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Gene: Trim8 (tripartite motif-containing 8) Rattus norvegicus
Symbol: Trim8
Name: tripartite motif-containing 8
Description: Predicted to have protein homodimerization activity. Predicted to be involved in several processes, including negative regulation of viral process; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of NF-kappaB transcription factor activity. Predicted to localize to the PML body and cytosol. Orthologous to human TRIM8 (tripartite motif containing 8); INTERACTS WITH (+)-schisandrin B; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC308181; LOC688785; probable E3 ubiquitin-protein ligase TRIM8; similar to Tripartite motif protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein); tripartite motif protein 8
Homo sapiens (human) : TRIM8 (tripartite motif containing 8)  HGNC  Alliance
Mus musculus (house mouse) : Trim8 (tripartite motif-containing 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trim8 (tripartite motif containing 8)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIM8 (tripartite motif containing 8)
Canis lupus familiaris (dog) : TRIM8 (tripartite motif containing 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trim8 (tripartite motif containing 8)
Sus scrofa (pig) : TRIM8 (tripartite motif containing 8)
Chlorocebus sabaeus (African green monkey) : TRIM8 (tripartite motif containing 8)
Heterocephalus glaber (naked mole-rat) : Trim8 (tripartite motif containing 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01266,255,797 - 266,270,694 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1266,255,797 - 266,270,694 (+)Ensembl
Rnor_5.01273,686,719 - 273,701,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,724,890 - 251,739,787 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11251,988,330 - 252,002,878 (+)NCBI
Celera1241,152,131 - 241,166,997 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Trim8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1585223
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.