Bmp2 (bone morphogenetic protein 2) - Rat Genome Database

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Gene: Bmp2 (bone morphogenetic protein 2) Rattus norvegicus
Analyze
Symbol: Bmp2
Name: bone morphogenetic protein 2
RGD ID: 2211
Description: Enables growth factor activity; identical protein binding activity; and protein domain specific binding activity. Involved in several processes, including BMP signaling pathway; cellular response to mechanical stimulus; and response to retinoic acid. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm; extracellular space; and vesicle. Part of protein-containing complex. Human ortholog(s) of this gene implicated in bone disease (multiple); hemochromatosis type 1; otosclerosis; prostate cancer; and tooth agenesis. Orthologous to human BMP2 (bone morphogenetic protein 2); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; basal cell carcinoma pathway; Hedgehog signaling pathway; INTERACTS WITH (20S)-ginsenoside Rg3; (R)-mevalonic acid; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BMP-2; BMP-2A; bone morphogenetic protein 2A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23120,812,660 - 120,822,579 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3120,812,882 - 120,821,397 (+)Ensembl
Rnor_6.03126,335,963 - 126,346,771 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3126,335,863 - 126,346,318 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03132,822,005 - 132,832,789 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43121,372,692 - 121,381,236 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13121,278,264 - 121,286,806 (+)NCBI
Celera3119,596,986 - 119,605,358 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(20S)-ginsenoside Rg3  (EXP)
(R)-adrenaline  (ISO)
(R)-mevalonic acid  (EXP,ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (EXP)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-hydroxypropanoic acid  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
2-trans,6-trans-farnesyl diphosphate  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-methoxypsoralen  (ISO)
6-propyl-2-thiouracil  (EXP)
acetaldehyde  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
aluminium oxide  (ISO)
ammonium chloride  (EXP)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (EXP)
atorvastatin calcium  (ISO)
aucubin  (ISO)
azadirachtin A  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzoates  (ISO)
beta-D-glucosamine  (EXP)
bexarotene  (EXP)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A5  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
Calcimycin  (ISO)
calciol  (ISO)
calcitriol  (EXP,ISO)
carbon nanotube  (ISO)
cerivastatin  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
dibutyl phthalate  (ISO)
dichromium trioxide  (ISO)
dioxygen  (EXP,ISO)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
farnesyl diphosphate  (ISO)
fipronil  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (EXP,ISO)
furan  (EXP)
gadolinium trichloride  (EXP)
gamma-aminobutyric acid  (EXP)
genistein  (EXP,ISO)
ginsenoside Rb1  (EXP)
glucose  (ISO)
glycerol 2-phosphate  (EXP,ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
glyphosate  (EXP)
hesperidin  (EXP)
icariin  (EXP,ISO)
imperatorin  (ISO)
kaempferol  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (EXP,ISO)
L-ascorbic acid 2-phosphate  (ISO)
lead diacetate  (EXP,ISO)
letrozole  (ISO)
lipopolysaccharide  (EXP,ISO)
losartan  (EXP)
LY294002  (ISO)
maneb  (ISO)
menaquinone  (EXP)
