Esrrg (estrogen-related receptor gamma)

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Gene: Esrrg (estrogen-related receptor gamma) Rattus norvegicus

Analyze

Symbol:

Esrrg

Name:

estrogen-related receptor gamma

RGD ID:

1303236

Description:

Predicted to enable several functions, including AF-2 domain binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and estrogen response element binding activity. Predicted to be involved in intracellular steroid hormone receptor signaling pathway; positive regulation of cold-induced thermogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ESRRG (estrogen related receptor gamma); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

errg; estrogen receptor-related protein 3; nuclear receptor subfamily 3 group B member 3

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ESRRG (estrogen related receptor gamma)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Esrrg (estrogen-related receptor gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Esrrg (estrogen related receptor gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ESRRG (estrogen related receptor gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ESRRG (estrogen related receptor gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Esrrg (estrogen related receptor gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ESRRG (estrogen related receptor gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ESRRG (estrogen related receptor gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Esrrg (estrogen related receptor gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ESRRB (estrogen related receptor beta)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	ESRRG (estrogen related receptor gamma)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Esrrg (estrogen-related receptor gamma)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	esrrgb (estrogen-related receptor gamma b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	esrrga (estrogen-related receptor gamma a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ERR	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	esrrb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	esrrg	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	99,167,656 - 99,788,016 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	99,564,669 - 99,783,397 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	101,739,863 - 102,301,030 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	103,128,963 - 103,690,094 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	100,325,840 - 100,886,886 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	106,063,799 - 106,683,353 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	106,463,368 - 106,683,436 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	110,713,353 - 111,328,942 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	103,794,661 - 104,405,301 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	103,983,703 - 104,594,344 (+)	NCBI
Celera	13	98,720,991 - 99,277,811 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Fetal Growth Retardation (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

Loeys-Dietz syndrome 4 (ISO)

parathyroid carcinoma (ISO)

primary ovarian insufficiency (ISO)

Usher syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (ISO)

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-di-tert-butylphenol (ISO)

2-arachidonoylglycerol (ISO)

2-methylcholine (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

4-chloro-m-cresol (ISO)

4-ethylphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

4-isopropylphenol (ISO)

4-tert-butylphenol (ISO)

4-tert-Octylphenol (ISO)

5,6,7,8-tetrahydro-2-naphthol (ISO)

8-Br-cAMP (ISO)

afimoxifene (EXP,ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arachidonyl-2'-chloroethylamide (EXP,ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

Benzo[ghi]perylene (ISO)

Benzyl parahydroxybenzoate (ISO)

biochanin A (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

Butylparaben (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

daidzein (ISO)

diarsenic trioxide (ISO)

diethylstilbestrol (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

Ethyl salicylate (ISO)

ethylparaben (ISO)

fenthion (ISO)

folic acid (ISO)

furan (EXP)

genistein (ISO)

glyphosate (EXP)

GSK 4716 (ISO)

inulin (ISO)

lithium chloride (ISO)

LY294002 (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

methyl salicylate (ISO)

methylmercury chloride (ISO)

methylparaben (ISO)

nickel atom (ISO)

O-methyleugenol (ISO)

ochratoxin A (ISO)

p-tert-Amylphenol (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenol red (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

propylparaben (ISO)

SB 431542 (ISO)

serpentine asbestos (ISO)

sodium arsenite (ISO)

tamoxifen (ISO)

tauroursodeoxycholic acid (ISO)

testosterone enanthate (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

zalcitabine (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular steroid hormone receptor signaling pathway (IBA)

positive regulation of cold-induced thermogenesis (ISO,ISS)

positive regulation of DNA-templated transcription (ISO)

positive regulation of transcription by RNA polymerase II (ISO,ISS)

regulation of DNA-templated transcription (IEA,ISO,ISS)

regulation of transcription by RNA polymerase II (IBA)

retinoic acid receptor signaling pathway (IEA)

steroid hormone mediated signaling pathway (IEA)

Cellular Component

nucleus (IEA)

Molecular Function

AF-2 domain binding (ISS)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

estrogen response element binding (IBA,ISO)

identical protein binding (ISO)

nuclear receptor activity (IBA,IEA)

nuclear steroid receptor activity (IEA)

protein binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (ISO)

sequence-specific DNA binding (IEA)

sequence-specific double-stranded DNA binding (ISO)

steroid binding (IEA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Estrogen receptor-related receptor gamma has an exceptionally broad specificity of DNA sequence recognition.	Razzaque MA, etal., Gene 2004 Oct 13;340(2):275-82.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis.	Villena JA, etal., Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1418-23. doi: 10.1073/pnas.0607696104. Epub 2007 Jan 17.

