Akr1b7 (aldo-keto reductase family 1, member B7)

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Gene: Akr1b7 (aldo-keto reductase family 1, member B7) Rattus norvegicus

Analyze

Symbol:

Akr1b7

Name:

aldo-keto reductase family 1, member B7

RGD ID:

620257

Description:

Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be involved in prostaglandin metabolic process. Predicted to be active in cytosol and mitochondrion. Orthologous to human AKR1B10 (aldo-keto reductase family 1 member B10) and AKR1B15 (aldo-keto reductase family 1 member B15); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Akr1b14; aldehyde reductase; aldo-keto reductase family 1 member B7; aldose reductase-like protein AKR1B14; aldose reductase-related protein 1; androgen regulated vas deferens protein; Avdp; LOC103692098; MVDP; uncharacterized LOC103692098

RGD Orthologs

Mouse

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Akr1b7 (aldo-keto reductase family 1, member B7)	RGD	RGD
Other homologs ²
Homo sapiens (human):	AKR1B10 (aldo-keto reductase family 1 member B10)	HGNC	Ensembl, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Homo sapiens (human):	AKR1B15 (aldo-keto reductase family 1 member B15)	HGNC	OMA, OrthoDB, Panther, PhylomeDB, Treefam
Alliance orthologs ³
Mus musculus (house mouse):	Akr1b7 (aldo-keto reductase family 1, member B7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	AKR1B10 (aldo-keto reductase family 1 member B10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	AKR1B15 (aldo-keto reductase family 1 member B15)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	akr1b1.2 (aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2)	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG12766	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG2767	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Drosophila melanogaster (fruit fly):	CG6083	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG6084	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	CG9436	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	GCY1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	GRE3	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	Y39G8B.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	YPR1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	YJR096W	Alliance	DIOPT (Ensembl Compara\|OMA\|TreeFam)
Drosophila melanogaster (fruit fly):	ARY	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG10638	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG10863	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	C07D8.6	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	63,053,560 - 63,100,934 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	4	63,076,800 - 63,089,502 (+)	Ensembl
Rnor_6.0	4	61,850,256 - 61,879,733 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	61,850,348 - 61,862,526 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	61,587,891 - 61,600,050 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	61,794,352 - 61,806,916 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	62,070,338 - 62,083,041 (+)	NCBI
Celera	4	58,130,320 - 58,142,884 (+)	NCBI		Celera
Cytogenetic Map	4	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrotoluene (EXP)

4-nitrophenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (EXP,ISO)

all-trans-retinal (ISO)

ammonium chloride (EXP)

antimycin A (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

cadmium dichloride (EXP)

cannabidiol (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

choline (ISO)

cobalt dichloride (EXP)

cyanocob(III)alamin (ISO)

cyproconazole (ISO)

decabromodiphenyl ether (EXP)

dexamethasone (EXP)

dibutyl phthalate (EXP)

doramapimod (ISO)

epoxiconazole (ISO)

ethanol (ISO)

flavonoids (EXP)

flurbiprofen (ISO)

folic acid (ISO)

fumonisin B1 (ISO)

furan (EXP)

glycine betaine (ISO)

GW 4064 (ISO)

L-methionine (ISO)

N-nitrosodiethylamine (EXP,ISO)

ochratoxin A (EXP)

p-chloromercuribenzenesulfonic acid (EXP)

paclitaxel (EXP)

paracetamol (EXP)

PCB138 (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

prednisolone (EXP)

pregnenolone 16alpha-carbonitrile (ISO)

propiconazole (ISO)

rotenone (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium dichromate (EXP)

sodium fluoride (ISO)

Tesaglitazar (EXP)

testosterone (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

tributylstannane (ISO)

trichloroethene (EXP,ISO)

triphenyl phosphate (EXP)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

prostaglandin metabolic process (IEA)

Cellular Component

cytosol (IBA)

mitochondrion (IBA)

Molecular Function

alditol:NADP+ 1-oxidoreductase activity (IBA,TAS)

aldo-keto reductase (NADP) activity (TAS)

prostaglandin H2 endoperoxidase reductase activity (IEA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Kotokorpi P, etal., Endocrinology 2004 Dec;145(12):5704-13. Epub 2004 Sep 9.
3.	MGD data from the GO Consortium
4.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	RGD automated data pipeline
6.	RGD automated import pipeline for gene-chemical interactions
7.	Val P, etal., Endocrinology 2002 Sep;143(9):3435-48.

