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Gene: Rhoa (ras homolog family member A) Rattus norvegicus
Symbol: Rhoa
Name: ras homolog family member A
RGD ID: 619921
Description: Exhibits several functions, including GTPase activity; Rho GDP-dissociation inhibitor binding activity; and purine ribonucleoside binding activity. Involved in several processes, including generation of neurons; intracellular signal transduction; and positive regulation of apoptotic process. Localizes to axon; cytosol; and membrane. Used to study membranous glomerulonephritis. Biomarker of asthma; fetal alcohol syndrome; hypertension; obesity; and pulmonary hypertension. Human ortholog(s) of this gene implicated in breast carcinoma. Orthologous to human RHOA (ras homolog family member A); PARTICIPATES IN calcium signaling pathway via the calcium-sensing receptor; E-cadherin signaling pathway; eicosanoid signaling pathway; INTERACTS WITH (R)-mevalonic acid; (S)-(-)-perillyl alcohol; 1-octadec-9-enoylglycero-3-phosphate.
Type: protein-coding
Also known as: Arha; Arha2; MGC72339; plysia ras-related homolog A2; ras homolog gene family, member A; transforming protein RhoA
Homo sapiens (human) : RHOA (ras homolog family member A)  HGNC  Alliance
Mus musculus (house mouse) : Rhoa (ras homolog family member A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rhoa (ras homolog family member A)
Pan paniscus (bonobo/pygmy chimpanzee) : RHOA (ras homolog family member A)
Canis lupus familiaris (dog) : RHOA (ras homolog family member A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rhoa (ras homolog family member A)
Sus scrofa (pig) : RHOA (ras homolog family member A)
Chlorocebus sabaeus (African green monkey) : RHOA (ras homolog family member A)
Heterocephalus glaber (naked mole-rat) : Rhoa (ras homolog family member A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08117,082,440 - 117,116,244 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,106,576 - 117,116,167 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,431,244 - 116,464,932 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,319,010 - 108,327,586 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Rhoa
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619921
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.