(+)-pilocarpine increases expression ISO RGD:1550017 6480464 Pilocarpine results in increased expression of PRKCB protein CTD PMID:18774262 (+)-pilocarpine decreases expression EXP 6480464 Pilocarpine results in decreased expression of PRKCB mRNA CTD PMID:17971868 (+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of PRKCB protein CTD PMID:15058486 (9R)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione decreases activity ISO RGD:731404 6480464 ruboxistaurin results in decreased activity of PRKCB protein CTD PMID:25634538 (9R)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione multiple interactions EXP 6480464 ruboxistaurin inhibits the reaction [Glucose results in increased phosphorylation of and results in increased activity of PRKCB protein] CTD PMID:19587355 (S)-naringenin multiple interactions ISO RGD:731404 6480464 naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCB protein] CTD PMID:25866363 (S)-nicotine affects localization ISO RGD:731404 6480464 Nicotine affects the localization of PRKCB protein CTD PMID:17003101 1,1-dichloroethene increases expression ISO RGD:1550017 6480464 vinylidene chloride results in increased expression of PRKCB mRNA CTD PMID:26682919 1,2-dichloroethane affects expression ISO RGD:1550017 6480464 ethylene dichloride affects the expression of PRKCB mRNA CTD PMID:28960355 1,2-dimethylhydrazine increases expression ISO RGD:1550017 6480464 1, 2-Dimethylhydrazine results in increased expression of PRKCB mRNA CTD PMID:22206623 1,4-benzoquinone increases expression ISO RGD:731404 6480464 quinone results in increased expression of PRKCB protein CTD PMID:31958493 1-chloro-2,4-dinitrobenzene affects localization ISO RGD:731404 6480464 Dinitrochlorobenzene affects the localization of PRKCB protein CTD PMID:24136171 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of PRKCB mRNA CTD PMID:25380136 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of PRKCB mRNA CTD PMID:17351261 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of PRKCB mRNA CTD PMID:20068009 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731404 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PRKCB mRNA CTD PMID:19684285 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1550017 6480464 PRKCB protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9 more ... CTD PMID:10037446 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PRKCB mRNA CTD PMID:20959002 , PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731404 6480464 Tetrachlorodibenzodioxin results in increased expression of PRKCB mRNA CTD PMID:11007951 , PMID:19684285 2,3,7,8-tetrachlorodibenzodioxine affects localization EXP 6480464 Tetrachlorodibenzodioxin affects the localization of PRKCB protein CTD PMID:16797713 2,3,7,8-tetrachlorodibenzodioxine increases localization EXP 6480464 Tetrachlorodibenzodioxin results in increased localization of PRKCB protein CTD PMID:17222441 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 AHR protein affects the reaction [Tetrachlorodibenzodioxin affects the localization of PRKCB protein] more ... CTD PMID:16797713 , PMID:17222441 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1550017 6480464 Tetrachlorodibenzodioxin results in increased expression of PRKCB mRNA CTD PMID:19465110 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of PRKCB mRNA CTD PMID:21346803 3,4-methylenedioxymethamphetamine increases expression ISO RGD:1550017 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of PRKCB mRNA CTD PMID:19285098 more ... 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:731404 6480464 bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form], bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of PRKCB protein] CTD PMID:16285992 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of PRKCB mRNA CTD PMID:20409345 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of PRKCB mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of PRKCB mRNA CTD PMID:25380136 4-hydroxyphenyl retinamide increases expression ISO RGD:1550017 6480464 Fenretinide results in increased expression of PRKCB mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine affects expression ISO RGD:731404 6480464 Decitabine affects the expression of PRKCB mRNA CTD PMID:23300844 7,12-dimethyltetraphene multiple interactions ISO RGD:1550017 6480464 PRKCB protein inhibits the reaction [CYP1B1 protein results in increased metabolism of 9 more ... CTD PMID:10037446 acetaldehyde multiple interactions ISO RGD:731404 6480464 PRKCB protein affects the reaction [EGF protein inhibits the reaction [Acetaldehyde results in increased transport of Inulin]], PRKCB protein affects the reaction [EGF protein results in decreased susceptibility to Acetaldehyde] CTD PMID:17991733 acetamide increases expression EXP 6480464 acetamide results in increased expression of PRKCB mRNA CTD PMID:31881176 acetylsalicylic acid multiple interactions ISO RGD:731404 6480464 Aspirin inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] CTD PMID:17644113 acetylsalicylic acid affects expression ISO RGD:731404 6480464 Aspirin affects the expression of PRKCB protein CTD PMID:17644113 acrylamide affects expression EXP 6480464 Acrylamide affects the expression of PRKCB mRNA CTD PMID:28959563 aldehydo-D-glucose multiple interactions ISO RGD:731404 6480464 5 more ... CTD PMID:16285992 , PMID:20578705 aldehydo-D-glucose increases expression ISO RGD:731404 6480464 Glucose results in increased expression of PRKCB protein, Glucose results in increased expression of PRKCB protein alternative form CTD PMID:16285992 aldehydo-D-glucose increases activity ISO RGD:731404 6480464 Glucose results in increased activity of PRKCB protein CTD PMID:20578705 aldehydo-D-glucose increases phosphorylation ISO RGD:731404 6480464 Glucose results in increased phosphorylation of PRKCB protein CTD PMID:22162761 aldehydo-D-glucose multiple interactions EXP 6480464 Glucose results in increased phosphorylation of and results in increased activity of PRKCB protein more ... CTD PMID:19587355 all-trans-retinoic acid increases phosphorylation ISO RGD:1550017 6480464 Tretinoin results in increased phosphorylation of PRKCB protein CTD PMID:19476501 all-trans-retinoic acid multiple interactions ISO RGD:731404 6480464 Tretinoin promotes the reaction [arsenic