Esrrg (estrogen-related receptor gamma) - Rat Genome Database

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Gene: Esrrg (estrogen-related receptor gamma) Rattus norvegicus
Analyze
Symbol: Esrrg
Name: estrogen-related receptor gamma
RGD ID: 1303236
Description: Predicted to have several functions, including AF-2 domain binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and identical protein binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Orthologous to human ESRRG (estrogen related receptor gamma); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: errg; estrogen receptor-related protein 3; nuclear receptor subfamily 3 group B member 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21399,167,656 - 99,788,016 (+)NCBI
Rnor_6.0 Ensembl13106,463,368 - 106,683,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.013106,063,799 - 106,683,353 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013110,713,353 - 111,328,942 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413103,794,661 - 104,405,301 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113103,983,703 - 104,594,344 (+)NCBI
Celera1398,720,991 - 99,277,811 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-di-tert-butylphenol  (ISO)
2-arachidonoylglycerol  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-chloro-m-cresol  (ISO)
4-ethylphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-isopropylphenol  (ISO)
4-tert-butylphenol  (ISO)
4-tert-Octylphenol  (ISO)
5,6,7,8-tetrahydro-2-naphthol  (ISO)
8-Br-cAMP  (ISO)
afimoxifene  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
Benzyl parahydroxybenzoate  (ISO)
biochanin A  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylparaben  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
daidzein  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
Ethyl salicylate  (ISO)
ethylparaben  (ISO)
fenthion  (ISO)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
glyphosate  (EXP)
GSK 4716  (ISO)
lithium chloride  (ISO)
LY294002  (ISO)
methapyrilene  (ISO)
methyl salicylate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
nickel atom  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
p-tert-Amylphenol  (ISO)
paracetamol  (EXP,ISO)
phenol red  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propylparaben  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zalcitabine  (EXP)
zoledronic acid  (ISO)

References

Additional References at PubMed
PMID:10428842   PMID:12715898   PMID:15149736   PMID:17079227   PMID:21911493   PMID:23404793   PMID:23836911   PMID:26404484  


Genomics

Comparative Map Data
Esrrg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21399,167,656 - 99,788,016 (+)NCBI
Rnor_6.0 Ensembl13106,463,368 - 106,683,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.013106,063,799 - 106,683,353 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013110,713,353 - 111,328,942 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413103,794,661 - 104,405,301 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113103,983,703 - 104,594,344 (+)NCBI
Celera1398,720,991 - 99,277,811 (+)NCBICelera
Cytogenetic Map13q26NCBI
ESRRG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1216,503,246 - 217,137,755 (-)EnsemblGRCh38hg38GRCh38
GRCh381216,503,246 - 217,137,702 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371216,676,588 - 217,311,044 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361214,743,211 - 215,329,599 (-)NCBINCBI36hg18NCBI36
Build 341213,064,982 - 213,651,371NCBI
Celera1189,900,435 - 190,535,016 (-)NCBI
Cytogenetic Map1q41NCBI
HuRef1187,351,966 - 187,986,618 (-)NCBIHuRef
CHM1_11217,949,719 - 218,583,931 (-)NCBICHM1_1
Esrrg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,340,707 - 187,947,082 (+)NCBIGRCm39mm39
GRCm39 Ensembl1187,340,988 - 187,947,082 (+)Ensembl
GRCm381187,608,510 - 188,214,885 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,608,791 - 188,214,885 (+)EnsemblGRCm38mm10GRCm38
MGSCv371189,821,738 - 190,038,763 (+)NCBIGRCm37mm9NCBIm37
MGSCv361189,698,647 - 189,915,672 (+)NCBImm8
Celera1194,923,141 - 195,141,266 (+)NCBICelera
Cytogenetic Map1H5- H6NCBI
Esrrg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554061,560,485 - 1,788,250 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554061,260,240 - 1,784,652 (+)NCBIChiLan1.0ChiLan1.0
ESRRG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11196,929,197 - 197,508,064 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1196,929,197 - 197,153,195 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01192,074,260 - 192,667,610 (-)NCBIMhudiblu_PPA_v0panPan3
ESRRG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13811,825,055 - 12,439,143 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3811,823,520 - 12,256,028 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3811,862,256 - 12,476,998 (-)NCBI
ROS_Cfam_1.03811,851,190 - 12,466,509 (-)NCBI
UMICH_Zoey_3.13811,864,007 - 12,478,053 (-)NCBI
UNSW_CanFamBas_1.03812,216,132 - 12,830,227 (-)NCBI
UU_Cfam_GSD_1.03812,517,096 - 13,132,572 (-)NCBI
Esrrg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934459,454,088 - 60,048,171 (+)NCBI
SpeTri2.0NW_0049366281,635,161 - 2,058,198 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESRRG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl106,712,841 - 7,030,063 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1106,710,615 - 7,371,419 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2108,646,197 - 8,720,519 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ESRRG
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12512,495,234 - 13,090,739 (+)NCBI
ChlSab1.1 Ensembl2512,866,321 - 13,090,733 (+)Ensembl
Esrrg
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624835815,230 - 1,326,376 (-)NCBI