Additional References at PubMed

PMID:10428842	PMID:12715898	PMID:15149736	PMID:17079227	PMID:21911493	PMID:23404793	PMID:23836911	PMID:26404484	PMID:36481985

Genomics

Comparative Map Data

Esrrg
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	99,167,656 - 99,788,016 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	99,564,669 - 99,783,397 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	101,739,863 - 102,301,030 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	103,128,963 - 103,690,094 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	100,325,840 - 100,886,886 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	106,063,799 - 106,683,353 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	106,463,368 - 106,683,436 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	110,713,353 - 111,328,942 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	103,794,661 - 104,405,301 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	103,983,703 - 104,594,344 (+)	NCBI
Celera	13	98,720,991 - 99,277,811 (+)	NCBI		Celera
Cytogenetic Map	13	q26	NCBI

ESRRG
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	216,503,246 - 217,137,702 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	216,503,246 - 217,137,755 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	216,676,588 - 217,311,044 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	214,743,211 - 215,329,599 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	213,064,982 - 213,651,371	NCBI
Celera	1	189,900,435 - 190,535,016 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI
HuRef	1	187,351,966 - 187,986,618 (-)	NCBI		HuRef
CHM1_1	1	217,949,719 - 218,583,931 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	215,743,580 - 216,378,774 (-)	NCBI		T2T-CHM13v2.0

Esrrg
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	187,340,707 - 187,947,082 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	187,340,988 - 187,947,082 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	187,608,510 - 188,214,885 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	187,608,791 - 188,214,885 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	189,821,738 - 190,038,763 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	189,698,647 - 189,915,672 (+)	NCBI		MGSCv36	mm8
Celera	1	194,923,141 - 195,141,266 (+)	NCBI		Celera
Cytogenetic Map	1	H5- H6	NCBI
cM Map	1	91.83	NCBI

Esrrg
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	1,560,485 - 1,788,250 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	1,260,240 - 1,784,652 (+)	NCBI	ChiLan1.0	ChiLan1.0

ESRRG
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	1	32,266,717 - 32,859,746 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	192,074,260 - 192,667,610 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	196,929,197 - 197,508,064 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	196,929,197 - 197,153,195 (-)	Ensembl	panpan1.1		panPan2

ESRRG
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	11,825,055 - 12,439,143 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	11,823,520 - 12,256,028 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	11,862,256 - 12,476,998 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	11,851,190 - 12,466,509 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	11,849,973 - 12,421,362 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	11,864,007 - 12,478,053 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	12,216,132 - 12,830,227 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	12,517,096 - 13,132,572 (-)	NCBI		UU_Cfam_GSD_1.0

Esrrg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	59,454,088 - 60,048,171 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936628	1,830,881 - 2,058,269 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936628	1,635,161 - 2,058,198 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ESRRG
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	6,712,860 - 6,941,501 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	6,710,615 - 7,371,419 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	8,646,197 - 8,720,519 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ESRRG
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	12,495,234 - 13,090,739 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	12,866,321 - 13,090,733 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	12,918,159 - 13,515,132 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Esrrg
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624835	812,742 - 1,015,767 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624835	815,230 - 1,326,376 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Esrrg
3092 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	236
Count of miRNA genes:	140
Interacting mature miRNAs:	188
Transcripts:	ENSRNOT00000003489
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	56056920	101056920	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	61825626	106807694	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	65103704	106807694	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	65103704	106807694	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	74862117	101339893	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	80753256	106807694	Rat

Markers in Region

D13Rat47

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	99,258,249 - 99,258,417 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	106,156,025 - 106,156,192	NCBI	Rnor6.0
Rnor_5.0	13	110,802,823 - 110,802,990	UniSTS	Rnor5.0
RGSC_v3.4	13	103,828,388 - 103,828,555	UniSTS	RGSC3.4
RGSC_v3.4	13	103,828,387 - 103,828,555	RGD	RGSC3.4
RGSC_v3.1	13	104,017,431 - 104,017,598	RGD
Celera	13	98,754,181 - 98,754,348	UniSTS
RH 3.4 Map	13	669.2	RGD
RH 3.4 Map	13	669.2	UniSTS
RH 2.0 Map	13	728.0	RGD
FHH x ACI Map	13	57.9	RGD
Cytogenetic Map	13	q26	UniSTS

D13Rat49

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	99,778,880 - 99,779,019 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	106,676,710 - 106,676,848	NCBI	Rnor6.0
Rnor_5.0	13	111,322,467 - 111,322,605	UniSTS	Rnor5.0
RGSC_v3.4	13	104,400,153 - 104,400,291	UniSTS	RGSC3.4
RGSC_v3.4	13	104,400,047 - 104,400,321	RGD	RGSC3.4
RGSC_v3.1	13	104,589,196 - 104,589,334	RGD
Celera	13	99,273,152 - 99,273,290	UniSTS
RH 3.4 Map	13	682.5	RGD
RH 3.4 Map	13	682.5	UniSTS
RH 2.0 Map	13	730.3	RGD
FHH x ACI Map	13	58.79	RGD
Cytogenetic Map	13	q26	UniSTS