trioxide results in increased expression of PRKCB mRNA] CTD PMID:10673743 all-trans-retinoic acid increases expression ISO RGD:731404 6480464 Tretinoin results in increased expression of PRKCB mRNA CTD PMID:15498508 , PMID:16054129 all-trans-retinoic acid increases phosphorylation ISO RGD:731404 6480464 Tretinoin results in increased phosphorylation of PRKCB protein CTD PMID:19476501 alpha-naphthoflavone multiple interactions EXP 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of PRKCB protein], alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased localization of PRKCB protein] CTD PMID:16797713 , PMID:17222441 alpha-Zearalanol multiple interactions ISO RGD:731404 6480464 ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate inhibits the reaction [Zeranol results in increased phosphorylation of PRKCB protein] CTD PMID:27224899 alpha-Zearalanol increases phosphorylation ISO RGD:731404 6480464 Zeranol results in increased phosphorylation of PRKCB protein CTD PMID:27224899 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PRKCB mRNA CTD PMID:16483693 ammonium chloride decreases expression EXP 6480464 Ammonium Chloride results in decreased expression of PRKCB protein CTD PMID:16483693 amphetamine affects expression EXP 6480464 Amphetamine affects the expression of PRKCB mRNA CTD PMID:16101753 antirheumatic drug decreases expression ISO RGD:731404 6480464 Antirheumatic Agents results in decreased expression of PRKCB mRNA CTD PMID:24449571 Aroclor 1254 decreases expression ISO RGD:1550017 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of PRKCB mRNA CTD PMID:23650126 arsane affects methylation ISO RGD:731404 6480464 Arsenic affects the methylation of PRKCB gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:731404 6480464 Arsenic affects the methylation of PRKCB gene CTD PMID:25304211 arsenite(3-) decreases expression ISO RGD:1550017 6480464 arsenite results in decreased expression of PRKCB mRNA CTD PMID:18191166 arsenous acid multiple interactions ISO RGD:731404 6480464 Tretinoin promotes the reaction [Arsenic Trioxide results in increased expression of PRKCB mRNA] CTD PMID:10673743 arsenous acid affects response to substance ISO RGD:731404 6480464 PRKCB mRNA affects the susceptibility to Arsenic Trioxide CTD PMID:23911876 arsenous acid increases expression ISO RGD:731404 6480464 Arsenic Trioxide results in increased expression of PRKCB mRNA CTD PMID:10673743 , PMID:29442453 arsenous acid decreases expression ISO RGD:731404 6480464 Arsenic Trioxide results in decreased expression of PRKCB mRNA CTD PMID:15725085 Bandrowski's base increases expression ISO RGD:731404 6480464 Bandrowski's base results in increased expression of PRKCB protein CTD PMID:31958493 benzo[a]pyrene decreases expression ISO RGD:731404 6480464 Benzo(a)pyrene results in decreased expression of PRKCB mRNA CTD PMID:20064835 benzo[a]pyrene decreases methylation ISO RGD:731404 6480464 Benzo(a)pyrene results in decreased methylation of PRKCB 3' UTR, Benzo(a)pyrene results in decreased methylation of PRKCB promoter CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:731404 6480464 Benzo(a)pyrene results in increased methylation of PRKCB exon CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:731404 6480464 Benzo(a)pyrene metabolite results in increased expression of PRKCB mRNA CTD PMID:26314263 benzo[a]pyrene decreases expression ISO RGD:1550017 6480464 Benzo(a)pyrene results in decreased expression of PRKCB mRNA CTD PMID:21569818 bis(2-chloroethyl) sulfide decreases expression ISO RGD:1550017 6480464 Mustard Gas results in decreased expression of PRKCB mRNA CTD PMID:15674843 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PRKCB mRNA CTD PMID:25181051 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PRKCB mRNA CTD PMID:30816183 bryostatin 1 multiple interactions ISO RGD:731404 6480464 [bryostatin 1 co-treated with mezerein] results in decreased expression of PRKCB protein, [bryostatin 1 co-treated with mezerein] results in decreased expression of PRKCB protein alternative form CTD PMID:8892972 bryostatin 1 decreases expression ISO RGD:731404 6480464 bryostatin 1 results in decreased expression of PRKCB protein, bryostatin 1 results in decreased expression of PRKCB protein alternative form CTD PMID:8892972 bupivacaine multiple interactions EXP 6480464 [Bupivacaine co-treated with Tetrodotoxin co-treated with Dexamethasone] results in decreased expression of PRKCB mRNA CTD PMID:22341215 buta-1,3-diene decreases expression ISO RGD:1550017 6480464 1, 3-butadiene results in decreased expression of PRKCB mRNA CTD PMID:29038090 butan-1-ol affects localization ISO RGD:731404 6480464 1-Butanol affects the localization of PRKCB protein CTD PMID:15067001 butanal increases expression ISO RGD:731404 6480464 butyraldehyde results in increased expression of PRKCB mRNA CTD PMID:26079696 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of PRKCB mRNA, Cadmium Chloride results in decreased expression of PRKCB protein CTD PMID:25993096 , PMID:27389774 cadmium dichloride multiple interactions EXP 6480464 Quercetin inhibits the reaction [Cadmium Chloride results in decreased expression of PRKCB protein] CTD PMID:27389774 calcium atom multiple interactions ISO RGD:1550017 6480464 Calcium inhibits the reaction [Chlordecone results in increased activity of PRKCB protein], Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 calcium(0) multiple interactions ISO RGD:1550017 6480464 Calcium inhibits the reaction [Chlordecone results in increased activity of PRKCB protein], Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 carbon nanotube decreases expression ISO RGD:1550017 6480464 Nanotubes, Carbon analog results in decreased expression of PRKCB mRNA, Nanotubes, Carbon results in decreased expression of PRKCB mRNA CTD PMID:25554681 chlordecone multiple interactions ISO RGD:1550017 6480464 Calcium inhibits the reaction [Chlordecone results in increased activity of PRKCB protein], Phosphatidylserines promotes the reaction [Chlordecone results in increased activity of PRKCB protein] CTD PMID:1724372 chlordecone increases activity ISO RGD:1550017 6480464 Chlordecone results in increased activity of PRKCB protein CTD PMID:1724372 chloroprene decreases expression ISO RGD:1550017 6480464 Chloroprene results in