Neudeg2 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Neudeg2 (Neurodegradation QTL 2) Rattus norvegicus

Symbol: Neudeg2
Name: Neurodegradation QTL 2
RGD ID: 1549901
Previously known as: Vra2
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: mononuclear cell count   (CMO:0002119)    
LOD Score: 4.0
P Value: 0.0
Variance: Not Available
Inheritance Type: additive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2524,838,710 - 44,045,280RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0524,956,212 - 44,747,071RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0529,676,862 - 49,366,257RGDRnor5.0
RGSC_v3.4525,602,274 - 45,822,846RGDRGSC3.4
RGSC_v3.1525,452,401 - 45,823,025RGD
Cross Type: Not Available
Strains Crossed: PVG/OlaHsd DA/Ztm 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Vertebrate Trait

Rat Strain
DA/Ztm  (IEA)
PVG/OlaHsd  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Discrete gene loci regulate neurodegeneration, lymphocyte infiltration, and major histocompatibility complex class II expression in the CNS. Lidman O, etal., J Neurosci 2003 Oct 29;23(30):9817-23.
2. Genetic dissection of neurodegeneration and CNS inflammation. Olsson T, etal., J Neurol Sci 2005 Jun 15;233(1-2):99-108.
3. Fine mapping of gene regions regulating neurodegeneration. Swanberg M, etal., PLoS One. 2009 Jun 15;4(6):e5906.
Related QTLs