Additional References at PubMed

PMID:12477932	PMID:19342790	PMID:19809495	PMID:21586312	PMID:22505406	PMID:25577493

Genomics

Comparative Map Data

Akr1b7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	63,053,560 - 63,100,934 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	4	63,076,800 - 63,089,502 (+)	Ensembl
Rnor_6.0	4	61,850,256 - 61,879,733 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	61,850,348 - 61,862,526 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	61,587,891 - 61,600,050 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	61,794,352 - 61,806,916 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	62,070,338 - 62,083,041 (+)	NCBI
Celera	4	58,130,320 - 58,142,884 (+)	NCBI		Celera
Cytogenetic Map	4	q22	NCBI

Akr1b7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	34,389,297 - 34,400,072 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	34,389,269 - 34,400,077 (+)	Ensembl
GRCm38	6	34,412,362 - 34,423,137 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	34,412,334 - 34,423,142 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	34,362,362 - 34,373,137 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	34,342,548 - 34,353,300 (+)	NCBI			mm8
Celera	6	34,408,772 - 34,419,547 (+)	NCBI		Celera
Cytogenetic Map	6	B1	NCBI
cM Map	6	14.95	NCBI

Position Markers

RH140894

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	63,089,196 - 63,089,376 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	61,862,221 - 61,862,400	NCBI	Rnor6.0
Rnor_5.0	4	61,599,740 - 61,599,919	UniSTS	Rnor5.0
RGSC_v3.4	4	61,806,606 - 61,806,785	UniSTS	RGSC3.4
Celera	4	58,142,574 - 58,142,753	UniSTS
RH 3.4 Map	4	374.0	UniSTS
Cytogenetic Map	4	q22	UniSTS

BF390404

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	63,082,594 - 63,082,744 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	61,855,559 - 61,855,708	NCBI	Rnor6.0
Rnor_5.0	4	61,593,078 - 61,593,227	UniSTS	Rnor5.0
RGSC_v3.4	4	61,800,004 - 61,800,153	UniSTS	RGSC3.4
Celera	4	58,135,972 - 58,136,121	UniSTS
RH 3.4 Map	4	398.2	UniSTS
Cytogenetic Map	4	q22	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
619616	Bp79	Blood pressure QTL 79		0.0292	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	5214602	78882945	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5214602	146446691	Rat
1358203	Stl19	Serum triglyceride level QTL 19	2.8	0.002	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	5218294	65958103	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	10814170	91360527	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
6909122	Insul22	Insulin level QTL 22	4.63		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	4	26907285	75585128	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	26907285	75585128	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	29494195	81006281	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	32583980	114627242	Rat
8552782	Vie1	Viral induced encephalitis QTL 1	26.4		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
8552801	Bw143	Body weight QTL 143	7.3		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	34430484	82490359	Rat
8552809	Vie5	Viral induced encephalitis QTL 5	25.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	36303261	103194984	Rat
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	38465774	146803430	Rat
61475	Aia2	Adjuvant induced arthritis QTL 2	5.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	39505275	73892441	Rat
1331807	Rf31	Renal function QTL 31	2.988		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	4	39524264	74726312	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	39524264	116179656	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	40433388	85433388	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	40433414	85433414	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	43457976	88457976	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	44463720	155883716	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	44463908	148090542	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	44463908	148090542	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	0.006	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	4	45456990	146803430	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	50119848	146803430	Rat
4889969	Bss96	Bone structure and strength QTL 96	4.9		tibia size trait (VT:0100001)	tibia cortical bone volume (CMO:0001725)	4	56647776	78882945	Rat
4889972	Bss97	Bone structure and strength QTL 97	5.6		tibia size trait (VT:0100001)	tibia total bone volume (CMO:0001724)	4	56647776	78882945	Rat
5685009	Bmd86	Bone mineral density QTL 86	3.7		tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	4	56647776	78882945	Rat
5685012	Bmd87	Bone mineral density QTL 87	5.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	4	56647776	78882945	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	56647873	149491524	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	56698790	126192555	Rat
631546	Bp86	Blood pressure QTL 86	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	57114432	91360801	Rat
634311	Sach7	Saccharin preference QTL 7			taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	57114432	102114432	Rat
61336	Bp21	Blood pressure QTL 21	4.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	57114705	78881294	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	57486946	102486946	Rat
1558651	Swd3	Spike wave discharge measurement QTL 3	4.62	0.000024	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	4	58432133	92991462	Rat
631671	Iddm11	Insulin dependent diabetes mellitus QTL 11	3.6	0.0012	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	58635877	78886137	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	59948935	154902892	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
1578657	Bss12	Bone structure and strength QTL 12	8.9		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	4	60220938	105220938	Rat
1578658	Bss13	Bone structure and strength QTL 13	8		femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	4	60220938	105220938	Rat
2300179	Bmd50	Bone mineral density QTL 50	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	4	60928534	105928534	Rat
1549843	Bw53	Body weight QTL 53		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	61697658	103194791	Rat
1549839	Bw52	Body weight QTL 52		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	61697658	115089733	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	62277855	128289560	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	62879517	107879517	Rat
7394826	Bw126	Body weight QTL 126		0.002	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	62933269	87483707	Rat
8552807	Vie4	Viral induced encephalitis QTL 4	7.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	62933508	82490359	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	62933508	114921294	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	62933508	114921294	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	62933508	114921294	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	percent change in mean arterial blood pressure (CMO:0002035)	4	62933508	114921294	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	percent change in systolic blood pressure (CMO:0000747)	4	62933508	114921294	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in pulse pressure (CMO:0001882)	4	62933508	114921294	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	4	62933508	114921294	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	28
Count of miRNA genes:	27
Interacting mature miRNAs:	28
Transcripts:	ENSRNOT00000013423
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High			8								1
Medium			17	17		17				4	11
Low		8	12	4	16	4	8	8	25	8	25	8	8
Below cutoff	1	13	8	8	3	8		3	33	8	4	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053781	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001837478	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF182168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000013133 ⟹ ENSRNOP00000013133