decreased expression of PRKCB mRNA CTD PMID:23125180 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of PRKCB mRNA CTD PMID:19368821 choline affects expression EXP 6480464 Choline affects the expression of PRKCB mRNA, Choline affects the expression of PRKCB protein CTD PMID:17264169 choline multiple interactions ISO RGD:1550017 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of PRKCB, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PRKCB gene CTD PMID:20938992 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of PRKCB mRNA CTD PMID:22023808 cisplatin affects expression ISO RGD:731404 6480464 Cisplatin affects the expression of PRKCB mRNA CTD PMID:23300844 clobetasol decreases expression ISO RGD:1550017 6480464 Clobetasol results in decreased expression of PRKCB mRNA CTD PMID:27462272 clopidogrel multiple interactions ISO RGD:1550017 6480464 clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of PRKCB mRNA] CTD PMID:19172522 clozapine affects expression EXP 6480464 Clozapine affects the expression of PRKCB protein CTD PMID:15967061 clozapine increases expression EXP 6480464 Clozapine results in increased expression of PRKCB mRNA CTD PMID:15860345 cobalt dichloride multiple interactions EXP 6480464 cobaltous chloride results in increased oxidation of and results in increased activity of PRKCB protein CTD PMID:18375950 cocaine increases expression EXP 6480464 Cocaine results in increased expression of PRKCB mRNA CTD PMID:17898221 cocaine decreases expression ISO RGD:731404 6480464 Cocaine results in decreased expression of PRKCB mRNA CTD PMID:12629581 crocidolite asbestos decreases expression ISO RGD:1550017 6480464 Asbestos, Crocidolite results in decreased expression of PRKCB mRNA CTD PMID:29279043 cycloheximide decreases expression ISO RGD:731404 6480464 Cycloheximide results in decreased expression of PRKCB mRNA CTD PMID:19684285 cycloheximide multiple interactions ISO RGD:731404 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PRKCB mRNA CTD PMID:19684285 cyclosporin A increases expression ISO RGD:1550017 6480464 Cyclosporine results in increased expression of PRKCB protein CTD PMID:22155090 D-glucose multiple interactions EXP 6480464 Glucose results in increased phosphorylation of and results in increased activity of PRKCB protein more ... CTD PMID:19587355 D-glucose increases expression ISO RGD:731404 6480464 Glucose results in increased expression of PRKCB protein, Glucose results in increased expression of PRKCB protein alternative form CTD PMID:16285992 D-glucose increases phosphorylation ISO RGD:731404 6480464 Glucose results in increased phosphorylation of PRKCB protein CTD PMID:22162761 D-glucose multiple interactions ISO RGD:731404 6480464 5 more ... CTD PMID:16285992 , PMID:20578705 D-glucose increases activity ISO RGD:731404 6480464 Glucose results in increased activity of PRKCB protein CTD PMID:20578705 D-mannitol multiple interactions ISO RGD:731404 6480464 Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form], Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein] CTD PMID:16285992 daidzein increases activity EXP 6480464 daidzein results in increased activity of PRKCB protein CTD PMID:16972265 deoxycholic acid multiple interactions ISO RGD:731404 6480464 Aspirin inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] more ... CTD PMID:17644113 deoxycholic acid increases activity ISO RGD:731404 6480464 Deoxycholic Acid results in increased activity of PRKCB protein CTD PMID:7705931 deoxycholic acid increases expression ISO RGD:731404 6480464 Deoxycholic Acid results in increased expression of PRKCB protein CTD PMID:17644113 dexamethasone multiple interactions EXP 6480464 [Bupivacaine co-treated with Tetrodotoxin co-treated with Dexamethasone] results in decreased expression of PRKCB mRNA CTD PMID:22341215 dexmedetomidine multiple interactions EXP 6480464 Dexmedetomidine inhibits the reaction [Lidocaine results in increased expression of PRKCB protein] CTD PMID:30240660 dextran sulfate multiple interactions ISO RGD:1550017 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRKCB mRNA CTD PMID:29950665 diarsenic trioxide affects response to substance ISO RGD:731404 6480464 PRKCB mRNA affects the susceptibility to Arsenic Trioxide CTD PMID:23911876 diarsenic trioxide decreases expression ISO RGD:731404 6480464 Arsenic Trioxide results in decreased expression of PRKCB mRNA CTD PMID:15725085 diarsenic trioxide increases expression ISO RGD:731404 6480464 Arsenic Trioxide results in increased expression of PRKCB mRNA CTD PMID:10673743 , PMID:29442453 diarsenic trioxide multiple interactions ISO RGD:731404 6480464 Tretinoin promotes the reaction [Arsenic Trioxide results in increased expression of PRKCB mRNA] CTD PMID:10673743 dicofol multiple interactions ISO RGD:1550017 6480464 Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein], Phosphatidylserines promotes the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 dicofol increases activity ISO RGD:1550017 6480464 Dicofol results in increased activity of PRKCB protein CTD PMID:1724372 diethyl maleate affects expression ISO RGD:731404 6480464 diethyl maleate affects the expression of PRKCB protein CTD PMID:31958493 diethylstilbestrol increases expression ISO RGD:1550017 6480464 Diethylstilbestrol results in increased expression of PRKCB mRNA CTD PMID:16636312 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of PRKCB mRNA CTD PMID:17005392 diuron increases expression EXP 6480464 Diuron results in increased expression of PRKCB mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:731404 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1550017 6480464 Doxorubicin results in decreased expression of PRKCB mRNA CTD PMID:25896364 doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of PRKCB protein CTD PMID:26318906 elemental selenium decreases expression ISO RGD:731404 6480464 Selenium results in decreased expression of PRKCB mRNA CTD PMID:19244175 entinostat increases expression ISO RGD:731404 6480464 entinostat results in increased expression of PRKCB mRNA CTD PMID:26272509 , PMID:27188386 entinostat multiple interactions ISO RGD:731404 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRKCB mRNA CTD PMID:27188386 ethanol multiple interactions ISO RGD:731404 6480464 [Ethanol results in