menaquinone-4  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mevastatin  (ISO)
mitomycin C  (ISO)
N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide  (EXP)
N-acetyl-1,4-benzoquinone imine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
naringin  (EXP,ISO)
nickel atom  (EXP)
nickel sulfate  (EXP)
octreotide  (ISO)
oxaliplatin  (EXP)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pasireotide  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phylloquinone  (EXP)
pirinixic acid  (ISO)
progesterone  (EXP,ISO)
quercetin  (EXP,ISO)
rac-lactic acid  (ISO)
ranitidine  (EXP)
Rebamipide  (EXP)
resveratrol  (ISO)
Salidroside  (ISO)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP,ISO)
Tanshinone I  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (EXP,ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vincristine  (ISO)
vorinostat  (ISO)
warfarin  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (ISO)
aortic valve development  (IEA,ISO)
atrioventricular canal morphogenesis  (IEA,ISO)
atrioventricular valve morphogenesis  (IEA,ISO)
BMP signaling pathway  (IBA,IDA,ISO,ISS)
BMP signaling pathway involved in heart development  (IEA,ISO)
BMP signaling pathway involved in heart induction  (ISO,ISS)
bone development  (ISO)
bone mineralization  (ISO)
bone mineralization involved in bone maturation  (ISO,ISS)
branching involved in ureteric bud morphogenesis  (IEA,ISO)
cardiac atrium formation  (IEA,ISO)
cardiac epithelial to mesenchymal transition  (IEA,ISO)
cardiac jelly development  (IEA,ISO)
cardiac muscle cell differentiation  (IEA,ISO)
cardiac muscle tissue morphogenesis  (IEA,ISO)
cardiocyte differentiation  (ISO)
cell fate commitment  (IEA,ISO)
cellular response to BMP stimulus  (IEP,ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to mechanical stimulus  (IEP)
cellular response to organic cyclic compound  (IEA,ISO)
chondrocyte differentiation  (IEA,ISO)
corticotropin hormone secreting cell differentiation  (IEA,ISO)
embryonic heart tube anterior/posterior pattern specification  (IEA,ISO)
endocardial cushion formation  (IEA,ISO)
endocardial cushion morphogenesis  (ISO)
epithelial to mesenchymal transition  (ISO,ISS)
gene expression  (ISO)
heart development  (ISO)
in utero embryonic development  (IEA,ISO)
inflammatory response  (IEA,ISO)
inner ear development  (IEA,ISO)
mesenchymal cell differentiation  (ISO,ISS)
mesenchymal cell proliferation involved in ureteric bud development  (IEA,ISO)
mesenchyme development  (ISO)
negative regulation of aldosterone biosynthetic process  (IEA,ISO)
negative regulation of calcium-independent cell-cell adhesion  (IEA,ISO)
negative regulation of canonical Wnt signaling pathway  (IEA,ISO)
negative regulation of cardiac muscle cell differentiation  (ISO,ISS)
negative regulation of cell cycle  (ISO,ISS)
negative regulation of cell population proliferation  (ISO)
negative regulation of cortisol biosynthetic process  (IEA,ISO)
negative regulation of gene expression  (IEA,ISO)
negative regulation of insulin-like growth factor receptor signaling pathway  (IEA,ISO)
negative regulation of MAP kinase activity  (IEA,ISO)
negative regulation of muscle cell differentiation  (ISO)
negative regulation of smooth muscle cell proliferation  (IEA,ISO)
negative regulation of steroid biosynthetic process  (ISO)
negative regulation of transcription by RNA polymerase II  (IBA,ISO,ISS)
negative regulation of transcription, DNA-templated  (ISO,ISS)
negative regulation of transforming growth factor beta receptor signaling pathway  (IEA,ISO)
