Uchl3 (ubiquitin C-terminal hydrolase L3) - Rat Genome Database

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Gene: Uchl3 (ubiquitin C-terminal hydrolase L3) Rattus norvegicus
Analyze
Symbol: Uchl3
Name: ubiquitin C-terminal hydrolase L3
RGD ID: 1561196
Description: Predicted to enable cysteine-type deubiquitinase activity and ubiquitin binding activity. Predicted to be involved in cellular response to insulin stimulus; positive regulation of fat cell differentiation; and protein catabolic process. Predicted to act upstream of or within adult walking behavior; eating behavior; and retina development in camera-type eye. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human UCHL3 (ubiquitin C-terminal hydrolase L3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC498560; RGD1561196; similar to ubiqutin carboxyl-terminal hydrolase l3; ubiquitin carboxyl-terminal esterase L3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin thioesterase L3; UCH-L3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Uchl3-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81584,888,847 - 84,942,095 (+)NCBIGRCr8
mRatBN7.21578,485,304 - 78,527,355 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3161,856,958 - 161,857,835 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1578,485,315 - 78,527,355 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1582,496,066 - 82,538,090 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01583,572,627 - 83,614,651 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01580,493,216 - 80,535,240 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01586,153,624 - 86,198,127 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1586,153,628 - 86,198,127 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01589,919,728 - 89,964,227 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41585,628,490 - 85,670,420 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1577,676,770 - 77,718,591 (+)NCBICelera
Cytogenetic Map15q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzatropine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDT  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
fenthion  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glucose  (ISO)
graphite  (EXP)
inulin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lead(II) chloride  (ISO)
Mesaconitine  (EXP)
methapyrilene  (EXP)
methidathion  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (EXP)
N-nitrosodiethylamine  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phlorizin  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
sarin  (ISO)
SB 431542  (ISO)
senecionine  (ISO)
Senkirkine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
thalidomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
undecane  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (ISO)
nucleoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia. Kurihara LJ, etal., Hum Mol Genet 2001 Sep 1;10(18):1963-70.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9521656   PMID:15632090   PMID:19154770   PMID:19837878   PMID:21052544   PMID:21762696   PMID:23376485   PMID:26609154  


Genomics

Comparative Map Data
Uchl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81584,888,847 - 84,942,095 (+)NCBIGRCr8
mRatBN7.21578,485,304 - 78,527,355 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3161,856,958 - 161,857,835 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1578,485,315 - 78,527,355 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1582,496,066 - 82,538,090 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01583,572,627 - 83,614,651 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01580,493,216 - 80,535,240 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01586,153,624 - 86,198,127 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1586,153,628 - 86,198,127 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01589,919,728 - 89,964,227 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41585,628,490 - 85,670,420 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1577,676,770 - 77,718,591 (+)NCBICelera
Cytogenetic Map15q21NCBI
UCHL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381375,549,502 - 75,606,020 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1375,549,483 - 75,606,020 (+)EnsemblGRCh38hg38GRCh38
GRCh371376,123,638 - 76,180,156 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361375,021,928 - 75,078,070 (+)NCBINCBI36Build 36hg18NCBI36
Build 341375,021,927 - 75,078,067NCBI
Celera1357,021,803 - 57,077,943 (+)NCBICelera
Cytogenetic Map13q22.2NCBI
HuRef1356,821,075 - 56,877,308 (+)NCBIHuRef
CHM1_11376,091,356 - 76,147,870 (+)NCBICHM1_1
T2T-CHM13v2.01374,773,163 - 74,829,671 (+)NCBIT2T-CHM13v2.0
Uchl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914101,891,387 - 101,933,561 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14101,891,403 - 101,933,561 (+)EnsemblGRCm39 Ensembl
GRCm3814101,653,892 - 101,696,125 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14101,653,967 - 101,696,125 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714102,053,184 - 102,095,342 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614100,540,246 - 100,582,053 (+)NCBIMGSCv36mm8
Celera14100,293,249 - 100,335,409 (+)NCBICelera
Cytogenetic Map14E2.3NCBI
cM Map1450.9NCBI
Uchl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540431,414,208 - 31,464,968 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540431,414,076 - 31,465,205 (-)NCBIChiLan1.0ChiLan1.0
UCHL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21477,127,881 - 77,183,967 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11375,725,673 - 75,781,714 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01356,776,436 - 56,832,539 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11375,549,305 - 75,878,805 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1375,549,647 - 75,878,673 (+)Ensemblpanpan1.1panPan2
UCHL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12229,348,962 - 29,397,944 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2229,348,706 - 29,407,965 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2229,151,524 - 29,258,782 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02229,625,506 - 29,732,716 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2229,684,385 - 29,736,169 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12229,276,538 - 29,383,650 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02229,320,217 - 29,427,245 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02229,388,463 - 29,495,905 (+)NCBIUU_Cfam_GSD_1.0
