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Gene: Mbl2 (mannose binding lectin 2) Rattus norvegicus
Symbol: Mbl2
Name: mannose binding lectin 2
Description: Exhibits several functions, including monosaccharide binding activity; phosphatidylinositol-4-phosphate binding activity; and protein self-association. Involved in positive regulation of complement activation; positive regulation of protein processing; and protein homotrimerization. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); bacterial infectious disease (multiple); fungal infectious disease (multiple); lung disease (multiple); and vasculitis (multiple). Orthologous to human MBL2 (mannose binding lectin 2); PARTICIPATES IN lectin complement pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
Also known as: Ab2-001; Ab2-011; mannan-binding protein; mannose binding lectin 2 (protein C); mannose-binding lectin (protein C) 2; mannose-binding protein C; mannose-binding protein C (liver); MBP-C; RA-reactive factor P28A subunit; ra-reactive factor polysaccharide-binding component p28A; raRF p28A; RARF/P28A
Homo sapiens (human) : MBL2 (mannose binding lectin 2)  HGNC  Alliance
Mus musculus (house mouse) : Mbl2 (mannose-binding lectin (protein C) 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mbl2 (mannose binding lectin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MBL2 (mannose binding lectin 2)
Canis lupus familiaris (dog) : MBL2 (mannose binding lectin 2)
Sus scrofa (pig) : MBL2 (mannose binding lectin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01248,435,069 - 248,442,669 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01255,681,084 - 255,688,683 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,978,931 - 233,983,824 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11234,140,682 - 234,147,846 (+)NCBI
Celera1225,160,772 - 225,165,665 (+)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mbl2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 67380
Created: 2001-06-01
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.