11,922,393 - 12,022,892 (+)	NCBI
RGSC_v3.4	20	9,390,485 - 9,459,574 (+)	RGD
Celera	20	10,652,719 - 10,708,365 (+)	RGD

Sequence:

show sequence

CCTCGTTCCTGCAACCTCGTCCCCGCCGCCCGCAGCCTCGTCTCCGCCGCCGCCGCCGCCGCCG
CCGCCCCCGGGGCATGGCCTGTCTGATGGCCGCTTTCTCGGTCGGCACCGCCATGAATGCCAGC
AACTACTCGGCCGCAATGACGGAACCCAAGTCCGTGTGCGTGTCGGTGGACGAGGTCGTGTCCA
GCAACGTGGATGAGCTTGAGACAGATCTGCTTAATGGGCACCTGAAGAAGGTGGACAACAACTT
CACGGAGGCCCAGCGCTTTTCCTCCCTGCCGCGGAGGGCGGCCGTGAATATCGAATTCAAGGAC
CTTTCTTACTCCGTACCCGAGGGACCCTGGTGGAGGAAGAAAGGATACAAGACCCTTTTGAAAG
GGATCTCTGGGAAGTTCAACAGTGGAGAGCTGGTGGCCATCATGGGTCCTTCTGGAGCTGGGAA
GTCCACACTCATGAATATTCTGGCGGGATACAGGGAGACGGGCATGAAGGGGGCAGTCCTTATC
AATGGTATGCCCCGCGACCTGCGCTGCTTCCGGAAGGTCTCGTGCTACATCATGCAGGATGACA
TGCTGCTGCCTCACCTCACTGTCCAGGAGGCCATGATGGTGTCCGCGCATCTGAAGCTGCAAGA
GAGGGATGAAGGCAGACGGGAGATGGTCAAGGAGATCCTGACAGCACTGGGCTTGCTGCCCTGT
GCCAACACACGCACAGGGAGCCTCTCGGGTGGCCAGCGGAAGCGCCTGGCCATTGCACTAGAAC
TGGTCAACAACCCTCCTGTTATGTTCTTTGATGAGCCCACCAGTGGCCTGGACAGTGCCTCTTG
CTTCCAAGTGGTGTCCCTGATGAAAGGGCTGGCCCAGGGCGGCCGCTCCATCGTCTGCACCATC
CACCAACCCAGTGCCAAGCTCTTCGAGCTCTTTGACCAGCTTTATGTCCTAAGTCAAGGACAAT
GTGTCTACCGGGGAAAGGTCTCGAATCTCGTGCCGTACCTGAGGGATCTGGGTCTGAACTGCCC
TACCTACCACAACCCTGCAGACTTTGTCATGGAAGTGGCATCAGGGGAGTACGGTGATCAGAAC
AGCCGCCTGGTGAGGGCCGTTCGGGAGGGCATGTGTGACTCTGACTATAAGAGAGAACTCGGGG
GCGACGGAGACGTGAACCCGTTCCTCTGGCACCGGCCTGCTGAAGAGGACTCGGCCTCCATGGA
AGGTTGCCACAGCTTCTCGGCCAGCTGCCTCACCCAGTTCTGCATCCTCTTCAAGAGGACCTTC
CTTAGCATCATGCGGGACTCGGTACTGACACACCTGCGAATCACCTCACACATCGGGATCGGTC
TCCTCATTGGCCTCCTGTACCTTGGGATTGGGAACGAAGCCAAGAAGGTCCTGAGCAACTCCGG
CTTCCTGTTCTTCTCCATGCTGTTCCTCATGTTCGCCGCCCTCATGCCCACCGTTCTGACCTTT
CCCCTCGAGATGAGTGTCTTCCTCCGAGAGCACCTGAACTACTGGTACAGTCTGAAGGCCTACT
ACCTGGCCAAGACCATGGCTGATGTCCCCTTTCAGATCATGTTCCCCGTGGCCTACTGCAGCAT
CGTGTACTGGATGACATCACAGCCGTCGGACGCTGTGCGTTTTGTGCTGTTCGCTGCACTGGGC
ACCATGACCTCGTTGGTGGCCCAGTCCTTAGGCCTACTCATTGGAGCTGCGTCCACATCCCTGC
AGGTTGCGACGTTTGTGGGTCCCGTGACAGCCATCCCTGTCTTGCTCTTCTCCGGGTTCTTTGT
CAGCTTTGACACCATCCCAACCTACCTGCAGTGGATGTCCTACATCTCCTACGTCAGATACGGC
