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Gene: Inpp5d (inositol polyphosphate-5-phosphatase D) Rattus norvegicus
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Symbol: Inpp5d
Name: inositol polyphosphate-5-phosphatase D
Description: Exhibits inositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in several processes, including negative regulation of B cell proliferation; negative regulation of bone resorption; and regulation of hemopoiesis. Localizes to the actin filament; cortical cytoskeleton; and cytosol. Colocalizes with the plasma membrane. Orthologous to human INPP5D (inositol polyphosphate-5-phosphatase D); PARTICIPATES IN erythropoietin signaling pathway; Fc epsilon receptor mediated signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: inositol polyphosphate-5-phosphatase; Inositol polyphosphate-5-phosphatase 145 kDa; Inositol polyphosphate-5-phosphatase, 145 kDa; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1; phosphatidylinositol-4,5-bisphosphate 5-phosphatase; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SH2 domain-containing inositol-5'-phosphatase 1; SHIP-1
Orthologs:
Homo sapiens (human) : INPP5D (inositol polyphosphate-5-phosphatase D)  HGNC  Alliance
Mus musculus (house mouse) : Inpp5d (inositol polyphosphate-5-phosphatase D)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Inpp5d (inositol polyphosphate-5-phosphatase D)
Pan paniscus (bonobo/pygmy chimpanzee) : INPP5D (inositol polyphosphate-5-phosphatase D)
Canis lupus familiaris (dog) : INPP5D (inositol polyphosphate-5-phosphatase D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Inpp5d (inositol polyphosphate-5-phosphatase D)
Sus scrofa (pig) : INPP5D (inositol polyphosphate-5-phosphatase D)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0994,745,220 - 94,850,778 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0994,464,380 - 94,569,984 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,576,742 - 86,682,240 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1986,760,159 - 86,865,657 (+)NCBI
Celera985,697,060 - 85,801,952 (+)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Inpp5d
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2914
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.