increased localization of and results in increased activity of PRKCB protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides] CTD PMID:10651808 ethanol affects splicing ISO RGD:1550017 6480464 Ethanol affects the splicing of PRKCB mRNA CTD PMID:30319688 ethanol multiple interactions ISO RGD:1550017 6480464 Ethanol results in increased expression of and results in increased activity of PRKCB protein CTD PMID:22497828 ethanol increases expression EXP 6480464 Ethanol results in increased expression of PRKCB protein CTD PMID:22497828 ethanol multiple interactions EXP 6480464 Losartan inhibits the reaction [Ethanol results in increased expression of PRKCB protein] more ... CTD PMID:22497828 ethyl methanesulfonate decreases expression ISO RGD:731404 6480464 Ethyl Methanesulfonate results in decreased expression of PRKCB mRNA CTD PMID:23649840 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of PRKCB mRNA CTD PMID:18035473 fluorescein 5-isothiocyanate increases expression ISO RGD:731404 6480464 Fluorescein-5-isothiocyanate results in increased expression of PRKCB protein CTD PMID:31958493 fluvoxamine multiple interactions EXP 6480464 [Haloperidol co-treated with Fluvoxamine] affects the expression of PRKCB protein CTD PMID:15967061 folic acid multiple interactions ISO RGD:1550017 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of PRKCB, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PRKCB gene CTD PMID:20938992 formaldehyde decreases expression ISO RGD:731404 6480464 Formaldehyde results in decreased expression of PRKCB mRNA CTD PMID:23649840 furan decreases expression EXP 6480464 furan results in decreased expression of PRKCB mRNA CTD PMID:15120968 furan increases methylation EXP 6480464 furan results in increased methylation of PRKCB gene CTD PMID:22079235 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of PRKCB mRNA CTD PMID:22061828 glucose multiple interactions EXP 6480464 Glucose results in increased phosphorylation of and results in increased activity of PRKCB protein more ... CTD PMID:19587355 glucose increases expression ISO RGD:731404 6480464 Glucose results in increased expression of PRKCB protein, Glucose results in increased expression of PRKCB protein alternative form CTD PMID:16285992 glucose increases phosphorylation ISO RGD:731404 6480464 Glucose results in increased phosphorylation of PRKCB protein CTD PMID:22162761 glucose increases activity ISO RGD:731404 6480464 Glucose results in increased activity of PRKCB protein CTD PMID:20578705 glucose multiple interactions ISO RGD:731404 6480464 5 more ... CTD PMID:16285992 , PMID:20578705 haloperidol multiple interactions EXP 6480464 [Haloperidol co-treated with Fluvoxamine] affects the expression of PRKCB protein CTD PMID:15967061 haloperidol increases expression EXP 6480464 Haloperidol results in increased expression of PRKCB mRNA CTD PMID:15860345 hydrogen peroxide multiple interactions EXP 6480464 Hydrogen Peroxide affects the localization of and results in increased activity of PRKCB protein CTD PMID:12821678 indometacin decreases expression ISO RGD:731404 6480464 Indomethacin results in decreased expression of PRKCB protein alternative form CTD PMID:10702201 indometacin decreases response to substance ISO RGD:731404 6480464 PRKCB protein alternative form results in decreased susceptibility to Indomethacin CTD PMID:10702201 indometacin increases expression ISO RGD:731404 6480464 Indomethacin results in increased expression of PRKCB protein alternative form CTD PMID:10702201 inulin multiple interactions ISO RGD:731404 6480464 PRKCB protein affects the reaction [EGF protein inhibits the reaction [Acetaldehyde results in increased transport of Inulin]] CTD PMID:17991733 irinotecan increases phosphorylation ISO RGD:731404 6480464 Irinotecan metabolite results in increased phosphorylation of PRKCB protein, Irinotecan results in increased phosphorylation of PRKCB protein CTD PMID:15723263 isoprenaline decreases expression ISO RGD:1550017 6480464 Isoproterenol results in decreased expression of PRKCB mRNA CTD PMID:21335049 L-ascorbic acid increases expression ISO RGD:1550017 6480464 Ascorbic Acid results in increased expression of PRKCB mRNA CTD PMID:15305145 L-methionine multiple interactions ISO RGD:1550017 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of PRKCB, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PRKCB gene CTD PMID:20938992 lactacystin multiple interactions ISO RGD:731404 6480464 lactacystin inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] CTD PMID:17644113 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of PRKCB protein CTD PMID:16547843 lead(0) decreases expression EXP 6480464 Lead results in decreased expression of PRKCB protein CTD PMID:16547843 lead(0) affects expression ISO RGD:731404 6480464 Lead affects the expression of PRKCB mRNA CTD PMID:28903495 lead(2+) decreases expression EXP 6480464 Lead results in decreased expression of PRKCB protein CTD PMID:16547843 lead(2+) affects expression ISO RGD:731404 6480464 Lead affects the expression of PRKCB mRNA CTD PMID:28903495 leflunomide increases expression ISO RGD:731404 6480464 leflunomide results in increased expression of PRKCB mRNA CTD PMID:28988120 lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of PRKCB protein CTD PMID:30240660 lidocaine multiple interactions EXP 6480464 Dexmedetomidine inhibits the reaction [Lidocaine results in increased expression of PRKCB protein] CTD PMID:30240660 lipopolysaccharide multiple interactions ISO RGD:1550017 6480464 clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of PRKCB mRNA] CTD PMID:19172522 lithocholic acid increases activity ISO RGD:731404 6480464 Lithocholic Acid results in increased activity of PRKCB protein CTD PMID:7705931 losartan multiple interactions EXP 6480464 Losartan inhibits the reaction [Ethanol results in increased expression of PRKCB protein] CTD PMID:22497828 mercury dibromide decreases expression ISO RGD:731404 6480464 mercuric bromide results in decreased expression of PRKCB mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:731404 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRKCB mRNA CTD PMID:27188386 metformin decreases expression ISO RGD:731404 6480464 Metformin results in decreased expression of PRKCB mRNA, Metformin results in