Lhfpl6 (LHFPL tetraspan subfamily member 6) - Rat Genome Database

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Gene: Lhfpl6 (LHFPL tetraspan subfamily member 6) Rattus norvegicus
Analyze
Symbol: Lhfpl6
Name: LHFPL tetraspan subfamily member 6
RGD ID: 1560177
Description: Predicted to be active in membrane. Orthologous to human LHFPL6 (LHFPL tetraspan subfamily member 6); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Lhfp; lipoma HMGIC fusion partner; MGC109397; RGD1560177; similar to RIKEN cDNA 2810489O06
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82139,276,810 - 139,474,740 (+)NCBIGRCr8
mRatBN7.22137,126,485 - 137,324,442 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2137,126,509 - 137,324,443 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2143,703,670 - 143,908,731 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02141,815,746 - 142,020,807 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02136,447,500 - 136,652,570 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02142,262,236 - 142,461,980 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2142,262,236 - 142,461,980 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02161,947,947 - 162,146,115 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42141,974,792 - 142,183,203 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2131,623,723 - 131,820,297 (+)NCBICelera
Cytogenetic Map2q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
cannabidiol  (ISO)
captan  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
cytarabine  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
fenamidone  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
fonofos  (ISO)
genistein  (EXP)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
isotretinoin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
pentanal  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
Soman  (EXP)
sunitinib  (ISO)
terbufos  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Lhfpl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82139,276,810 - 139,474,740 (+)NCBIGRCr8
mRatBN7.22137,126,485 - 137,324,442 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2137,126,509 - 137,324,443 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2143,703,670 - 143,908,731 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02141,815,746 - 142,020,807 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02136,447,500 - 136,652,570 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02142,262,236 - 142,461,980 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2142,262,236 - 142,461,980 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02161,947,947 - 162,146,115 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42141,974,792 - 142,183,203 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2131,623,723 - 131,820,297 (+)NCBICelera
Cytogenetic Map2q26NCBI
LHFPL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381339,342,892 - 39,603,193 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1339,209,116 - 39,603,528 (-)EnsemblGRCh38hg38GRCh38
GRCh371339,917,029 - 40,177,330 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361338,815,029 - 39,075,356 (-)NCBINCBI36Build 36hg18NCBI36
Build 341338,815,029 - 39,075,201NCBI
Celera1320,971,004 - 21,230,116 (-)NCBICelera
Cytogenetic Map13q13.3-q14.11NCBI
HuRef1320,717,038 - 20,976,465 (-)NCBIHuRef
CHM1_11339,884,864 - 40,144,901 (-)NCBICHM1_1
T2T-CHM13v2.01338,562,524 - 38,821,662 (-)NCBIT2T-CHM13v2.0
Lhfpl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39352,948,968 - 53,169,100 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl352,948,949 - 53,169,100 (+)EnsemblGRCm39 Ensembl
GRCm38353,041,547 - 53,261,679 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl353,041,528 - 53,261,679 (+)EnsemblGRCm38mm10GRCm38
MGSCv37352,845,469 - 53,065,601 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36353,129,476 - 53,349,608 (+)NCBIMGSCv36mm8
Celera352,770,052 - 52,986,552 (+)NCBICelera
Cytogenetic Map3CNCBI
cM Map324.17NCBI
Lhfpl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554316,745,848 - 6,976,647 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554316,745,745 - 6,977,662 (+)NCBIChiLan1.0ChiLan1.0
LHFPL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21438,874,719 - 39,133,596 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11329,979,578 - 30,238,405 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01320,560,260 - 20,819,037 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11339,147,003 - 39,405,533 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1339,182,518 - 39,403,746 (-)Ensemblpanpan1.1panPan2
LHFPL6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1251,567,799 - 1,805,030 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl251,567,335 - 1,804,535 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha251,664,664 - 1,901,788 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0251,665,939 - 1,903,037 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl251,665,962 - 1,903,032 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1251,567,933 - 1,804,444 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0251,560,904 - 1,797,968 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0251,627,749 - 1,867,664 (+)NCBIUU_Cfam_GSD_1.0
