Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gdf6 (growth differentiation factor 6) Rattus norvegicus
Analyze
Symbol: Gdf6
Name: growth differentiation factor 6
Description: Predicted to have cytokine activity; protein homodimerization activity; and transforming growth factor beta receptor binding activity. Predicted to be involved in several processes, including positive regulation of cell differentiation; positive regulation of protein phosphorylation; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Klippel-Feil syndrome; Leber congenital amaurosis 17; cleft lip; isolated microphthalmia 4; and multiple synostoses syndrome. Orthologous to human GDF6 (growth differentiation factor 6); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH ammonium chloride; beta-naphthoflavone; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BMP-13; bone morphogenetic protein 13; GDF-6; gdf16; growth differentiation factor 16; growth/differentiation factor 16; growth/differentiation factor 6
Orthologs:
Homo sapiens (human) : GDF6 (growth differentiation factor 6)  HGNC  Alliance
Mus musculus (house mouse) : Gdf6 (growth differentiation factor 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf6 (growth differentiation factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF6 (growth differentiation factor 6)
Canis lupus familiaris (dog) : GDF6 (growth differentiation factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf6 (growth differentiation factor 6)
Sus scrofa (pig) : GDF6 (growth differentiation factor 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0523,056,345 - 23,072,666 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl523,056,347 - 23,074,599 (+)Ensembl
Rnor_5.0527,786,775 - 27,803,096 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4523,739,175 - 23,756,140 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1523,755,784 - 23,755,986 (+)NCBI
Celera522,249,415 - 22,265,738 (+)NCBICelera
Cytogenetic Map5q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Gdf6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620104
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.