decreased expression of PRKCB protein CTD PMID:15531508 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of PRKCB mRNA CTD PMID:15120968 methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of PRKCB mRNA CTD PMID:15120968 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of PRKCB gene CTD PMID:23303685 methoxychlor decreases expression EXP 6480464 Methoxychlor results in decreased expression of PRKCB mRNA CTD PMID:23303685 methyl methanesulfonate decreases expression ISO RGD:731404 6480464 Methyl Methanesulfonate results in decreased expression of PRKCB mRNA CTD PMID:23649840 methylmercury chloride decreases expression ISO RGD:731404 6480464 methylmercuric chloride results in decreased expression of PRKCB mRNA CTD PMID:28001369 methylseleninic acid increases expression ISO RGD:731404 6480464 methylselenic acid results in increased expression of PRKCB mRNA CTD PMID:18548127 Mezerein multiple interactions ISO RGD:731404 6480464 [bryostatin 1 co-treated with mezerein] results in decreased expression of PRKCB protein, [bryostatin 1 co-treated with mezerein] results in decreased expression of PRKCB protein alternative form CTD PMID:8892972 ML-7 decreases expression EXP 6480464 ML 7 results in decreased expression of PRKCB protein CTD PMID:17272349 morphine multiple interactions ISO RGD:1550017 6480464 HINT1 gene mutant form inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCB protein]], Morphine promotes the reaction [OPRM1 protein binds to PRKCB protein] CTD PMID:18652891 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:1550017 6480464 N more ... CTD PMID:16818790 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:731404 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] CTD PMID:17644113 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PRKCB mRNA CTD PMID:28801915 N-nitrosodiethylamine multiple interactions ISO RGD:1550017 6480464 Diethylnitrosamine results in increased phosphorylation of and results in increased activity of PRKCB protein, MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of PRKCB protein] CTD PMID:17942915 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of PRKCB mRNA CTD PMID:25380136 nickel atom increases expression ISO RGD:731404 6480464 Nickel results in increased expression of PRKCB mRNA CTD PMID:24768652 , PMID:25583101 nickel subsulfide affects expression EXP 6480464 nickel subsulfide affects the expression of PRKCB mRNA CTD PMID:24952340 nicotine affects localization ISO RGD:731404 6480464 Nicotine affects the localization of PRKCB protein CTD PMID:17003101 ochratoxin A increases expression ISO RGD:731404 6480464 ochratoxin A metabolite results in increased expression of PRKCB mRNA, ochratoxin A results in increased expression of PRKCB mRNA CTD PMID:26314263 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of PRKCB mRNA CTD PMID:25729387 p-chloromercuribenzoic acid decreases expression ISO RGD:731404 6480464 p-Chloromercuribenzoic Acid results in decreased expression of PRKCB mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:731404 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRKCB mRNA CTD PMID:27188386 panobinostat multiple interactions ISO RGD:731404 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRKCB mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:731404 6480464 panobinostat results in increased expression of PRKCB mRNA CTD PMID:26272509 paracetamol affects expression ISO RGD:1550017 6480464 Acetaminophen affects the expression of PRKCB mRNA CTD PMID:17562736 paracetamol increases expression ISO RGD:731404 6480464 Acetaminophen results in increased expression of PRKCB mRNA CTD PMID:21420995 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of PRKCB mRNA CTD PMID:15120968 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of PRKCB mRNA CTD PMID:19162173 phenethyl isothiocyanate multiple interactions ISO RGD:731404 6480464 phenethyl isothiocyanate results in decreased phosphorylation of and results in decreased expression of PRKCB protein CTD PMID:26456889 phenylephrine multiple interactions EXP 6480464 Phenylephrine promotes the reaction [RBCK1 protein binds to PRKCB protein], RBCK1 protein inhibits the reaction [Phenylephrine results in increased expression of PRKCB protein] CTD PMID:17121852 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of PRKCB protein CTD PMID:17121852 phenylmercury acetate decreases expression ISO RGD:731404 6480464 Phenylmercuric Acetate results in decreased expression of PRKCB mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:731404 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRKCB mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:731404 6480464 [Ethanol results in increased localization of and results in increased activity of PRKCB protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides] more ... CTD PMID:10651808 more ... phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:731404 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCB protein CTD PMID:24672638 phorbol 13-acetate 12-myristate affects localization ISO RGD:731404 6480464 Tetradecanoylphorbol Acetate affects the localization of PRKCB protein, Tetradecanoylphorbol Acetate affects the localization of PRKCB protein alternative form CTD PMID:15976015 more ... phorbol 13-acetate 12-myristate decreases expression ISO RGD:731404 6480464 Tetradecanoylphorbol Acetate results in decreased expression of PRKCB protein, Tetradecanoylphorbol Acetate results in decreased expression of PRKCB protein modified form CTD PMID:15330761 , PMID:18313772 phorbol 13-acetate 12-myristate increases activity ISO RGD:1550017 6480464 Tetradecanoylphorbol Acetate results in increased activity of PRKCB protein CTD PMID:1724372 phorbol 13-acetate 12-myristate decreases phosphorylation ISO RGD:731404 6480464 Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCB protein CTD PMID:15380616 potassium dichromate increases expression ISO RGD:731404 6480464 Potassium Dichromate results in increased expression of PRKCB protein CTD PMID:23718831 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of PRKCB mRNA CTD PMID:19162173 pterostilbene multiple interactions ISO RGD:1550017 6480464 pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of and results in increased activity of PRKCB protein] CTD PMID:21355597 