Niddm10 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Niddm10 (Non-insulin dependent diabetes mellitus QTL 10) Rattus norvegicus

Symbol: Niddm10
Name: Non-insulin dependent diabetes mellitus QTL 10
RGD ID: 61462
Previously known as: Nidd/gk4; Non-insulin dependent diabetes mellitus GK QTL 4
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: plasma glucose level   (CMO:0000042)    
LOD Score: 3.9
P Value: 0.001
Variance: 11.0
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr851 - 9,895,442RGD_MAPPER_PIPELINE
mRatBN7.255,112,159 - 47,171,491RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.054,525,738 - 47,978,104RGD_MAPPER_PIPELINERnor6.0
Rnor_5.054,498,411 - 57,407,155RGDRnor5.0
RGSC_v3.454,291,144 - 49,586,522RGDRGSC3.4
RGSC_v3.150 - 4,291,301RGD
Cross Type: F2
Strains Crossed: GK/KyoSwe BN 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm10Rattype 2 diabetes mellitus  IDA 61061 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm10Ratimpaired glucose tolerance  QTM 61061 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm10Ratplasma glucose level  IDA 61061 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm10Ratfasting  IDA 61061 RGD 
Niddm10Ratglucose  IDA 61061 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm10Ratintravenous glucose tolerance test  IDA 61061 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm10RatBN  IEA 61061 RGD 
Niddm10RatGK/KyoSwe  IEA 61061 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Niddm10Ratblood glucose amount  IDA 61061 RGD 


#
Reference Title
Reference Citation
1. Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat Gauguier D, etal., Nat Genet 1996 Jan;12(1):38-43


1 to 20 of 314 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41204020LOC120102805uncharacterized LOC120102805550600945159282Rat
41046558LOC120102806uncharacterized LOC120102806553188005323393Rat
1584867Phb1-ps14prohibitin 1, pseudogene 14553298535331546Rat
40928183LOC120102807uncharacterized LOC120102807554355395438349Rat
1310557Rbpjl2recombination signal binding protein for immunoglobulin kappa J region-like 2554649695466367Rat
1359260Xkr9XK related 9555303845562168Rat
1307876Lactb2lactamase, beta 2555690805591843Rat
41087792LOC120102808uncharacterized LOC120102808555815695621082Rat
1359100Tram1translocation associated membrane protein 1556425795667666Rat
7520808LOC102548182uncharacterized LOC102548182556719475680129Rat
41205794Trnaa-agc87transfer RNA alanine (anticodon AGC) 87556893565689436Rat
41377667Ptmal6prothymosin alpha like 6557646715765429Rat
41210398LOC120103350small nucleolar RNA SNORA40558334695833590Rat
620108Ncoa2nuclear receptor coactivator 2558356426069693Rat
7488972Mir378bmicroRNA 378b559467235946806Rat
2319590Prdm14PR/SET domain 14560821636092712Rat
41152372LOC120103198U6 spliceosomal RNA562025226202625Rat
1307132Slco5a1solute carrier organic anion transporter family, member 5A1562289386358124Rat
708554Sulf1sulfatase 1563628946526174Rat
41380053LOC120102810uncharacterized LOC120102810564548746457731Rat

1 to 20 of 314 rows
1 to 20 of 422 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
34212D5Mgh517654372665643726832Ratregion
34387D5Mgh1721151452922514529436Ratregion
34469D5Mgh311952458344324583550Ratregion
34469D5Mgh311952458344324583550Ratregion
34469D5Mgh311952459887824598989Ratregion
34469D5Mgh311952459887824598989Ratregion
34481D5Mgh2814252483880224838943Ratregion
34599D5Mit1823251718969817189930Ratregion
34639D5Pas131052614166926141981Ratregion
36113D5Rat116253473011634730278Ratregion
36255D5Rat18913352381251823812651Ratregion
37596D5Rat118165559042635904428Ratregion
36618D5Rat216853793984237939998Ratregion
39756D5Rat12320751861599218616199Ratregion
39780D5Rat12718852660778426607972Ratregion
40414D5Rat20712552093858720938712Ratregion
40562D5Rat187176589482288948404Ratregion
40716D5Rat12410451887394718874051Ratregion
40718D5Rat120144581875018187645Ratregion
38548D5Rat8224654404503444045280Ratregion
1 to 20 of 422 rows

Peak: (D5Pas1)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2526,141,669 - 26,141,981 (+)MAPPER
Rnor_6.0526,251,767 - 26,252,076NCBI
Rnor_5.0530,952,629 - 30,952,938UniSTS
RGSC_v3.4526,938,679 - 26,938,988UniSTS
RGSC_v3.1526,938,678 - 26,938,989RGD
Celera525,460,475 - 25,460,784UniSTS
Flank 2: (D5Wox8)
Rat AssemblyChrPosition (strand)Source
GRCr859,895,285 - 9,895,442 (+)Marker Load Pipeline
mRatBN7.255,112,159 - 5,112,316 (+)MAPPER
Rnor_6.054,525,738 - 4,525,894NCBI
Rnor_5.054,498,411 - 4,498,567UniSTS
RGSC_v3.454,291,144 - 4,291,301RGD
RGSC_v3.454,291,145 - 4,291,301UniSTS
RGSC_v3.154,291,145 - 4,291,301RGD
Celera54,703,176 - 4,703,332UniSTS
RH 3.4 Map50.0RGD
RH 3.4 Map50.0UniSTS
RH 2.0 Map50.0RGD
Cytogenetic Map5 RGD


1 to 10 of 35 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat

1 to 10 of 35 rows


Database
Acc Id
Source(s)
NCBI Gene Niddm10


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-07-15 Niddm10  Non-insulin dependent diabetes mellitus QTL 10  Niddm10  Non-insulin dependent diabetes mellitus QTL 10  Name updated 68913 APPROVED
2004-09-08 Niddm10  Non-insulin-dependent diabetes mellitus QTL 10  Nidd/gk4  Non-insulin dependent diabetes mellitus GK QTL 4  Symbol and Name updated 1299863 APPROVED

Note Type Note Reference
qtl_cross_type intercross