D13Got95

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	99,438,205 - 99,438,312 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	106,338,935 - 106,339,041	NCBI	Rnor6.0
Rnor_5.0	13	110,985,046 - 110,985,152	UniSTS	Rnor5.0
RGSC_v3.4	13	104,009,971 - 104,010,078	RGD	RGSC3.4
RGSC_v3.4	13	104,009,972 - 104,010,078	UniSTS	RGSC3.4
RGSC_v3.1	13	104,199,015 - 104,199,121	RGD
Celera	13	98,933,677 - 98,933,783	UniSTS
RH 3.4 Map	13	682.6	UniSTS
RH 3.4 Map	13	682.6	RGD
RH 2.0 Map	13	728.8	RGD
Cytogenetic Map	13	q26	UniSTS

D13Got94

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	99,399,358 - 99,399,487 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	106,300,059 - 106,300,187	NCBI	Rnor6.0
Rnor_5.0	13	110,946,170 - 110,946,298	UniSTS	Rnor5.0
RGSC_v3.4	13	103,970,590 - 103,970,719	RGD	RGSC3.4
RGSC_v3.4	13	103,970,591 - 103,970,719	UniSTS	RGSC3.4
RGSC_v3.1	13	104,159,634 - 104,159,762	RGD
Celera	13	98,895,394 - 98,895,522	UniSTS
RH 3.4 Map	13	683.9	UniSTS
RH 3.4 Map	13	683.9	RGD
RH 2.0 Map	13	747.5	RGD
Cytogenetic Map	13	q26	UniSTS

AU048237

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	99,248,165 - 99,248,325 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	106,145,941 - 106,146,100	NCBI	Rnor6.0
Rnor_5.0	13	110,792,739 - 110,792,898	UniSTS	Rnor5.0
RGSC_v3.4	13	103,818,304 - 103,818,463	UniSTS	RGSC3.4
Celera	13	98,744,111 - 98,744,270	UniSTS
Cytogenetic Map	13	q26	UniSTS

BE108002

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	99,560,440 - 99,560,645 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	106,459,171 - 106,459,375	NCBI	Rnor6.0
Rnor_5.0	13	111,105,529 - 111,105,733	UniSTS	Rnor5.0
RGSC_v3.4	13	104,133,489 - 104,133,693	UniSTS	RGSC3.4
Celera	13	99,055,270 - 99,055,474	UniSTS
RH 3.4 Map	13	683.2	UniSTS
Cytogenetic Map	13	q26	UniSTS

UniSTS:495942

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	99,608,638 - 99,608,729 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	106,507,415 - 106,507,505	NCBI	Rnor6.0
Rnor_5.0	13	111,153,773 - 111,153,863	UniSTS	Rnor5.0
RGSC_v3.4	13	104,182,190 - 104,182,280	UniSTS	RGSC3.4
Celera	13	99,103,440 - 99,103,530	UniSTS
Cytogenetic Map	13	q26	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		33							50	29
Low	3	10	53	37	10	37	8	11	24	6	34	9	8
Below cutoff			4	4	9	4					7	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001401443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001415123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001415124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_203336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB126962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB126963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY341057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000003489 ⟹ ENSRNOP00000003489

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	99,564,669 - 99,783,397 (+)	Ensembl
Rnor_6.0 Ensembl	13	106,463,368 - 106,683,436 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000095864 ⟹ ENSRNOP00000087260

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	99,566,225 - 99,783,397 (+)	Ensembl

RefSeq Acc Id:

NM_001401443 ⟹ NP_001388372

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	99,564,669 - 99,785,539 (+)	NCBI

RefSeq Acc Id:

NM_001415123 ⟹ NP_001402052

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	99,213,696 - 99,785,539 (+)	NCBI

RefSeq Acc Id:

NM_001415124 ⟹ NP_001402053

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	99,213,344 - 99,785,539 (+)	NCBI

RefSeq Acc Id:

NM_203336 ⟹ NP_976081

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	99,224,371 - 99,785,539 (+)	NCBI
Rnor_6.0	13	106,121,602 - 106,681,211 (+)	NCBI
Rnor_5.0	13	110,713,353 - 111,328,942 (+)	NCBI
RGSC_v3.4	13	103,794,661 - 104,405,301 (+)	RGD
Celera	13	98,720,991 - 99,277,811 (+)	RGD