negative regulation of Wnt signaling pathway involved in heart development  (ISO,ISS)
Notch signaling pathway  (IEA,ISO)
odontogenesis of dentin-containing tooth  (IEA,ISO)
osteoblast differentiation  (IEA,ISO)
ovulation cycle  (IEP)
pathway-restricted SMAD protein phosphorylation  (IEA,ISO)
pericardium development  (IEA,ISO)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of astrocyte differentiation  (IEA,ISO)
positive regulation of bone mineralization  (ISO,ISS)
positive regulation of cartilage development  (IEA,ISO)
positive regulation of cell differentiation  (ISO)
positive regulation of cell migration  (IEA,ISO)
positive regulation of DNA-binding transcription factor activity  (IEA,ISO)
positive regulation of endothelial cell proliferation  (ISO,ISS)
positive regulation of epithelial to mesenchymal transition  (IEA,ISO)
positive regulation of ERK1 and ERK2 cascade  (IEA,ISO)
positive regulation of extracellular matrix constituent secretion  (IEA,ISO)
positive regulation of fat cell differentiation  (IEA,ISO)
positive regulation of gene expression  (IEA,ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of neurogenesis  (IDA)
positive regulation of neuron differentiation  (IEA,ISO)
positive regulation of odontogenesis  (IEA,ISO)
positive regulation of ossification  (ISO)
positive regulation of osteoblast differentiation  (ISO,ISS)
positive regulation of osteoblast proliferation  (IEA,ISO)
positive regulation of p38MAPK cascade  (IEA,ISO)
positive regulation of pathway-restricted SMAD protein phosphorylation  (IBA,ISO,ISS)
positive regulation of peroxisome proliferator activated receptor signaling pathway  (IEA,ISO)
positive regulation of phosphatase activity  (IEA,ISO)
positive regulation of pri-miRNA transcription by RNA polymerase II  (IEA,ISO)
positive regulation of protein binding  (IEA,ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein serine/threonine kinase activity  (IEA)
positive regulation of SMAD protein signal transduction  (IEA,ISO)
positive regulation of transcription by RNA polymerase II  (IDA,ISO,ISS)
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus  (IEA,ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of Wnt signaling pathway  (ISO)
positive regulation of Wnt signaling pathway by BMP signaling pathway  (IEA,ISO)
protein destabilization  (IEA,ISO)
protein phosphorylation  (ISO)
proteoglycan metabolic process  (IEA,ISO)
regulation of odontogenesis of dentin-containing tooth  (IEA,ISO)
regulation of transcription, DNA-templated  (ISO)
response to bacterium  (IEA,ISO)
response to hypoxia  (IEA,ISO)
response to mechanical stimulus  (IEP)
response to retinoic acid  (IEP)
SMAD protein signal transduction  (IBA,ISO,ISS)
telencephalon development  (ISO)
telencephalon regionalization  (IEA,ISO)
thyroid-stimulating hormone-secreting cell differentiation  (IEA,ISO)

Cellular Component

References

References - curated
1. Abe N, etal., Biochem Biophys Res Commun 2002 Sep 27;297(3):523-7.
2. Chalazonitis A, etal., J Neurosci 2004 Apr 28;24(17):4266-82.
3. Doak SH, etal., Cancer Genet Cytogenet. 2007 Jul 15;176(2):161-5.
4. Enokiya Y, etal., Bull Tokyo Dent Coll. 2010;51(3):129-37.
5. Erickson DM, etal., J Orthop Res. 1997 May;15(3):371-80.
6. Erickson GF, etal., J Endocrinol. 2004 Aug;182(2):203-17.
7. Feng JQ, etal., Biochim Biophys Acta 1994 Jun 21;1218(2):221-4.
8. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. Gazit D, etal., Mol Endocrinol. 1993 Feb;7(2):189-98.