Uchl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945130,107,193 - 130,163,980 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365115,522,965 - 5,581,334 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365115,524,425 - 5,581,156 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UCHL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1147,828,421 - 47,887,629 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11147,829,037 - 47,885,800 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21152,436,220 - 52,477,054 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UCHL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl354,647,590 - 54,706,497 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604610,791,194 - 10,849,805 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uchl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475124,882,705 - 24,940,105 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475124,882,580 - 24,940,301 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Uchl3
116 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:8
Count of miRNA genes:8
Interacting mature miRNAs:8
Transcripts:ENSRNOT00000028960
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)155559608991365858Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)155559608995018120Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
1331724Bp223Blood pressure QTL 2233.53715arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)157369051895018228Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)157369051899794247Rat
70182BpQTLcluster12Blood pressure QTL cluster 123.53arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)157369065795018120Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1575788062101769107Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
1581555Eae19Experimental allergic encephalomyelitis QTL 194.7nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)157630609990088744Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat

Markers in Region
Uchl4  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.43163,941,308 - 163,942,074UniSTSRGSC3.4
Celera3161,050,303 - 161,051,069UniSTS
Cytogenetic Map3q42UniSTS
Cytogenetic Map15q21UniSTS
BM390056  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21578,494,992 - 78,495,193 (-)MAPPERmRatBN7.2
mRatBN7.21578,494,992 - 78,495,193 (+)MAPPERmRatBN7.2
Rnor_6.01586,163,284 - 86,163,484NCBIRnor6.0
Rnor_6.03171,124,878 - 171,125,078NCBIRnor6.0
Rnor_5.03177,191,047 - 177,191,247UniSTSRnor5.0
Rnor_5.01589,929,384 - 89,929,584UniSTSRnor5.0
RGSC_v3.41585,638,146 - 85,638,346UniSTSRGSC3.4
Celera1577,686,426 - 77,686,626UniSTS
RH 3.4 Map15503.1UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map3q42UniSTS
PMC85452P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.43163,941,362 - 163,942,072UniSTSRGSC3.4
Celera3161,050,357 - 161,051,067UniSTS
Cytogenetic Map3q42UniSTS
Cytogenetic Map15q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 6 12 12 2 12 62 16 34
Low 1 37 45 29 19 29 8 13 19 19 12 11 8
Below cutoff 2 9 16 7 13 7 2 2 45 15 26 5 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001110165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB043959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000012842   ⟹   ENSRNOP00000012842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1578,485,315 - 78,527,349 (+)Ensembl
Rnor_6.0 Ensembl1586,153,628 - 86,198,127 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000028960   ⟹   ENSRNOP00000029819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1578,496,608 - 78,527,355 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104271   ⟹   ENSRNOP00000091247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1578,485,336 - 78,527,355 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112431   ⟹   ENSRNOP00000092785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1578,485,336 - 78,527,355 (+)Ensembl
RefSeq Acc Id: NM_001110165   ⟹   NP_001103635
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,078 - 84,942,095 (+)NCBI
mRatBN7.21578,485,336 - 78,527,355 (+)NCBI
Rnor_6.01586,153,628 - 86,198,127 (+)NCBI
Rnor_5.01589,919,728 - 89,964,227 (+)NCBI
RGSC_v3.41585,628,490 - 85,670,420 (+)RGD
Celera1577,676,770 - 77,718,591 (+)RGD
Sequence:
RefSeq Acc Id: XM_039093599   ⟹   XP_038949527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,899,862 - 84,942,093 (+)NCBI
mRatBN7.21578,485,304 - 78,527,353 (+)NCBI
RefSeq Acc Id: XM_063274569   ⟹   XP_063130639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,899,862 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274570   ⟹   XP_063130640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274571   ⟹   XP_063130641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,098 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274572   ⟹   XP_063130642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274573   ⟹   XP_063130643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,888,847 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274574   ⟹   XP_063130644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274575   ⟹   XP_063130645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,102 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274576   ⟹   XP_063130646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,060 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274577   ⟹   XP_063130647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,045 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274578   ⟹   XP_063130648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,899,862 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274579   ⟹   XP_063130649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,045 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274580   ⟹   XP_063130650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,059 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274581   ⟹   XP_063130651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274582   ⟹   XP_063130652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274583   ⟹   