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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cannabinoid receptor agonist
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Accession:CHEBI:67072 term browser browse the term
Definition:An agonist that binds to and activates cannabinoid receptors.
Synonyms:related_synonym: cannabinoid receptor agonists
 xref: Wikipedia:Cannabinoid_receptor

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11-hydroxy-Delta(9)-tetrahydrocannabinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp1 fatty acid binding protein 1 multiple interactions ISO
EXP		 [FABP1 protein affects the transport of Dronabinol] which affects the abundance of 11-hydroxy-delta(9)-tetrahydrocannabinol
11-hydroxy-delta(9)-tetrahydrocannabinol affects the folding of and results in increased stability of FABP1 protein; 11-hydroxy-delta(9)-tetrahydrocannabinol inhibits the reaction [anandamide analog binds to FABP1 protein]
11-hydroxy-delta(9)-tetrahydrocannabinol inhibits the reaction [11-(dansylamino)undecanoic acid binds to FABP1 protein]		 CTD PMID:30232874 PMID:31110286 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954 		JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 multiple interactions EXP 11-hydroxy-delta(9)-tetrahydrocannabinol binds to and results in increased activity of TRPV2 protein CTD PMID:18550765 NCBI chr10:48,903,540...48,925,036
Ensembl chr10:48,903,540...48,925,030 		JBrowse link
2-arachidonoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd12 abhydrolase domain containing 12, lysophospholipase increases hydrolysis ISO ABHD12 protein results in increased hydrolysis of glyceryl 2-arachidonate CTD PMID:18096503 NCBI chr 3:146,630,298...146,690,375
Ensembl chr 3:146,630,299...146,690,375 		JBrowse link
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase increases hydrolysis ISO ABHD6 protein results in increased hydrolysis of glyceryl 2-arachidonate CTD PMID:18096503 NCBI chr15:18,647,903...18,695,133
Ensembl chr15:18,647,844...18,695,133 		JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions		 EXP glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA
Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA]		 CTD PMID:21863215 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO [[APOE protein affects the susceptibility to [Cholesterol, Dietary co-treated with Dietary Fats]] which affects the susceptibility to JZL 184] which affects the abundance of glyceryl 2-arachidonate CTD PMID:29813086 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057 		JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139 		JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein] CTD PMID:31024316 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134 		JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in increased expression of ATF4 mRNA
iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of ATF4 mRNA]		 CTD PMID:32357311 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO glyceryl 2-arachidonate results in increased expression of BTG2 mRNA CTD PMID:28095641 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO glyceryl 2-arachidonate results in increased expression of CCL2 protein CTD PMID:15115777 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO glyceryl 2-arachidonate results in increased expression of CCR1 mRNA CTD PMID:29813086 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201 		JBrowse link
G Cd36 CD36 molecule increases expression ISO glyceryl 2-arachidonate results in increased expression of CD36 mRNA CTD PMID:29813086 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis
multiple interactions		 ISO CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate
[CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid		 CTD PMID:21049984 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821 		JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis
multiple interactions		 ISO CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate
[CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid		 CTD PMID:21049984 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases expression		 ISO
EXP		 CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
glyceryl 2-arachidonate results in increased expression of CNR1 mRNA
[GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]]
Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of CNR1 mRNA]; Nitroglycerin affects the reaction [glyceryl 2-arachidonate affects the activity of CNR1 protein]		 CTD PMID:12657697 PMID:15899896 PMID:16775503 PMID:21863215 PMID:23894352 PMID:26209559 PMID:28095641 PMID:31024316 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
affects response to substance		 ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; [SR 144528 binds to and results in increased activity of CNR2 protein] inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; glyceryl 2-arachidonate binds to and results in increased activity of CNR2 protein; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]
CNR2 gene SNP affects the susceptibility to glyceryl 2-arachidonate		 CTD PMID:10617657 PMID:15115777 PMID:20124950 PMID:30102254 PMID:31024316 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions
increases expression		 ISO glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA] CTD PMID:23894352 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282 		JBrowse link
G Crh corticotropin releasing hormone increases abundance ISO CRH protein results in increased abundance of glyceryl 2-arachidonate CTD PMID:26821211 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
increases expression		 ISO CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 increases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA]		 CTD PMID:23894352 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]		 CTD PMID:23894352 PMID:28095641 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA; glyceryl 2-arachidonate results in increased expression of DDIT3 protein
iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 protein]		 CTD PMID:29441458 PMID:32357311 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation		 ISO GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein] CTD PMID:32357311 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041 		JBrowse link
G Esrrg estrogen-related receptor gamma increases abundance ISO ESRRG protein results in increased abundance of glyceryl 2-arachidonate CTD PMID:31912162 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436 		JBrowse link
G Fabp1 fatty acid binding protein 1 affects abundance
multiple interactions		 ISO FABP1 protein affects the abundance of glyceryl 2-arachidonate
FABP1 protein affects the reaction [Dronabinol results in increased abundance of glyceryl 2-arachidonate]; FABP1 protein affects the reaction [glyceryl 2-arachidonate results in increased abundance of anandamide]		 CTD PMID:29414765 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954 		JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO [FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate CTD PMID:20393458 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions EXP FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:12657697 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO glyceryl 2-arachidonate results in increased expression of HSPA5 mRNA CTD PMID:32357311 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO glyceryl 2-arachidonate results in increased expression of ICAM1 mRNA CTD PMID:29813086 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in decreased expression of IL1B mRNA
glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]		 CTD PMID:16364651 PMID:30611738 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]] CTD PMID:21511917 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions		 ISO glyceryl 2-arachidonate results in decreased expression of IL6 mRNA
glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]]		 CTD PMID:16364651 PMID:30611738 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein] CTD PMID:12657697 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:12657697 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO
EXP		 CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein
glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]		 CTD PMID:12657697 PMID:31917333 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO
EXP		 CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein
glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]		 CTD PMID:12657697 PMID:31917333 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mgll monoglyceride lipase multiple interactions
affects abundance
increases degradation
increases abundance
increases hydrolysis		 EXP
ISO		 [Chlorpyrifos results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate; JZL 184 inhibits the reaction [MGLL protein results in increased hydrolysis of glyceryl 2-arachidonate]
MGLL protein affects the abundance of glyceryl 2-arachidonate
MGLL protein results in increased degradation of glyceryl 2-arachidonate
[FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate; [JZL 184 results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate
MGLL gene mutant form results in increased abundance of glyceryl 2-arachidonate		 CTD PMID:18096503 PMID:20393458 PMID:21507991 PMID:23761300 PMID:25030704 PMID:26209559 PMID:26642910 PMID:30301768 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]] CTD PMID:30611738 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased cleavage of PARP1 protein] CTD PMID:29441458 PMID:32357311 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects localization
multiple interactions		 EXP glyceryl 2-arachidonate affects the localization of PPARA protein
[palmidrol co-treated with glyceryl 2-arachidonate] affects the localization of PPARA protein; [palmidrol co-treated with glyceryl 2-arachidonate] affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]; glyceryl 2-arachidonate affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]		 CTD PMID:31787870 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding
multiple interactions
increases expression		 ISO glyceryl 2-arachidonate metabolite binds to PPARG protein
glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]
T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite results in increased expression of PPARG mRNA]		 CTD PMID:21511917 PMID:26209559 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [Indomethacin results in decreased expression of PTGS1] which results in increased activity of glyceryl 2-arachidonate CTD PMID:17245358 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases metabolic processing
multiple interactions		 ISO PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
glyceryl 2-arachidonate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA]; Ibuprofen inhibits the reaction [PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate]		 CTD PMID:18297109 PMID:21511917 PMID:26209559 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions		 ISO
EXP		 glyceryl 2-arachidonate results in decreased expression of TNF mRNA
glyceryl 2-arachidonate inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]; glyceryl 2-arachidonate inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein]
glyceryl 2-arachidonate inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]		 CTD PMID:12509806 PMID:16364651 PMID:30611738 PMID:30769029 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
affects response to substance		 EXP
ISO		 glyceryl 2-arachidonate binds to and results in increased activity of TRPV1 protein
TRPV1 protein affects the susceptibility to glyceryl 2-arachidonate		 CTD PMID:18550765 PMID:21949157 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679 		JBrowse link
G Yy1 YY1 transcription factor increases expression ISO glyceryl 2-arachidonate results in increased expression of YY1 mRNA CTD PMID:28095641 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046 		JBrowse link
anandamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases export ISO ABCB1 protein results in increased export of anandamide CTD PMID:30102254 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
decreases expression		 ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA]; anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]; iodopravadoline inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA]
anandamide results in decreased expression of ABCG2 mRNA; anandamide results in decreased expression of ABCG2 protein		 CTD PMID:30610963 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621 		JBrowse link
G App amyloid beta precursor protein decreases response to substance
decreases metabolic processing
decreases abundance		 EXP
ISO		 anandamide results in decreased susceptibility to APP protein
APP protein results in decreased metabolism of anandamide
APP protein results in decreased abundance of anandamide		 CTD PMID:22233683 PMID:26976670 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO anandamide promotes the reaction [CNR1 protein affects the localization of ARRB2 protein] CTD PMID:31024316 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134 		JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions
decreases activity		 ISO AM 251 inhibits the reaction [anandamide results in decreased activity of BDKRB1 protein] CTD PMID:19022239 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions		 ISO anandamide results in increased cleavage of CASP3 protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [anandamide results in increased cleavage of CASP3 protein]		 CTD PMID:26513129 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Cd36 CD36 molecule increases expression ISO anandamide results in increased expression of CD36 mRNA; anandamide results in increased expression of CD36 protein CTD PMID:17360047 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide decreases expression ISO anandamide results in decreased expression of CGA mRNA CTD PMID:30610963 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367 		JBrowse link
G Cnr1 cannabinoid receptor 1 affects activity
increases response to substance
decreases expression
affects binding
increases activity
multiple interactions		 ISO
EXP		 anandamide affects the activity of CNR1 protein
CNR1 protein results in increased susceptibility to anandamide
anandamide results in decreased expression of CNR1 protein
anandamide binds to CNR1 protein
anandamide results in increased activity of CNR1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased activity of CNR1]; anandamide promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 affects the reaction [TRPV1 affects the susceptibility to anandamide]; Pertussis Toxin inhibits the reaction [anandamide results in increased activity of CNR1]; Rimonabant inhibits the reaction [anandamide results in increased activity of CNR1]
[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; rimonabant inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; SR 144528 inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]		 CTD PMID:10871313 PMID:11408034 PMID:11891798 PMID:12657697 PMID:14504685 PMID:15453094 PMID:17557913 PMID:19147270 PMID:29730318 PMID:31024316 PMID:31199905 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Cnr2 cannabinoid receptor 2 affects activity
affects binding
multiple interactions		 ISO
EXP		 anandamide affects the activity of CNR2 protein
anandamide binds to CNR2 protein
anandamide binds to and results in increased activity of CNR2 protein; CNR2 affects the reaction [TRPV1 affects the susceptibility to anandamide]		 CTD PMID:10617657 PMID:10688601 PMID:15453094 PMID:19147270 PMID:30102254 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
decreases phosphorylation		 ISO anandamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]
anandamide results in decreased phosphorylation of CREB1 protein		 CTD PMID:30610963 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435 		JBrowse link
G Crh corticotropin releasing hormone decreases abundance ISO CRH protein results in decreased abundance of anandamide CTD PMID:26821211 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO anandamide results in increased expression of DDIT3 mRNA; anandamide results in increased expression of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [anandamide results in increased expression of DDIT3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [anandamide results in increased expression of DDIT3 protein]		 CTD PMID:21949157 PMID:26513129 PMID:29441458 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions		 ISO anandamide results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [anandamide results in increased phosphorylation of EIF2S1 protein]		 CTD PMID:26513129 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041 		JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope decreases expression ISO anandamide results in decreased expression of ERVFRD-1 mRNA CTD PMID:30610963 NCBI chr12:25,161,130...25,168,182
Ensembl chr12:25,161,130...25,168,182 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
increases expression		 ISO anandamide promotes the reaction [IL1B protein results in increased expression of F3 protein]
anandamide results in increased expression of F3 protein		 CTD PMID:27556861 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G Faah fatty acid amide hydrolase increases degradation
multiple interactions
affects expression		 ISO
EXP		 FAAH results in increased degradation of anandamide
FAAH protein results in increased degradation of anandamide
[Chlorpyrifos results in decreased activity of FAAH protein] which results in increased abundance of anandamide; [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester results in decreased activity of FAAH protein] which results in increased abundance of anandamide; [Lipopolysaccharides results in decreased expression of FAAH protein] which results in increased abundance of anandamide; Nitroglycerin promotes the reaction [FAAH protein results in increased degradation of anandamide]
anandamide affects the expression of FAAH protein
[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide; [nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]; [PF 3845 results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide		 CTD PMID:11556820 PMID:16131814 PMID:16886060 PMID:19515121 PMID:20702753 PMID:23761300 PMID:26642910 PMID:29787777 PMID:31121907 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775 		JBrowse link
G Faahl fatty-acid amide hydrolase-like increases degradation
affects expression
multiple interactions		 ISO FAAH results in increased degradation of anandamide
anandamide affects the expression of FAAH protein