quercetin decreases expression ISO RGD:1550017 6480464 Quercetin results in decreased expression of PRKCB mRNA CTD PMID:26076811 quercetin decreases expression ISO RGD:731404 6480464 Quercetin results in decreased expression of PRKCB protein CTD PMID:14750173 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Cadmium Chloride results in decreased expression of PRKCB protein] CTD PMID:27389774 quercitrin affects expression ISO RGD:731404 6480464 quercitrin affects the expression of PRKCB mRNA CTD PMID:25193878 resveratrol multiple interactions ISO RGD:731404 6480464 resveratrol inhibits the reaction [Glucose results in increased activity of PRKCB protein], resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCB protein] CTD PMID:20578705 , PMID:24672638 Riluzole multiple interactions ISO RGD:731404 6480464 Riluzole inhibits the reaction [VEGFA protein results in increased phosphorylation of PRKCB protein] CTD PMID:16303979 rotenone decreases expression ISO RGD:731404 6480464 Rotenone results in decreased expression of PRKCB mRNA CTD PMID:29955902 S-butyl-DL-homocysteine (S,R)-sulfoximine decreases activity EXP 6480464 Buthionine Sulfoximine results in decreased activity of PRKCB protein CTD PMID:11118818 sarin increases expression ISO RGD:731404 6480464 Sarin results in increased expression of PRKCB mRNA CTD PMID:19522546 SB 431542 multiple interactions ISO RGD:731404 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 selenium atom decreases expression ISO RGD:731404 6480464 Selenium results in decreased expression of PRKCB mRNA CTD PMID:19244175 serpentine asbestos decreases expression ISO RGD:731404 6480464 Asbestos, Serpentine results in decreased expression of PRKCB mRNA CTD PMID:21148743 silicon dioxide affects expression ISO RGD:731404 6480464 Silicon Dioxide analog affects the expression of PRKCB mRNA CTD PMID:23806026 sodium arsenate increases expression ISO RGD:1550017 6480464 sodium arsenate results in increased expression of PRKCB mRNA CTD PMID:21795629 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of PRKCB protein CTD PMID:24517892 , PMID:30051311 sodium fluoride increases expression ISO RGD:1550017 6480464 Sodium Fluoride results in increased expression of PRKCB mRNA CTD PMID:27862939 sotrastaurin multiple interactions ISO RGD:731404 6480464 sotrastaurin inhibits the reaction [docetaxel results in increased phosphorylation of PRKCB protein] CTD PMID:25634538 sotrastaurin decreases activity ISO RGD:731404 6480464 sotrastaurin results in decreased activity of PRKCB protein CTD PMID:25634538 streptozocin increases phosphorylation EXP 6480464 Streptozocin results in increased phosphorylation of PRKCB protein CTD PMID:16980342 succimer multiple interactions ISO RGD:731404 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of PRKCB mRNA CTD PMID:26378955 sulforaphane increases expression ISO RGD:731404 6480464 sulforafan results in increased expression of PRKCB mRNA CTD PMID:26833863 sunitinib increases expression ISO RGD:731404 6480464 Sunitinib results in increased expression of PRKCB mRNA CTD PMID:31533062 superoxide multiple interactions ISO RGD:731404 6480464 [Ethanol results in increased localization of and results in increased activity of PRKCB protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides] CTD PMID:10651808 T-2 Toxin decreases expression EXP 6480464 T-2 Toxin results in decreased expression of PRKCB mRNA CTD PMID:26141394 tamibarotene increases expression ISO RGD:731404 6480464 tamibarotene results in increased expression of PRKCB mRNA CTD PMID:15498508 tetrachloromethane increases expression ISO RGD:1550017 6480464 Carbon Tetrachloride results in increased expression of PRKCB mRNA CTD PMID:27339419 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of PRKCB mRNA CTD PMID:31150632 tetraphene increases expression ISO RGD:1550017 6480464 benz(a)anthracene results in increased expression of PRKCB mRNA CTD PMID:26377693 tetrodotoxin multiple interactions EXP 6480464 [Bupivacaine co-treated with Tetrodotoxin co-treated with Dexamethasone] results in decreased expression of PRKCB mRNA CTD PMID:22341215 thapsigargin multiple interactions ISO RGD:731404 6480464 Thapsigargin inhibits the reaction [EGF protein affects the localization of PRKCB protein] CTD PMID:17991733 thiabendazole increases expression EXP 6480464 Thiabendazole results in increased expression of PRKCB mRNA CTD PMID:18539377 thiram decreases activity ISO RGD:731404 6480464 Thiram results in decreased activity of PRKCB protein CTD PMID:15998240 titanium dioxide increases expression ISO RGD:1550017 6480464 titanium dioxide results in increased expression of PRKCB mRNA CTD PMID:23557971 titanium dioxide multiple interactions ISO RGD:1550017 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRKCB mRNA CTD PMID:29950665 titanium dioxide decreases expression ISO RGD:1550017 6480464 titanium dioxide results in decreased expression of PRKCB mRNA CTD PMID:27760801 toluene affects expression EXP 6480464 Toluene affects the expression of PRKCB mRNA CTD PMID:21827849 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of PRKCB mRNA CTD PMID:25729387 tributylstannane increases expression ISO RGD:731404 6480464 tributyltin results in increased expression of PRKCB mRNA CTD PMID:26314263 Tributyltin oxide increases expression ISO RGD:731404 6480464 bis(tri-n-butyltin)oxide results in increased expression of PRKCB mRNA CTD PMID:26314263 trichostatin A increases expression ISO RGD:731404 6480464 trichostatin A results in increased expression of PRKCB mRNA CTD PMID:24935251 troglitazone increases expression ISO RGD:1550017 6480464 troglitazone results in increased expression of PRKCB mRNA CTD PMID:28973697 tungsten decreases expression ISO RGD:1550017 6480464 Tungsten results in decreased expression of PRKCB mRNA CTD PMID:30912803 ursodeoxycholic acid increases activity ISO RGD:731404 6480464 Ursodeoxycholic Acid results in increased activity of PRKCB protein CTD PMID:7705931 valproic acid affects expression ISO RGD:731404 6480464 Valproic Acid affects the expression of PRKCB mRNA CTD PMID:25979313 , PMID:29501571 valproic acid affects methylation ISO RGD:731404 6480464 Valproic Acid affects the methylation of PRKCB gene CTD PMID:29501571 valproic acid increases expression ISO RGD:731404 6480464 Valproic