TTCGAGGGGGTCATCCTGTCCATCTATGGCTTGGACCGAGAGGACCTGCACTGCGACATCGCGG
AGACATGCCACTTCCAGAAGTCAGAGGCCATCCTGCGGGAGCTAGATGTGGAGAACGCGAAGCT
ATACCTGGATTTCATCGTCCTGGGCATCTTCTTCATCTCCCTGCGGCTCATCGCCTATTTTGTC
CTGAGATACAAAATCCGGGCTGAGAGGTAAAACACCTCCACACTGGCAGTGAGGCAAAGCAGAC
ATTGTGACCAAGGACACTGCTGGGAGGTAGCAGTGCACCTGCTCCTGGTGACAAAGACTCTCCC
AACCCAACCTGGAGGCCACGCAGGTCGATGATGACCAGTGTTGAGCGCCTCCGCCCGCCGGGTT
GGAACTGTTCATTTCCTTTTCTAACTAAGAAGATGTAGGGCGGTTGGGGTTTTTTGACATGTGG
GACTCAAAACACACCTGGCACAGAATGTCATCCTCTGCTCCAGCTGGGGACAGGAGCTTCCTCA
GTAGACTCCTCCAGGGGTCTAGGACACACTGGCCCTGGATGAGAGGAGTGTTGGCTGAGTTGGT
CCCCAGAGAGGTGGATGTCTTAGGGACTCCGCCTGACGACTGTCTTCTCTTAAGGTCTCAGCCT
TCTAAAGTTCCTCTCATTTCTGATGAAGTCACTTTCCGAGCCAAAGCCGATAAATTTCATTCAC
TTCGAGAGATTGTATCTTTTTAGCACTTCTTGAGGACTTATTCAGGGTAAAGATGTGTTTTGCT
TAGAAACGGAAGAGTCCAACATAGTCACCGAGTGGGGGCGCTCACAGGCAAAACCGGAGAAGAA
GGTCAAACGCAGGCTCCAGGTGAGGGAGACACCACACCAGCTGCGCTGGGCCAGCAGGGACTCA
ATGCAATGCAACACAATGCAGACAGTGCTGGGGGGAGGTTGGCAGGCTCCTTCCAGACTTCCTT
TCTCATGTGCTTCTTATTTTAAGCAAACTAGATGGGTTTAAAAACTCTTCCTGGTTTTCCGGCT
ACTTTTATTTTGACCAAGAAATCCTCTATCCACCCTGTCAATTTTTAAAAGACCATTTTCCCTT
TTNTTCATAAATCACATTAACTACCTCCACAGAGCCTGGGAAGCCGGCCTGGGGACACATGGGG
TGCATCCCTCAAACTTGGGGGGGGGCAATAGGGTGTCAAGGACGGGCAGGCCAGCTGAGTGGAA
GGGGAGGTGCCATGAATGTCCCCATTAAGAAAACGCAGCTGCTCACCTCTGCCAGAGTACCACC
ACCCTAGGATCAGTCTCCTACAAAAGTCTCTATTTTTGTGGGCAGGTCAGTTTAACCCCTGTGA
GCCTCAGTTTCCCCACCTGTAAGTAATTGCACTGGATCTTGTTTTGACCGGTCCTGAGATTCCT
CGGCTGTGGCCTTGACGCTTTCGTATCTTATCTGTAGAGAGAGCTAAGGGTCCGAATTTTCCTT
ACGGCATGGAACGTGCTTTGGAACTATTTAGAGATTCTTTTTATTTTTTACACTCCTAGGTCTT
TTTTTATAGAGAACACGATTGAAATGCGTATTACGATGTAATCTTCAGTTTGCTTGTTCTATAC
AAACATGGCCTTGCCTTCTAGACTCAGCTTTTAACCAGGGACACGATTCGCCTTTATAAAAAGT
CTTCATT

hide sequence

Protein Sequences


Protein RefSeqs	NP_445954	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAC21556	(Get FASTA)	NCBI Sequence Viewer
	EDL96995	(Get FASTA)	NCBI Sequence Viewer
	EDL96996	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_445954 ⟸ NM_053502