Position Markers
D13Rat47  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.013106,156,025 - 106,156,192NCBIRnor6.0
Rnor_5.013110,802,823 - 110,802,990UniSTSRnor5.0
RGSC_v3.413103,828,388 - 103,828,555UniSTSRGSC3.4
RGSC_v3.413103,828,387 - 103,828,555RGDRGSC3.4
RGSC_v3.113104,017,431 - 104,017,598RGD
Celera1398,754,181 - 98,754,348UniSTS
RH 3.4 Map13669.2RGD
RH 3.4 Map13669.2UniSTS
RH 2.0 Map13728.0RGD
FHH x ACI Map1357.9RGD
Cytogenetic Map13q26UniSTS
D13Rat49  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.013106,676,710 - 106,676,848NCBIRnor6.0
Rnor_5.013111,322,467 - 111,322,605UniSTSRnor5.0
RGSC_v3.413104,400,153 - 104,400,291UniSTSRGSC3.4
RGSC_v3.413104,400,047 - 104,400,321RGDRGSC3.4
RGSC_v3.113104,589,196 - 104,589,334RGD
Celera1399,273,152 - 99,273,290UniSTS
RH 3.4 Map13682.5RGD
RH 3.4 Map13682.5UniSTS
RH 2.0 Map13730.3RGD
FHH x ACI Map1358.79RGD
Cytogenetic Map13q26UniSTS
D13Got95  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.013106,338,935 - 106,339,041NCBIRnor6.0
Rnor_5.013110,985,046 - 110,985,152UniSTSRnor5.0
RGSC_v3.413104,009,972 - 104,010,078UniSTSRGSC3.4
RGSC_v3.413104,009,971 - 104,010,078RGDRGSC3.4
RGSC_v3.113104,199,015 - 104,199,121RGD
Celera1398,933,677 - 98,933,783UniSTS
RH 3.4 Map13682.6RGD
RH 3.4 Map13682.6UniSTS
RH 2.0 Map13728.8RGD
Cytogenetic Map13q26UniSTS
D13Got94  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.013106,300,059 - 106,300,187NCBIRnor6.0
Rnor_5.013110,946,170 - 110,946,298UniSTSRnor5.0
RGSC_v3.413103,970,591 - 103,970,719UniSTSRGSC3.4
RGSC_v3.413103,970,590 - 103,970,719RGDRGSC3.4
RGSC_v3.113104,159,634 - 104,159,762RGD
Celera1398,895,394 - 98,895,522UniSTS
RH 3.4 Map13683.9RGD
RH 3.4 Map13683.9UniSTS
RH 2.0 Map13747.5RGD
Cytogenetic Map13q26UniSTS
AU048237  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.013106,145,941 - 106,146,100NCBIRnor6.0
Rnor_5.013110,792,739 - 110,792,898UniSTSRnor5.0
RGSC_v3.413103,818,304 - 103,818,463UniSTSRGSC3.4
Celera1398,744,111 - 98,744,270UniSTS
Cytogenetic Map13q26UniSTS
BE108002  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.013106,459,171 - 106,459,375NCBIRnor6.0
Rnor_5.013111,105,529 - 111,105,733UniSTSRnor5.0
RGSC_v3.413104,133,489 - 104,133,693UniSTSRGSC3.4
Celera1399,055,270 - 99,055,474UniSTS
RH 3.4 Map13683.2UniSTS
Cytogenetic Map13q26UniSTS
UniSTS:495942  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.013106,507,415 - 106,507,505NCBIRnor6.0
Rnor_5.013111,153,773 - 111,153,863UniSTSRnor5.0
RGSC_v3.413104,182,190 - 104,182,280UniSTSRGSC3.4
Celera1399,103,440 - 99,103,530UniSTS
Cytogenetic Map13q26UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131107975663Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1312193394108478121Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1324502279108770533Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1335301263107975663Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1362975663107975663Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1366971778111971778Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1371230858114033958Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1371230858114033958Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1372583716114033958Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)777694986114033958Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1380403559108770687Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1386833393114033958Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:140
Interacting mature miRNAs:188
Transcripts:ENSRNOT00000003489
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 33 50 29
Low 3 10 53 37 10 37 8 11 24 6 34 9 8
Below cutoff 4 4 9 4 7 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_203336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB126962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB126963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY341057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000003489   ⟹   ENSRNOP00000003489
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl13106,463,368 - 106,683,436 (+)Ensembl
RefSeq Acc Id: NM_203336   ⟹   NP_976081
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21399,224,371 - 99,783,397 (+)NCBI
Rnor_6.013106,121,602 - 106,681,211 (+)NCBI
Rnor_5.013110,713,353 - 111,328,942 (+)NCBI
RGSC_v3.413103,794,661 - 104,405,301 (+)RGD
Celera1398,720,991 - 99,277,811 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250443   ⟹   XP_006250505
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21399,562,470 - 99,788,016 (+)NCBI
Rnor_6.013106,458,985 - 106,683,353 (+)NCBI
Rnor_5.013110,713,353 - 111,328,942 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598864   ⟹   XP_017454353
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013106,065,331 - 106,683,353 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598865   ⟹   XP_017454354
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013106,257,837 - 106,683,353 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598866   ⟹   XP_017454355
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21399,167,656 - 99,788,016 (+)NCBI
Rnor_6.013106,063,799 - 106,683,353 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598867   ⟹   XP_017454356
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21399,212,734 - 99,788,016 (+)NCBI
Rnor_6.013106,109,770 - 106,683,353 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598868   ⟹   XP_017454357
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21399,213,554 - 99,788,016 (+)NCBI
Rnor_6.013106,110,781 - 106,683,353 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598869   ⟹   XP_017454358
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013106,201,012 - 106,683,353 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598870   ⟹   XP_017454359
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013106,458,985 - 106,683,353 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090940   ⟹   XP_038946868
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21399,167,656 - 99,788,016 (+)NCBI
RefSeq Acc Id: XM_039090941   ⟹   XP_038946869
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21399,485,359 - 99,788,016 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_976081   ⟸   NM_203336
- UniProtKB: P62510 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250505   ⟸   XM_006250443
- Peptide Label: isoform X1
- UniProtKB: P62510 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017454355   ⟸   XM_017598866
- Peptide Label: isoform X2
- UniProtKB: P62510 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017454353   ⟸   XM_017598864
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017454356   ⟸   XM_017598867
- Peptide Label: isoform X2
- UniProtKB: P62510 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017454357   ⟸   XM_017598868
- Peptide Label: isoform X2
- UniProtKB: P62510 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017454358   ⟸   XM_017598869
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017454354   ⟸   XM_017598865
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017454359   ⟸   XM_017598870
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000003489   ⟸   ENSRNOT00000003489
RefSeq Acc Id: XP_038946868   ⟸   XM_039090940
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946869   ⟸   XM_039090941
- Peptide Label: isoform X2
Protein Domains
NR LBD