Acid results in increased expression of PRKCB mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO RGD:731404 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRKCB mRNA CTD PMID:27188386 vanadium atom decreases expression ISO RGD:731404 6480464 Vanadium results in decreased expression of PRKCB mRNA CTD PMID:19000753 vanadium(0) decreases expression ISO RGD:731404 6480464 Vanadium results in decreased expression of PRKCB mRNA CTD PMID:19000753 vorinostat increases expression ISO RGD:731404 6480464 vorinostat results in increased expression of PRKCB mRNA CTD PMID:26272509 , PMID:27188386 vorinostat multiple interactions ISO RGD:731404 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRKCB mRNA CTD PMID:27188386 zinc atom multiple interactions ISO RGD:1550017 6480464 Zinc promotes the reaction [FCER1A protein affects the localization of PRKCB protein], Zinc promotes the reaction [OPRM1 protein binds to PRKCB protein] CTD PMID:16818790 , PMID:18652891 zinc atom multiple interactions ISO RGD:731404 6480464 PRKCB protein affects the reaction [Tetradecanoylphorbol Acetate affects the localization of Zinc] CTD PMID:16495082 zinc(0) multiple interactions ISO RGD:1550017 6480464 Zinc promotes the reaction [FCER1A protein affects the localization of PRKCB protein], Zinc promotes the reaction [OPRM1 protein binds to PRKCB protein] CTD PMID:16818790 , PMID:18652891 zinc(0) multiple interactions ISO RGD:731404 6480464 PRKCB protein affects the reaction [Tetradecanoylphorbol Acetate affects the localization of Zinc] CTD PMID:16495082
Biological Process adaptive immune response IEA UniProtKB-KW:KW-1064 1600115 GO_REF:0000043 UniProt GO_REF:0000043 apoptotic process IEA UniProtKB-KW:KW-0053 1600115 GO_REF:0000043 UniProt GO_REF:0000043 B cell activation IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 B cell activation ISS UniProtKB:P68404 1600115 GO_REF:0000024 UniProt GO_REF:0000024 B cell activation ISO RGD:1550017 1624291 (MGI:MGI:3626015, PMID:12118249) RGD MGI:MGI:3626015 , PMID:12118249 B cell receptor signaling pathway ISS UniProtKB:P68404 1600115 GO_REF:0000024 UniProt GO_REF:0000024 B cell receptor signaling pathway ISO RGD:1550017 1624291 (MGI:MGI:3626015, PMID:12118249) RGD MGI:MGI:3626015 , PMID:12118249 B cell receptor signaling pathway IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 calcium ion transport ISO RGD:1550017 1624291 (MGI:MGI:2177982, PMID:11880265) RGD MGI:MGI:2177982 , PMID:11880265 calcium ion transport IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular calcium ion homeostasis ISO RGD:1550017 1624291 (MGI:MGI:2177982, PMID:11880265) RGD MGI:MGI:2177982 , PMID:11880265 cellular calcium ion homeostasis IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular response to carbohydrate stimulus ISO RGD:1550017 1624291 (MGI:MGI:3710915, PMID:16585392) RGD MGI:MGI:3710915 , PMID:16585392 cellular response to carbohydrate stimulus IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 dibenzo-p-dioxin metabolic process IEP 5131886 RGD histone H3-T6 phosphorylation ISO RGD:731404 1624291 (PMID:20228790) RGD PMID:20228790 histone H3-T6 phosphorylation IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 histone H3-T6 phosphorylation ISS UniProtKB:P05771 1600115 GO_REF:0000024 UniProt GO_REF:0000024 intracellular signal transduction NAS 631236 RGD intracellular signal transduction IBA FB:FBgn0003744 more ... 13792537 PMID:21873635 GO_Central intracellular signal transduction IEA InterPro:IPR002219 1600115 GO_REF:0000002 InterPro GO_REF:0000002 negative regulation of glucose transmembrane transport IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of glucose transmembrane transport ISS UniProtKB:P68404 1600115 GO_REF:0000024 UniProt GO_REF:0000024 negative regulation of glucose transmembrane transport ISO RGD:1550017 1624291 (MGI:MGI:3624907, PMID:10499500) RGD MGI:MGI:3624907 , PMID:10499500 negative regulation of insulin receptor signaling pathway IDA 8553365 PMID:11714718 UniProt peptidyl-serine phosphorylation IBA FB:FBgn0003744 more ... 13792537 PMID:21873635 GO_Central positive regulation of angiogenesis IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of angiogenesis ISS UniProtKB:P68404 1600115 GO_REF:0000024 UniProt GO_REF:0000024 positive regulation of angiogenesis ISO RGD:1550017 1624291 (MGI:MGI:2157264, PMID:11805327) RGD MGI:MGI:2157264 , PMID:11805327 positive regulation of B cell receptor signaling pathway IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of B cell receptor signaling pathway ISS UniProtKB:P68404 1600115 GO_REF:0000024 UniProt GO_REF:0000024 positive regulation of B cell receptor signaling pathway ISO RGD:1550017 1624291 (MGI:MGI:3700457, PMID:16301747) RGD MGI:MGI:3700457 , PMID:16301747 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of I-kappaB kinase/NF-kappaB signaling ISS UniProtKB:P68404 1600115 GO_REF:0000024 UniProt GO_REF:0000024 positive regulation of I-kappaB kinase/NF-kappaB signaling ISO RGD:1550017 1624291 (MGI:MGI:3626015, PMID:12118249) RGD MGI:MGI:3626015 , PMID:12118249 positive regulation of NF-kappaB transcription factor activity IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of NF-kappaB transcription factor activity ISS UniProtKB:P68404 1600115 GO_REF:0000024 UniProt GO_REF:0000024 positive regulation of NF-kappaB transcription factor activity ISO RGD:1550017 1624291 (MGI:MGI:3700457, PMID:16301747) RGD MGI:MGI:3700457 , PMID:16301747 positive regulation of nucleic acid-templated transcription IEA GO:0030374 1600115 GO_REF:0000108 GOC GO_REF:0000108 positive regulation of odontogenesis of dentin-containing tooth IEP 1625521 RGD positive regulation of vascular endothelial growth factor receptor signaling pathway IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of vascular endothelial growth factor receptor signaling pathway ISS UniProtKB:P68404 1600115 GO_REF:0000024 UniProt GO_REF:0000024 positive regulation of vascular endothelial growth factor receptor signaling pathway ISO RGD:1550017 1624291 (MGI:MGI:2157264, PMID:11805327) RGD MGI:MGI:2157264 , PMID:11805327 presynaptic modulation of chemical synaptic transmission IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 presynaptic modulation of chemical synaptic transmission ISO RGD:1550017 1624291 (MGI:MGI:5141567, PMID:21658591) RGD MGI:MGI:5141567 , PMID:21658591 protein phosphorylation IEA InterPro:IPR000719 more ... 