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Gene: Cldn5 (claudin 5) Rattus norvegicus
Symbol: Cldn5
Name: claudin 5
Description: Predicted to have identical protein binding activity. Involved in myelination and response to ethanol. Localizes to the Schmidt-Lanterman incisure; lateral plasma membrane; and paranode region of axon. Predicted to colocalize with the cortical actin cytoskeleton. Biomarker of middle cerebral artery infarction. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CLDN5 (claudin 5); PARTICIPATES IN hepatitis C pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: claudin-5; MGC95240
Homo sapiens (human) : CLDN5 (claudin 5)  HGNC  Alliance
Mus musculus (house mouse) : Cldn5 (claudin 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cldn5 (claudin 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CLDN5 (claudin 5)
Canis lupus familiaris (dog) : CLDN5 (claudin 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cldn5 (claudin 5)
Sus scrofa (pig) : CLDN5 (claudin 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01186,356,292 - 86,357,718 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01189,458,258 - 89,459,684 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1180,993,136 - 80,994,562 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cldn5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68431
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.