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	63,076,800 - 63,086,580 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000013423 ⟹ ENSRNOP00000013423

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	63,076,800 - 63,089,502 (+)	Ensembl
Rnor_6.0 Ensembl	4	61,850,348 - 61,862,526 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000102062 ⟹ ENSRNOP00000085173

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	63,076,800 - 63,087,204 (+)	Ensembl

RefSeq Acc Id:

NM_053781 ⟹ NP_446233

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	4	63,076,943 - 63,089,507 (+)	NCBI
Rnor_6.0	4	61,850,491 - 61,862,531 (+)	NCBI
Rnor_5.0	4	61,587,891 - 61,600,050 (+)	NCBI
RGSC_v3.4	4	61,794,352 - 61,806,916 (+)	RGD
Celera	4	58,130,320 - 58,142,884 (+)	RGD

Sequence:

show sequence

CATACTTTGCAGCAACCATGACAACCTTCGTGAAGCTCAGAACCAAAGCCAAGATGCCCCTGGT
GGGCCTGGGCACCTGGAAGTCTCCCCCAGGCCAAGTCAAGGAAGCTGTGAAGGCAGCCATTGAT
GCTGGATATCGCCACTTTGACTGTGCCTATGTGTATCAGAATGAGAGTGAGGTGGGAGAAGCCA
TCCAAGAGAAGATCAAAGAGAAGGCTGTGAGGCGGGAGGACCTCTTCATCGTCAGCAAGCTGTG
GTCCACTTTCTTTGAGAAAAGCCTGATGAAGGAAGCCTTCCAGAAAACTCTCTCAGATCTGAAG
CTGGACTATCTGGACCTGTATCTAATTCACTGGCCACAGGGACTTCAGGCTGGGAAAGAATTCC
TACCCAAAGACAGTCAAGGCAAAGTTCTCATGAGTAAATCCACGTTCTTGGATGCCTGGGAGGG
CATGGAGGAACTGGTGGACCAGGGGCTGGTGAAAGCTTTGGGCGTCTCCAACTTCAACCACTTC
CAGATCGAAAGGCTCCTGAATAAGCCTGGACTGAAACATAAGCCAGTGACCAATCAGGTCGAGT
GCCACCCTTACCTCACCCAGGAAAAACTGATCCAGTACTGTCACTCCAAGGGCATCGCGGTCAT
AGCCTACAGTCCCCTGGGCTCCCCAGACAGGCCTTATGCTAAGCCTGAGGACCCCGTAGTGCTA
GAGATTCCCAAGATCAAAGAGATTGCTGCAAAGCATAAGAAAACAATAGCTCAGGTTCTGATTC
GATTCCATGTCCAAAGGAACGTGGCAGTGATCCCCAAGTCTGTGACACTCTCACACATAAAGGA
GAACATTCAGGTCTTTGACTTCCAGTTGAGTGAGGAGGACATGGCCGCCATTCTCAGCCTCAAC
AGGAACTGGAGGGCCTGTGGCCTGTTTGTCACAAGCGATGAAGAGGACTTTCCTTTCCACGAGG
AATACTGATGTTGGTTCGCTTGATGAGATTCAAGCCGGGTAGATTCCTTTGTCCTTGTGTGAGA
CTCACTCCTCCTGAAGCAGATTTTAGCCACGTCTCTCTAAAATCAACCTGGATGTAGGCTACCA
TTTGGCCATGTAGGATTTAAATTTTTGTGTTCATCAAGGTGCAGACTCTCACAGGGAAAAGTGA
GTCCAGAGAAACTAAGGTCAATGGTTTTCACTAATGAGGGCTGAGCAAATGTTTCTCATCAGGA
ATGCATTACCATGGTAACACTGGAGACACAGAGATAAAACAATAAAATGTAATAACAGTAAAAA
CAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039106919 ⟹ XP_038962847