Sequence:

show sequence

AAACACAGCTCAGCTGCTGCCCTGTACACACAGCCCTGGGAGCAGACCAAGCAGCACCTTCCCA
GCAGCCTTTTGAACCCGAGACTCTCCCAGATCCTCTCTTCGCCCAGGAAGTTTCCTTCTCTGTT
GTCAGATTTAGCACCAGACTCCCCCGTCATCAGATCCGAGCAGGCTCCCTGCTGCACAGTACAG
AGGCTTGCTTAAGACATTTGTCCTTGAAACTGCACCAAACTCTTGGAAGAGCCCAGAACGTTAG
AGTAACGTGCTGGTTCGTCAATGAAGCAAGCTGAAGTGATGAAGATGTAAGGAAAGCATCCTAC
GCTAACACTGTCGCAGTCGGAAAGGCTTCTCTGCAGAATGTCAAACAAAGATCGACACATTGAT
TCCAGCTGTTCGTCCTTCATCAAGACGGAACCCTCCAGCCCAGCCTCCCTGACGGACAGCGTCA
ACCACCACAGCCCTGGTGGATCTTCCGACGCCAGTGGGAGTTACAGTTCAACCATGAATGGCCA
TCAGAACGGACTGGACTCGCCACCTCTCTACCCCTCTGCTCCTATCCTGGGAGGCAGCGGTCCT
GTCCGGAAACTGTATGATGACTGCTCCAGCACCATCGTAGAGGATCCCCAGACCAAGTGTGAAT
ATATGCTCAACTCCATGCCCAAGAGACTGTGCTTAGTGTGTGGCGACATCGCCTCTGGGTATCA
CTATGGGGTTGCCTCATGTGAAGCCTGCAAGGCTTTCTTCAAGAGGACAATTCAAGGTAACATA
GAGTACAGCTGCCCGGCCACGAATGAATGTGAGATCACCAAGCGCAGACGCAAATCCTGCCAGG
CCTGCCGCTTCATGAAATGTCTCAAAGTGGGCATGCTGAAAGAAGGGGTCCGTCTTGACAGAGT
GCGTGGAGGTCGGCAGAAGTACAAGCGTAGAATAGATGCTGAGAACAGCCCATACCTGAACCCT
CAGCTGGTGCAGCCAGCCAAAAAGCCATATAACAAGATTGTCTCGCATTTGCTGGTGGCTGAAC
CAGAGAAGATCTATGCCATGCCTGACCCTACTGTCCCCGACAGTGACATCAAAGCCCTCACGAC
GCTCTGTGACTTGGCTGATCGAGAGTTGGTGGTTATCATTGGATGGGCAAAACATATCCCAGGC
TTCTCCACACTGTCCCTGGCGGATCAGATGAGCCTTCTCCAGAGCGCGTGGATGGAAATCTTGA
TCCTGGGTGTTGTGTACCGATCACTTTCGTTTGAGGATGAACTTGTCTATGCAGACGATTACAT
AATGGATGAAGACCAGTCCAAATTAGCAGGCCTTCTTGACCTAAATAACGCCATCCTGCAGCTG
GTGAAGAAATATAAAAGCATGAAGCTAGAGAAGGAAGAATTTGTCACCCTCAAAGCAATAGCTC
TTGCTAATTCAGATTCCATGCACATAGAAGACGTGGAGGCTGTCCAGAAACTTCAGGATGTGTT
GCACGAGGCCCTGCAGGATTACGAGGCTGGCCAGCACATGGAAGACCCACGCCGTGCAGGCAAG
ATGCTGATGACGCTGCCGCTCCTGAGGCAGACCTCCACCAAGGCGGTCCAACACTTCTACAACA