[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide; [nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]; [PF 3845 results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide		 CTD PMID:16131814 PMID:16886060 PMID:20702753 PMID:31121907 NCBI chr 5:134,330,204...134,349,400
Ensembl chr 5:134,331,929...134,348,995 		JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions
affects abundance
affects binding		 EXP
ISO		 11-hydroxy-delta(9)-tetrahydrocannabinol inhibits the reaction [anandamide analog binds to FABP1 protein]; Dronabinol inhibits the reaction [anandamide analog binds to FABP1 protein]
FABP1 protein affects the abundance of anandamide
FABP1 protein affects the reaction [Dronabinol results in increased abundance of anandamide]; FABP1 protein affects the reaction [glyceryl 2-arachidonate results in increased abundance of anandamide]		 CTD PMID:29414765 PMID:30232874 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP anandamide inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; capsazepine inhibits the reaction [anandamide results in increased expression of FOS protein]; resiniferatoxin inhibits the reaction [anandamide results in increased expression of FOS protein]
anandamide results in increased expression of FOS; anandamide results in increased expression of FOS protein		 CTD PMID:9748483 PMID:15601931 PMID:19515121 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Ifng interferon gamma multiple interactions ISO anandamide affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF]; anandamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B] CTD PMID:12813001 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO anandamide results in increased expression of IGF1 protein CTD PMID:17307377 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO [OMDM-1 cpd co-treated with anandamide] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]; anandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15748152 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO anandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]
anandamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B]; anandamide promotes the reaction [IL1B protein results in increased expression of F3 protein]		 CTD PMID:12813001 PMID:15748152 PMID:27556861 PMID:30611738 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]] CTD PMID:30611738 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Lep leptin decreases abundance
multiple interactions
decreases activity
decreases transport		 ISO LEP protein results in decreased abundance of anandamide
Dietary Fats inhibits the reaction [LEP protein results in decreased abundance of anandamide]
LEP protein results in decreased activity of anandamide
LEP protein results in decreased transport of anandamide		 CTD PMID:16154199 PMID:29967158 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein; U 0126 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein] CTD PMID:12657697 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein; U 0126 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:12657697 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO
EXP		 anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
anandamide results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; Hydrogen Peroxide promotes the reaction [anandamide results in increased phosphorylation of MAPK1 protein]; JTE 907 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Pertussis Toxin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]		 CTD PMID:12657697 PMID:19477951 PMID:21179406 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
anandamide results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; Hydrogen Peroxide promotes the reaction [anandamide results in increased phosphorylation of MAPK3 protein]; JTE 907 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]		 CTD PMID:12657697 PMID:19477951 PMID:21179406 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO anandamide results in increased expression of MMP1 mRNA CTD PMID:16330497 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO anandamide results in increased expression of MMP3 mRNA CTD PMID:16330497 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression		 ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of MMP9 mRNA] CTD PMID:16330497 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO anandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; anandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:11891798 PMID:15748152 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO anandamide results in increased cleavage of PARP1 protein CTD PMID:29441458 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO anandamide binds to and results in increased activity of PPARA protein CTD PMID:17906680 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
increases metabolic processing		 EXP
ISO		 [nimesulide results in decreased expression of PTGS2] which results in increased activity of anandamide
anandamide results in increased expression of PTGS2 mRNA; anandamide results in increased expression of PTGS2 protein
PTGS2 results in increased metabolism of anandamide
[nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]		 CTD PMID:16330497 PMID:17245358 PMID:20702753 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Selp selectin P multiple interactions
increases expression		 ISO anandamide inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY results in increased expression of SELP protein]
anandamide results in increased expression of SELP protein		 CTD PMID:27151562 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions		 ISO anandamide results in increased expression of TIMP1 mRNA
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of TIMP1 mRNA]		 CTD PMID:16330497 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases abundance		 EXP
ISO		 anandamide inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]
anandamide inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]
TNF protein results in increased abundance of anandamide
anandamide affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF]		 CTD PMID:12509806 PMID:12813001 PMID:20626112 PMID:30611738 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases response to substance
increases activity
affects response to substance
affects binding		 ISO
EXP		 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; capsazepine inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; CNR1 affects the reaction [TRPV1 affects the susceptibility to anandamide]; CNR2 affects the reaction [TRPV1 affects the susceptibility to anandamide]; Egtazic Acid inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; methyl arachidonylfluorophosphonate promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; N-(2-methyl-3-hydroxyphenyl)-5,8,11,14-eicosatetraenamide inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Nitroprusside promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Phenylmethylsulfonyl Fluoride promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]
TRPV1 protein results in increased susceptibility to anandamide
anandamide results in increased activity of TRPV1 protein
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; bisindolylmaleimide inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Eicosapentaenoic Acid inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [anandamide results in increased activity of TRPV1 protein]
anandamide binds to TRPV1 protein		 CTD PMID:11140687 PMID:11278420 PMID:14504685 PMID:15453094 PMID:15601931 PMID:15615864 PMID:17038422 PMID:17913835 PMID:18550765 PMID:21949157 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO anandamide results in decreased expression of and results in decreased secretion of VEGFA protein CTD PMID:15313899 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
cannabidiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of ABL2 mRNA CTD PMID:26504004 NCBI chr13:74,154,533...74,333,244
Ensembl chr13:74,154,835...74,333,244 		JBrowse link
G Actn1 actinin, alpha 1 affects methylation EXP Cannabidiol affects the methylation of ACTN1 gene CTD PMID:30521419 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555 		JBrowse link
G Adcy5 adenylate cyclase 5 increases expression ISO Cannabidiol results in increased expression of ADCY5 mRNA CTD PMID:33019509 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320 		JBrowse link
G Adcy9 adenylate cyclase 9 decreases expression ISO Cannabidiol results in decreased expression of ADCY9 mRNA CTD PMID:33019509 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600 		JBrowse link
G Agtrap angiotensin II receptor-associated protein increases expression ISO Cannabidiol results in increased expression of AGTRAP mRNA CTD PMID:30742662 NCBI chr 5:164,888,069...164,898,387
Ensembl chr 5:164,886,813...164,898,420 		JBrowse link
G Aicda activation-induced cytidine deaminase increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of AICDA mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of AICDA mRNA		 CTD PMID:30742662 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671 		JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 increases expression ISO Cannabidiol results in increased expression of AKR1B7 mRNA CTD PMID:21542829 NCBI chr 4:61,850,256...61,879,733
Ensembl chr 4:61,850,348...61,862,526 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
affects expression
multiple interactions
increases expression		 ISO Cannabidiol results in decreased phosphorylation of AKT1 protein
Cannabidiol affects the expression of AKT1 protein
tanespimycin affects the reaction [Cannabidiol affects the expression of AKT1 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of AKT1 protein]
Cannabidiol results in increased expression of AKT1 mRNA		 CTD PMID:26504004 PMID:28392768 PMID:33019509 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Angptl6 angiopoietin-like 6 increases expression ISO Cannabidiol results in increased expression of ANGPTL6 mRNA CTD PMID:21542829 NCBI chr 8:21,895,523...21,902,002
Ensembl chr 8:21,895,524...21,901,829 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 affects methylation EXP Cannabidiol affects the methylation of APC2 gene CTD PMID:30521419 NCBI chr 7:12,258,468...12,280,459
Ensembl chr 7:12,258,468...12,275,609 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Cannabidiol inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GABRA1 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GRIA2 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of SNAP25 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of DLG4 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [APP gene mutant form co-treated with PSEN1 gene mutant form]		 CTD PMID:21350020 PMID:27567873 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [Cannabidiol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA] CTD PMID:31054246 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245 		JBrowse link
G Aqp4 aquaporin 4 affects expression ISO Cannabidiol affects the expression of AQP4 mRNA CTD PMID:31054246 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996 		JBrowse link
G Aqp9 aquaporin 9 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of AQP9 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of AQP9 mRNA		 CTD PMID:21542829 PMID:30742662 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781 		JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A affects methylation EXP Cannabidiol affects the methylation of ARPC1A gene CTD PMID:30521419 NCBI chr12:11,272,609...11,294,084
Ensembl chr12:11,272,609...11,294,058 		JBrowse link
G Arrb2 arrestin, beta 2 affects methylation EXP Cannabidiol affects the methylation of ARRB2 gene CTD PMID:30521419 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134 		JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO Cannabidiol results in increased expression of ASB2 mRNA CTD PMID:27256343 NCBI chr 6:127,212,325...127,248,451
Ensembl chr 6:127,212,273...127,248,372 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions
increases expression		 ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of ASNS mRNA
Cannabidiol results in increased expression of ASNS mRNA		 CTD PMID:26504004 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163 		JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of ATF3 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of ATF3 mRNA
Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of ATF3 mRNA]		 CTD PMID:21542829 PMID:26504004 PMID:27256343 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Cannabidiol results in increased expression of ATF4 mRNA CTD PMID:21542829 PMID:33019509 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO Cannabidiol results in increased expression of ATF5 mRNA CTD PMID:21542829 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522 		JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG12 mRNA] CTD PMID:30074247 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG4B mRNA] CTD PMID:30074247 NCBI chr 9:100,888,457...100,920,123
Ensembl chr 9:100,888,501...100,918,637 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Cannabidiol results in increased expression of ATP2A3 mRNA CTD PMID:21542829 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433 		JBrowse link
G Avil advillin increases expression ISO Cannabidiol results in increased expression of AVIL mRNA CTD PMID:21542829 NCBI chr 7:70,292,565...70,310,588
Ensembl chr 7:70,292,565...70,310,588 		JBrowse link
G Axin2 axin 2 affects methylation EXP Cannabidiol affects the methylation of AXIN2 gene CTD PMID:30521419 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642 		JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Cannabidiol results in increased expression of AXL mRNA CTD PMID:30742662 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of BACH1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of BACH1 mRNA		 CTD PMID:30742662 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Cannabidiol inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:27430346 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Cannabidiol results in increased expression of BCL2L1 mRNA CTD PMID:33019509 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Cannabidiol results in increased expression of BDNF protein CTD PMID:19939866 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210 		JBrowse link
G Becn1 beclin 1 multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of BECN1 mRNA] CTD PMID:30074247 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Bmp6 bone morphogenetic protein 6 affects methylation EXP Cannabidiol affects the methylation of BMP6 gene CTD PMID:30521419 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820 		JBrowse link
G Bmp7 bone morphogenetic protein 7 affects methylation EXP Cannabidiol affects the methylation of BMP7 gene CTD PMID:30521419 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399 		JBrowse link
G Bsg basigin (Ok blood group) decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of BSG mRNA
[Dronabinol co-treated with Cannabidiol] results in decreased expression of BSG mRNA; Cannabidiol promotes the reaction [Dronabinol results in decreased expression of BSG mRNA]; carfilzomib promotes the reaction [[Dronabinol co-treated with Cannabidiol] results in decreased expression of BSG mRNA]; Dronabinol promotes the reaction [Cannabidiol results in decreased expression of BSG mRNA]		 CTD PMID:27769052 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753 		JBrowse link
G Btla B and T lymphocyte associated multiple interactions
increases expression		 ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of BTLA mRNA]
Cannabidiol results in increased expression of BTLA mRNA		 CTD PMID:27256343 NCBI chr11:60,523,692...60,547,234
Ensembl chr11:60,524,917...60,547,201 		JBrowse link
G C1qa complement C1q A chain decreases expression ISO Cannabidiol results in decreased expression of C1QA mRNA CTD PMID:21542829 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A affects methylation EXP Cannabidiol affects the methylation of CACNA1A gene CTD PMID:30521419 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G affects methylation EXP Cannabidiol affects the methylation of CACNA1G gene CTD PMID:30521419 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I affects methylation EXP Cannabidiol affects the methylation of CACNA1I gene CTD PMID:30521419 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects methylation EXP Cannabidiol affects the methylation of CACNA2D1 gene CTD PMID:30521419 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848 		JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 affects methylation EXP Cannabidiol affects the methylation of CACNA2D2 gene CTD PMID:30521419 NCBI chr 8:116,154,661...116,285,643
Ensembl chr 8:116,154,736...116,284,985 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression ISO Cannabidiol results in decreased expression of CAMK2B mRNA CTD PMID:33019509 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652 		JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO Cannabidiol results in increased expression of CARS mRNA CTD PMID:21542829 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage		 ISO
EXP		 [bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein; [Cannabidiol co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [Cannabidiol results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [Cannabidiol results in increased cleavage of CASP3 protein]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 mRNA]		 CTD PMID:27430346 PMID:32708634 PMID:32733202 PMID:33076330 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp4 caspase 4 increases expression ISO Cannabidiol results in increased expression of CASP4 mRNA CTD PMID:21542829 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652 		JBrowse link
G Casp8 caspase 8 decreases expression ISO Cannabidiol results in decreased expression of CASP8 mRNA CTD PMID:33019509 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Cat catalase decreases activity ISO Cannabidiol results in decreased activity of CAT protein CTD PMID:32752303 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of CCL2 mRNA
Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]		 CTD PMID:19910459 PMID:21542829 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CCL22 mRNA CTD PMID:30742662 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145 		JBrowse link