- UniProtKB:

G3V642 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MACLMAAFSVGTAMNASNYSAAMTEPKSVCVSVDEVVSSNVDELETDLLNGHLKKVDNNFTEAQ
RFSSLPRRAAVNIEFKDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLM
NILAGYRETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQERDEG
RREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVV
SLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHN
PADFVMEVASGEYGDQNSRLVRAVREGMCDSDYKRELGGDGDVNPFLWHRPAEEDSASMEGCHS
FSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFF
SMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWM
TSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDT
IPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAETCHFQKSEAILRELDVENAKLYLDF
IVLGIFFISLRLIAYFVLRYKIRAER

hide sequence

RefSeq Acc Id:

ENSRNOP00000074901 ⟸ ENSRNOT00000078031

RefSeq Acc Id:

ENSRNOP00000070267 ⟸ ENSRNOT00000083505

RefSeq Acc Id:

ENSRNOP00000001533 ⟸ ENSRNOT00000001533

Protein Domains

ABC transporter

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V642-F1-model_v2	AlphaFold	G3V642	1-666	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701469

Promoter ID:

EPDNEW_R11993

Type:

initiation region

Name:

Abcg1_1

Description:

ATP binding cassette subfamily G member 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	9,743,255 - 9,743,315	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620294	AgrOrtholog
BioCyc Gene	G2FUF-4329	BioCyc
Ensembl Genes	ENSRNOG00000001158	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000001533	ENTREZGENE
	ENSRNOP00000001533.3	UniProtKB/TrEMBL
	ENSRNOP00000070267.2	UniProtKB/TrEMBL
	ENSRNOP00000074901.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000001533	ENTREZGENE
	ENSRNOT00000001533.5	UniProtKB/TrEMBL
	ENSRNOT00000078031.2	UniProtKB/TrEMBL
	ENSRNOT00000083505.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	ABC_2_trans	UniProtKB/TrEMBL
	ABC_transporter-like	UniProtKB/TrEMBL
	ABC_transporter_CS	UniProtKB/TrEMBL
	ABCG_dom	UniProtKB/TrEMBL
	ATPase_AAA+_core	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Pigment_permease	UniProtKB/TrEMBL
KEGG Report	rno:85264	UniProtKB/TrEMBL
NCBI Gene	85264	ENTREZGENE
PANTHER	ABC TRANSPORTER G FAMILY MEMBER 28	UniProtKB/TrEMBL
	PTHR48041:SF90	UniProtKB/TrEMBL
Pfam	ABC2_membrane	UniProtKB/TrEMBL
	ABC2_membrane_7	UniProtKB/TrEMBL
	ABC_tran	UniProtKB/TrEMBL
PhenoGen	Abcg1	PhenoGen
PROSITE	ABC_TRANSPORTER_1	UniProtKB/TrEMBL
	ABC_TRANSPORTER_2	UniProtKB/TrEMBL
SMART	AAA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
TIGRFAMs	3a01204	UniProtKB/TrEMBL
UniProt	A0A0G2JXH0_RAT	UniProtKB/TrEMBL
	A0A0G2K987_RAT	UniProtKB/TrEMBL
	G3V642	ENTREZGENE, UniProtKB/TrEMBL
	Q9EPG9_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-09	Abcg1	ATP binding cassette subfamily G member 1	Abcg1	ATP-binding cassette, subfamily G (WHITE), member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-11-16	Abcg1	ATP-binding cassette, subfamily G (WHITE), member 1	Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	abundant in Kupffer and liver endothelial cells	632216
gene_product	belongs to the ABCG (White) subfamily of transporters	634620
gene_regulation	expression in liver parenchymal cells is induced by high cholesterol diet

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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