10. GOA data from the GO Consortium
11. Horvath LG, etal., Prostate. 2004 May 15;59(3):234-42.
12. Kaplan FS, etal., Calcif Tissue Int 1990 Aug;47(2):117-25.
13. Kubota K, etal., Bone 2002 Oct;31(4):465-71.
14. Lee MH, etal., J Biol Chem 2003 Sep 5;278(36):34387-94. Epub 2003 Jun 18.
15. Li ZL, etal., Zhonghua Nan Ke Xue. 2006 Feb;12(2):126-8, 132.
16. MGD data from the GO Consortium
17. Mu Y, etal., Genet Mol Res. 2012 Nov 28;11(4):4110-20. doi: 10.4238/2012.September.25.5.
18. Nahar NN, etal., J Bone Miner Metab. 2008;26(5):514-9. Epub 2008 Aug 30.
19. NCBI rat LocusLink and RefSeq merged data July 26, 2002
20. Ngo TQ, etal., J Histochem Cytochem. 2006 Aug;54(8):945-54. Epub 2006 May 1.
21. OMIM Disease Annotation Pipeline
22. Pipeline to import KEGG annotations from KEGG into RGD
23. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
24. RGD automated data pipeline
25. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
26. RGD automated import pipeline for gene-chemical interactions
27. Sandner B, etal., Stem Cell Res. 2013 Sep;11(2):758-71. doi: 10.1016/j.scr.2013.05.003. Epub 2013 May 16.
28. Sato M, etal., J Bone Miner Res. 1999 Jul;14(7):1084-95.
29. Schrauwen I, etal., J Bone Miner Res. 2008 Apr;23(4):507-16.
30. Shah NM, etal., Cell. 1996 May 3;85(3):331-43.
31. Sipe JB, etal., Bone. 2004 Dec;35(6):1316-22.
32. Sweatt A, etal., J Thromb Haemost. 2003 Jan;1(1):178-85.
33. Takahashi H, etal., Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L450-8. Epub 2005 Dec 16.
34. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
35. Valdes AM, etal., Arthritis Rheum. 2004 Aug;50(8):2497-507.
36. Xiong DH, etal., J Bone Miner Res. 2006 Nov;21(11):1678-95.
Additional References at PubMed
PMID:1468569   PMID:3201241   PMID:7811286   PMID:7848824   PMID:8653785   PMID:8769660   PMID:8898212   PMID:9187146   PMID:9213002   PMID:9244299   PMID:9463347   PMID:9585504  
PMID:9693150   PMID:9769173   PMID:9786991   PMID:10391928   PMID:10486560   PMID:10684250   PMID:11502704   PMID:11719201   PMID:12151307   PMID:12421925   PMID:12782312   PMID:14623234  
PMID:14627707   PMID:15110716   PMID:15150273   PMID:15175325   PMID:15254224   PMID:15322112   PMID:15358784   PMID:15383550   PMID:15525533   PMID:15565649   PMID:15657444   PMID:15671031  
PMID:15695507   PMID:15820682   PMID:15851600   PMID:15882580   PMID:15886483   PMID:15925496   PMID:15975920   PMID:16049014   PMID:16099986   PMID:16109715   PMID:16194878   PMID:16243309  
PMID:16314491   PMID:16433617   PMID:16604073   PMID:16935278   PMID:16996588   PMID:17001659   PMID:17158861   PMID:17171790   PMID:17202865   PMID:17244894   PMID:17415742   PMID:17472960  
PMID:17473173   PMID:17953369   PMID:17992660   PMID:18070548   PMID:18184661   PMID:18295562   PMID:18313401   PMID:18326817   PMID:18335997   PMID:18380969   PMID:18436533   PMID:18545679  
PMID:18600149   PMID:18832104   PMID:19103752   PMID:19208758   PMID:19213727   PMID:19584291   PMID:19617624   PMID:19664780   PMID:19669850   PMID:19736317   PMID:19852960   PMID:20019778  
PMID:20042692   PMID:20048761   PMID:20065295   PMID:20576608   PMID:20675382   PMID:20843790   PMID:20882582   PMID:20886619   PMID:20890042   PMID:20926379   PMID:20936960   PMID:20939479  
PMID:21043834   PMID:21049555   PMID:21145505   PMID:21157119   PMID:21311046   PMID:21324897   PMID:21350216   PMID:21415150   PMID:21520255   PMID:21590708   PMID:21592969   PMID:21624478  
PMID:21636885   PMID:21737358   PMID:21795542   PMID:21873793   PMID:22227436   PMID:22363399   PMID:22450430   PMID:22508088   PMID:22540193   PMID:22556155   PMID:22579779   PMID:22674456  
PMID:22705305   PMID:22829700   PMID:22861354   PMID:22994418   PMID:23010719   PMID:23012479   PMID:23088504   PMID:23238867   PMID:23359400   PMID:23447035   PMID:23620751   PMID:23632743  
PMID:23821199   PMID:23822814   PMID:24111806   PMID:24167632   PMID:24306516   PMID:24406215   PMID:24416413   PMID:24464097   PMID:24648278   PMID:24682653   PMID:24866243   PMID:25100727  