G Ccl6 C-C motif chemokine ligand 6 decreases expression ISO Cannabidiol results in decreased expression of CCL6 mRNA CTD PMID:21542829 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO Cannabidiol results in decreased expression of CCL7 mRNA CTD PMID:21542829 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of CCND1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CCND1 mRNA		 CTD PMID:21542829 PMID:30742662 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Cannabidiol results in decreased expression of CCNE1 mRNA CTD PMID:21542829 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980 		JBrowse link
G Ccne2 cyclin E2 decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of CCNE2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CCNE2 mRNA		 CTD PMID:21542829 PMID:30742662 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406 		JBrowse link
G Cd274 CD274 molecule increases expression ISO Cannabidiol results in increased expression of CD274 mRNA CTD PMID:21542829 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943 		JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CD69 mRNA] CTD PMID:27256343 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084 		JBrowse link
G Cdc25a cell division cycle 25A decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of CDC25A mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CDC25A mRNA		 CTD PMID:21542829 PMID:30742662 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519 		JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Cannabidiol results in decreased expression of CDC6 mRNA CTD PMID:21542829 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402 		JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA] CTD PMID:32049991 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects expression
multiple interactions		 ISO Cannabidiol affects the expression of CDK1 protein
tanespimycin affects the reaction [Cannabidiol affects the expression of CDK1 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of CDK1 protein]		 CTD PMID:26504004 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CDK5R1 mRNA] CTD PMID:27256343 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of CDKN1A mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CDKN1A mRNA		 CTD PMID:21542829 PMID:30742662 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
decreases expression		 ISO
EXP		 Cannabidiol results in increased expression of CDKN2A mRNA
Cannabidiol results in decreased expression of CDKN2A mRNA		 CTD PMID:21542829 PMID:32553926 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO Cannabidiol results in increased expression of CDKN2B mRNA CTD PMID:21542829 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CEBPB mRNA
Cannabidiol results in increased expression of CEBPB mRNA		 CTD PMID:30742662 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Cannabidiol results in increased expression of CFLAR mRNA CTD PMID:30742662 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of CHAC1 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of CHAC1 mRNA		 CTD PMID:21542829 PMID:26504004 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425 		JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 increases expression ISO Cannabidiol results in increased expression of CHD2 mRNA CTD PMID:21542829 NCBI chr 1:134,757,934...134,873,053
Ensembl chr 1:134,757,934...134,871,167 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of CHRNA2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CHRNA2 mRNA		 CTD PMID:30742662 NCBI chr15:42,808,897...42,825,179
Ensembl chr15:42,808,897...42,825,179 		JBrowse link
G Chst10 carbohydrate sulfotransferase 10 decreases expression ISO Cannabidiol results in decreased expression of CHST10 mRNA CTD PMID:21542829 NCBI chr 9:45,528,928...45,559,365
Ensembl chr 9:45,528,928...45,559,140 		JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression ISO Cannabidiol results in increased expression of CISH mRNA CTD PMID:30742662 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723 		JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO Cannabidiol results in increased expression of CLEC4E mRNA CTD PMID:21542829 NCBI chr 4:156,271,087...156,276,243
Ensembl chr 4:156,270,920...156,276,304 		JBrowse link
G Clock clock circadian regulator decreases expression ISO Cannabidiol results in decreased expression of CLOCK mRNA CTD PMID:33019509 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CMPK2 mRNA] CTD PMID:27256343 NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
affects response to substance		 ISO
EXP		 CNR1 polymorphism affects the susceptibility to [Dronabinol co-treated with Cannabidiol]; CNR1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]
Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]
[1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene co-treated with CNR1 protein] affects the susceptibility to Cannabidiol
CNR1 protein affects the susceptibility to Cannabidiol		 CTD PMID:20668920 PMID:30550613 PMID:31013550 PMID:31202911 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
affects expression		 ISO CNR2 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]
Cannabidiol affects the expression of CNR2 mRNA		 CTD PMID:20668920 PMID:32733202 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression ISO Cannabidiol results in increased expression of COL4A1 mRNA CTD PMID:21542829 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153 		JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression ISO Cannabidiol results in increased expression of COX6A2 mRNA CTD PMID:21542829 NCBI chr 1:199,624,037...199,626,255
Ensembl chr 1:199,624,037...199,624,783 		JBrowse link
G Cpd carboxypeptidase D multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CPD mRNA CTD PMID:30742662 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817 		JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 increases expression ISO Cannabidiol results in increased expression of CPEB1 mRNA CTD PMID:21542829 NCBI chr 1:143,171,457...143,278,485
Ensembl chr 1:143,171,264...143,278,485 		JBrowse link
G Crb1 crumbs cell polarity complex component 1 affects methylation EXP Cannabidiol affects the methylation of CRB1 gene CTD PMID:30521419 NCBI chr13:56,270,519...56,462,893
Ensembl chr13:56,270,781...56,462,834 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
decreases expression
multiple interactions		 ISO Cannabidiol results in increased phosphorylation of CREB1 protein
Cannabidiol results in decreased expression of CREB1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [Cannabidiol results in increased phosphorylation of CREB1 protein]		 CTD PMID:28601556 PMID:33019509 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435 		JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CREM mRNA] CTD PMID:27256343 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha affects methylation EXP Cannabidiol affects the methylation of CSF2RA gene CTD PMID:30521419 NCBI chr14:1,462,292...1,467,264
Ensembl chr14:1,462,358...1,467,264 		JBrowse link
G Csnk1e casein kinase 1, epsilon affects methylation EXP Cannabidiol affects the methylation of CSNK1E gene CTD PMID:30521419 NCBI chr 7:120,651,976...120,675,559
Ensembl chr 7:120,651,881...120,672,359 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CSRNP1 mRNA] CTD PMID:27256343 NCBI chr 8:128,659,883...128,673,339
Ensembl chr 8:128,659,868...128,672,284 		JBrowse link
G Cth cystathionine gamma-lyase multiple interactions
increases expression		 ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of CTH mRNA
Cannabidiol results in increased expression of CTH mRNA		 CTD PMID:26504004 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046 		JBrowse link
G Ctsg cathepsin G increases expression ISO Cannabidiol results in increased expression of CTSG mRNA CTD PMID:21542829 NCBI chr15:35,107,333...35,113,678
Ensembl chr15:35,111,091...35,113,678 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases expression ISO Cannabidiol results in decreased expression of CX3CR1 mRNA CTD PMID:21542829 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 protein]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 protein]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] CTD PMID:32244040 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO Cannabidiol results in decreased expression of CXCL14 mRNA CTD PMID:21542829 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCL9 mRNA] CTD PMID:27256343 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCR1 mRNA] CTD PMID:27256343 NCBI chr 9:81,466,430...81,469,299
Ensembl chr 9:81,466,332...81,469,274 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
increases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CXCR4 mRNA
[Dronabinol co-treated with Cannabidiol] results in decreased expression of CXCR4 mRNA; carfilzomib promotes the reaction [[Dronabinol co-treated with Cannabidiol] results in decreased expression of CXCR4 mRNA]
Cannabidiol results in increased expression of CXCR4 mRNA		 CTD PMID:27769052 PMID:30742662 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
multiple interactions		 ISO Cannabidiol results in decreased activity of CYP19A1 protein
Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA]		 CTD PMID:31953017 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Cannabidiol results in decreased activity of CYP1A1 protein CTD PMID:24667653 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Cannabidiol results in decreased activity of CYP1A2 protein CTD PMID:24667653 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity ISO Cannabidiol results in decreased activity of CYP2B10 CTD PMID:8043019 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity ISO Cannabidiol results in decreased activity of CYP2B6 protein CTD PMID:24667653 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO Cannabidiol results in decreased activity of CYP2C19 protein CTD PMID:24667653 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Cannabidiol results in decreased activity of CYP2D6 protein CTD PMID:24667653 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436 		JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 decreases activity ISO Cannabidiol results in decreased activity of CYP3A4 protein CTD PMID:24667653 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases activity ISO Cannabidiol results in decreased activity of CYP3A5 protein CTD PMID:24667653 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399 		JBrowse link
G Cyrib CYFIP related Rac1 interactor B decreases expression ISO Cannabidiol results in decreased expression of CYRIB mRNA CTD PMID:21542829 NCBI chr 7:104,514,566...104,641,875
Ensembl chr 7:104,516,391...104,556,419 		JBrowse link
G Cytip cytohesin 1 interacting protein decreases expression ISO Cannabidiol results in decreased expression of CYTIP mRNA CTD PMID:21542829 NCBI chr 3:44,150,494...44,225,723
Ensembl chr 3:44,150,992...44,177,689 		JBrowse link
G Dapk3 death-associated protein kinase 3 affects methylation EXP Cannabidiol affects the methylation of DAPK3 gene CTD PMID:30521419 NCBI chr 7:11,392,436...11,400,855
Ensembl chr 7:11,392,437...11,400,805 		JBrowse link
G Dct dopachrome tautomerase increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of DCT mRNA; Cannabidiol results in increased expression of DCT protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of DCT mRNA]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of DCT mRNA]		 CTD PMID:28601556 NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of DDIT3 mRNA
Cannabidiol results in increased expression of DDIT3 mRNA; Cannabidiol results in increased expression of DDIT3 protein
[Dronabinol co-treated with Cannabidiol] results in increased expression of DDIT3 mRNA
[Bilirubin co-treated with Rotenone] promotes the reaction [Cannabidiol results in increased expression of DDIT3 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of DDIT3 mRNA]; Rotenone promotes the reaction [Cannabidiol results in increased expression of DDIT3 mRNA]		 CTD PMID:21542829 PMID:26504004 PMID:29441458 PMID:32033040 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of DDIT4 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of DDIT4 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of DDIT4 mRNA		 CTD PMID:21542829 PMID:26504004 PMID:30742662 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression ISO Cannabidiol results in increased expression of DDR1 mRNA CTD PMID:27256343 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of DGAT1 mRNA] CTD PMID:27256343 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects methylation
multiple interactions		 EXP
ISO		 Cannabidiol affects the methylation of DLG4 gene
[Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of DLG4 protein]		 CTD PMID:27567873 PMID:30521419 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599 		JBrowse link
G Dlgap1 DLG associated protein 1 increases expression ISO Cannabidiol results in increased expression of DLGAP1 mRNA CTD PMID:33019509 NCBI chr 9:118,277,046...119,159,807
Ensembl chr 9:118,586,179...119,158,196 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions
increases expression		 ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of DLL1 mRNA]
Cannabidiol results in increased expression of DLL1 mRNA		 CTD PMID:30742662 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379 		JBrowse link
G Dmd dystrophin multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG12 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG4B mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of BECN1 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ULK1 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of IL6 protein]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of IL6RA mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of NOS2 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TGFB1 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TNF mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TNF protein] CTD PMID:30074247 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO Cannabidiol results in increased expression of DNAJB1 mRNA CTD PMID:26504004 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions
increases expression		 ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of DNAJB4 mRNA
Cannabidiol results in increased expression of DNAJB4 mRNA		 CTD PMID:26504004 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 multiple interactions
increases expression		 ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of DNAJB9 mRNA
Cannabidiol results in increased expression of DNAJB9 mRNA		 CTD PMID:26504004 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151 		JBrowse link
G Dnmt3l DNA methyltransferase 3 like increases expression ISO Cannabidiol results in increased expression of DNMT3L mRNA CTD PMID:21542829 NCBI chr20:11,344,513...11,359,090
Ensembl chr20:11,344,514...11,359,090 		JBrowse link
G Dok2 docking protein 2 decreases expression ISO Cannabidiol results in decreased expression of DOK2 mRNA CTD PMID:21542829 NCBI chr15:52,449,884...52,455,414
Ensembl chr15:52,451,161...52,456,409 		JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO Cannabidiol results in decreased expression of DRD2 mRNA CTD PMID:33019509 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Cannabidiol results in increased expression of DUSP1 mRNA CTD PMID:21542829 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO [Cannabidiol co-treated with MOG protein modified form] results in increased expression of DUSP6 mRNA; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of DUSP6 mRNA] CTD PMID:27256343 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392 		JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO Cannabidiol results in increased expression of E2F2 mRNA CTD PMID:30742662 NCBI chr 5:154,516,611...154,540,228
Ensembl chr 5:154,522,119...154,540,265 		JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO Cannabidiol results in decreased expression of E2F5 mRNA CTD PMID:30742662 NCBI chr 2:88,350,764...88,366,913
Ensembl chr 2:88,351,361...88,366,115 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in decreased expression of EGFR mRNA; Pertussis Toxin inhibits the reaction [[Dronabinol co-treated with Cannabidiol] results in decreased expression of EGFR mRNA] CTD PMID:32049991 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of EGR1 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of EGR1 mRNA		 CTD PMID:26504004 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 decreases expression ISO Cannabidiol results in decreased expression of EIF2AK3 mRNA CTD PMID:33019509 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO Cannabidiol results in increased expression of EIF4EBP1 mRNA CTD PMID:21542829 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression ISO Cannabidiol results in decreased expression of EIF5A mRNA CTD PMID:21542829 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483 		JBrowse link
G Eno2 enolase 2 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of ENO2 mRNA] CTD PMID:17672854 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO Cannabidiol results in increased expression of EPHX1 mRNA CTD PMID:27256343 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression ISO Cannabidiol results in decreased expression of ERN1 mRNA CTD PMID:33019509 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO Cannabidiol results in increased expression of ETS2 mRNA CTD PMID:27256343 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495 		JBrowse link
G Ezr ezrin affects methylation EXP Cannabidiol affects the methylation of EZR gene CTD PMID:30521419 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO Cannabidiol results in increased expression of F3 protein CTD PMID:27556861 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO Cannabidiol inhibits the reaction [11-(dansylamino)undecanoic acid binds to FABP1 protein] CTD PMID:31110286 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Cannabidiol results in increased expression of FAS mRNA CTD PMID:30742662 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Fbxo32 F-box protein 32 multiple interactions
increases expression		 ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of FBXO32 mRNA
Cannabidiol results in increased expression of FBXO32 mRNA		 CTD PMID:26504004 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268 		JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of FDPS mRNA] CTD PMID:27256343 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219 		JBrowse link
G Fgf12 fibroblast growth factor 12 affects methylation EXP Cannabidiol affects the methylation of FGF12 gene CTD PMID:30521419 NCBI chr11:75,606,360...76,171,078
Ensembl chr11:75,905,443...76,168,989 		JBrowse link
G Fgf14 fibroblast growth factor 14 affects methylation EXP Cannabidiol affects the methylation of FGF14 gene CTD PMID:30521419 NCBI chr15:110,382,274...111,077,027