1600115 GO_REF:0000002 InterPro GO_REF:0000002 protein phosphorylation ISO RGD:1550017 1624291 (MGI:MGI:2652984 more ... RGD MGI:MGI:2652984 more ... regulation of dopamine secretion IMP 1625522 RGD regulation of glucose transmembrane transport ISO RGD:731404 1624291 (PMID:25982116) RGD PMID:25982116 regulation of glucose transmembrane transport ISS UniProtKB:P05771 1600115 GO_REF:0000024 UniProt GO_REF:0000024 regulation of growth IMP 1299012 RGD regulation of synaptic vesicle exocytosis IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of synaptic vesicle exocytosis ISO RGD:1550017 1624291 (MGI:MGI:5141567, PMID:21658591) RGD MGI:MGI:5141567 , PMID:21658591 regulation of transcription by RNA polymerase II ISO RGD:731404 1624291 (PMID:20228790) RGD PMID:20228790 regulation of transcription by RNA polymerase II IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of transcription by RNA polymerase II ISS UniProtKB:P05771 1600115 GO_REF:0000024 UniProt GO_REF:0000024 response to drug IMP 1625522 RGD response to ethanol IEP 1625518 RGD response to glucose IEP 1625526 RGD response to hypoxia ISO RGD:1550017 1624291 (MGI:MGI:3847400, PMID:18323529) RGD MGI:MGI:3847400 , PMID:18323529 response to hypoxia NOT ISO RGD:1550017 1624291 (MGI:MGI:3847400, PMID:18323529) RGD MGI:MGI:3847400 , PMID:18323529 response to vitamin D IEP 1625620 RGD Cellular Component brush border membrane IDA 2308883 RGD calyx of Held IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 calyx of Held ISO RGD:1550017 1624291 (MGI:MGI:5141567, PMID:21658591) RGD MGI:MGI:5141567 , PMID:21658591 centrosome IDA 1625528 RGD cytoplasm ISO RGD:731404 1624291 (PMID:15632189) RGD PMID:15632189 cytoplasm IEA UniProtKB-SubCell:SL-0086 1600115 GO_REF:0000044 UniProt GO_REF:0000044 cytoplasm ISO RGD:1550017 1624291 (MGI:MGI:2675925 more ... RGD MGI:MGI:2675925 more ... cytosol IDA 5131655 ; 5131884 RGD cytosol IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytosol ISO RGD:731404 1624291 RGD GO_REF:0000052 membrane ISO RGD:1550017 1624291 (MGI:MGI:3847400, PMID:18323529) RGD MGI:MGI:3847400 , PMID:18323529 membrane IEA UniProtKB-SubCell:SL-0162 1600115 GO_REF:0000044 UniProt GO_REF:0000044 nucleoplasm ISO RGD:731404 1624291 RGD GO_REF:0000052 nucleoplasm IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleus ISO RGD:731404 1624291 (PMID:20228790) RGD PMID:20228790 nucleus IEA UniProtKB-SubCell:SL-0191 1600115 GO_REF:0000044 UniProt GO_REF:0000044 nucleus ISS UniProtKB:P05771 1600115 GO_REF:0000024 UniProt GO_REF:0000024 nucleus ISO RGD:1550017 1624291 (MGI:MGI:2684498, PMID:14613966) RGD MGI:MGI:2684498 , PMID:14613966 plasma membrane ISO RGD:731404 1624291 (PMID:15632189) RGD PMID:15632189 plasma membrane IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 plasma membrane IDA 5131884 RGD presynaptic cytosol ISO RGD:1550017 1624291 (MGI:MGI:5141567, PMID:21658591) RGD MGI:MGI:5141567 , PMID:21658591 spectrin IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 spectrin ISO RGD:1550017 1624291 (MGI:MGI:1346761, PMID:10534118) RGD MGI:MGI:1346761 , PMID:10534118 Molecular Function androgen receptor binding ISO RGD:731404 1624291 (PMID:20228790) RGD PMID:20228790 androgen receptor binding IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 androgen receptor binding ISS UniProtKB:P05771 1600115 GO_REF:0000024 UniProt GO_REF:0000024 ATP binding IEA UniProtKB-KW:KW-0067 1600115 GO_REF:0000043 UniProt GO_REF:0000043 calcium channel regulator activity ISO RGD:1550017 1624291 (MGI:MGI:2177982, PMID:11880265) RGD MGI:MGI:2177982 , PMID:11880265 calcium channel regulator activity IEA UniProtKB:P68404 , ensembl:ENSMUSP000000700191600115 GO_REF:0000107 Ensembl GO_REF:0000107 calcium-dependent protein kinase C activity IEA EC:2.7.11.13 1600115 GO_REF:0000003 UniProt GO_REF:0000003 chromatin binding ISO RGD:731404 1624291 (PMID:20228790) RGD PMID:20228790 chromatin binding IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 chromatin binding ISS UniProtKB:P05771 1600115 GO_REF:0000024 UniProt GO_REF:0000024 histone binding ISO RGD:731404 1624291 (PMID:20228790) RGD PMID:20228790 histone binding IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 histone binding ISS UniProtKB:P05771 1600115 GO_REF:0000024 UniProt GO_REF:0000024 histone kinase activity (H3-T6 specific) ISO RGD:731404 1624291 (PMID:20228790) RGD PMID:20228790 histone kinase activity (H3-T6 specific) IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 histone kinase activity (H3-T6 specific) ISS UniProtKB:P05771 1600115 GO_REF:0000024 UniProt GO_REF:0000024 nuclear receptor transcription coactivator activity ISO RGD:731404 1624291 (PMID:20228790) RGD PMID:20228790 nuclear receptor transcription coactivator activity IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 nuclear receptor transcription coactivator activity ISS UniProtKB:P05771 1600115 GO_REF:0000024 UniProt GO_REF:0000024 protein binding IPI UniProtKB:Q8WV44-2 8553520 PMID:17893151 IntAct protein binding ISO RGD:731404 1624291 UniProtKB:O60341 more ... RGD PMID:18162466 more ... protein binding ISO RGD:1550017 1624291 PR:Q5NCC3 more ... RGD MGI:MGI:3696512 more ... protein binding IPI UniProtKB:Q62920 632670 PMID:8940095 IntAct protein binding IPI UniProtKB:P18052 8554305 PMID:7537734 IntAct protein kinase C activity IDA 631236 RGD protein kinase C activity ISO RGD:731404 1624291 (PMID:25982116) RGD PMID:25982116 protein kinase C activity ISO RGD:1550017 1624291 (MGI:MGI:2652984 more ... RGD MGI:MGI:2652984 more ... protein kinase C binding ISO RGD:731404 1624291 UniProtKB:Q16512 (PMID:20228790) RGD PMID:20228790 protein kinase C binding IEA UniProtKB:P05771 , ensembl:ENSP000004961291600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein serine/threonine kinase activity ISO RGD:1550017 1624291 (MGI:MGI:5538470, PMID:23775122) RGD MGI:MGI:5538470 , PMID:23775122 protein serine/threonine kinase activity IBA CGD:CAL0000198853 more ... 13792537 PMID:21873635 GO_Central protein serine/threonine kinase activity ISO RGD:731404 1624291 (PMID:12391145) RGD PMID:12391145 zinc ion binding IEA InterPro:IPR014375 1600115 GO_REF:0000002 InterPro GO_REF:0000002
Gene-Chemical Interaction Annotations