PMID:25218476   PMID:25446167   PMID:25659106   PMID:25677945   PMID:25725805   PMID:25823394   PMID:25896232   PMID:26308798   PMID:26345843   PMID:26352281   PMID:26404484   PMID:26763079  
PMID:26772960   PMID:26797522   PMID:26931551   PMID:27178636   PMID:27477499   PMID:27771997   PMID:27885436   PMID:28124060   PMID:28256809   PMID:28457943   PMID:28595186   PMID:28642034  
PMID:29785051   PMID:29850574   PMID:30700748   PMID:30937700   PMID:31002144   PMID:31432121   PMID:31694396   PMID:31737960   PMID:31746352   PMID:32131378  


Genomics

Comparative Map Data
Bmp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23120,812,660 - 120,822,579 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3120,812,882 - 120,821,397 (+)Ensembl
Rnor_6.03126,335,963 - 126,346,771 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3126,335,863 - 126,346,318 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03132,822,005 - 132,832,789 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43121,372,692 - 121,381,236 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13121,278,264 - 121,286,806 (+)NCBI
Celera3119,596,986 - 119,605,358 (+)NCBICelera
Cytogenetic Map3q36NCBI
BMP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl206,767,686 - 6,780,246 (+)EnsemblGRCh38hg38GRCh38
GRCh38206,767,686 - 6,780,246 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37206,748,333 - 6,760,893 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36206,696,745 - 6,708,910 (+)NCBINCBI36hg18NCBI36
Build 34206,697,206 - 6,707,769NCBI
Celera206,819,903 - 6,832,070 (+)NCBI
Cytogenetic Map20p12.3NCBI
HuRef206,705,637 - 6,717,811 (+)NCBIHuRef
CHM1_1206,748,804 - 6,760,970 (+)NCBICHM1_1
Bmp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392133,394,079 - 133,404,816 (+)NCBIGRCm39mm39
GRCm39 Ensembl2133,394,079 - 133,404,805 (+)Ensembl
GRCm382133,552,159 - 133,562,896 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2133,552,159 - 133,562,885 (+)EnsemblGRCm38mm10GRCm38
MGSCv372133,378,935 - 133,388,621 (+)NCBIGRCm37mm9NCBIm37
MGSCv362133,244,640 - 133,254,326 (+)NCBImm8
Celera2134,774,971 - 134,784,597 (+)NCBICelera
Cytogenetic Map2F2NCBI
cM Map265.21NCBI
Bmp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541517,048,030 - 17,060,181 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541517,048,374 - 17,058,172 (+)NCBIChiLan1.0ChiLan1.0
BMP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1206,546,173 - 6,558,627 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl206,546,173 - 6,558,610 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0206,765,161 - 6,777,728 (+)NCBIMhudiblu_PPA_v0panPan3
BMP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12415,199,667 - 15,211,509 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2415,200,291 - 15,212,217 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2415,022,880 - 15,034,779 (-)NCBI
ROS_Cfam_1.02415,603,929 - 15,615,829 (-)NCBI
UMICH_Zoey_3.12415,210,353 - 15,222,261 (-)NCBI
UNSW_CanFamBas_1.02415,320,936 - 15,332,831 (-)NCBI
UU_Cfam_GSD_1.02415,650,158 - 15,662,056 (-)NCBI
Bmp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640163,997,168 - 164,008,273 (-)NCBI
SpeTri2.0NW_00493648512,428,765 - 12,439,570 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1715,749,835 - 15,761,215 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11715,750,487 - 15,762,982 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21717,052,609 - 17,064,132 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BMP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1231,349,394 - 31,361,227 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl231,348,808 - 31,360,901 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607113,190,629 - 13,202,875 (+)NCBIVero_WHO_p1.0
Bmp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247417,706,205 - 7,717,677 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH131457  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23120,821,085 - 120,821,279 (+)MAPPERmRatBN7.2
Rnor_6.03126,344,388 - 126,344,581NCBIRnor6.0
Rnor_5.03132,830,406 - 132,830,599UniSTSRnor5.0
