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Gene: Trim8 (tripartite motif-containing 8) Rattus norvegicus
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Symbol: Trim8
Name: tripartite motif-containing 8
Description: Predicted to have protein homodimerization activity. Predicted to be involved in several processes, including negative regulation of viral process; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of NF-kappaB transcription factor activity. Predicted to localize to the PML body and cytosol. Orthologous to human TRIM8 (tripartite motif containing 8); INTERACTS WITH (+)-schisandrin B; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC308181; LOC688785; probable E3 ubiquitin-protein ligase TRIM8; similar to Tripartite motif protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein); tripartite motif protein 8
Orthologs:
Homo sapiens (human) : TRIM8 (tripartite motif containing 8)  HGNC  Alliance
Mus musculus (house mouse) : Trim8 (tripartite motif-containing 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trim8 (tripartite motif containing 8)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIM8 (tripartite motif containing 8)
Canis lupus familiaris (dog) : TRIM8 (tripartite motif containing 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trim8 (tripartite motif containing 8)
Sus scrofa (pig) : TRIM8 (tripartite motif containing 8)
Chlorocebus sabaeus (African green monkey) : TRIM8 (tripartite motif containing 8)
Heterocephalus glaber (naked mole-rat) : Trim8 (tripartite motif containing 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01266,255,797 - 266,270,694 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1266,255,797 - 266,270,694 (+)Ensembl
Rnor_5.01273,686,719 - 273,701,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,724,890 - 251,739,787 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11251,988,330 - 252,002,878 (+)NCBI
Celera1241,152,131 - 241,166,997 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Trim8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1585223
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.