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Structural polymorphism of the mannose-binding lectin 2 (MBL2 ) gene in HCV-infected patients with a serological marker for thyroid autoimmunity.

Authors: Melo, F M  Vasconcelos, L R S  Silva, B S  Moura, P  Cavalcanti, M S M  Pereira, L M M B  Lacerda, H R 
Citation: Melo FM, etal., Int J Immunogenet. 2009 Dec;36(6):377-81. doi: 10.1111/j.1744-313X.2009.00871.x. Epub 2009 Aug 24.
Pubmed: (View Article at PubMed) PMID:19703233
DOI: Full-text: DOI:10.1111/j.1744-313X.2009.00871.x

We studied the association of the mannose-binding lectin-2 (MBL2) polymorphism with anti-thyroid antibodies (ATA) in hepatitis C virus (HCV)-infected Brazilian patients (n = 162) and 124 healthy volunteers screened for ATA. Our results showed that patients with ATA had higher frequency of genotype 00 than controls. MBL may play a role as disease modifier in HCV infection.

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RGD Object Information
RGD ID: 14696815
Created: 2019-07-29
Species: All species
Last Modified: 2019-07-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.