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	4	63,053,560 - 63,089,507 (+)	NCBI

RefSeq Acc Id:

XM_039106920 ⟹ XP_038962848

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	4	63,053,560 - 63,100,934 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_446233	(Get FASTA)	NCBI Sequence Viewer
	XP_038962847	(Get FASTA)	NCBI Sequence Viewer
	XP_038962848	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD56034	(Get FASTA)	NCBI Sequence Viewer
	AAH86563	(Get FASTA)	NCBI Sequence Viewer
	EDM15308	(Get FASTA)	NCBI Sequence Viewer
	Q5RJP0	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_446233 ⟸ NM_053781

- UniProtKB:

Q5RJP0 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MTTFVKLRTKAKMPLVGLGTWKSPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQEKIK
EKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGKEFLPKDSQ
GKVLMSKSTFLDAWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLT
QEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVLEIPKIKEIAAKHKKTIAQVLIRFHVQR
NVAVIPKSVTLSHIKENIQVFDFQLSEEDMAAILSLNRNWRACGLFVTSDEEDFPFHEEY

hide sequence

RefSeq Acc Id:

ENSRNOP00000013423 ⟸ ENSRNOT00000013423

RefSeq Acc Id:	XP_038962848 ⟸ XM_039106920
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038962847 ⟸ XM_039106919
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000013133 ⟸ ENSRNOT00000013133

RefSeq Acc Id:

ENSRNOP00000085173 ⟸ ENSRNOT00000102062

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5RJP0-F1-model_v2	AlphaFold	Q5RJP0	1-316	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (MRatBN7.2)

ACI/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620257	AgrOrtholog
BioCyc Gene	G2FUF-45276	BioCyc
Ensembl Genes	ENSRNOG00000009875	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000013423	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000013423	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	3.20.20.100	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7307075	IMAGE-MGC_LOAD
InterPro	Aldo/ket_reductase_CS	UniProtKB/Swiss-Prot
	Aldo/keto_reductase	UniProtKB/Swiss-Prot
	NADP_OxRdtase_dom	UniProtKB/Swiss-Prot
	NADP_OxRdtase_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:116463	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105361	IMAGE-MGC_LOAD
NCBI Gene	116463	ENTREZGENE
Pfam	Aldo_ket_red	UniProtKB/Swiss-Prot
PhenoGen	Akr1b7	PhenoGen
PIRSF	AKR	UniProtKB/Swiss-Prot
PRINTS	ALDKETRDTASE	UniProtKB/Swiss-Prot
PROSITE	ALDOKETO_REDUCTASE_1	UniProtKB/Swiss-Prot
	ALDOKETO_REDUCTASE_2	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF51430	UniProtKB/Swiss-Prot
UniProt	ALD1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Akr1b7	aldo-keto reductase family 1, member B7	LOC103692098	uncharacterized LOC103692098	Data Merged	737654	PROVISIONAL
2014-08-25	LOC103692098	uncharacterized LOC103692098			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-09-10	Akr1b7	aldo-keto reductase family 1, member B7	Avdp	androgen regulated vas deferens protein	Symbol and Name updated	1299863	APPROVED
2002-08-07	Avdp	androgen regulated vas deferens protein			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in adrenal cortex and vas deferens	628357
gene_function	reduces isocaproaldehyde produced by cholesterol side chain cleavage in steroidogenesis
gene_process	involved in detoxification of steroidogenesis byproduct	628357
gene_process	reduces isocaproaldehyde produced by cholesterol side chain cleavage in steroidogenesis	628357
gene_product	member of aldo-keto-redcutase superfamily	628357
gene_protein	316 aa (predicted)	628357
gene_regulation	expression regulated by ACTH; androgen-insensitive expression in rat vas deferens	628357
gene_transcript	948 bp long ORF;rat promoter lacks 77-bp LINE-derived sequence seen in mouse and rat gene transcription initiation sites different from that of mouse	628357

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