TCAAACTTGAAGGCAAAGTGCCCATGCACAAACTGTTTCTGGAAATGCTGGAAGCCAAGGTCTG
ACTAACAGCCCCCTGAGCCCTCCCGTCCTGCACGTTCAAAAGGGAAGATAAAACCCAAGAATGA
TGTCGAAGAATCTTAGAGTTTAGCGAACAACATTAAAATTCAACAGACTGCACTGATACCTTAG
CAGCCACAGTACGATGCAGCCTGATGCAGCCTGCGGATTCCGCCAATCTTCCTGTTAGGTTTCC
TCTACTTTATCCCATGATCCTCTGGCCACCTCCCTGCGTTCCCCACTCTTCCTTGTTCCGTTAT
TAAGTTTTGCTTCTTTCACTCAAGGTTCCTTCTCCCTCTCCCGCTTCCTTTCTTCTGCCCTCTT
CCTTTCTCTTCCTTTCCCCAATCTTCTTCTCTTGCCTTGTTCTTGTCCCTCCTCCCTTCCTCAC
AGCCCCTCCCACCCTACATATCCAACACCTCTAAGTGTACGGGACATTTCTTCCACCTCTTACG
TCTCTTCCCCACCTCTTCCTCCCCCATTTTTTCCTTTCCTTCCTTCTGCTGCTGAACTCTTAAA
AGCGGTCTCTAACTGGAGAGAGATGGAAACCAACCCTGCCAAAGGACAGAGATCCATACTATGG
ATGCCAGTGAACTTGTAGTGAACCATGACAGCCCCAGTGAGTAAGGAATCAAAGAGAGAACCGT
ACCTGAAGAACAGTGCAATGCAAACGAATCGACTTAGTGCAGTATTAGAGTCTACGGGGCAGCC
TCCGACCAGACAACCTAAGTGGCGGCGGCATCGGCTGCTTCTCCTTGCTTTCTCATCTAGATCA
GTTACAGCCATTTGATTCCTTAATTCTTTTGTCAAGTCTTCCAGGTGTTGGTTAGTTTAGCTAC
TATGTAACTTTTTCAGGGAATCGTTTAAGCTTTATTCATTCATGCAATACTAGAGAGGGGTAAG
GATACCGCAACCTCGTGCTGGCTTTGAACAATTGAACACTAATGAAGGACAAATGAACCCTGAA
GGAAGATTTTTAAAAATGTTTTGTTTCTTCTTACAAATGGAGATTTTTTTGTACCAGCTTTACC
ACTTTTCAGCCATTTATTAATATGGGGATTTAACTTACTCAAGCAATAGTTGAAGGGAAGGTGC
ATATTACCACGGATGCAATTTATGTCGTGTGCCAGTCTGGTCCCAAACATCTCTTTCTTACATG
AGCTCCAGTTTGCCTAAATGTTCACTGACACCAAGGATTAGATTATACCTACCGTGACACCGAG
TGGTCCCGTCCACGAGCACTGCACATGGGATCCCTATCTGTAGAATTAGCACCAGTACACCTCC
CTGCTGGGAGGGACAGTCGCCATACGATTTCTAGCTGCACTCGTGGTTAGGAACAAGATGCTGC
CTGTATGCAGTTGCAAACTCTGTCTCAGAAGGAGCTGTGAGCCAATATTTCAGAGGCAATAAGG
CTAATGCCAGAATTCAAACAAACCAACCGTCAAAGACAGCAGACACCTGACCAAATTCTAAAGT
CCTAATCCGTAGGAGTTGATCCACTTTAGGAATGGTTGTTTCAATTAACCTGCAG

