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Gene: Rps6ka3 (ribosomal protein S6 kinase A3) Rattus norvegicus
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Symbol: Rps6ka3
Name: ribosomal protein S6 kinase A3
Description: Predicted to have cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein kinase binding activity; and ribosomal protein S6 kinase activity. Predicted to be involved in several processes, including negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; response to lipopolysaccharide; and toll-like receptor signaling pathway. Predicted to localize to the ribosome. Human ortholog(s) of this gene implicated in Coffin-Lowry syndrome; intellectual disability; and non-syndromic X-linked intellectual disability. Orthologous to human RPS6KA3 (ribosomal protein S6 kinase A3); PARTICIPATES IN platelet-derived growth factor signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; long term potentiation; INTERACTS WITH 1,3-dinitrobenzene; bisphenol A; cobalt dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC501560; RGD1563860; ribosomal protein S6 kinase alpha-3; ribosomal protein S6 kinase polypeptide 3; similar to ribosomal protein S6 kinase 2
Orthologs:
Homo sapiens (human) : RPS6KA3 (ribosomal protein S6 kinase A3)  HGNC  Alliance
Mus musculus (house mouse) : Rps6ka3 (ribosomal protein S6 kinase polypeptide 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rps6ka3 (ribosomal protein S6 kinase A3)
Pan paniscus (bonobo/pygmy chimpanzee) : RPS6KA3 (ribosomal protein S6 kinase A3)
Canis lupus familiaris (dog) : RPS6KA3 (ribosomal protein S6 kinase A3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rps6ka3 (ribosomal protein S6 kinase A3)
Sus scrofa (pig) : RPS6KA3 (ribosomal protein S6 kinase A3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X37,469,736 - 37,576,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X37,777,188 - 37,880,963 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X56,722,878 - 56,825,444 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX36,172,781 - 36,274,458 (-)NCBICelera
Cytogenetic MapXq14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rps6ka3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563860
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.