RGSC_v3.43121,380,922 - 121,381,115UniSTSRGSC3.4
Celera3119,605,044 - 119,605,237UniSTS
RH 3.4 Map31052.5UniSTS
Cytogenetic Map3q36UniSTS
UniSTS:464654  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23120,820,845 - 120,820,970 (+)MAPPERmRatBN7.2
Rnor_6.03126,344,148 - 126,344,272NCBIRnor6.0
Rnor_5.03132,830,166 - 132,830,290UniSTSRnor5.0
RGSC_v3.43121,380,682 - 121,380,806UniSTSRGSC3.4
Celera3119,604,804 - 119,604,928UniSTS
Cytogenetic Map3q36UniSTS
UniSTS:496639  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23120,820,783 - 120,821,024 (+)MAPPERmRatBN7.2
Rnor_6.03126,344,086 - 126,344,326NCBIRnor6.0
Rnor_5.03132,830,104 - 132,830,344UniSTSRnor5.0
RGSC_v3.43121,380,620 - 121,380,860UniSTSRGSC3.4
Celera3119,604,742 - 119,604,982UniSTS
Cytogenetic Map3q36UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1581546Pur13Proteinuria QTL 132.930.0335total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:101
Count of miRNA genes:85
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000028904, ENSRNOT00000073728
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 10 2 2 2 4 10
Low 2 32 49 39 13 39 7 9 74 30 24 11 7
Below cutoff 1 6 6 1 2 1 6 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000028904   ⟹   ENSRNOP00000028904
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3126,335,863 - 126,346,318 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108290   ⟹   ENSRNOP00000081600
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3120,812,882 - 120,821,397 (+)Ensembl
RefSeq Acc Id: NM_017178   ⟹   NP_058874
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23120,812,687 - 120,821,400 (+)NCBI
Rnor_6.03126,336,185 - 126,344,702 (+)NCBI
Rnor_5.03132,822,005 - 132,832,789 (+)NCBI
RGSC_v3.43121,372,692 - 121,381,236 (+)RGD
Celera3119,596,986 - 119,605,358 (+)RGD
Sequence:
RefSeq Acc Id: XM_039104435   ⟹   XP_038960363
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23120,812,660 - 120,822,579 (+)NCBI
Protein Sequences
Protein RefSeqs NP_058874 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960363 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA81088 (Get FASTA)   NCBI Sequence Viewer  
  EDL80282 (Get FASTA)   NCBI Sequence Viewer  
  EDL80283 (Get FASTA)   NCBI Sequence Viewer  
  P49001 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058874   ⟸   NM_017178
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: ENSRNOP00000028904   ⟸   ENSRNOT00000028904
RefSeq Acc Id: XP_038960363   ⟸   XM_039104435
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000081600   ⟸   ENSRNOT00000108290
Protein Domains
TGF_BETA_2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692461
Promoter ID:EPDNEW_R2984
Type:single initiation site
Name:Bmp2_1
Description:bone morphogenetic protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03126,335,794 - 126,335,854EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2211 AgrOrtholog
Ensembl Genes ENSRNOG00000021276 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000071010 Ensembl
Ensembl Protein ENSRNOP00000028904 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028904 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF-b_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGFb_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29373 UniProtKB/Swiss-Prot
NCBI Gene 29373 ENTREZGENE
PANTHER PTHR11848 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bmp2 PhenoGen
PROSITE TGF_BETA_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TGFB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC217827
UniProt BMP2_RAT UniProtKB/Swiss-Prot
  G3V8W4_RAT UniProtKB/TrEMBL
  P49001 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Bmp2  bone morphogenetic protein 2      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in spleen 69777
gene_function growth factor 631753
gene_homology has 90% identity to human protein 69777
gene_process induces ectopic bone formation 631753
gene_product member of the transforming growth factor beta superfamily 69777
gene_transcript transcript has 3 exons 69777
gene_transcript 11kb 69777