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699102
Promoter ID:EPDNEW_R9626
Type:single initiation site
Name:Esrrg_1
Description:estrogen-related receptor gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013106,463,422 - 106,463,482EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303236 AgrOrtholog
Ensembl Genes ENSRNOG00000002593 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000003489 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003489 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot
  3.30.50.10 UniProtKB/Swiss-Prot
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot
  Oest-rel_rcp UniProtKB/Swiss-Prot
  Oest_rcpt/oest-rel_rcp UniProtKB/Swiss-Prot
  Retinoic_acid_rcpt UniProtKB/Swiss-Prot
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot
  Znf_NHR/GATA UniProtKB/Swiss-Prot
KEGG Report rno:360896 UniProtKB/Swiss-Prot
NCBI Gene 360896 ENTREZGENE
Pfam Hormone_recep UniProtKB/Swiss-Prot
  zf-C4 UniProtKB/Swiss-Prot
PhenoGen Esrrg PhenoGen
PIRSF ER-like_NR UniProtKB/Swiss-Prot
  ERR1-2-3 UniProtKB/Swiss-Prot
PRINTS RETNOICACIDR UniProtKB/Swiss-Prot
  STRDHORMONER UniProtKB/Swiss-Prot
  STROIDFINGER UniProtKB/Swiss-Prot
PROSITE NR_LBD UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot
SMART HOLI UniProtKB/Swiss-Prot
  ZnF_C4 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48508 UniProtKB/Swiss-Prot
UniProt ERR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q5QJE4 UniProtKB/Swiss-Prot
  Q75T51 UniProtKB/Swiss-Prot
  Q75T52 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Esrrg  estrogen-related receptor gamma      Symbol updated 1299863 APPROVED
2005-07-14 errg  estrogen-related receptor gamma      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction recognizes inverted and direct DNA repeats with AGGTCA halfsites 1334481