hide sequence

RefSeq Acc Id:

XM_017598866 ⟹ XP_017454355

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	99,167,656 - 99,788,016 (+)	NCBI
Rnor_6.0	13	106,063,799 - 106,683,353 (+)	NCBI

Sequence:

show sequence

AGGCCCAGCTCCCAACCGGTTCAGCGTCCGCAGCGGGAAGGCCAGGACGGCCGGTGACCAGGCG
GACATCCTCGGGGACCCCCAAAGCCACCCACCCCGAGAGCTCGGAGAGCGGCTCTGCACGCGGG
ACCTTTAGAGTAACGTGCTGGTTCGTCAATGAAGCAAGCTGAAGTGATGAAGATGTAAGGAAAG
CATCCTACGCTAACACTGTCGCAGTCGGAAAGGCTTCTCTGCAGAATGTCAAACAAAGATCGAC
ACATTGATTCCAGCTGTTCGTCCTTCATCAAGACGGAACCCTCCAGCCCAGCCTCCCTGACGGA
CAGCGTCAACCACCACAGCCCTGGTGGATCTTCCGACGCCAGTGGGAGTTACAGTTCAACCATG
AATGGCCATCAGAACGGACTGGACTCGCCACCTCTCTACCCCTCTGCTCCTATCCTGGGAGGCA
GCGGTCCTGTCCGGAAACTGTATGATGACTGCTCCAGCACCATCGTAGAGGATCCCCAGACCAA
GTGTGAATATATGCTCAACTCCATGCCCAAGAGACTGTGCTTAGTGTGTGGCGACATCGCCTCT
GGGTATCACTATGGGGTTGCCTCATGTGAAGCCTGCAAGGCTTTCTTCAAGAGGACAATTCAAG
GTAACATAGAGTACAGCTGCCCGGCCACGAATGAATGTGAGATCACCAAGCGCAGACGCAAATC
CTGCCAGGCCTGCCGCTTCATGAAATGTCTCAAAGTGGGCATGCTGAAAGAAGGGGTCCGTCTT
GACAGAGTGCGTGGAGGTCGGCAGAAGTACAAGCGTAGAATAGATGCTGAGAACAGCCCATACC
TGAACCCTCAGCTGGTGCAGCCAGCCAAAAAGCCATATAACAAGATTGTCTCGCATTTGCTGGT
GGCTGAACCAGAGAAGATCTATGCCATGCCTGACCCTACTGTCCCCGACAGTGACATCAAAGCC
CTCACGACGCTCTGTGACTTGGCTGATCGAGAGTTGGTGGTTATCATTGGATGGGCAAAACATA
TCCCAGGCTTCTCCACACTGTCCCTGGCGGATCAGATGAGCCTTCTCCAGAGCGCGTGGATGGA
AATCTTGATCCTGGGTGTTGTGTACCGATCACTTTCGTTTGAGGATGAACTTGTCTATGCAGAC
GATTACATAATGGATGAAGACCAGTCCAAATTAGCAGGCCTTCTTGACCTAAATAACGCCATCC
TGCAGCTGGTGAAGAAATATAAAAGCATGAAGCTAGAGAAGGAAGAATTTGTCACCCTCAAAGC
AATAGCTCTTGCTAATTCAGATTCCATGCACATAGAAGACGTGGAGGCTGTCCAGAAACTTCAG
GATGTGTTGCACGAGGCCCTGCAGGATTACGAGGCTGGCCAGCACATGGAAGACCCACGCCGTG
CAGGCAAGATGCTGATGACGCTGCCGCTCCTGAGGCAGACCTCCACCAAGGCGGTCCAACACTT
CTACAACATCAAACTTGAAGGCAAAGTGCCCATGCACAAACTGTTTCTGGAAATGCTGGAAGCC
AAGGTCTGACTAACAGCCCCCTGAGCCCTCCCGTCCTGCACGTTCAAAAGGGAAGATAAAACCC
AAGAATGATGTCGAAGAATCTTAGAGTTTAGCGAACAACATTAAAATTCAACAGACTGCACTGA
TACCTTAGCAGCCACAGTACGATGCAGCCTGATGCAGCCTGCGGATTCCGCCAATCTTCCTGTT
AGGTTTCCTCTACTTTATCCCATGATCCTCTGGCCACCTCCCTGCGTTCCCCACTCTTCCTTGT
TCCGTTATTAAGTTTTGCTTCTTTCACTCAAGGTTCCTTCTCCCTCTCCCGCTTCCTTTCTTCT
GCCCTCTTCCTTTCTCTTCCTTTCCCCAATCTTCTTCTCTTGCCTTGTTCTTGTCCCTCCTCCC
TTCCTCACAGCCCCTCCCACCCTACATATCCAACACCTCTAAGTGTACGGGACATTTCTTCCAC
CTCTTACGTCTCTTCCCCACCTCTTCCTCCCCCATTTTTTCCTTTCCTTCCTTCTGCTGCTGAA
CTCTTAAAAGCGGTCTCTAACTGGAGAGAGATGGAAACCAACCCTGCCAAAGGACAGAGATCCA
TACTATGGATGCCAGTGAACTTGTAGTGAACCATGACAGCCCCAGTGAGTAAGGAATCAAAGAG
AGAACCGTACCTGAAGAACAGTGCAATGCAAACGAATCGACTTAGTGCAGTATTAGAGTCTACG
GGGCAGCCTCCGACCAGACAACCTAAGTGGCGGCGGCATCGGCTGCTTCTCCTTGCTTTCTCAT
CTAGATCAGTTACAGCCATTTGATTCCTTAATTCTTTTGTCAAGTCTTCCAGGTGTTGGTTAGT
TTAGCTACTATGTAACTTTTTCAGGGAATCGTTTAAGCTTTATTCATTCATGCAATACTAGAGA
GGGGTAAGGATACCGCAACCTCGTGCTGGCTTTGAACAATTGAACACTAATGAAGGACAAATGA
