PGK1 (phosphoglycerate kinase 1) - Rat Genome Database

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Gene: PGK1 (phosphoglycerate kinase 1) Canis lupus familiaris
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Symbol: PGK1
Name: phosphoglycerate kinase 1
RGD ID: 12242498
Description: ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); phosphoglycerate kinase activity (ortholog); INVOLVED IN gluconeogenesis (ortholog); glycolytic process (ortholog); negative regulation of acetyl-CoA biosynthetic process from pyruvate (ortholog); PARTICIPATES IN gluconeogenesis pathway; glycolysis pathway; hypoxia inducible factor pathway; ASSOCIATED WITH alpha thalassemia-X-linked intellectual disability syndrome (ortholog); autistic disorder (ortholog); autosomal hemophilia A (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X60,374,743 - 60,396,244 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX60,374,754 - 60,423,947 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX51,387,842 - 51,409,348 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X61,613,473 - 61,634,977 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX61,613,477 - 61,690,699 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X59,319,607 - 59,341,115 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X60,929,381 - 60,951,098 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X60,517,684 - 60,539,186 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PGK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X60,374,743 - 60,396,244 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX60,374,754 - 60,423,947 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX51,387,842 - 51,409,348 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X61,613,473 - 61,634,977 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX61,613,477 - 61,690,699 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X59,319,607 - 59,341,115 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X60,929,381 - 60,951,098 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X60,517,684 - 60,539,186 (+)NCBIUU_Cfam_GSD_1.0
PGK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X78,104,248 - 78,129,295 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX77,910,739 - 78,129,295 (+)EnsemblGRCh38hg38GRCh38
GRCh37X77,359,745 - 77,384,792 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X77,246,425 - 77,268,980 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X77,165,913 - 77,188,467NCBI
CeleraX77,600,747 - 77,623,405 (+)NCBICelera
Cytogenetic MapXq21.1NCBI
HuRefX70,945,945 - 70,968,603 (+)NCBIHuRef
CHM1_1X77,252,363 - 77,275,021 (+)NCBICHM1_1
T2T-CHM13v2.0X76,539,329 - 76,564,376 (+)NCBIT2T-CHM13v2.0
Pgk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X105,230,706 - 105,247,305 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX105,230,706 - 105,247,305 (+)EnsemblGRCm39 Ensembl
GRCm38X106,187,100 - 106,203,699 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX106,187,100 - 106,203,699 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X103,382,463 - 103,399,038 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X102,389,843 - 102,406,418 (+)NCBIMGSCv36mm8
CeleraX93,040,533 - 93,057,028 (+)NCBICelera
Cytogenetic MapXDNCBI
cM MapX47.36NCBI
Pgk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X75,336,988 - 75,352,962 (+)NCBIGRCr8
mRatBN7.2X71,271,454 - 71,287,429 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX71,271,440 - 71,287,418 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX72,780,371 - 72,796,345 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X76,280,383 - 76,296,357 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X73,843,195 - 73,859,169 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X77,263,399 - 77,279,373 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX77,263,359 - 77,279,367 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X56,383,459 - 56,399,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X94,324,219 - 94,340,193 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X94,397,574 - 94,413,625 (+)NCBI
CeleraX72,583,654 - 72,599,628 (+)NCBICelera
Cytogenetic MapXq22NCBI
Pgk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555571,566,534 - 1,584,799 (+)NCBIChiLan1.0ChiLan1.0
PGK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X77,679,278 - 77,701,483 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X77,682,484 - 77,708,088 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X67,280,269 - 67,302,307 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X77,391,639 - 77,413,786 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX77,391,805 - 77,414,459 (+)Ensemblpanpan1.1panPan2