XP_063130653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,063 - 84,942,093 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001103635 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949527 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130639 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130640 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130641 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130642 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130643 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130644 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130645 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130646 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130647 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130648 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130649 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130650 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130651 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130652 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130653 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB47136 (Get FASTA)   NCBI Sequence Viewer  
  EDM02439 (Get FASTA)   NCBI Sequence Viewer  
  EDM02440 (Get FASTA)   NCBI Sequence Viewer  
  EDM02441 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012842
  ENSRNOP00000012842.5
  ENSRNOP00000029819.5
  ENSRNOP00000091247
  ENSRNOP00000091247.1
  ENSRNOP00000092785.1
  ENSRNOP00000095149.1
  ENSRNOP00055009983
  ENSRNOP00060020545
  ENSRNOP00065008141
GenBank Protein Q91Y78 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001103635   ⟸   NM_001110165
- UniProtKB: Q91Y78 (UniProtKB/Swiss-Prot),   A6KKZ2 (UniProtKB/TrEMBL),   A6HU77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012842   ⟸   ENSRNOT00000012842
RefSeq Acc Id: XP_038949527   ⟸   XM_039093599
- Peptide Label: isoform X15
- UniProtKB: A0A8I6AE48 (UniProtKB/TrEMBL),   A6HU77 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000092785   ⟸   ENSRNOT00000112431
RefSeq Acc Id: ENSRNOP00000029819   ⟸   ENSRNOT00000028960
RefSeq Acc Id: ENSRNOP00000091247   ⟸   ENSRNOT00000104271
RefSeq Acc Id: XP_063130643   ⟸   XM_063274573
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063130639   ⟸   XM_063274569
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130648   ⟸   XM_063274578
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063130647   ⟸   XM_063274577
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063130649   ⟸   XM_063274579
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063130642   ⟸   XM_063274572
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063130644   ⟸   XM_063274574
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063130640   ⟸   XM_063274570
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063130652   ⟸   XM_063274582
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063130651   ⟸   XM_063274581
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063130650   ⟸   XM_063274580
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063130646   ⟸   XM_063274576
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063130653   ⟸   XM_063274583
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063130641   ⟸   XM_063274571
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063130645   ⟸   XM_063274575
- Peptide Label: isoform X7
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91Y78-F1-model_v2 AlphaFold Q91Y78 1-230 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699863
Promoter ID:EPDNEW_R10386
Type:initiation region
Name:Uchl3_1
Description:ubiquitin C-terminal hydrolase L3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01586,153,626 - 86,153,686EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561196 AgrOrtholog
BioCyc Gene G2FUF-12748 BioCyc
Ensembl Genes ENSRNOG00000009530 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000065893 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055007508 UniProtKB/Swiss-Prot
  ENSRNOG00060014959 UniProtKB/Swiss-Prot
  ENSRNOG00065007054 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012842 ENTREZGENE
  ENSRNOT00000012842.7 UniProtKB/TrEMBL
  ENSRNOT00000028960.6 UniProtKB/TrEMBL
  ENSRNOT00000104271.1 UniProtKB/TrEMBL
  ENSRNOT00000112431.1 UniProtKB/TrEMBL
  ENSRNOT00000113306.1 UniProtKB/TrEMBL
  ENSRNOT00055012563 UniProtKB/Swiss-Prot
  ENSRNOT00060025720 UniProtKB/Swiss-Prot
  ENSRNOT00065011136 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.532.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C12_UCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C12_UCH_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:498560 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 498560 ENTREZGENE
PANTHER PTHR10589 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_C12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Uchl3 PhenoGen
PRINTS UBCTHYDRLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE UCH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009530 RatGTEx
  ENSRNOG00000065893 RatGTEx
  ENSRNOG00055007508 RatGTEx
  ENSRNOG00060014959 RatGTEx
  ENSRNOG00065007054 RatGTEx
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AE48 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJY6_RAT UniProtKB/TrEMBL
  A0A8J8Y1V7_RAT UniProtKB/TrEMBL
  A6HU77 ENTREZGENE, UniProtKB/TrEMBL
  A6KKZ2 ENTREZGENE, UniProtKB/TrEMBL
  D4ABI6_RAT UniProtKB/TrEMBL
  Q91Y78 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary F1LM67 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Uchl3  ubiquitin C-terminal hydrolase L3  Uchl3  ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-02 Uchl3  ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)  RGD1561196  similar to ubiqutin carboxyl-terminal hydrolase l3   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561196  similar to ubiqutin carboxyl-terminal hydrolase l3   RGD1561196_predicted  similar to ubiqutin carboxyl-terminal hydrolase l3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561196_predicted  similar to ubiqutin carboxyl-terminal hydrolase l3 (predicted)  LOC498560  similar to ubiqutin carboxyl-terminal hydrolase l3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498560  similar to ubiqutin carboxyl-terminal hydrolase l3      Symbol and Name status set to provisional 70820 PROVISIONAL