Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cpne3 | Rat | 1,2-dichloroethane | increases expression | ISO | Cpne3 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of CPNE3 mRNA | CTD | PMID:28960355 | Cpne3 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Cpne3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CPNE3 mRNA | CTD | PMID:22206623 | Cpne3 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Cpne3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of CPNE3 mRNA | CTD | PMID:22206623 | Cpne3 | Rat | 1-chloro-2,4-dinitrobenzene | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Dinitrochlorobenzene results in decreased expression of CPNE3 mRNA | CTD | PMID:17374397 | Cpne3 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Cpne3 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of CPNE3 mRNA | CTD | PMID:17942748 | Cpne3 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Cpne3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CPNE3 mRNA | CTD | PMID:17942748 | Cpne3 | Rat | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of CPNE3 mRNA | CTD | PMID:32145629 | Cpne3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Cpne3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CPNE3 mRNA | CTD | PMID:17942748 | Cpne3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CPNE3 mRNA | CTD | PMID:33387578 | Cpne3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CPNE3 mRNA | CTD | PMID:34747641 | Cpne3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CPNE3 mRNA | CTD | PMID:32109520 | Cpne3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Cpne3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CPNE3 mRNA | CTD | PMID:21570461 | Cpne3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Cpne3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CPNE3 mRNA | CTD | PMID:19770486 | Cpne3 | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | [Furaldehyde co-treated with pyrogallol 1 more ... | CTD | PMID:38598786 | Cpne3 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of CPNE3 mRNA | CTD | PMID:21346803 | Cpne3 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of CPNE3 mRNA | CTD | PMID:28522335 | Cpne3 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Cpne3 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of CPNE3 mRNA | CTD | PMID:18648102 | Cpne3 | Rat | 4-(ethoxymethylene)-2-phenyloxazol-5-one | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Oxazolone results in decreased expression of CPNE3 mRNA | CTD | PMID:17374397 | Cpne3 | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of CPNE3 mRNA | CTD | PMID:28959563 | Cpne3 | Rat | antimycin A | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of CPNE3 mRNA | CTD | PMID:33512557 | Cpne3 | Rat | aristolochic acid A | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of CPNE3 mRNA | CTD | PMID:33212167 | Cpne3 | Rat | arsane | affects methylation | ISO | CPNE3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of CPNE3 gene | CTD | PMID:25304211 | Cpne3 | Rat | arsenic atom | affects methylation | ISO | CPNE3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of CPNE3 gene | CTD | PMID:25304211 | Cpne3 | Rat | benzatropine | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Benztropine results in decreased expression of CPNE3 protein | CTD | PMID:34122009 | Cpne3 | Rat | benzo[a]pyrene | decreases methylation | ISO | CPNE3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of CPNE3 5' UTR | CTD | PMID:27901495 | Cpne3 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 | Cpne3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CPNE3 mRNA | CTD | PMID:25181051 and PMID:33296240 | Cpne3 | Rat | bisphenol A | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of CPNE3 gene | CTD | PMID:31601247 | Cpne3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CPNE3 mRNA | CTD | PMID:34947998 | Cpne3 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CPNE3 mRNA | CTD | PMID:32145629 | Cpne3 | Rat | bisphenol AF | increases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of CPNE3 protein | CTD | PMID:34186270 | Cpne3 | Rat | Bisphenol B | increases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of CPNE3 protein | CTD | PMID:34186270 | Cpne3 | Rat | bisphenol F | increases expression | ISO | Cpne3 (Mus musculus) | 6480464 | bisphenol F results in increased expression of CPNE3 mRNA | CTD | PMID:38685157 | Cpne3 | Rat | bisphenol F | increases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of CPNE3 protein | CTD | PMID:34186270 | Cpne3 | Rat | cadmium atom | increases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Cadmium results in increased expression of CPNE3 mRNA | CTD | PMID:24376830 | Cpne3 | Rat | cadmium dichloride | decreases expression | ISO | Cpne3 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of CPNE3 mRNA | CTD | PMID:24982889 | Cpne3 | Rat | calciol | increases expression | ISO | Cpne3 (Mus musculus) | 6480464 | Cholecalciferol results in increased expression of CPNE3 mRNA | CTD | PMID:16508948 | Cpne3 | Rat | chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of CPNE3 mRNA | CTD | PMID:23125180 | Cpne3 | Rat | crocidolite asbestos | decreases expression | ISO | Cpne3 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of CPNE3 mRNA | CTD | PMID:29279043 | Cpne3 | Rat | cyclosporin A | decreases expression | ISO | Cpne3 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of CPNE3 mRNA | CTD | PMID:19770486 | Cpne3 | Rat | cyclosporin A | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of CPNE3 mRNA | CTD | PMID:25562108 | Cpne3 | Rat | deguelin | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | deguelin results in decreased expression of CPNE3 mRNA | CTD | PMID:33512557 | Cpne3 | Rat | dorsomorphin | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CPNE3 