Pgk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X53,965,864 - 53,989,650 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936547286,267 - 310,062 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936547286,267 - 310,062 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX62,187,434 - 62,210,705 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X62,187,472 - 62,210,321 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X71,339,754 - 71,351,768 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig CytomapXq1.2NCBI
PGK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X67,072,029 - 67,093,881 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606714,418,994 - 14,440,951 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248362,653,474 - 2,676,766 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248362,657,320 - 2,676,124 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PGK1
101 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000027362   ⟹   ENSCAFP00000025449
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX60,374,754 - 60,395,960 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000083119   ⟹   ENSCAFP00000064249
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX60,374,754 - 60,423,947 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845036592   ⟹   ENSCAFP00845028635
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX61,613,477 - 61,634,973 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845036661   ⟹   ENSCAFP00845028696
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX61,613,512 - 61,690,699 (+)Ensembl
RefSeq Acc Id: XM_038450348   ⟹   XP_038306276
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X61,613,473 - 61,634,977 (+)NCBI
RefSeq Acc Id: XM_038523814   ⟹   XP_038379742
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X59,319,607 - 59,341,115 (+)NCBI
RefSeq Acc Id: XM_038587778   ⟹   XP_038443706
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X60,517,684 - 60,539,186 (+)NCBI
RefSeq Acc Id: XM_038652304   ⟹   XP_038508232
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X60,929,381 - 60,951,098 (+)NCBI
RefSeq Acc Id: XM_844899   ⟹   XP_849992
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X60,374,743 - 60,396,244 (+)NCBI
Dog10K_Boxer_TashaX51,387,842 - 51,409,348 (+)NCBI
Sequence:
RefSeq Acc Id: XP_849992   ⟸   XM_844899
- UniProtKB: A0A8C0SZN8 (UniProtKB/TrEMBL),   A0A8C0LKW3 (UniProtKB/TrEMBL),   A0A8I3P9Y9 (UniProtKB/TrEMBL),   A0A8I3PEK9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000064249   ⟸   ENSCAFT00000083119
Ensembl Acc Id: ENSCAFP00000025449   ⟸   ENSCAFT00000027362
RefSeq Acc Id: XP_038379742   ⟸   XM_038523814
RefSeq Acc Id: XP_038508232   ⟸   XM_038652304
RefSeq Acc Id: XP_038306276   ⟸   XM_038450348
- UniProtKB: A0A8C0SZN8 (UniProtKB/TrEMBL),   A0A8C0LKW3 (UniProtKB/TrEMBL),   A0A8I3P9Y9 (UniProtKB/TrEMBL),   A0A8I3PEK9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038443706   ⟸   XM_038587778
- UniProtKB: A0A8C0LKW3 (UniProtKB/TrEMBL),   A0A8C0SZN8 (UniProtKB/TrEMBL),   A0A8I3P9Y9 (UniProtKB/TrEMBL),   A0A8I3PEK9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845028696   ⟸   ENSCAFT00845036661
Ensembl Acc Id: ENSCAFP00845028635   ⟸   ENSCAFT00845036592

Promoters
RGD ID:13689367
Promoter ID:EPDNEW_C7435
Type:initiation region
Name:PGK1_1
Description:phosphoglycerate kinase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X60,374,771 - 60,374,831EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017270 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030009967 UniProtKB/TrEMBL
  ENSCAFG00040017144 UniProtKB/TrEMBL
  ENSCAFG00845020758 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000027362.5 UniProtKB/TrEMBL
  ENSCAFT00030018426.1 UniProtKB/TrEMBL
  ENSCAFT00030018531.1 UniProtKB/TrEMBL
  ENSCAFT00040031663.1 UniProtKB/TrEMBL
  ENSCAFT00040031761.1 UniProtKB/TrEMBL
  ENSCAFT00040031855.1 UniProtKB/TrEMBL
  ENSCAFT00040031902.1 UniProtKB/TrEMBL
  ENSCAFT00845036592.1 UniProtKB/TrEMBL
  ENSCAFT00845036661 ENTREZGENE
  ENSCAFT00845036661.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1260 UniProtKB/TrEMBL
InterPro Phosphoglycerate_kinase UniProtKB/TrEMBL
  Phosphoglycerate_kinase_CS UniProtKB/TrEMBL
  Phosphoglycerate_kinase_N UniProtKB/TrEMBL
  Phosphoglycerate_kinase_sf UniProtKB/TrEMBL
KEGG Report cfa:480964 UniProtKB/TrEMBL
NCBI Gene PGK1 ENTREZGENE
PANTHER PHOSPHOGLYCERATE KINASE 1 UniProtKB/TrEMBL
  PTHR11406 UniProtKB/TrEMBL
Pfam PGK UniProtKB/TrEMBL
PIRSF Pgk UniProtKB/TrEMBL
PRINTS PHGLYCKINASE UniProtKB/TrEMBL
PROSITE PGLYCERATE_KINASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53748 UniProtKB/TrEMBL
UniProt A0A8C0LKW3 ENTREZGENE
  A0A8C0MY08_CANLF UniProtKB/TrEMBL
  A0A8C0SZN8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SZV4_CANLF UniProtKB/TrEMBL
  A0A8C0Z0D9_CANLF UniProtKB/TrEMBL
  A0A8C0Z0K4_CANLF UniProtKB/TrEMBL
  A0A8I3P9Y9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PEK9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:49941 ENTREZGENE