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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68431
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cldn5
Name: claudin 5
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cldn5decreases expressionEXP 6480464CTDLead results in decreased expression of CLDN5 proteinPMID:20970449
Cldn5multiple interactionsEXP 6480464CTD[malaoxon co-treated with Lead] results in decreased expression of CLDN5 protein; [Malathion co-treated with Lead] results in decreased expression of CLDN5 proteinPMID:20970449
Cldn5multiple interactionsISOCldn5 (Mus musculus)6480464CTD[lead acetate results in increased abundance of Lead] which results in decreased expression of CLDN5 proteinPMID:31730887
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