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Gene: Mbl2 (mannose-binding lectin (protein C) 2) Mus musculus
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Symbol: Mbl2
Name: mannose-binding lectin (protein C) 2
Description: Predicted to have several functions, including calcium-dependent protein binding activity; monosaccharide binding activity; and phosphatidylinositol-4-phosphate binding activity. Involved in defense response to other organism and positive regulation of phagocytosis. Localizes to extracellular space. Is expressed in embryo. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hypersensitivity disease (multiple); bacterial infectious disease (multiple); fungal infectious disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MBL2 (mannose binding lectin 2); PARTICIPATES IN lectin complement pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: L-MBP; mannan-binding protein; mannose binding lectin (C); mannose binding lectin, liver (C); mannose-binding protein C; MBL; MBL-C; MBP-C; RA-reactive factor P28A subunit; RARF/P28A
Orthologs:
Homo sapiens (human) : MBL2 (mannose binding lectin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mbl2 (mannose binding lectin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mbl2 (mannose binding lectin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MBL2 (mannose binding lectin 2)
Canis lupus familiaris (dog) : MBL2 (mannose binding lectin 2)
Sus scrofa (pig) : MBL2 (mannose binding lectin 2)
Chlorocebus sabaeus (African green monkey) : MBL2 (mannose binding lectin 2)
Heterocephalus glaber (naked mole-rat) : Mbl2 (mannose binding lectin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1930,232,942 - 30,239,687 (+)EnsemblGRCm38mm10GRCm38
GRCm381930,232,906 - 30,239,687 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371930,307,447 - 30,314,172 (+)NCBIGRCm37mm9NCBIm37
MGSCv361930,298,954 - 30,305,679 (+)NCBImm8
Celera1931,010,980 - 31,017,684 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1925.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mbl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731472
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.