Ensembl chr15:110,385,217...110,612,681 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects methylation EXP Cannabidiol affects the methylation of FGFR2 gene CTD PMID:30521419 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 affects methylation EXP Cannabidiol affects the methylation of FGFR4 gene CTD PMID:30521419 NCBI chr17:9,990,072...10,004,339
Ensembl chr17:9,990,078...10,004,321 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of FOS mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of FOS mRNA		 CTD PMID:21542829 PMID:30742662 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Cannabidiol results in increased expression of FOSB mRNA CTD PMID:26504004 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA] CTD PMID:31953017 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016 		JBrowse link
G Fzd9 frizzled class receptor 9 affects methylation EXP Cannabidiol affects the methylation of FZD9 gene CTD PMID:30521419 NCBI chr12:24,473,981...24,476,295
Ensembl chr12:24,473,981...24,476,295 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GABRA1 protein] CTD PMID:27567873 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665 		JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions EXP Cannabidiol inhibits the reaction [Poly I-C results in decreased expression of GAD1 protein] CTD PMID:31202911 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of GADD45A mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of GADD45A mRNA		 CTD PMID:21542829 PMID:26504004 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842 		JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions
increases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of GAS1 mRNA
Cannabidiol results in increased expression of GAS1 mRNA		 CTD PMID:30742662 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Cannabidiol results in increased expression of GCLM mRNA CTD PMID:21542829 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of GDF15 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of GDF15 mRNA		 CTD PMID:21542829 PMID:26504004 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978 		JBrowse link
G Gdf6 growth differentiation factor 6 affects methylation EXP Cannabidiol affects the methylation of GDF6 gene CTD PMID:30521419 NCBI chr 5:23,056,345...23,072,666
Ensembl chr 5:23,056,347...23,074,599 		JBrowse link
G Gfod1 glucose-fructose oxidoreductase domain containing 1 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GFOD1 mRNA] CTD PMID:27256343 NCBI chr17:23,818,370...23,924,393
Ensembl chr17:23,823,632...23,923,792 		JBrowse link
G Gli1 GLI family zinc finger 1 affects methylation EXP Cannabidiol affects the methylation of GLI1 gene CTD PMID:30521419 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338 		JBrowse link
G Gnai2 G protein subunit alpha i2 increases expression ISO Cannabidiol results in increased expression of GNAI2 mRNA CTD PMID:33019509 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307 		JBrowse link
G Gnal G protein subunit alpha L decreases expression ISO Cannabidiol results in decreased expression of GNAL mRNA CTD PMID:33019509 NCBI chr18:62,805,406...62,946,133
Ensembl chr18:62,805,410...62,944,630 		JBrowse link
G Gnb2 G protein subunit beta 2 affects methylation EXP Cannabidiol affects the methylation of GNB2 gene CTD PMID:30521419 NCBI chr12:22,229,079...22,234,096
Ensembl chr12:22,229,079...22,234,096 		JBrowse link
G Gnb4 G protein subunit beta 4 increases expression ISO Cannabidiol results in increased expression of GNB4 mRNA CTD PMID:33019509 NCBI chr 2:118,978,965...119,007,877
Ensembl chr 2:118,978,973...119,007,835 		JBrowse link
G Gng7 G protein subunit gamma 7 affects methylation EXP Cannabidiol affects the methylation of GNG7 gene CTD PMID:30521419 NCBI chr 7:11,565,740...11,629,519
Ensembl chr 7:11,582,984...11,628,929 		JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Cannabidiol results in increased expression of GPNMB mRNA CTD PMID:27256343 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683 		JBrowse link
G Gpr183 G protein-coupled receptor 183 decreases expression ISO Cannabidiol results in decreased expression of GPR183 mRNA CTD PMID:21542829 NCBI chr15:108,364,701...108,376,221
Ensembl chr15:108,364,701...108,376,221 		JBrowse link
G Gpr83 G protein-coupled receptor 83 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of GPR83 mRNA] CTD PMID:27256343 NCBI chr 8:13,365,583...13,376,071
Ensembl chr 8:13,365,583...13,376,070 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Cannabidiol results in increased expression of GPT2 mRNA CTD PMID:21542829 NCBI chr19:22,599,003...22,633,529
Ensembl chr19:22,590,881...22,632,071 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GRIA2 protein] CTD PMID:27567873 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO Cannabidiol results in decreased activity of GSR protein CTD PMID:18929579 PMID:32752303 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO Cannabidiol results in increased expression of GSTM1 mRNA CTD PMID:21542829 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Cannabidiol results in increased expression of H1F2 mRNA CTD PMID:21542829 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression		 ISO Cannabidiol promotes the reaction [Dronabinol results in increased expression of H2AX protein modified form]; Dronabinol promotes the reaction [Cannabidiol results in increased expression of H2AX protein modified form] CTD PMID:27769052 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G Hap1 huntingtin-associated protein 1 increases expression ISO Cannabidiol results in increased expression of HAP1 mRNA CTD PMID:33019509 NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210 		JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO Cannabidiol results in increased expression of HBP1 mRNA CTD PMID:30742662 NCBI chr 6:51,231,479...51,257,699
Ensembl chr 6:51,231,480...51,257,625 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of HERPUD1 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of HERPUD1 mRNA		 CTD PMID:21542829 PMID:26504004 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254 		JBrowse link
G Hes2 hes family bHLH transcription factor 2 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of HES2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of HES2 mRNA		 CTD PMID:30742662 NCBI chr 5:169,338,097...169,339,142
Ensembl chr 5:169,338,097...169,339,142 		JBrowse link
G Hgf hepatocyte growth factor affects methylation EXP Cannabidiol affects the methylation of HGF gene CTD PMID:30521419 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hist1h2af histone cluster 1 H2A family member F increases expression ISO Cannabidiol results in increased expression of H2AC6 mRNA CTD PMID:21542829 NCBI chr17:43,627,237...43,627,629
Ensembl chr17:43,627,237...43,627,629 		JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 increases expression ISO Cannabidiol results in increased expression of H3C6 mRNA CTD PMID:21542829 NCBI chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183 		JBrowse link
G Hist2h2be histone cluster 2 H2B family member E increases expression ISO Cannabidiol results in increased expression of H2BC21 mRNA CTD PMID:21542829 NCBI chr 2:198,360,837...198,363,399
Ensembl chr 2:198,360,998...198,361,378 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
affects response to substance		 ISO Cannabidiol results in increased expression of HMOX1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of HMOX1 mRNA; [Rotenone co-treated with Bilirubin] inhibits the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]; Rotenone promotes the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]
Cannabidiol results in increased expression of HMOX1 mRNA; Cannabidiol results in increased expression of HMOX1 protein
HMOX1 protein affects the susceptibility to Cannabidiol
[bafilomycin A1 co-treated with tin protoporphyrin IX] promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; [Dronabinol co-treated with Cannabidiol] results in increased expression of HMOX1 mRNA; Acetylcysteine inhibits the reaction [Cannabidiol results in increased expression of HMOX1 protein]; iodopravadoline promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Cannabidiol results in increased expression of HMOX1 protein]; tin protoporphyrin IX promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]		 CTD PMID:21542829 PMID:26504004 PMID:30349652 PMID:30742662 PMID:32033040 PMID:32708634 PMID:33076330 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hnf1a HNF1 homeobox A affects methylation EXP Cannabidiol affects the methylation of HNF1A gene CTD PMID:30521419 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342 		JBrowse link
G Hp haptoglobin increases expression ISO Cannabidiol results in increased expression of HP mRNA CTD PMID:21542829 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Cannabidiol results in increased expression of HSPA1A mRNA CTD PMID:26504004 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of HSPA1B mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of HSPA1B mRNA		 CTD PMID:26504004 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Cannabidiol co-treated with Rotenone] results in increased expression of HSPA5 mRNA; Bilirubin inhibits the reaction [[Cannabidiol co-treated with Rotenone] results in increased expression of HSPA5 mRNA] CTD PMID:32033040 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Cannabidiol results in increased expression of HTATIP2 mRNA CTD PMID:21542829 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]; AM 251 inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]; capsazepine inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]; ICAM1 mutant form inhibits the reaction [Cannabidiol results in increased expression of TIMP1 protein]; iodopravadoline inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]
Cannabidiol results in increased expression of ICAM1 mRNA; Cannabidiol results in increased expression of ICAM1 protein		 CTD PMID:22198381 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression
affects response to substance		 ISO Cannabidiol results in decreased expression of ID1 mRNA; Cannabidiol results in decreased expression of ID1 protein
ID1 protein affects the susceptibility to Cannabidiol		 CTD PMID:21542829 PMID:24910342 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO AM 281 promotes the reaction [Cannabidiol inhibits the reaction [Plant Preparations results in increased activity of IDO1 protein]]; Cannabidiol inhibits the reaction [[Plant Preparations results in increased activity of IDO1 protein] which results in increased abundance of Neopterin]; Cannabidiol inhibits the reaction [Plant Preparations results in increased activity of IDO1 protein]; Cannabidiol inhibits the reaction [Plant Preparations results in increased expression of IDO1 mRNA]; iodopravadoline promotes the reaction [Cannabidiol inhibits the reaction [Plant Preparations results in increased activity of IDO1 protein]] CTD PMID:19167098 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098 		JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IER3 mRNA] CTD PMID:27256343 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions
increases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of IFNB1 mRNA; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNB1 mRNA]; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IFNB1 protein]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
Cannabidiol results in increased expression of IFNB1 mRNA		 CTD PMID:19910459 PMID:21542829 PMID:30742662 PMID:32244040 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Cannabidiol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [IFNG protein results in increased expression of PSMB8 protein]; Cannabidiol affects the reaction [Plant Preparations results in increased secretion of IFNG protein]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA]; Cannabidiol inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]; Cannabidiol inhibits the reaction [IFNG protein results in increased expression of PSMB8 protein]; Cannabidiol inhibits the reaction [Plant Preparations results in increased expression of IFNG mRNA]; Cannabidiol promotes the reaction [Dronabinol inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]]; Dronabinol promotes the reaction [Cannabidiol inhibits the reaction [IFNG results in increased expression of PSMB8 mRNA]] CTD PMID:19167098 PMID:27769052 PMID:31054246 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IFNGR1 mRNA] CTD PMID:27256343 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA] CTD PMID:31953017 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of IGFBP4 mRNA
Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IGFBP4 mRNA]		 CTD PMID:21542829 PMID:27256343 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL12A mRNA] CTD PMID:27256343 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression		 ISO
EXP		 Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL1B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL1B protein]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of IL1B protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
Cannabidiol results in decreased expression of IL1B mRNA		 CTD PMID:19910459 PMID:21492165 PMID:21542829 PMID:27256343 PMID:27430346 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il2 interleukin 2 increases expression ISO Cannabidiol results in increased expression of IL2 protein CTD PMID:11809870 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854 		JBrowse link
G Il3 interleukin 3 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL3 protein] CTD PMID:27256343 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO
EXP		 [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of IL6 mRNA; [Rotenone co-treated with Bilirubin] inhibits the reaction [Cannabidiol results in increased expression of IL6 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of IL6 mRNA]; Cannabidiol inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of IL6 protein]; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]; Rotenone inhibits the reaction [Cannabidiol results in increased expression of IL6 mRNA]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]		 CTD PMID:19910459 PMID:21350020 PMID:21492165 PMID:27430346 PMID:30074247 PMID:30742662 PMID:32033040 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Il6r interleukin 6 receptor decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of IL6RA mRNA
Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of IL6RA mRNA]		 CTD PMID:30074247 PMID:30742662 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D decreases expression ISO Cannabidiol results in decreased expression of INPP5D mRNA CTD PMID:30742662 NCBI chr 9:94,745,220...94,850,778
Ensembl chr 9:94,745,217...94,850,771 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of IRAK1 protein] CTD PMID:19910459 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of IRAK3 mRNA CTD PMID:30742662 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281 		JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C affects the localization of IRF3 protein]; Cannabidiol inhibits the reaction [Poly I-C affects the localization of IRF3 protein] CTD PMID:32244040 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198 		JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions
increases expression		 ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of IRF4 mRNA]
Cannabidiol results in increased expression of IRF4 mRNA		 CTD PMID:27256343 NCBI chr17:34,886,746...34,905,191
Ensembl chr17:34,886,739...34,905,117 		JBrowse link
G Itgb3 integrin subunit beta 3 affects methylation EXP Cannabidiol affects the methylation of ITGB3 gene CTD PMID:30521419 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410 		JBrowse link
G Jak3 Janus kinase 3 affects methylation EXP Cannabidiol affects the methylation of JAK3 gene CTD PMID:30521419 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668 		JBrowse link
G Jaml junction adhesion molecule like multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of JAML mRNA] CTD PMID:27256343 NCBI chr 8:49,378,644...49,408,894
Ensembl chr 8:49,378,644...49,410,088 		JBrowse link
G Jdp2 Jun dimerization protein 2 increases expression ISO Cannabidiol results in increased expression of JDP2 mRNA CTD PMID:21542829 NCBI chr 6:109,464,910...109,505,591
Ensembl chr 6:109,466,060...109,505,161 		JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO Cannabidiol results in decreased expression of KCTD12 mRNA CTD PMID:21542829 NCBI chr15:87,384,632...87,390,627 JBrowse link
G Klf4 Kruppel like factor 4 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of KLF4 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of KLF4 mRNA		 CTD PMID:26504004 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669 		JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases expression EXP Cannabidiol results in decreased expression of KRAS mRNA CTD PMID:32553926 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558 		JBrowse link
G Lamc1 laminin subunit gamma 1 affects methylation EXP Cannabidiol affects the methylation of LAMC1 gene CTD PMID:30521419 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Cannabidiol results in increased expression of LCN2 mRNA CTD PMID:21542829 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546 		JBrowse link
G Limk2 LIM domain kinase 2 affects methylation EXP Cannabidiol affects the methylation of LIMK2 gene CTD PMID:30521419 NCBI chr14:83,564,048...83,641,996
Ensembl chr14:83,573,928...83,641,892 		JBrowse link
G Llgl1 LLGL scribble cell polarity complex component 1 affects methylation EXP Cannabidiol affects the methylation of LLGL1 gene CTD PMID:30521419 NCBI chr10:46,940,873...46,955,524
Ensembl chr10:46,940,965...46,954,674 		JBrowse link
G LOC102553180 protocadherin alpha-1-like increases expression ISO Cannabidiol results in increased expression of PCDHA1 mRNA CTD PMID:21542829 NCBI chr18:29,824,891...29,839,850 JBrowse link
G LOC103689977 caspase-6 decreases expression ISO Cannabidiol results in decreased expression of CASP6 mRNA CTD PMID:33019509 NCBI chr 2:230,186,170...230,198,555
Ensembl chr 2:230,186,198...230,198,555 		JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) increases expression ISO Cannabidiol results in increased expression of HSPA6 mRNA CTD PMID:26504004 NCBI chr13:89,408,703...89,411,500 JBrowse link
G Lpin1 lipin 1 multiple interactions
increases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of LPIN1 mRNA
Cannabidiol results in increased expression of LPIN1 mRNA		 CTD PMID:30742662 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046 		JBrowse link
G Ly86 lymphocyte antigen 86 decreases expression ISO Cannabidiol results in decreased expression of LY86 mRNA CTD PMID:21542829 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436 		JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of MAFB mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of MAFB mRNA		 CTD PMID:30742662 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 affects methylation EXP Cannabidiol affects the methylation of MAP2K1 gene CTD PMID:30521419 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 affects methylation EXP Cannabidiol affects the methylation of MAP2K6 gene CTD PMID:30521419 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Cannabidiol results in decreased expression of MAP3K5 mRNA CTD PMID:33019509 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
affects expression		 ISO Cannabidiol results in increased phosphorylation of MAPK1 protein
tanespimycin affects the reaction [Cannabidiol affects the expression of MAPK1 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of MAPK1 protein]		 CTD PMID:26504004 PMID:28601556 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 decreases expression EXP Cannabidiol results in decreased expression of MAPK14 mRNA CTD PMID:32553926 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
affects expression		 ISO Cannabidiol results in increased phosphorylation of MAPK3 protein
tanespimycin affects the reaction [Cannabidiol affects the expression of MAPK3 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of MAPK3 protein]		 CTD PMID:26504004 PMID:28601556 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975 		JBrowse link
G Mapt microtubule-associated protein tau affects methylation EXP Cannabidiol affects the methylation of MAPT gene CTD PMID:30521419 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517 		JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO Cannabidiol results in decreased expression of MAT2A mRNA CTD PMID:21542829 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
increases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MDM2 mRNA
Cannabidiol results in increased expression of MDM2 mRNA		 CTD PMID:30742662 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328 		JBrowse link
G Mecom MDS1 and EVI1 complex locus affects methylation EXP Cannabidiol affects the methylation of MECOM gene CTD PMID:30521419 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769 		JBrowse link
G Mef2b myocyte enhancer factor 2B increases expression ISO Cannabidiol results in increased expression of MEF2B mRNA CTD PMID:21542829 NCBI chr16:21,001,204...21,017,651
Ensembl chr16:21,001,206...21,017,163 		JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression ISO Cannabidiol results in decreased expression of MEF2C mRNA CTD PMID:21542829 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787 		JBrowse link
G Mir145 microRNA 145 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR145A mRNA CTD PMID:30742662 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994 		JBrowse link
G Mir146a microRNA 146a multiple interactions
decreases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR146 mRNA; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MIR146 mRNA]
Cannabidiol results in decreased expression of MIR146 mRNA		 CTD PMID:30742662 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570 		JBrowse link
G Mir155 microRNA 155 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MIR155 mRNA] CTD PMID:30742662 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667 		JBrowse link
G Mir181b1 microRNA 181b-1 increases expression ISO Cannabidiol results in increased expression of MIR181B-1 mRNA CTD PMID:30742662 NCBI chr13:54,952,903...54,953,012
Ensembl chr13:54,952,903...54,953,012 		JBrowse link
G Mir21 microRNA 21 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR21A mRNA CTD PMID:30742662 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301 		JBrowse link
G Mir221 microRNA 221 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR221 mRNA CTD PMID:30742662 NCBI chr  X:3,684,480...3,684,588
Ensembl chr  X:3,684,480...3,684,588 		JBrowse link
G Mir222 microRNA 222 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR222 mRNA CTD PMID:30742662 NCBI chr  X:3,683,919...3,684,021
Ensembl chr  X:3,683,919...3,684,021 		JBrowse link
G Mir25 microRNA 25 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of MIR25 mRNA CTD PMID:30742662 NCBI chr12:19,307,340...19,307,423
Ensembl chr12:19,307,340...19,307,423 		JBrowse link
G Mir34a microRNA 34a multiple interactions
increases expression		 ISO [Cannabidiol co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MIR34A mRNA
Cannabidiol results in increased expression of MIR34A mRNA		 CTD PMID:30742662 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592 		JBrowse link
G Mir449a microRNA 449a increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of MIR449A mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR449A mRNA		 CTD PMID:30742662 NCBI chr 2:44,897,601...44,897,691
Ensembl chr 2:44,897,601...44,897,691 		JBrowse link
G Mitf melanocyte inducing transcription factor increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of MITF mRNA; Cannabidiol results in increased expression of MITF protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of MITF mRNA]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of MITF mRNA]		 CTD PMID:28601556 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Cannabidiol results in decreased expression of MKI67 protein CTD PMID:24910342 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454 		JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression ISO Cannabidiol results in increased expression of MMP23 mRNA CTD PMID:21542829 PMID:22178458 NCBI chr 5:173,078,811...173,082,834
Ensembl chr 5:173,078,590...173,081,839 		JBrowse link
G Mog myelin oligodendrocyte glycoprotein multiple interactions ISO [Cannabidiol co-treated with MOG protein modified form] results in increased expression of DUSP6 mRNA; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of ATF3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CDK5R1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CREM mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CSRNP1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCL9 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCR1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of DGAT1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of FDPS mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of GPR83 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IER3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IFNGR1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IGFBP4 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL12A mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL1B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of JAML mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of NR4A3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of SPHK1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF18 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF9 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF11 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF14 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TUBB2B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of VPS37B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of XCL1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL1B protein]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL3 protein]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of BTLA mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CD69 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CMPK2 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of DUSP6 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GBP11 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GFOD1 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of IRF4 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of MX2 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of PPIC mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of RSAD2 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TAGAP mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TNFSF8 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TRIM30A mRNA] CTD PMID:27256343 NCBI chr20:2,003,871...2,014,284
Ensembl chr20:2,004,052...2,014,286 		JBrowse link
G Mr1 major histocompatibility complex, class I-related multiple interactions
increases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of MR1 mRNA
Cannabidiol results in increased expression of MR1 mRNA		 CTD PMID:30742662 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841 		JBrowse link
G Mt1 metallothionein 1 increases expression ISO Cannabidiol results in increased expression of MT1 mRNA CTD PMID:27256343 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724 		JBrowse link
G Mt2A metallothionein 2A increases expression ISO Cannabidiol results in increased expression of MT2 mRNA CTD PMID:21542829 PMID:22178458 PMID:27256343 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740 		JBrowse link
G Mx2 MX dynamin like GTPase 2 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of MX2 mRNA] CTD PMID:27256343 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects methylation EXP Cannabidiol affects the methylation of MYC gene CTD PMID:30521419 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Myh6 myosin heavy chain 6 increases expression ISO Cannabidiol results in increased expression of MYHC mRNA CTD PMID:30074247 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699 		JBrowse link
G Myog myogenin multiple interactions
increases expression		 ISO iodoresiniferatoxin inhibits the reaction [Cannabidiol results in increased expression of MYOG mRNA] CTD PMID:30074247 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048 		JBrowse link
G Nckap1l NCK associated protein 1 like affects methylation EXP Cannabidiol affects the methylation of NCKAP1L gene CTD PMID:30521419 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of NDRG1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of NDRG1 mRNA		 CTD PMID:21542829 PMID:22178458 PMID:30742662 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714 		JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 increases expression ISO Cannabidiol results in increased expression of NEURL1A mRNA CTD PMID:21542829 NCBI chr 1:266,953,006...267,038,879
Ensembl chr 1:266,952,561...267,038,883 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 decreases expression ISO Cannabidiol results in decreased expression of NFAM1 mRNA CTD PMID:21542829 NCBI chr 7:123,856,718...123,893,790
Ensembl chr 7:123,856,567...123,892,429 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 decreases expression
multiple interactions		 ISO Cannabidiol results in decreased expression of NFATC2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of NFATC2 mRNA		 CTD PMID:30742662 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292 		JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 increases expression ISO Cannabidiol results in increased expression of NFE2L1 mRNA CTD PMID:21542829 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of NFE2L2 protein
NFE2L2 protein affects the reaction [Cannabidiol results in increased expression of HMOX1 protein]		 CTD PMID:32708634 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO Cannabidiol results in increased expression of NFIL3 mRNA CTD PMID:26504004 NCBI chr17:12,261,102...12,276,316
Ensembl chr17:12,261,102...12,276,315 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression ISO Cannabidiol results in increased expression of NFKB1 mRNA CTD PMID:21542829 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689 		JBrowse link
G Nfkbib NFKB inhibitor beta increases expression ISO Cannabidiol results in increased expression of NFKBIB mRNA CTD PMID:21542829 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions		 ISO
EXP		 Cannabidiol results in increased expression of NOS2 mRNA
Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of NOS2 mRNA]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS2 protein]		 CTD PMID:27430346 PMID:30074247 PMID:30742662 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Cannabidiol results in increased expression of NQO1 mRNA CTD PMID:21542829 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of NR4A3 mRNA] CTD PMID:27256343 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 affects methylation EXP Cannabidiol affects the methylation of NTRK2 gene CTD PMID:30521419 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Cannabidiol results in increased expression of NUPR1 mRNA CTD PMID:21542829 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524 		JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions EXP Cannabidiol inhibits the reaction [naltrindole binds to and results in decreased activity of OPRD1 protein] CTD PMID:16489449 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions EXP Cannabidiol promotes the reaction [Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]] CTD PMID:16489449 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Cannabidiol results in increased cleavage of PARP1 protein CTD PMID:29441458 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716 		JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 decreases expression ISO Cannabidiol results in decreased expression of PARP4 mRNA CTD PMID:33019509 NCBI chr15:36,809,362...36,911,167 JBrowse link
G Pax8 paired box 8 affects methylation EXP Cannabidiol affects the methylation of PAX8 gene CTD PMID:30521419 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946 		JBrowse link
G Pcdha1 protocadherin alpha 1 increases expression ISO Cannabidiol results in increased expression of PCDHA1 mRNA CTD PMID:21542829 NCBI chr18:29,951,094...30,215,896 JBrowse link
G Pcdha11 protocadherin alpha 11 increases expression ISO Cannabidiol results in increased expression of PCDHA11 mRNA CTD PMID:21542829 NCBI chr18:30,017,918...30,215,896
Ensembl chr18:29,987,206...30,215,897 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 increases expression EXP Cannabidiol results in increased expression of PDX1 protein CTD PMID:32553926 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213 		JBrowse link
G Penk proenkephalin multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of PENK mRNA] CTD PMID:17672854 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837 		JBrowse link
G Pfn2 profilin 2 increases expression ISO Cannabidiol results in increased expression of PFN2 mRNA CTD PMID:21542829 NCBI chr 2:147,953,858...147,959,692
Ensembl chr 2:147,955,196...148,050,438 		JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma affects methylation EXP Cannabidiol affects the methylation of PIP5K1C gene CTD PMID:30521419 NCBI chr 7:11,267,207...11,294,291
Ensembl chr 7:11,267,218...11,294,249 		JBrowse link
G Pitpnm2 phosphatidylinositol transfer protein, membrane-associated 2 increases expression ISO Cannabidiol results in increased expression of PITPNM2 mRNA CTD PMID:27256343 NCBI chr12:37,805,332...37,903,856
Ensembl chr12:37,805,332...37,903,855 		JBrowse link
G Pld1 phospholipase D1 decreases expression ISO Cannabidiol results in decreased expression of PLD1 mRNA CTD PMID:33019509 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403 		JBrowse link
G Plin2 perilipin 2 increases expression ISO Cannabidiol results in increased expression of PLIN2 mRNA CTD PMID:21542829 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857 		JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO Cannabidiol results in increased expression of PLK2 mRNA CTD PMID:21542829 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901 		JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression ISO Cannabidiol results in increased expression of PLPP3 mRNA CTD PMID:21542829 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Cannabidiol results in increased expression of PMAIP1 mRNA CTD PMID:26504004 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102 		JBrowse link
G Polr1g RNA polymerase I subunit G decreases expression ISO Cannabidiol results in decreased expression of CD3EAP mRNA CTD PMID:21542829 NCBI chr 1:80,267,725...80,271,001
Ensembl chr 1:80,267,725...80,271,001 		JBrowse link
G Pomgnt2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) decreases expression ISO Cannabidiol results in decreased expression of POMGNT2 mRNA CTD PMID:21542829 NCBI chr 8:130,615,482...130,631,144
Ensembl chr 8:130,615,711...130,617,833 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 affects methylation EXP Cannabidiol affects the methylation of POU5F1 gene CTD PMID:30521419 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects methylation EXP Cannabidiol affects the methylation of PPARD gene CTD PMID:30521419 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
decreases expression
multiple interactions
affects binding		 ISO
EXP		 Cannabidiol results in increased expression of PPARG mRNA
Cannabidiol results in decreased expression of PPARG protein
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of PPARG mRNA
Cannabidiol binds to PPARG protein
Cannabidiol results in increased expression of and affects the localization of PPARG protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Cannabidiol affects the localization of PPARG protein]		 CTD PMID:19285060 PMID:23220503 PMID:28853159 PMID:30742662 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ppic peptidylprolyl isomerase C multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of PPIC mRNA] CTD PMID:27256343 NCBI chr18:48,372,039...48,384,645
Ensembl chr18:48,372,041...48,384,645 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma affects methylation EXP Cannabidiol affects the methylation of PPP1CC gene CTD PMID:30521419 NCBI chr12:39,864,302...39,882,030
Ensembl chr12:39,864,295...39,882,030 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of PPP1R15A mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of PPP1R15A mRNA		 CTD PMID:21542829 PMID:26504004 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974 		JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C increases expression ISO Cannabidiol results in increased expression of PPP1R3C mRNA CTD PMID:26504004 NCBI chr 1:255,371,830...255,376,833
Ensembl chr 1:255,371,810...255,376,833 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha decreases expression ISO Cannabidiol results in decreased expression of PPP3R1 mRNA CTD PMID:33019509 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha affects methylation EXP Cannabidiol affects the methylation of PRKACA gene CTD PMID:30521419 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860 		JBrowse link
G Prkca protein kinase C, alpha increases expression ISO Cannabidiol results in increased expression of PRKCA mRNA CTD PMID:33019509 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947 		JBrowse link
G Prkcb protein kinase C, beta decreases expression ISO Cannabidiol results in decreased expression of PRKCB mRNA CTD PMID:33019509 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831 		JBrowse link
G Prl prolactin multiple interactions ISO Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein] CTD PMID:31154070 PMID:31953017 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions
increases expression		 ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of PSAT1 mRNA
Cannabidiol results in increased expression of PSAT1 mRNA		 CTD PMID:26504004 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941 		JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GABRA1 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of GRIA2 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of SNAP25 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of DLG4 protein]; [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [APP gene mutant form co-treated with PSEN1 gene mutant form] CTD PMID:27567873 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798 		JBrowse link
G Psmb8 proteasome 20S subunit beta 8 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [IFNG protein results in increased expression of PSMB8 protein]; Cannabidiol inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]; Cannabidiol inhibits the reaction [IFNG protein results in increased expression of PSMB8 protein]; Cannabidiol promotes the reaction [Dronabinol inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA]]; Dronabinol promotes the reaction [Cannabidiol inhibits the reaction [IFNG results in increased expression of PSMB8 mRNA]] CTD PMID:27769052 NCBI chr20:3,990,809...3,993,772
Ensembl chr20:3,990,613...3,993,769 		JBrowse link
G Ptch1 patched 1 affects methylation EXP Cannabidiol affects the methylation of PTCH1 gene CTD PMID:30521419 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873 		JBrowse link
G Ptgir prostaglandin I2 receptor increases expression ISO Cannabidiol results in increased expression of PTGIR mRNA CTD PMID:21542829 NCBI chr 1:78,833,449...78,835,832
Ensembl chr 1:78,833,157...78,837,623 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 ISO
EXP		 Cannabidiol results in increased expression of PTGS2 mRNA; Cannabidiol results in increased expression of PTGS2 protein
[Dronabinol co-treated with Cannabidiol] results in increased expression of PTGS2 mRNA
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of PTGS2 mRNA]		 CTD PMID:23220503 PMID:26504004 PMID:27430346 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Ptpn14 protein tyrosine phosphatase, non-receptor type 14 increases expression ISO Cannabidiol results in increased expression of PTPN14 mRNA CTD PMID:21542829 NCBI chr13:108,689,916...108,841,593
Ensembl chr13:108,696,336...108,841,511 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J decreases expression ISO Cannabidiol results in decreased expression of PTPRJ mRNA CTD PMID:30742662 NCBI chr 3:79,233,519...79,390,956
Ensembl chr 3:79,233,525...79,390,956 		JBrowse link
G Pvalb parvalbumin multiple interactions
increases expression		 EXP [Poly I-C co-treated with Cannabidiol] results in increased expression of PVALB protein
Cannabidiol results in increased expression of PVALB protein		 CTD PMID:31202911 PMID:31326506 NCBI chr 7:119,428,657...119,443,674
Ensembl chr 7:119,429,019...119,441,487 		JBrowse link
G Rab3il1 RAB3A interacting protein-like 1 decreases expression ISO Cannabidiol results in decreased expression of RAB3IL1 mRNA CTD PMID:21542829 NCBI chr 1:226,077,182...226,084,830
Ensembl chr 1:226,077,120...226,084,830 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 affects methylation EXP Cannabidiol affects the methylation of RASGRP1 gene CTD PMID:30521419 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of RELA mRNA; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein] CTD PMID:19910459 PMID:30742662 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Cannabidiol results in increased expression of RELB mRNA CTD PMID:21542829 PMID:30742662 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825 		JBrowse link
G Rin2 Ras and Rab interactor 2 decreases expression ISO Cannabidiol results in decreased expression of RIN2 mRNA CTD PMID:21542829 NCBI chr 3:139,871,330...140,087,679
Ensembl chr 3:139,894,331...140,087,678 		JBrowse link
G Rnd3 Rho family GTPase 3 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of RND3 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of RND3 mRNA		 CTD PMID:26504004 NCBI chr 3:36,643,374...36,660,727
Ensembl chr 3:36,642,587...36,660,758 		JBrowse link
G Rora RAR-related orphan receptor A multiple interactions
increases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of RORA mRNA
Cannabidiol results in increased expression of RORA mRNA		 CTD PMID:30742662 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212 		JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Cannabidiol results in decreased phosphorylation of RPS6 protein CTD PMID:28392768 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 multiple interactions
increases expression		 ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of RSAD2 mRNA; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of RSAD2 mRNA]
Cannabidiol results in increased expression of RSAD2 mRNA		 CTD PMID:27256343 PMID:30742662 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 increases expression ISO Cannabidiol results in increased expression of S1PR1 mRNA CTD PMID:30742662 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO Cannabidiol results in increased expression of SARS mRNA CTD PMID:21542829 NCBI chr 2:211,219,743...211,235,475
Ensembl chr 2:211,219,750...211,235,467 		JBrowse link
G Scin scinderin affects methylation EXP Cannabidiol affects the methylation of SCIN gene CTD PMID:30521419 NCBI chr 6:59,975,375...60,055,075
Ensembl chr 6:59,976,003...60,054,279 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression
increases response to substance
decreases secretion
multiple interactions		 ISO Cannabidiol results in decreased expression of SERPINE1 mRNA
SERPINE1 protein results in increased susceptibility to Cannabidiol
Cannabidiol results in decreased secretion of SERPINE1 protein
CNR1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]; CNR2 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]; TRPV1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]		 CTD PMID:20668920 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482 		JBrowse link
G Sesn2 sestrin 2 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of SESN2 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of SESN2 mRNA		 CTD PMID:26504004 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117 		JBrowse link
G Sfxn4 sideroflexin 4 increases expression ISO Cannabidiol results in increased expression of SFXN4 mRNA CTD PMID:21542829 NCBI chr 1:282,213,610...282,236,851
Ensembl chr 1:282,213,675...282,235,974 		JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 decreases expression ISO Cannabidiol results in decreased expression of SHANK1 mRNA CTD PMID:33019509 NCBI chr 1:100,297,137...100,344,377
Ensembl chr 1:100,297,152...100,344,377 		JBrowse link
G Slc18a1 solute carrier family 18 member A1 decreases expression ISO Cannabidiol results in decreased expression of SLC18A1 mRNA CTD PMID:33019509 NCBI chr16:22,358,646...22,395,183
Ensembl chr16:22,361,998...22,395,183 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases expression ISO Cannabidiol results in decreased expression of SLC1A2 mRNA CTD PMID:33019509 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644 		JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO Cannabidiol results in increased expression of SLC1A4 mRNA CTD PMID:21542829 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597 		JBrowse link
G Slc25a22 solute carrier family 25 member 22 decreases expression ISO Cannabidiol results in decreased expression of SLC25A22 mRNA CTD PMID:21542829 NCBI chr 1:214,410,388...214,418,236
Ensembl chr 1:214,410,417...214,414,897 		JBrowse link
G Slc2a6 solute carrier family 2 member 6 increases expression ISO Cannabidiol results in increased expression of SLC2A6 mRNA CTD PMID:21542829 NCBI chr 3:5,567,729...5,575,144
Ensembl chr 3:5,568,321...5,575,136 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of SLC30A1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of SLC30A1 mRNA		 CTD PMID:21542829 PMID:22178458 PMID:27256343 PMID:30742662 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683 		JBrowse link
G Slc32a1 solute carrier family 32 member 1 increases expression ISO Cannabidiol results in increased expression of SLC32A1 mRNA CTD PMID:33019509 NCBI chr 3:155,102,980...155,107,815
Ensembl chr 3:155,103,150...155,107,817 		JBrowse link
G Slc38a1 solute carrier family 38, member 1 decreases expression ISO Cannabidiol results in decreased expression of SLC38A1 mRNA CTD PMID:33019509 NCBI chr 7:137,970,555...138,040,098
Ensembl chr 7:137,975,549...138,039,984 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 decreases expression ISO Cannabidiol results in decreased expression of SLC39A10 mRNA CTD PMID:21542829 PMID:22178458 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552 		JBrowse link
G Slc39a4 solute carrier family 39 member 4 increases expression ISO Cannabidiol results in increased expression of SLC39A4 mRNA CTD PMID:21542829 PMID:22178458 NCBI chr 7:117,675,718...117,682,586
Ensembl chr 7:117,675,720...117,680,004 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Cannabidiol results in increased expression of SLC3A2 mRNA CTD PMID:21542829 PMID:27256343 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression ISO Cannabidiol results in increased expression of SLC40A1 mRNA CTD PMID:21542829 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 decreases expression ISO Cannabidiol results in decreased expression of SLC5A6 mRNA CTD PMID:21542829 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases expression ISO Cannabidiol results in increased expression of SLC6A9 mRNA CTD PMID:21542829 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of SLC7A11 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of SLC7A11 mRNA		 CTD PMID:21542829 PMID:30742662 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162 		JBrowse link
G Snap25 synaptosome associated protein 25 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in decreased susceptibility to [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in decreased expression of SNAP25 protein] CTD PMID:27567873 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400 		JBrowse link
G Sned1 sushi, nidogen and EGF-like domains 1 increases expression ISO Cannabidiol results in increased expression of SNED1 mRNA CTD PMID:21542829 NCBI chr 9:100,380,487...100,439,125
Ensembl chr 9:100,380,515...100,437,056 		JBrowse link
G Soat2 sterol O-acyltransferase 2 increases expression ISO Cannabidiol results in increased expression of SOAT2 mRNA CTD PMID:21542829 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression ISO Cannabidiol results in increased expression of SOCS1 mRNA CTD PMID:30742662 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SOCS3 mRNA] CTD PMID:19910459 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of SOD1 mRNA] CTD PMID:17672854 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of SOD2 mRNA] CTD PMID:17672854 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587 		JBrowse link
G Sox4 SRY-box transcription factor 4 increases expression ISO Cannabidiol results in increased expression of SOX4 mRNA CTD PMID:21542829 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of SPHK1 mRNA] CTD PMID:27256343 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393 		JBrowse link
G Spic Spi-C transcription factor increases expression ISO Cannabidiol results in increased expression of SPIC mRNA CTD PMID:21542829 NCBI chr 7:29,225,721...29,233,452
Ensembl chr 7:29,225,727...29,233,392 		JBrowse link
G Sqstm1 sequestosome 1 increases expression
decreases expression
multiple interactions		 ISO Cannabidiol results in increased expression of SQSTM1 mRNA
Cannabidiol results in decreased expression of SQSTM1 protein
[Dronabinol co-treated with Cannabidiol] results in decreased expression of SQSTM1 protein; Dronabinol promotes the reaction [Cannabidiol results in decreased expression of SQSTM1 protein]		 CTD PMID:21542829 PMID:27769052 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects methylation
increases expression		 EXP
ISO		 Cannabidiol affects the methylation of SRC gene
Cannabidiol results in increased expression of SRC mRNA		 CTD PMID:30521419 PMID:30742662 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Cannabidiol results in increased expression of SRXN1 mRNA CTD PMID:21542829 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Cannabidiol results in decreased expression of ST6GALNAC4 mRNA CTD PMID:21542829 NCBI chr 3:11,607,103...11,619,595
Ensembl chr 3:11,607,225...11,619,593 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Cannabidiol results in increased expression of STAT1 mRNA CTD PMID:30742662 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:19910459 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233 		JBrowse link
G Stx11 syntaxin 11 increases expression ISO Cannabidiol results in increased expression of STX11 mRNA CTD PMID:21542829 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of TAC1 mRNA] CTD PMID:17672854 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819 		JBrowse link
G Tagap T-cell activation RhoGTPase activating protein multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TAGAP mRNA] CTD PMID:27256343 NCBI chr 1:47,493,990...47,503,492
Ensembl chr 1:47,493,994...47,502,952 		JBrowse link
G Tbx3 T-box transcription factor 3 affects methylation EXP Cannabidiol affects the methylation of TBX3 gene CTD PMID:30521419 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526 		JBrowse link
G Tcf7l1 transcription factor 7 like 1 affects methylation EXP Cannabidiol affects the methylation of TCF7L1 gene CTD PMID:30521419 NCBI chr 4:100,492,796...100,660,401
Ensembl chr 4:100,491,798...100,660,140 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]
Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TGFB1 mRNA]		 CTD PMID:30074247 PMID:32049991 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 affects methylation EXP Cannabidiol affects the methylation of TGFB3 gene CTD PMID:30521419 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 affects methylation EXP Cannabidiol affects the methylation of TGFBR2 gene CTD PMID:30521419 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494 		JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of TGIF2 mRNA CTD PMID:30742662 NCBI chr 3:152,906,961...152,924,380
Ensembl chr 3:152,909,189...152,924,377 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of TIMP1 mRNA; Cannabidiol results in increased expression of TIMP1 protein
ICAM1 mutant form inhibits the reaction [Cannabidiol results in increased expression of TIMP1 protein]		 CTD PMID:22198381 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384 		JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor decreases expression ISO Cannabidiol results in decreased expression of TLE1 mRNA CTD PMID:21542829 NCBI chr 5:88,546,607...88,630,277
Ensembl chr 5:88,546,568...88,629,491 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO		 Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of TNF mRNA; Cannabidiol analog inhibits the reaction [Peptidoglycan results in increased expression of TNF protein]; Cannabidiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TNF mRNA]; Cannabidiol inhibits the reaction [DMD gene mutant form results in increased expression of TNF protein]
[Cannabidiol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; Cannabidiol analog inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]		 CTD PMID:21492165 PMID:30074247 PMID:30742662 PMID:30796934 PMID:31054246 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO Cannabidiol results in increased expression of TNFAIP2 mRNA CTD PMID:21542829 NCBI chr 6:135,890,869...135,903,647
Ensembl chr 6:135,890,931...135,903,647 		JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF18 mRNA] CTD PMID:27256343 NCBI chr 5:173,459,371...173,463,980
Ensembl chr 5:173,460,354...173,463,140 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF9 mRNA] CTD PMID:27256343 NCBI chr 5:168,009,245...168,035,813
Ensembl chr 5:168,009,393...168,035,810 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF11 mRNA] CTD PMID:27256343 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704 		JBrowse link
G Tnfsf14 TNF superfamily member 14 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF14 mRNA] CTD PMID:27256343 NCBI chr 9:9,761,363...9,765,461
Ensembl chr 9:9,761,536...9,765,186 		JBrowse link
G Tnfsf8 TNF superfamily member 8 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TNFSF8 mRNA] CTD PMID:27256343 NCBI chr 5:79,664,779...79,691,547
Ensembl chr 5:79,664,765...79,691,258 		JBrowse link
G Tnnt1 troponin T1, slow skeletal type increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of TNNT1 mRNA
iodoresiniferatoxin inhibits the reaction [Cannabidiol results in increased expression of TNNT1 mRNA]		 CTD PMID:30074247 NCBI chr 1:72,889,270...72,899,629
Ensembl chr 1:72,889,270...72,899,659 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions
decreases activity		 ISO Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Dithiothreitol inhibits the reaction [Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]]
Cannabidiol metabolite results in decreased activity of TOP2A protein		 CTD PMID:29272108 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154 		JBrowse link
G Top2b DNA topoisomerase II beta multiple interactions
decreases activity		 ISO Cannabidiol metabolite inhibits the reaction [TOP2B protein results in increased hydrolysis of Adenosine Triphosphate]
Cannabidiol metabolite results in decreased activity of TOP2B protein		 CTD PMID:29272108 NCBI chr15:10,262,972...10,319,741
Ensembl chr15:10,262,651...10,320,233 		JBrowse link
G Tp53 tumor protein p53 decreases expression EXP Cannabidiol results in decreased expression of TP53 mRNA CTD PMID:32553926 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Cannabidiol results in increased expression of TRP53INP1 mRNA CTD PMID:30742662 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888 		JBrowse link
G Tpm3 tropomyosin 3 affects methylation EXP Cannabidiol affects the methylation of TPM3 gene CTD PMID:30521419 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029 		JBrowse link
G Traf1 TNF receptor-associated factor 1 increases expression ISO Cannabidiol results in increased expression of TRAF1 mRNA CTD PMID:21542829 NCBI chr 3:14,003,340...14,022,955
Ensembl chr 3:14,003,340...14,022,672 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 affects methylation EXP Cannabidiol affects the methylation of TRAF3 gene CTD PMID:30521419 NCBI chr 6:135,610,698...135,720,247
Ensembl chr 6:135,610,743...135,718,564 		JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 increases expression ISO Cannabidiol results in increased expression of TRAT1 mRNA CTD PMID:27256343 NCBI chr11:54,619,169...54,661,284
Ensembl chr11:54,619,129...54,662,353 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of TRIB3 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of TRIB3 mRNA		 CTD PMID:21542829 PMID:26504004 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
increases activity		 EXP
ISO		 Cannabidiol binds to and results in increased activity of TRPA1 protein
Cannabidiol results in increased activity of TRPA1 protein		 CTD PMID:18550765 PMID:30074247 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity		 ISO [Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; Cannabidiol inhibits the reaction [Capsaicin binds to TRPV1 protein]; Cannabidiol inhibits the reaction [resiniferatoxin binds to TRPV1 protein]; capsazepine inhibits the reaction [[Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; capsazepine inhibits the reaction [Cannabidiol results in increased activity of TRPV1 protein]; TRPV1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein] CTD PMID:11606325 PMID:20668920 PMID:30074247 PMID:31054246 PMID:31096838 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679 		JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 increases activity
multiple interactions		 ISO
EXP		 Cannabidiol results in increased activity of TRPV2 protein
[Cannabidiol results in increased activity of TRPV2 protein] which results in increased uptake of Calcium
Cannabidiol analog binds to and results in increased activity of TRPV2 protein; Cannabidiol binds to and results in increased activity of TRPV2 protein		 CTD PMID:18550765 PMID:31096838 NCBI chr10:48,903,540...48,925,036
Ensembl chr10:48,903,540...48,925,030 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in increased expression of TSC22D3 mRNA CTD PMID:26504004 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906 		JBrowse link
G Tubb2b tubulin, beta 2B class IIb multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TUBB2B mRNA] CTD PMID:27256343 NCBI chr17:31,441,640...31,444,687
Ensembl chr17:31,441,630...31,482,759 		JBrowse link
G Tyr tyrosinase multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased activity of TYR protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of TYR mRNA]; Cannabidiol results in increased expression of and results in increased activity of TYR protein; SB 203580 inhibits the reaction [Cannabidiol results in increased activity of TYR protein]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of TYR mRNA] CTD PMID:28601556 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of TYRP1 mRNA]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of TYRP1 mRNA]
Cannabidiol results in increased expression of TYRP1 mRNA; Cannabidiol results in increased expression of TYRP1 protein		 CTD PMID:28601556 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ULK1 mRNA] CTD PMID:30074247 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702 		JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression ISO Cannabidiol results in decreased expression of USP2 mRNA CTD PMID:21542829 NCBI chr 8:48,403,985...48,432,525
Ensembl chr 8:48,406,260...48,430,885 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of VEGFA mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of VEGFA mRNA		 CTD PMID:21542829 PMID:30742662 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
G Vegfb vascular endothelial growth factor B affects methylation EXP Cannabidiol affects the methylation of VEGFB gene CTD PMID:30521419 NCBI chr 1:222,237,000...222,242,786
Ensembl chr 1:222,239,022...222,242,644 		JBrowse link
G Vim vimentin multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA] CTD PMID:32049991 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212 		JBrowse link
G Vps37b VPS37B subunit of ESCRT-I multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of VPS37B mRNA] CTD PMID:27256343 NCBI chr12:37,984,790...38,023,369
Ensembl chr12:37,984,790...38,023,368 		JBrowse link
G Vwf von Willebrand factor increases expression ISO Cannabidiol results in increased expression of VWF mRNA CTD PMID:21542829 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523 		JBrowse link
G Wasf2 WASP family member 2 affects methylation EXP Cannabidiol affects the methylation of WASF2 gene CTD PMID:30521419 NCBI chr 5:151,319,382...151,385,051
Ensembl chr 5:151,343,493...151,381,238 		JBrowse link
G Wnt1 Wnt family member 1 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of WNT1 mRNA CTD PMID:30742662 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046 		JBrowse link
G Wnt11 Wnt family member 11 affects methylation EXP Cannabidiol affects the methylation of WNT11 gene CTD PMID:30521419 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756 		JBrowse link
G Wnt7b Wnt family member 7B affects methylation EXP Cannabidiol affects the methylation of WNT7B gene CTD PMID:30521419 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723 		JBrowse link
G Xbp1 X-box binding protein 1 increases expression
multiple interactions		 ISO Cannabidiol results in increased expression of XBP1 mRNA
[Dronabinol co-treated with Cannabidiol] results in increased expression of XBP1 mRNA		 CTD PMID:26504004 PMID:32033040 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of XCL1 mRNA] CTD PMID:27256343 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864 		JBrowse link
cannabidiolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe41 basic helix-loop-helix family, member e41 increases expression ISO cannabidiolic acid results in increased expression of BHLHE41 mRNA CTD PMID:25242400 NCBI chr 4:180,230,742...180,235,138
Ensembl chr 4:180,232,382...180,234,804 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO cannabidiolic acid results in decreased expression of FOS mRNA CTD PMID:27530354 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases expression ISO cannabidiolic acid results in increased expression of HTR1A mRNA CTD PMID:27530354 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO cannabidiolic acid results in decreased expression of ID1 mRNA CTD PMID:25242400 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
decreases expression		 ISO cannabidiolic acid results in increased expression of PPARG mRNA
cannabidiolic acid results in decreased expression of PPARG protein		 CTD PMID:28853159 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 ISO cannabidiolic acid results in decreased expression of PTGS2 mRNA
cannabidiolic acid inhibits the reaction [GW 501516 results in increased expression of PTGS2 mRNA]; cannabidiolic acid promotes the reaction [GSK0660 results in decreased expression of PTGS2 mRNA]		 CTD PMID:25242400 PMID:27530354 PMID:32238697 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO cannabidiolic acid results in increased activity of TRPA1 protein CTD PMID:31096838 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485 		JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 decreases expression ISO cannabidiolic acid results in decreased expression of TRPM8 mRNA CTD PMID:27530354 NCBI chr 9:95,393,370...95,484,528
Ensembl chr 9:95,398,237...95,482,890 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity
multiple interactions		 ISO cannabidiolic acid results in increased activity of TRPV1 protein
[cannabidiolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium		 CTD PMID:31096838 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679 		JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 multiple interactions
increases expression		 ISO [cannabidiolic acid results in increased activity of TRPV2 protein] which results in increased uptake of Calcium
cannabidiolic acid results in increased expression of TRPV2 mRNA		 CTD PMID:27530354 PMID:31096838 NCBI chr10:48,903,540...48,925,036
Ensembl chr10:48,903,540...48,925,030 		JBrowse link
cannabigerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 increases expression ISO cannabigerol results in increased expression of ADCY5 mRNA CTD PMID:33019509 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320 		JBrowse link
G Adcy9 adenylate cyclase 9 decreases expression ISO cannabigerol results in decreased expression of ADCY9 mRNA CTD PMID:33019509 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression ISO cannabigerol results in increased expression of AKT1 mRNA CTD PMID:33019509 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO cannabigerol results in increased expression of ATF4 mRNA CTD PMID:33019509 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO cannabigerol results in increased expression of BCL2L1 mRNA CTD PMID:33019509 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression ISO cannabigerol results in decreased expression of CAMK2B mRNA CTD PMID:33019509 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652 		JBrowse link
G Casp8 caspase 8 decreases expression ISO cannabigerol results in decreased expression of CASP8 mRNA CTD PMID:33019509 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions EXP cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] CTD PMID:22971837 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Clock clock circadian regulator decreases expression ISO cannabigerol results in decreased expression of CLOCK mRNA CTD PMID:33019509 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218 		JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO cannabigerol affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR2 protein] CTD PMID:22971837 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases expression ISO cannabigerol results in decreased expression of CREB1 mRNA CTD PMID:33019509 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435 		JBrowse link
G Dlgap1 DLG associated protein 1 increases expression ISO cannabigerol results in increased expression of DLGAP1 mRNA CTD PMID:33019509 NCBI chr 9:118,277,046...119,159,807
Ensembl chr 9:118,586,179...119,158,196 		JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO cannabigerol results in decreased expression of DRD2 mRNA CTD PMID:33019509 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 decreases expression ISO cannabigerol results in decreased expression of EIF2AK3 mRNA CTD PMID:33019509 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 decreases expression ISO cannabigerol results in decreased expression of ERN1 mRNA CTD PMID:33019509 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Gnai2 G protein subunit alpha i2 increases expression ISO cannabigerol results in increased expression of GNAI2 mRNA CTD PMID:33019509 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307 		JBrowse link
G Gnal G protein subunit alpha L decreases expression ISO cannabigerol results in decreased expression of GNAL mRNA CTD PMID:33019509 NCBI chr18:62,805,406...62,946,133
Ensembl chr18:62,805,410...62,944,630 		JBrowse link
G Gnb4 G protein subunit beta 4 increases expression ISO cannabigerol results in increased expression of GNB4 mRNA CTD PMID:33019509 NCBI chr 2:118,978,965...119,007,877
Ensembl chr 2:118,978,973...119,007,835 		JBrowse link
G Hap1 huntingtin-associated protein 1 increases expression ISO cannabigerol results in increased expression of HAP1 mRNA CTD PMID:33019509 NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:22971837 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:22971837 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO cannabigerol results in decreased expression of MAP3K5 mRNA CTD PMID:33019509 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746 		JBrowse link
G Parp4 poly (ADP-ribose) polymerase family, member 4 decreases expression ISO cannabigerol results in decreased expression of PARP4 mRNA CTD PMID:33019509 NCBI chr15:36,809,362...36,911,167 JBrowse link
G Pld1 phospholipase D1 decreases expression ISO cannabigerol results in decreased expression of PLD1 mRNA CTD PMID:33019509 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
increases expression		 ISO cannabigerol results in decreased expression of PPARG protein
cannabigerol results in increased expression of PPARG mRNA		 CTD PMID:28853159 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha decreases expression ISO cannabigerol results in decreased expression of PPP3R1 mRNA CTD PMID:33019509 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879 		JBrowse link
G Prkca protein kinase C, alpha increases expression ISO cannabigerol results in increased expression of PRKCA mRNA CTD PMID:33019509 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947 		JBrowse link
G Prkcb protein kinase C, beta decreases expression ISO cannabigerol results in decreased expression of PRKCB mRNA CTD PMID:33019509 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831 		JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 decreases expression ISO cannabigerol results in decreased expression of SHANK1 mRNA CTD PMID:33019509 NCBI chr 1:100,297,137...100,344,377
Ensembl chr 1:100,297,152...100,344,377 		JBrowse link
G Slc18a1 solute carrier family 18 member A1 decreases expression ISO cannabigerol results in decreased expression of SLC18A1 mRNA CTD PMID:33019509 NCBI chr16:22,358,646...22,395,183
Ensembl chr16:22,361,998...22,395,183 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases expression ISO cannabigerol results in decreased expression of SLC1A2 mRNA CTD PMID:33019509 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644 		JBrowse link
G Slc32a1 solute carrier family 32 member 1 increases expression ISO cannabigerol results in increased expression of SLC32A1 mRNA CTD PMID:33019509 NCBI chr 3:155,102,980...155,107,815
Ensembl chr 3:155,103,150...155,107,817 		JBrowse link
G Slc38a1 solute carrier family 38, member 1 decreases expression ISO cannabigerol results in decreased expression of SLC38A1 mRNA CTD PMID:33019509 NCBI chr 7:137,970,555...138,040,098
Ensembl chr 7:137,975,549...138,039,984 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:22971837 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity		 ISO [cannabigerol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium CTD PMID:31096838 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679 		JBrowse link
cannabigerolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma increases expression
decreases expression		 ISO cannabigerolic acid results in increased expression of PPARG mRNA
cannabigerolic acid results in decreased expression of PPARG protein		 CTD PMID:28853159 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity		 ISO [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium CTD PMID:31096838 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679 		JBrowse link
Delta(9)-tetrahydrocannabinolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 multiple interactions ISO delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR1 protein]; delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Colforsin results in increased activity of CNR1 protein]]; delta(9)-tetrahydrocannabinolic acid inhibits the reaction [Colforsin results in increased activity of CNR1 protein] CTD PMID:28861508 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR2 protein] CTD PMID:28861508 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP delta(9)-tetrahydrocannabinolic acid results in increased expression of FOSB protein alternative form CTD PMID:18293355 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-nitropropionic acid results in increased expression of IL6 mRNA] CTD PMID:28853159 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-nitropropionic acid results in increased expression of NOS2 mRNA]; T 0070907 inhibits the reaction [delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-nitropropionic acid results in increased expression of NOS2 mRNA]] CTD PMID:28853159 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
increases expression		 ISO delta(9)-tetrahydrocannabinolic acid inhibits the reaction [Rosiglitazone results in increased expression of PPARG mRNA]
delta(9)-tetrahydrocannabinolic acid results in decreased expression of PPARG protein
delta(9)-tetrahydrocannabinolic acid results in increased expression of PPARG mRNA		 CTD PMID:28853159 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO delta(9)-tetrahydrocannabinolic acid results in increased expression of PPARGC1A mRNA CTD PMID:28853159 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-nitropropionic acid results in increased expression of TNF mRNA]; T 0070907 inhibits the reaction [delta(9)-tetrahydrocannabinolic acid inhibits the reaction [3-nitropropionic acid results in increased expression of TNF mRNA]] CTD PMID:28853159 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
HU-308 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of ARG1 mRNA] CTD PMID:29560022 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863 		JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]] CTD PMID:27611972 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140 		JBrowse link
G Becn1 beclin 1 multiple interactions ISO [HU 308 co-treated with Dextran Sulfate] affects the expression of BECN1 protein; HU 308 inhibits the reaction [Glucose results in decreased expression of BECN1 protein]; HU 308 inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of BECN1 protein] CTD PMID:27611972 PMID:30459625 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO 3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein]; [HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein] CTD PMID:27611972 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631 		JBrowse link
G Cd68 Cd68 molecule multiple interactions EXP HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CD68 protein] CTD PMID:29560022 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640 		JBrowse link
G Chi3l3 chitinase 3-like 3 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CHI3L3 mRNA] CTD PMID:29560022 NCBI chr 2:208,899,871...208,936,858
Ensembl chr 2:208,900,103...208,936,860 		JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions EXP
ISO		 HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CNR2 mRNA]; HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CNR2 protein]
[HU 308 co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CNR2 mRNA		 CTD PMID:29560022 PMID:30232034 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP		 HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL10 protein]
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL10 mRNA]		 CTD PMID:29560022 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO		 HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL1B mRNA]
3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein]; [HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]]; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]]; HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]		 CTD PMID:27611972 PMID:29560022 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO		 HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL6 mRNA]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL6 protein]		 CTD PMID:29560022 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of MRC1 protein] CTD PMID:29560022 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP
ISO		 HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of MTOR protein]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of MTOR protein]; HU 308 inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein]		 CTD PMID:29560022 PMID:30459625 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP
ISO		 HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of NFKBIA protein] CTD PMID:29560022 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO [HU 308 co-treated with Dextran Sulfate] affects the expression of NLRP3 protein CTD PMID:27611972 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP		 HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of NOS2 protein] CTD PMID:29560022 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of PIK3R1 protein] CTD PMID:29560022 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [HU 308 co-treated with Dextran Sulfate] affects the expression of SQSTM1 protein; HU 308 inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]; HU 308 inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein] CTD PMID:27611972 PMID:30459625 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO		 HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TGFB1 mRNA]
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TGFB1 protein]		 CTD PMID:29560022 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO		 HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TNF mRNA]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TNF protein]		 CTD PMID:29560022 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
oleoyl ethanolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases export ISO ABCB1 protein results in increased export of N-oleoylethanolamine CTD PMID:30102254 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases response to substance
multiple interactions		 ISO PPARA results in increased susceptibility to N-oleoylethanolamine
N-oleoylethanolamine binds to and results in increased activity of PPARA protein		 CTD PMID:17906680 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO N-oleoylethanolamine results in decreased expression of PTGS2 protein CTD PMID:17906680 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335 		JBrowse link
palmitoyl ethanolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases export ISO ABCB1 protein results in increased export of palmidrol CTD PMID:30102254 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Apob apolipoprotein B affects folding ISO palmidrol affects the folding of APOB protein CTD PMID:16115474 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [palmidrol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA] CTD PMID:31054246 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245 		JBrowse link
G Aqp4 aquaporin 4 affects expression ISO palmidrol affects the expression of AQP4 mRNA CTD PMID:31054246 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996 		JBrowse link
G Cldn3 claudin 3 multiple interactions
decreases expression		 ISO [TNF protein co-treated with IFNG protein co-treated with palmidrol] results in decreased expression of CLDN3 mRNA
palmidrol results in decreased expression of CLDN3 mRNA		 CTD PMID:31054246 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813 		JBrowse link
G Cldn5 claudin 5 decreases expression ISO palmidrol results in decreased expression of CLDN5 mRNA CTD PMID:31054246 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to palmidrol analog CTD PMID:17558434 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Cnr2 cannabinoid receptor 2 affects binding
multiple interactions		 ISO
EXP		 palmidrol binds to CNR2 protein
[SR 144528 binds to and results in decreased activity of CNR2 protein] which results in decreased susceptibility to palmidrol analog		 CTD PMID:10617657 PMID:10688601 PMID:17558434 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein] CTD PMID:26474837 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [palmidrol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; [TNF protein co-treated with IFNG protein co-treated with palmidrol] results in decreased expression of CLDN3 mRNA; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA] CTD PMID:31054246 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein] CTD PMID:26474837 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
affects localization		 EXP [MK-886 binds to and results in decreased activity of PPARA protein] which results in decreased susceptibility to palmidrol analog; [palmidrol co-treated with glyceryl 2-arachidonate] affects the localization of PPARA protein; [palmidrol co-treated with glyceryl 2-arachidonate] affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]
palmidrol affects the localization of PPARA protein		 CTD PMID:17558434 PMID:31787870 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [palmidrol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; [TNF protein co-treated with IFNG protein co-treated with palmidrol] results in decreased expression of CLDN3 mRNA; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA] CTD PMID:31054246 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA] CTD PMID:31054246 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679 		JBrowse link
WIN 55212-2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 decreases expression ISO Win 55212-2 results in decreased expression of ABCA2 mRNA CTD PMID:12237329 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects activity ISO Win 55212-2 affects the activity of ABCG2 protein CTD PMID:30083819 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO Win 55212-2 inhibits the reaction [IL6 protein results in decreased phosphorylation of ACACA protein] CTD PMID:27324222 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression		 ISO JTE 907 inhibits the reaction [Win 55212-2 analog results in decreased expression of ACTA2 protein]; Win 55212-2 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
Win 55212-2 inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Win 55212-2 inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]		 CTD PMID:31901889 PMID:31991773 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394 		JBrowse link
G Adora2a adenosine A2a receptor decreases response to substance EXP ADORA2A protein results in decreased susceptibility to Win 55212-2 CTD PMID:26526685 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 ISO
EXP		 Win 55212-2 results in increased phosphorylation of AKT1 protein
CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of AKT1 protein]; Win 55212-2 results in increased phosphorylation of and results in increased activity of AKT1 protein		 CTD PMID:12734338 PMID:20619260 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO Win 55212-2 results in decreased expression of APAF1 protein CTD PMID:30776504 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Win 55212-2 inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA] CTD PMID:21350020 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Arg1 arginase 1 multiple interactions
affects expression		 ISO AM6545 inhibits the reaction [Win 55212-2 affects the expression of ARG1 mRNA] CTD PMID:30184259 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO Win 55212-2 results in decreased expression of ARHGDIA mRNA CTD PMID:12237329 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550 		JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO GRK2 protein affects the reaction [Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]]; Win 55212-2 affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB1 protein] CTD PMID:31024316 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139 		JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO [Win 55212-2 co-treated with CNR2 protein] affects the localization of ARRB2 protein; Win 55212-2 promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB2 protein] CTD PMID:31024316 PMID:31901889 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134 		JBrowse link
G Becn1 beclin 1 decreases expression ISO Win 55212-2 results in decreased expression of BECN1 protein CTD PMID:30776504 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Casp3 caspase 3 decreases cleavage ISO Win 55212-2 results in decreased cleavage of CASP3 protein CTD PMID:30776504 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp7 caspase 7 decreases cleavage ISO Win 55212-2 results in decreased cleavage of CASP7 protein CTD PMID:30776504 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774 		JBrowse link
G Casp8 caspase 8 decreases cleavage ISO Win 55212-2 results in decreased cleavage of CASP8 protein CTD PMID:30776504 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity		 ISO AM 281 inhibits the reaction [Win 55212-2 results in increased activity of CASP9 protein] CTD PMID:28495606 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Win 55212-2 results in decreased expression of CCT7 mRNA CTD PMID:12237329 NCBI chr 4:117,235,023...117,252,265
Ensembl chr 4:117,235,023...117,252,265 		JBrowse link
G Cdk14 cyclin-dependent kinase 14 increases expression ISO Win 55212-2 results in increased expression of CDK14 mRNA CTD PMID:12237329 NCBI chr 4:25,825,567...26,419,443
Ensembl chr 4:25,825,567...26,419,127 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO Win 55212-2 results in increased expression of CITED2 mRNA; Win 55212-2 results in increased expression of CITED2 protein CTD PMID:12237329 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786 		JBrowse link
G Cldn1 claudin 1 multiple interactions ISO [Win 55212-2 co-treated with Dextran Sulfate] results in decreased expression of CLDN1 protein CTD PMID:27920472 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases response to substance
affects response to substance
decreases expression
affects localization
increases activity
affects binding		 ISO
EXP		 CNR1 affects the reaction [Win 55212-2 results in increased activity of MAPK1 protein]; CNR1 affects the reaction [Win 55212-2 results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [Win 55212-2 results in increased activity of CNR1]; Rimonabant inhibits the reaction [Win 55212-2 results in increased activity of CNR1]; Win 55212-2 affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; Win 55212-2 binds to and results in increased activity of CNR1 protein; Win 55212-2 inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR1 protein]; Win 55212-2 promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]
CNR1 protein results in increased susceptibility to Win 55212-2
CNR1 protein mutant form affects the susceptibility to Win 55212-2
Win 55212-2 results in decreased expression of CNR1 mRNA; Win 55212-2 results in decreased expression of CNR1 protein
Win 55212-2 affects the localization of CNR1 protein
[Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to Win 55212-2; [Win 55212-2 binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; AM 251 inhibits the reaction [Win 55212-2 results in decreased expression of CNR1 mRNA]; AM 251 inhibits the reaction [Win 55212-2 results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [Win 55212-2 inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[Win 55212-2 binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Win 55212-2 binds to and results in increased activity of CNR1 protein
[Win 55212-2 binds to and results in increased activity of CNR1 protein] which results in increased expression of FOS protein; CNRIP1 protein inhibits the reaction [Win 55212-2 affects the localization of CNR1 protein]; Win 55212-2 binds to and results in increased activity of CNR1 protein
Win 55212-2 results in increased activity of CNR1; Win 55212-2 results in increased activity of CNR1 protein
Win 55212-2 binds to CNR1 protein		 CTD PMID:8526880 PMID:10871313 PMID:12421626 PMID:12560108 PMID:16157695 PMID:16438957 PMID:17572696 PMID:21281698 PMID:22044209 PMID:22971837 PMID:27513693 PMID:29113897 PMID:29730318 PMID:29883990 PMID:30165669 PMID:30629988 PMID:31024316 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056 		JBrowse link
G Cnr2 cannabinoid receptor 2 affects response to substance
increases activity
multiple interactions
affects binding		 ISO
EXP		 CNR2 gene SNP affects the susceptibility to Win 55212-2
Win 55212-2 results in increased activity of CNR2 protein
[Win 55212-2 co-treated with CNR2 protein] affects the localization of ARRB2 protein; GRK2 protein affects the reaction [Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]]; ridaifen-B inhibits the reaction [Win 55212-2 binds to and results in increased activity of CNR2 protein]; Win 55212-2 binds to and results in increased activity of CNR2 protein; Win 55212-2 inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR2 protein]; Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]
Win 55212-2 binds to CNR2 protein
[SR 144528 binds to and results in decreased activity of CNR2 protein] which results in decreased susceptibility to Win 55212-2; CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of AKT1 protein]; CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Win 55212-2 binds to and results in increased activity of CNR2 protein		 CTD PMID:10688601 PMID:12734338 PMID:17572696 PMID:20124950 PMID:21281698 PMID:21871882 PMID:22044209 PMID:22971837 PMID:29883990 PMID:29906493 PMID:31024316 PMID:31901889 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Cnrip1 cannabinoid receptor interacting protein 1 multiple interactions ISO CNRIP1 protein inhibits the reaction [Win 55212-2 affects the localization of CNR1 protein] CTD PMID:27513693 NCBI chr14:100,217,547...100,247,235
Ensembl chr14:100,217,289...100,247,235 		JBrowse link
G Ctsd cathepsin D increases expression ISO Win 55212-2 results in increased expression of CTSD protein CTD PMID:30776504 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [Win 55212-2 results in increased expression of DDIT3 mRNA]; methyl-beta-cyclodextrin inhibits the reaction [Win 55212-2 results in increased expression of DDIT3 mRNA] CTD PMID:30502353 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Efs embryonal Fyn-associated substrate decreases expression ISO Win 55212-2 results in decreased expression of EFS mRNA CTD PMID:12237329 NCBI chr15:33,579,952...33,590,217
Ensembl chr15:33,578,381...33,589,522 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation		 ISO RTKI cpd inhibits the reaction [Win 55212-2 results in increased phosphorylation of EGFR protein] CTD PMID:20619260 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Eif4b eukaryotic translation initiation factor 4B decreases expression ISO Win 55212-2 results in decreased expression of EIF4B mRNA CTD PMID:12237329 NCBI chr 7:143,679,656...143,701,452
Ensembl chr 7:143,679,617...143,701,452 		JBrowse link
G Eno2 enolase 2 decreases expression
multiple interactions		 ISO Win 55212-2 results in decreased expression of ENO2 protein
Win 55212-2 inhibits the reaction [IL6 protein results in increased expression of ENO2 protein]		 CTD PMID:27324222 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Win 55212-2 inhibits the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; Win 55212-2 inhibits the reaction [IL1B protein results in increased expression of F3 mRNA] CTD PMID:27556861 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272 		JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
affects expression		 ISO
EXP		 [Acetaminophen co-treated with Win 55212-2] results in decreased expression of FAAH mRNA
Win 55212-2 affects the expression of FAAH mRNA
[Win 55212-2 co-treated with Rimonabant] affects the expression of FAAH mRNA		 CTD PMID:30165669 PMID:32833042 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775 		JBrowse link
G Faahl fatty-acid amide hydrolase-like multiple interactions ISO [Acetaminophen co-treated with Win 55212-2] results in decreased expression of FAAH mRNA CTD PMID:30165669 NCBI chr 5:134,330,204...134,349,400
Ensembl chr 5:134,331,929...134,348,995 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Win 55212-2 binds to and results in increased activity of CNR1 protein] which results in increased expression of FOS protein CTD PMID:12560108 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Gck glucokinase increases expression ISO Win 55212-2 results in increased expression of GCK mRNA; Win 55212-2 results in increased expression of GCK protein CTD PMID:12237329 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO Win 55212-2 inhibits the reaction [amyloid beta-protein (25-35) affects the localization of GJA1 protein] CTD PMID:27757991 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089 		JBrowse link
G Gphn gephyrin multiple interactions EXP Win 55212-2 promotes the reaction [Cocaine results in increased phosphorylation of GPHN protein] CTD PMID:32312805 NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164 		JBrowse link
G Gpr55 G protein-coupled receptor 55 affects response to substance ISO GPR55 protein affects the susceptibility to Win 55212-2 CTD PMID:31877572 NCBI chr 9:92,961,431...93,011,157
Ensembl chr 9:92,962,738...92,963,697 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP Win 55212-2 results in decreased expression of GRIA1 protein CTD PMID:32312805 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Win 55212-2 results in decreased expression of GRIA2 protein