ACCCTGAAGGAAGATTTTTAAAAATGTTTTGTTTCTTCTTACAAATGGAGATTTTTTTGTACCA
GCTTTACCACTTTTCAGCCATTTATTAATATGGGGATTTAACTTACTCAAGCAATAGTTGAAGG
GAAGGTGCATATTACCACGGATGCAATTTATGTCGTGTGCCAGTCTGGTCCCAAACATCTCTTT
CTTACATGAGCTCCAGTTTGCCTAAATGTTCACTGACACCAAGGATTAGATTATACCTACCGTG
ACACCGAGTGGTCCCGTCCACGAGCACTGCACATGGGATCCCTATCTGTAGAATTAGCACCAGT
ACACCTCCCTGCTGGGAGGGACAGTCGCCATACGATTTCTAGCTGCACTCGTGGTTAGGAACAA
GATGCTGCCTGTATGCAGTTGCAAACTCTGTCTCAGAAGGAGCTGTGAGCCAATATTTCAGAGG
CAATAAGGCTAATGCCAGAATTCAAACAAACCAACCGTCAAAGACAGCAGACACCTGACCAAAT
TCTAAAGTCCTAATCCGTAGGAGTTGATCCACTTTAGGAATGGTTGTTTCAATTAACCTGCAGG
TTTGTTTTGTTTCGTTGTTTGTTTTTTAACCAAAAGCTAAGCCAATAGATGTGCTTTTCAACAA
GCGTGGTCACAGCACGAAGGTCAGTCAGGTTTCAGACTGTAACCAGGTGTAATCTAATGAAGAA
ATCAGATGCCCCCTCCCGAAACCTACAGTCGCCCGCCGAATAACCAGAAAACAGTAACCTCCAT
AGAATGCTTTACCAATGGACCAGTGTTAGTAGCTGCTCTCTGTATTCTGTGGATAGTCTTACTC
TATGTACACAGATGTAATTAAAGTTGTACCCCTAACAAACAAAAGAATAGTTCAGCTTCAATGT
TCCATGTTCGCTGCGCTTTTCTGAACTTTACGTTGCATTCAGAAACTGTCGTCTTGTTCTCGTG
GTGTTTGGATTCTTGTGGTGTGTGCTTTTAGACACAGGGTAGAATTAGAGACAGTATTGGATGT
ATACTTCCTCAGGAGACCACAGTAGTATCTTCTACTCCTTACCAGTAATAACTAAGAGATTGAA
ACTCCAAAACAGTATTCATTATGATCAGACACACATCAAAATCATAATATTTTCAAAAAAGGGA
TAATTTCTCTAATGGTTTATTATAGAATACCAATGTATAGCTTAGACATAAAACTTTGAATATT
CAAGAATATAGATAAGTCTAATTTTTAAATGCTGTATATATGGCTTTCCCCTGATCATCTCTCA
GATGTTGTTATTAACTCGCTCTGTGTTGTTGCAAACCCTTTTGGTGCGGACTTGCTTCCAAAAC
TATTGCTACTTTGTGTGCGTTAAGCAAAATACCTTGGACTGAGGACGTCTCAGCCCTGTGCTAG
GAATACTGTGTATCTATCATTAGCTATGTGGGAATATATCGTAGATTGTGGTTCTCAGTAGAGA
AAGTGACTGTAGTGTGAATCTAGGTAAATCATCGTTAGCAATTCATTCGGATGGTCGATAACTT
GAAATTGATAGCTGTGATAAGTTAAAAAAAAATTGGCAAATCCCTGACTAAACATCAACAGAAA
ATACAACTCCTGGGGGGTGGGGGAAGGTGCTCATCCTGTAAGATTCTTCATCATGTATGTGTTC
AAAACATTATTTTGCAGAAGGTTTATGCAGGGTTTAAGTTACTATTGCGCAATTACGCTATGTG
TACAAAAGGAATATAAAGTGTATCGACCACCTCACTGAGTCACACCCGAGGGTCTGAGCTTCAG
AAGCCAGAGCCCGCAAGTGATCGTGAGACAGAAACACATTTAAAGAATGAGGTACAATGTGTCG
TCCTCTGTTTAAAAGACTTGGCCTTTGAAAACAACAAGTATCTCACAACTGAAGTGAAAAAAAA
AAAAAACAGCTTGAAATGTAGATCTAAAAGGAACGCACGGGCTTCTGGGTAGATGCCATTTGTA
CCTTGCTCGAGCAAAGTTGATCGTTTTTTCAAGTTTCTAGCAAGACCATTTAGTTAATGCCAGC
TGTCGGGAAGATACCAAGGTGTATGTTTTAGCCATGCAATTTACAGTTTTATTTTCCTTTTAGG
TTTGTTCTTATTTAAGGCGATATGATTGTTTTGGCTCCTTGTAGTGACTCTTCGTGTTTTAATC
AAGTCAGATTGTTGTATTTATTCCACTATTTTGCATTTAAATGATGACATAAAAGATATAAAAA
ATTTAAAACTGCTATTTTTCTTATAGAAGAGAAAATGGATGTTGGTGATTGTATTTTAATTATT
TAAGCATCTCTGTTTACCTGCCTGGGACAACATTTTATGGCAGTCTTATGTGCAAAGATCCTAA
ATGGACAAAACAAAATTTAAACTGCTTACAATGATCCAGGAGTTGCATTATAGCCAATAGTAAA
AATAATAATGATAATAATAATTAATAATAATAATGAAACCATGTCTATAGCTGTAGATGGGCAT
CACATCTGTAAAGCAATCAATTGTATATTTTTGTGATGTGTACCATACTGTGTGCTCCAGCAAA
TGTCCATTTGTGTAAATGTATTTATTTTATATTGTATATATTGTTAAATGCAAAAAGGAGCTAT
GATTCTGTGACTCCAATCAGTTCAGATATGTAACTCAAATTATTATGCCTTTCAGGAGGATGGT
AGAACAATATTAAACAAGCTTCCACTTTT

