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Gene: CLIC1 (chloride intracellular channel 1) Homo sapiens
Symbol: CLIC1
Name: chloride intracellular channel 1
Description: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chloride channel ABP; chloride intracellular channel protein 1; CL1C1; CLCNL1; G6; hRNCC; NCC27; nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64CLCP; regulatory nuclear chloride ion channel protein; RNCC protein
Mus musculus (house mouse) : Clic1 (chloride intracellular channel 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clic1 (chloride intracellular channel 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clic1 (chloride intracellular channel 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLIC1 (chloride intracellular channel 1)
Canis lupus familiaris (dog) : CLIC1 (chloride intracellular channel 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clic1 (chloride intracellular channel 1)
Sus scrofa (pig) : CLIC1 (chloride intracellular channel 1)
more info ...
Related Pseudogenes: CLIC1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38631,730,581 - 31,737,318 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37631,698,358 - 31,705,095 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,806,337 - 31,812,320 (-)NCBINCBI36hg18NCBI36
Build 34631,806,338 - 31,812,320NCBI
Celera633,296,583 - 33,302,566 (-)NCBI
Cytogenetic Map6p21.33NCBI
HuRef631,484,582 - 31,490,568 (-)NCBIHuRef
CHM1_1631,700,475 - 31,707,209 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CLIC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353337
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.