Lhfpl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945162,629,806 - 162,860,113 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365656,115,682 - 6,344,244 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365656,113,917 - 6,344,153 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LHFPL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1114,319,428 - 14,560,181 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11114,319,420 - 14,576,130 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21114,546,880 - 14,559,891 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LHFPL6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1317,724,768 - 17,981,405 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605726,265,229 - 26,554,843 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lhfpl6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624748140,383 - 407,294 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624748139,378 - 409,093 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lhfpl6
1016 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:469
Count of miRNA genes:246
Interacting mature miRNAs:304
Transcripts:ENSRNOT00000019057
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2102803808147803808Rat
5135226Leukc2Leukocyte quantity QTL 2eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)2118111229149559726Rat
738007Anxrr7Anxiety related response QTL 74.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2118189491163189491Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2104559726149559726Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
1358360Sradr2Stress Responsive Adrenal Weight QTL 210.24adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)2129164097152195315Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1354594Despr10Despair related QTL 100.00000249locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)2114654253159654253Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
1549841Bp256Blood pressure QTL 2560.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2137219876142323610Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527143657569Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527143657569Rat
1582257Gluco21Glucose level QTL 213.10.0035blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2118111229157142209Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1581552Pur12Proteinuria QTL 125.190.0009urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)2112103657148076632Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2127447387143657569Rat
1598862Glom9Glomerulus QTL 93.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)292337601137337601Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)276539322150540526Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)278665616143657569Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
12879833Cm84Cardiac mass QTL 840.001heart right ventricle mass (VT:0007033)heart weight to body weight ratio (CMO:0000074)2137219876142323610Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1598863Cm65Cardiac mass QTL 652.3heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)292337601137337601Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
12879831Cm82Cardiac mass QTL 820.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2137219876142323610Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
12879832Cm83Cardiac mass QTL 830.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2137219876142323610Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
12879835Kidm60Kidney mass QTL 600.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2137219876142323610Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
12879830Bw178Body weight QTL 1780.001body mass (VT:0001259)body weight (CMO:0000012)2137219876142323610Rat
12879834Am1Aortic mass QTL 10.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2137219876142323610Rat

Markers in Region
D2Rat220  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22137,154,180 - 137,154,326 (+)MAPPERmRatBN7.2
Rnor_6.02142,289,751 - 142,289,896NCBIRnor6.0
Rnor_5.02161,975,462 - 161,975,607UniSTSRnor5.0
RGSC_v3.42142,003,999 - 142,004,145RGDRGSC3.4
RGSC_v3.42142,004,000 - 142,004,145UniSTSRGSC3.4
RGSC_v3.12141,953,962 - 141,954,108RGD
Celera2131,651,439 - 131,651,584UniSTS
SHRSP x BN Map257.1798RGD
SHRSP x BN Map257.1798UniSTS
Cytogenetic Map2q26UniSTS
D2Chm33  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22137,219,876 - 137,220,085 (+)MAPPERmRatBN7.2
Rnor_6.02142,355,464 - 142,355,672NCBIRnor6.0
Rnor_5.02162,041,036 - 162,041,244UniSTSRnor5.0
RGSC_v3.42142,068,645 - 142,068,853UniSTSRGSC3.4
Celera2131,717,182 - 131,717,390UniSTS
Cytogenetic Map2q26UniSTS
RH141719  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22137,155,101 - 137,155,281 (+)MAPPERmRatBN7.2
Rnor_6.02142,290,672 - 142,290,851NCBIRnor6.0
Rnor_5.02161,976,383 - 161,976,562UniSTSRnor5.0
RGSC_v3.42142,004,921 - 142,005,100UniSTSRGSC3.4