hide sequence

RefSeq Acc Id:

XM_039090940 ⟹ XP_038946868

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	99,167,656 - 99,788,016 (+)	NCBI

RefSeq Acc Id:

XM_039090941 ⟹ XP_038946869

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	99,485,359 - 99,788,016 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001388372	(Get FASTA)	NCBI Sequence Viewer
	NP_001402052	(Get FASTA)	NCBI Sequence Viewer
	NP_001402053	(Get FASTA)	NCBI Sequence Viewer
	NP_976081	(Get FASTA)	NCBI Sequence Viewer
	XP_017454355	(Get FASTA)	NCBI Sequence Viewer
	XP_038946868	(Get FASTA)	NCBI Sequence Viewer
	XP_038946869	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAQ90023	(Get FASTA)	NCBI Sequence Viewer
	BAD08616	(Get FASTA)	NCBI Sequence Viewer
	BAD08617	(Get FASTA)	NCBI Sequence Viewer
	EDL94943	(Get FASTA)	NCBI Sequence Viewer
	EDL94944	(Get FASTA)	NCBI Sequence Viewer
	P62510	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_976081 ⟸ NM_203336
- Peptide Label:	isoform 2
- UniProtKB:	P62510 (UniProtKB/Swiss-Prot), A6JGU0 (UniProtKB/TrEMBL), A0A8I6A6X6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPS APILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAF FKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRID AENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVI IGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLL DLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQH MEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV hide sequence

RefSeq Acc Id:	XP_017454355 ⟸ XM_017598866
- Peptide Label:	isoform X2
- UniProtKB:	P62510 (UniProtKB/Swiss-Prot), A6JGU0 (UniProtKB/TrEMBL), A0A8I6A6X6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPS APILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAF FKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRID AENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVI IGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLL DLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQH MEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV hide sequence

RefSeq Acc Id:

ENSRNOP00000003489 ⟸ ENSRNOT00000003489

RefSeq Acc Id:	XP_038946868 ⟸ XM_039090940
- Peptide Label:	isoform X2
- UniProtKB:	A6JGU0 (UniProtKB/TrEMBL), A0A8I6A6X6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946869 ⟸ XM_039090941
- Peptide Label:	isoform X2
- UniProtKB:	A6JGU0 (UniProtKB/TrEMBL), A0A8I6A6X6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000087260 ⟸ ENSRNOT00000095864

RefSeq Acc Id:	NP_001402053 ⟸ NM_001415124
- Peptide Label:	isoform 2
- UniProtKB:	A6JGU0 (UniProtKB/TrEMBL), A0A8I6A6X6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001402052 ⟸ NM_001415123
- Peptide Label:	isoform 2
- UniProtKB:	A6JGU0 (UniProtKB/TrEMBL), A0A8I6A6X6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001388372 ⟸ NM_001401443
- Peptide Label:	isoform 1
- UniProtKB:	Q75T51 (UniProtKB/Swiss-Prot), Q5QJE4 (UniProtKB/Swiss-Prot), P62510 (UniProtKB/Swiss-Prot), Q75T52 (UniProtKB/Swiss-Prot), A6JGT8 (UniProtKB/TrEMBL), A0A8I6A6X6 (UniProtKB/TrEMBL)

Protein Domains

NR LBD Nuclear receptor

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P62510-F1-model_v2	AlphaFold	P62510	1-458	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303236	AgrOrtholog
BioCyc Gene	G2FUF-16932	BioCyc
Ensembl Genes	ENSRNOG00000002593	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000003489	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000087260.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000003489	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000095864.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.565.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.50.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Est_rcpt/est-rel_rcp	UniProtKB/TrEMBL
	NHR-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Nucl_hrmn_rcpt_lig-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Nuclear_hrmn_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Oest-rel_rcp	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Oest_rcpt/oest-rel_rcp	UniProtKB/Swiss-Prot
	Retinoic_acid_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_hrmn_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_NHR/GATA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:360896	UniProtKB/Swiss-Prot
NCBI Gene	360896	ENTREZGENE
PANTHER	ESTROGEN-RELATED RECEPTOR GAMMA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	KNIRPS-RELATED PROTEIN-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Hormone_recep	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-C4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Esrrg	PhenoGen
PIRSF	ER-like_NR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ERR1-2-3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	RETNOICACIDR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	STRDHORMONER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	STROIDFINGER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	NR_LBD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NUCLEAR_REC_DBD_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NUCLEAR_REC_DBD_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	HOLI	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZnF_C4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF48508	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6A6X6	ENTREZGENE, UniProtKB/TrEMBL
	A6JGT8	ENTREZGENE, UniProtKB/TrEMBL
	A6JGU0	ENTREZGENE, UniProtKB/TrEMBL
	ERR3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q5QJE4	ENTREZGENE
	Q75T51	ENTREZGENE
	Q75T52	ENTREZGENE
UniProt Secondary	Q5QJE4	UniProtKB/Swiss-Prot
	Q75T51	UniProtKB/Swiss-Prot
	Q75T52	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-11-17	Esrrg	estrogen-related receptor gamma			Symbol updated	1299863	APPROVED
2005-07-14	errg	estrogen-related receptor gamma			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_physical_interaction	recognizes inverted and direct DNA repeats with AGGTCA halfsites	1334481

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD