Pgk1 (phosphoglycerate kinase 1) - Rat Genome Database

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Gene: Pgk1 (phosphoglycerate kinase 1) Rattus norvegicus
Analyze
Symbol: Pgk1
Name: phosphoglycerate kinase 1
RGD ID: 619878
Description: Enables ADP binding activity; ATP binding activity; and phosphoglycerate kinase activity. Involved in gluconeogenesis and glycolytic process. Located in cytosol. Human ortholog(s) of this gene implicated in hemolytic anemia and phosphoglycerate kinase 1 deficiency. Orthologous to human PGK1 (phosphoglycerate kinase 1); PARTICIPATES IN gluconeogenesis pathway; glycolysis pathway; hypoxia inducible factor pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC105265; Pgk
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X71,271,454 - 71,287,429 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX71,271,440 - 71,287,418 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX72,780,371 - 72,796,345 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X76,280,383 - 76,296,357 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X73,843,195 - 73,859,169 (+)NCBIRnor_WKY
Rnor_6.0X77,263,399 - 77,279,373 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX77,263,359 - 77,279,367 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X56,383,459 - 56,399,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X94,324,219 - 94,340,193 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X94,397,574 - 94,413,625 (+)NCBI
CeleraX72,583,654 - 72,599,628 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(Z)-3-butylidenephthalide  (ISO)
1,10-phenanthroline  (ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-naphthoflavone  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
amphotericin B  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
Azaspiracid  (ISO)
azoxystrobin  (EXP)
beauvericin  (ISO)
benzatropine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorohydrocarbon  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clobetasol  (ISO)
clozapine  (EXP)
cobalt dichloride  (EXP,ISO)
cobalt(2+) sulfate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
deguelin  (ISO)
delphinidin  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dihydroartemisinin  (ISO)
dimercaprol  (ISO)
dioxygen  (EXP,ISO)
diuron  (EXP)
dopamine  (EXP)
doxorubicin  (ISO)
enniatin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenoldopam  (EXP)
ferric ammonium citrate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (EXP,ISO)
gentamycin  (EXP)
glyphosate  (EXP,ISO)
graphite  (ISO)
haloperidol  (EXP)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
imidacloprid  (EXP)
ivermectin  (ISO)
lithocholic acid  (ISO)
menadione  (ISO)
methamphetamine  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
miconazole  (ISO)
Monobutylphthalate  (ISO)
motexafin gadolinium  (ISO)
Muraglitazar  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (ISO)
nitrofen  (EXP)
ochratoxin A  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phenylpropanolamine  (ISO)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
prostaglandin A1  (ISO)
quartz  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
Salinomycin  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
Soman  (EXP)
sunitinib  (ISO)
T-2 toxin  (EXP)
tamoxifen  (EXP,ISO)
temozolomide  (ISO)
Tesaglitazar  (EXP)
tetraethylenepentamine  (ISO)
thapsigargin  (ISO)
thiabendazole  (EXP)
thimerosal  (ISO)
trimellitic anhydride  (ISO)
Triptolide  (ISO)
trovafloxacin  (EXP)
tungsten  (ISO)
tunicamycin  (ISO)
undecane  (EXP)
valproic acid  (ISO)
vandetanib  (ISO)
vorinostat  (ISO)
Yessotoxin  (ISO)
zearalenone  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IDA,ISO)
extracellular space  (ISO)
membrane raft  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Key enzymes of carbohydrate metabolism as targets of the 11.5-kDa Zn(2+)-binding protein (parathymosin). Brand IA and Heinickel A, J Biol Chem. 1991 Nov 5;266(31):20984-9.
2. Cloning and cDNA sequence of the rat X-chromosome linked phosphoglycerate kinase. Ciccarese S, etal., Biochem Biophys Res Commun 1989 Dec 29;165(3):1337-44.
3. Phosphoglycerate kinase deficiency: another cause of recurrent myoglobinuria. DiMauro S, etal., Ann Neurol. 1983 Jan;13(1):11-9.
4. The identification of a recurrent phosphoglycerate kinase mutation associated with chronic haemolytic anaemia and neurological dysfunction in a family from USA. Flanagan JM, etal., Br J Haematol. 2006 Jul;134(2):233-7. Epub 2006 Jun 1.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
7. Influence of beta,gamma-methyleneadenosine 5'-triphosphate and 2-phosphoglycerate on rat liver phosphoglycerate kinase. Lavoinne A Biochimie. 1986 Apr;68(4):569-74.
8. Kinetic studies of the reaction mechanism of rat liver phosphoglycerate kinase in the direction of ADP utilization. Lavoinne A, etal., Biochimie. 1983 Mar;65(3):211-20.
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceraldehyde-3-phosphate dehydrogenase. Sakai A, etal., Chem Res Toxicol. 2005 Feb;18(2):277-82.
18. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:943046   PMID:5009693   PMID:6852525   PMID:7391028   PMID:11130727   PMID:11487543   PMID:15277470   PMID:15489334   PMID:15665293   PMID:17248765   PMID:19199708   PMID:19946888  
PMID:20458337   PMID:21492153   PMID:22082260   PMID:22420779   PMID:22871113   PMID:23376485   PMID:23533145   PMID:23904609   PMID:25204797   PMID:26316108   PMID:29476059   PMID:32357304  


Genomics

Comparative Map Data
Pgk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X71,271,454 - 71,287,429 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX71,271,440 - 71,287,418 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX72,780,371 - 72,796,345 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X76,280,383 - 76,296,357 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X73,843,195 - 73,859,169 (+)NCBIRnor_WKY
Rnor_6.0X77,263,399 - 77,279,373 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX77,263,359 - 77,279,367 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X56,383,459 - 56,399,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X94,324,219 - 94,340,193 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X94,397,574 - 94,413,625 (+)NCBI
CeleraX72,583,654 - 72,599,628 (+)NCBICelera
Cytogenetic MapXq22NCBI
PGK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X78,104,248 - 78,129,295 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX77,910,739 - 78,129,295 (+)EnsemblGRCh38hg38GRCh38
GRCh37X77,359,745 - 77,384,792 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X77,246,425 - 77,268,980 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X77,165,913 - 77,188,467NCBI
CeleraX77,600,747 - 77,623,405 (+)NCBICelera
Cytogenetic MapXq21.1NCBI
HuRefX70,945,945 - 70,968,603 (+)NCBIHuRef
CHM1_1X77,252,363 - 77,275,021 (+)NCBICHM1_1
T2T-CHM13v2.0X76,539,329 - 76,564,376 (+)NCBIT2T-CHM13v2.0
Pgk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X105,230,706 - 105,247,305 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX105,230,706 - 105,247,305 (+)EnsemblGRCm39 Ensembl
GRCm38X106,187,100 - 106,203,699 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX106,187,100 - 106,203,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X103,382,463 - 103,399,038 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X102,389,843 - 102,406,418 (+)NCBIMGSCv36mm8
CeleraX93,040,533 - 93,057,028 (+)NCBICelera
Cytogenetic MapXDNCBI
cM MapX47.36NCBI
Pgk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555571,566,534 - 1,584,799 (+)NCBIChiLan1.0ChiLan1.0
PGK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X77,391,639 - 77,413,786 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX77,391,805 - 77,414,459 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X67,280,269 - 67,302,307 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PGK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X60,374,743 - 60,396,244 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX60,374,754 - 60,423,947 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX51,387,842 - 51,409,348 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X61,613,473 - 61,634,977 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX61,613,477 - 61,690,699 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X59,319,607 - 59,341,115 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X60,929,381 - 60,951,098 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X60,517,684 - 60,539,186 (+)NCBIUU_Cfam_GSD_1.0
Pgk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X53,965,864 - 53,989,650 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936547286,267 - 310,062 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX62,187,434 - 62,210,705 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X62,187,472 - 62,210,321 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X71,339,754 - 71,351,768 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig CytomapXq1.2NCBI
PGK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X67,072,029 - 67,093,881 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606714,418,994 - 14,440,951 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248362,653,474 - 2,676,766 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248362,657,320 - 2,676,124 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
AA892797  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map2206.3UniSTS
Cytogenetic MapXq31UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:282
Count of miRNA genes:186
Interacting mature miRNAs:211
Transcripts:ENSRNOT00000003390
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 6 4 4 4 3 2
Medium 3 37 53 37 19 37 8 8 72 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000077604   ⟹   ENSRNOP00000073523
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX71,271,440 - 71,287,418 (+)Ensembl
Rnor_6.0 EnsemblX77,263,359 - 77,279,367 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085653   ⟹   ENSRNOP00000073614
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX71,277,726 - 71,287,418 (+)Ensembl
Rnor_6.0 EnsemblX77,278,240 - 77,279,367 (+)Ensembl
RefSeq Acc Id: NM_053291   ⟹   NP_445743
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X71,271,454 - 71,287,429 (+)NCBI
Rnor_6.0X77,263,399 - 77,279,373 (+)NCBI
Rnor_5.0X56,383,459 - 56,399,433 (+)NCBI
RGSC_v3.4X94,324,219 - 94,340,193 (+)RGD
CeleraX72,583,654 - 72,599,628 (+)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_445743   ⟸   NM_053291
- UniProtKB: Q6P508 (UniProtKB/Swiss-Prot),   P16617 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073614   ⟸   ENSRNOT00000085653
RefSeq Acc Id: ENSRNOP00000073523   ⟸   ENSRNOT00000077604

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16617-F1-model_v2 AlphaFold P16617 1-417 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701902
Promoter ID:EPDNEW_R12426
Type:initiation region
Name:Pgk1_1
Description:phosphoglycerate kinase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X77,263,359 - 77,263,419EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619878 AgrOrtholog
BioCyc Gene G2FUF-1918 BioCyc
BioCyc Pathway ANAGLYCOLYSIS-PWY [glycolysis III (from glucose)] BioCyc
  PWY66-399 [gluconeogenesis III] BioCyc
Ensembl Genes ENSRNOG00000058249 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000073523 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000073614.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077604 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000085653.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Phosphoglycerate_kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphoglycerate_kinase_CS UniProtKB/Swiss-Prot
  Phosphoglycerate_kinase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphoglycerate_kinase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24644 UniProtKB/Swiss-Prot
NCBI Gene 24644 ENTREZGENE
PANTHER PTHR11406 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PGK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pgk1 PhenoGen
PIRSF Pgk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PHGLYCKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PGLYCERATE_KINASE UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53748 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MJL6_RAT UniProtKB/TrEMBL
  P16617 ENTREZGENE, UniProtKB/Swiss-Prot
  Q6P508 ENTREZGENE
UniProt Secondary Q5M945 UniProtKB/Swiss-Prot
  Q6P508 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Pgk1  phosphoglycerate kinase 1      Symbol and Name updated 629477 APPROVED
2003-03-06 Pgk1  phosphoglycerate kinase 1  Pgk  Phosphoglycerate kinase 1  Data Merged 628472 PROVISIONAL
2002-08-07 Pgk1        Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Pgk  Phosphoglycerate kinase 1      Symbol and Name status set to approved 70586 APPROVED