mRNA | CTD | PMID:27188386 | Cpne3 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CPNE3 mRNA | CTD | PMID:29391264 | Cpne3 | Rat | enzyme inhibitor | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CPNE3 protein | CTD | PMID:23301498 | Cpne3 | Rat | ethanol | increases expression | ISO | Cpne3 (Mus musculus) | 6480464 | Ethanol results in increased expression of CPNE3 mRNA | CTD | PMID:30319688 | Cpne3 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of CPNE3 mRNA | CTD | PMID:24136188 | Cpne3 | Rat | folic acid | multiple interactions | ISO | Cpne3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CPNE3 mRNA | CTD | PMID:22206623 | Cpne3 | Rat | formaldehyde | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of CPNE3 mRNA | CTD | PMID:23649840 | Cpne3 | Rat | fulvestrant | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of CPNE3 gene | CTD | PMID:31601247 | Cpne3 | Rat | furfural | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | [Furaldehyde co-treated with pyrogallol 1 more ... | CTD | PMID:38598786 | Cpne3 | Rat | geldanamycin | increases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of CPNE3 mRNA | CTD | PMID:26705709 | Cpne3 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of CPNE3 mRNA | CTD | PMID:33387578 | Cpne3 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of CPNE3 mRNA | CTD | PMID:24136188 | Cpne3 | Rat | haloperidol | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Haloperidol results in decreased expression of CPNE3 protein | CTD | PMID:34122009 | Cpne3 | Rat | ivermectin | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of CPNE3 protein | CTD | PMID:32959892 | Cpne3 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of CPNE3 mRNA | CTD | PMID:30467583 | Cpne3 | Rat | methylmercury chloride | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of CPNE3 mRNA | CTD | PMID:28001369 | Cpne3 | Rat | nickel sulfate | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of CPNE3 mRNA | CTD | PMID:17374397 | Cpne3 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CPNE3 mRNA | CTD | PMID:33387578 | Cpne3 | Rat | perfluorooctanoic acid | increases expression | ISO | Cpne3 (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of CPNE3 protein | CTD | PMID:37422089 | Cpne3 | Rat | SB 431542 | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CPNE3 mRNA | CTD | PMID:27188386 | Cpne3 | Rat | sodium arsenate | increases expression | ISO | Cpne3 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of CPNE3 mRNA | CTD | PMID:21795629 | Cpne3 | Rat | sodium arsenite | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [H3-3A protein binds to CPNE3 protein] | CTD | PMID:37734572 | Cpne3 | Rat | sodium arsenite | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of CPNE3 protein | CTD | PMID:30528433 | Cpne3 | Rat | sodium chloride | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of CPNE3 protein more ... | CTD | PMID:38598786 | Cpne3 | Rat | sunitinib | increases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of CPNE3 mRNA | CTD | PMID:31533062 | Cpne3 | Rat | tebufenpyrad | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of CPNE3 mRNA | CTD | PMID:33512557 | Cpne3 | Rat | testosterone enanthate | affects expression | ISO | CPNE3 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of CPNE3 mRNA | CTD | PMID:17440010 | Cpne3 | Rat | tetrachloromethane | decreases expression | ISO | Cpne3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of CPNE3 mRNA | CTD | PMID:31919559 | Cpne3 | Rat | thifluzamide | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | thifluzamide results in decreased expression of CPNE3 mRNA | CTD | PMID:33512557 | Cpne3 | Rat | thimerosal | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of CPNE3 mRNA | CTD | PMID:27188386 | Cpne3 | Rat | titanium dioxide | increases expression | ISO | Cpne3 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of CPNE3 mRNA | CTD | PMID:29264374 | Cpne3 | Rat | titanium dioxide | decreases methylation | ISO | Cpne3 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of CPNE3 gene and titanium dioxide results in decreased methylation of CPNE3 promoter alternative form | CTD | PMID:35295148 | Cpne3 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of CPNE3 mRNA | CTD | PMID:33387578 | Cpne3 | Rat | trichostatin A | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of CPNE3 mRNA | CTD | PMID:24935251 and PMID:26272509 | Cpne3 | Rat | trichostatin A | multiple interactions | ISO | CPNE3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CPNE3 mRNA | CTD | PMID:27188386 | Cpne3 | Rat | triphenyl phosphate | affects expression | ISO | CPNE3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of CPNE3 mRNA | CTD | PMID:37042841 | Cpne3 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of CPNE3 mRNA | CTD | PMID:30589522 | Cpne3 | Rat | triticonazole | increases expression | EXP | | 6480464 | triticonazole results in increased expression of CPNE3 mRNA | CTD | PMID:36084822 | Cpne3 | Rat | valproic acid | decreases methylation | ISO | CPNE3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of CPNE3 gene | CTD | PMID:29154799 | Cpne3 | Rat | valproic acid | increases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CPNE3 mRNA | CTD | PMID:19101580 | Cpne3 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of CPNE3 mRNA | CTD | PMID:23869203 | Cpne3 | Rat | vincristine | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of CPNE3 mRNA | CTD | PMID:23649840 | Cpne3 | Rat | vorinostat | decreases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of CPNE3 mRNA | CTD | PMID:27188386 | Cpne3 | Rat | zoledronic acid | increases expression | ISO | CPNE3 (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of CPNE3 mRNA | CTD | PMID:20977926 | |