Celera2131,652,360 - 131,652,539UniSTS
RH 3.4 Map2855.6UniSTS
Cytogenetic Map2q26UniSTS
BI281007  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22137,324,112 - 137,324,271 (+)MAPPERmRatBN7.2
Rnor_6.02142,461,651 - 142,461,809NCBIRnor6.0
Rnor_5.02162,145,786 - 162,145,944UniSTSRnor5.0
RGSC_v3.42142,182,874 - 142,183,032UniSTSRGSC3.4
Celera2131,819,968 - 131,820,126UniSTS
RH 3.4 Map2850.8UniSTS
Cytogenetic Map2q26UniSTS
RH143913  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22137,128,284 - 137,128,436 (+)MAPPERmRatBN7.2
Rnor_6.02142,264,036 - 142,264,187NCBIRnor6.0
Rnor_5.02161,949,747 - 161,949,898UniSTSRnor5.0
RGSC_v3.42141,976,592 - 141,976,743UniSTSRGSC3.4
Celera2131,625,523 - 131,625,674UniSTS
RH 3.4 Map2850.8UniSTS
Cytogenetic Map2q26UniSTS
AA956142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22137,324,242 - 137,324,423 (+)MAPPERmRatBN7.2
Rnor_6.02142,461,781 - 142,461,961NCBIRnor6.0
Rnor_5.02162,145,916 - 162,146,096UniSTSRnor5.0
RGSC_v3.42142,183,004 - 142,183,184UniSTSRGSC3.4
Celera2131,820,098 - 131,820,278UniSTS
RH 3.4 Map2849.2UniSTS
Cytogenetic Map2q26UniSTS
AU046805  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22137,219,799 - 137,220,097 (+)MAPPERmRatBN7.2
Rnor_6.02142,355,387 - 142,355,684NCBIRnor6.0
Rnor_5.02162,040,959 - 162,041,256UniSTSRnor5.0
RGSC_v3.42142,068,568 - 142,068,865UniSTSRGSC3.4
Celera2131,717,105 - 131,717,402UniSTS
Cytogenetic Map2q26UniSTS
BI281007  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22137,324,111 - 137,324,292 (+)MAPPERmRatBN7.2
Rnor_6.02142,461,650 - 142,461,830NCBIRnor6.0
Rnor_5.02162,145,785 - 162,145,965UniSTSRnor5.0
RGSC_v3.42142,182,873 - 142,183,053UniSTSRGSC3.4
Celera2131,819,967 - 131,820,147UniSTS
RH 3.4 Map2850.8UniSTS
Cytogenetic Map2q26UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 41 10 10 10 2 3 74 25 35 11 2
Low 1 2 47 31 19 31 6 8 10 6 6
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000019057   ⟹   ENSRNOP00000019057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2137,126,509 - 137,324,413 (+)Ensembl
Rnor_6.0 Ensembl2142,262,236 - 142,461,980 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117418   ⟹   ENSRNOP00000092096
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2137,126,581 - 137,324,443 (+)Ensembl
RefSeq Acc Id: NM_001109183   ⟹   NP_001102653
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82139,276,810 - 139,474,740 (+)NCBI
mRatBN7.22137,126,485 - 137,324,442 (+)NCBI
Rnor_6.02142,262,236 - 142,461,980 (+)NCBI
Rnor_5.02161,947,947 - 162,146,115 (+)NCBI
RGSC_v3.42141,974,792 - 142,183,203 (+)RGD
Celera2131,623,723 - 131,820,297 (+)RGD
Sequence:
RefSeq Acc Id: NP_001102653   ⟸   NM_001109183
- Peptide Label: precursor
- UniProtKB: Q5BJS2 (UniProtKB/Swiss-Prot),   A6JV93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000019057   ⟸   ENSRNOT00000019057
RefSeq Acc Id: ENSRNOP00000092096   ⟸   ENSRNOT00000117418

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BJS2-F1-model_v2 AlphaFold Q5BJS2 1-200 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691322
Promoter ID:EPDNEW_R1847
Type:initiation region
Name:Lhfpl6_1
Description:LHFPL tetraspan subfamily member 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02142,262,251 - 142,262,311EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560177 AgrOrtholog
BioCyc Gene G2FUF-53102 BioCyc
Ensembl Genes ENSRNOG00000014153 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055023916 UniProtKB/Swiss-Prot
  ENSRNOG00060000842 UniProtKB/Swiss-Prot
  ENSRNOG00065023974 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019057.5 UniProtKB/TrEMBL
  ENSRNOT00000117418 ENTREZGENE
  ENSRNOT00000117418.1 UniProtKB/Swiss-Prot
  ENSRNOT00055041040 UniProtKB/Swiss-Prot
  ENSRNOT00060001039 UniProtKB/Swiss-Prot
  ENSRNOT00065041122 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.140.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro LHFPL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:499615 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 499615 ENTREZGENE
PANTHER LHFPL TETRASPAN SUBFAMILY MEMBER 6 PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12489 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam L_HMGIC_fpl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lhfpl6 PhenoGen
RatGTEx ENSRNOG00000014153 RatGTEx
  ENSRNOG00055023916 RatGTEx
  ENSRNOG00060000842 RatGTEx
  ENSRNOG00065023974 RatGTEx
UniProt A0A8L2QAJ8_RAT UniProtKB/TrEMBL
  A6JV93 ENTREZGENE, UniProtKB/TrEMBL
  LHPL6_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-05 Lhfpl6  LHFPL tetraspan subfamily member 6  Lhfp  lipoma HMGIC fusion partner  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-09-18 Lhfp  lipoma HMGIC fusion partner  RGD1560177_predicted  similar to RIKEN cDNA 2810489O06 (predicted)  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1560177_predicted  similar to RIKEN cDNA 2810489O06 (predicted)  MGC109397  similar to RIKEN cDNA 2810489O06  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 MGC109397  similar to RIKEN cDNA 2810489O06      Symbol and Name status set to provisional 70820 PROVISIONAL