Related QTL Description Reference
Neudeg1 interacts with RGD:2317162


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
61946Pou3f2POU class 3 homeobox 253607793036083838Rat
69340Calb1calbindin 152937562429402532Rat
619748Cdh17cadherin 1752526282025314884Rat
2682Gghgamma-glutamyl hydrolase53352988033552790Rat
2380Coq3coenzyme Q3 methyltransferase53542956735460613Rat
621420Nbnnibrin52945957429494152Rat
620199Mmp16matrix metallopeptidase 1653131228031556276Rat
70905Ccnccyclin C53526682835284943Rat
620327Maneamannosidase, endo-alpha54019637340218540Rat
1307056Fhl5four and a half LIM domains 553890794138956759Rat
70999Decr12,4-dienoyl-CoA reductase 152941117229439054Rat
735162Ndufaf4NADH:ubiquinone oxidoreductase complex assembly factor 453860516938610341Rat
3915Ttpaalpha tocopherol transfer protein53349753733518936Rat
708548Necab1N-terminal EF-hand calcium binding protein 152835785928578642Rat
620393Pdp1pyruvate dehydrogenase phosphatase catalytic subunit 152544684325455107Rat
70957Epha7Eph receptor A754297535343128703Rat
619955Fut9fucosyltransferase 953935181539565256Rat
1304693Mms22lMMS22-like, DNA repair protein53819770738313745Rat
1306323Osgin2oxidative stress induced growth inhibitor family member 252950040629519340Rat
1306900Atp6v0d2ATPase H+ transporting V0 subunit D253333625733385354Rat
1305724Fbxl4F-box and leucine-rich repeat protein 453595580136029446Rat
1307386GemGTP binding protein overexpressed in skeletal muscle52521430925225222Rat
1307395PnisrPNN interacting serine and arginine rich protein53539596535422852Rat
1306460Gpr63G protein-coupled receptor 6353867254838727224Rat
1310024Otud6bOTU deubiquitinase 6B52818199228214486Rat
1310178Cpne3copine 353301465833063934Rat
1310364Klhl32kelch-like family member 3253832123738568453Rat
1310846Slc26a7solute carrier family 26 member 752788440028021865Rat
1311633Slc7a13solute carrier family 7 member 1353327740033298186Rat
1310976Usp45ubiquitin specific peptidase 4553531862135392090Rat
1306507Rad54bRAD54 homolog B52503211225104630Rat
1305490Runx1t1RUNX1 partner transcriptional co-repressor 152718767427338070Rat
1306225Pip4p2phosphatidylinositol-4,5-bisphosphate 4-phosphatase 252825982128307225Rat
1309308Ufl1Ufm1-specific ligase 153896272138995134Rat
1307658Rbm12bRNA binding motif protein 12B52559740525610324Rat
1310681Cibar1CBY1 interacting BAR domain containing 152561399325632440Rat
1309167Ripk2receptor-interacting serine-threonine kinase 252963080629662804Rat
1311734Wwp1WW domain containing E3 ubiquitin protein ligase 153309237933185887Rat
1562449Faxcfailed axon connections homolog, metaxin like GST domain containing53548013735539741Rat
1563085Rmdn1regulator of microtubule dynamics 153307026733093922Rat
1562265Rps12l5ribosomal protein S12 like 554361252843612958Rat
1559904Virmavir like m6A methyltransferase associated52496120825024660Rat
1586167Tmem67transmembrane protein 6752553645825589378Rat
1586088Gabpb2-ps1GA binding protein transcription factor subunit beta 2, pseudogene 152959621329605030Rat
1585101Casp3-ps4caspase 3, pseudogene 453455824334559081Rat
1583733Lrrc69leucine rich repeat containing 6952802359128181963Rat
1563572Tstd3thiosulfate sulfurtransferase like domain containing 353529465235304093Rat
1586399Nsa2-ps10NSA2 ribosome biogenesis factor, pseudogene 1053789234137897149Rat
1565364Cngb3cyclic nucleotide gated channel subunit beta 353274698832995121Rat
1561260Triqktriple QxxK/R motif containing52639151126464422Rat
1565988Bhmt-ps1betaine-homocysteine S-methyltransferase, pseudogene 153036296530390524Rat
1592300Cnbd1cyclic nucleotide binding domain containing 153223400332606765Rat
1589883Prdm13PR/SET domain 1353522081535232866Rat
1589948Atp5po-ps1ATP synthase peripheral stalk subunit OSCP, pseudogene 153510828035108914Rat
1584049Arl6-ps1ADP-ribosylation factor like GTPase 6, pseudogene 154284114642841746Rat
1585166Slc25a36-ps1solute carrier family 25 member 36, pseudogene 154026254740295229Rat
1596128Tmem64transmembrane protein 6452869894728745384Rat
1597419Dnaja1-ps2DnaJ heat shock protein family (Hsp40) member A1, pseudogene 252781036927811537Rat
1593494Eif5-ps9eukaryotic translation initiation factor 5, pseudogene 953067638330677491Rat
1591051Nkain3Sodium/potassium transporting ATPase interacting 353361372034310090Rat
1593555Cnga4-ps1cyclic nucleotide gated channel subunit alpha 4, pseudogene 152971705229718455Rat
2318778Mrpl30-ps6mitochondrial ribosomal protein L30, pseudogene 652944778629448371Rat
2320072Eif5-ps4eukaryotic translation initiation factor 5, pseudogene 452514896325152683Rat
2318973Ppp1cc-ps1protein phosphatase 1 catalytic subunit gamma, pseudogene 153045623330458067Rat
2322518Dpy30-ps2dpy-30 histone methyltransferase complex regulatory subunit, pseudogene 254222778342228049Rat
2324327Pcnp-ps1PEST proteolytic signal containing nuclear protein, pseudogene 153584625835848205Rat
2324520Kat2b-ps1lysine acetyltransferase 2B, pseudogene 153542640735428184Rat
6487307C5h8orf88similar to human chromosome 8 open reading frame 8852833016728355691Rat
6492721LOC100911464glutathione S-transferase P-like53858666738592201Rat
6490958Rps6-ps1ribosomal protein S6, pseudogene 154031268240313404Rat
6495713Rps18-ps1ribosomal protein S18, pseudogene 153514547535145950Rat
7530658LOC102549334uncharacterized LOC10254933454369784143757417Rat
7513176LOC102553820uncharacterized LOC10255382053608558836089407Rat
7638920LOC102552309uncharacterized LOC10255230952515280525154273Rat
7611658Fsbpfibrinogen silencer binding protein52505800325064276Rat
7556989Ormdl1-ps2ORMDL sphingolipid biosynthesis regulator 1, pseudogene 253263950232645632Rat
7586726LOC102552692uncharacterized LOC10255269252567482125715582Rat
7708268LOC102553889uncharacterized LOC10255388952806173828076577Rat
7731407LOC102552377uncharacterized LOC10255237752527333925289529Rat
9225019LOC10369524660S ribosomal protein L39-like53864218238642839Rat
9302605LOC103692303uncharacterized LOC10369230352483066924855700Rat
9444073Hdac1-ps1histone deacetylase 1, pseudogene 153406494734076063Rat
11472967LOC10835112160S ribosomal protein L29 pseudogene52753782727538390Rat
11444056LOC108350937ferritin light chain 1 pseudogene52843074328431569Rat
11366942LOC10835108560S ribosomal protein L13 pseudogene53319174133201352Rat
11398785LOC10835112060S ribosomal protein L17 pseudogene52746049327461058Rat
11480254LOC108351124uncharacterized LOC10835112454378010443783053Rat
41322375LOC120102845uncharacterized LOC12010284553609136236095251Rat
41355203LOC120102838uncharacterized LOC12010283852966282929715416Rat
41277993Trnat-agu10transfer RNA threonine (anticodon AGU) 1052693417726934249Rat
41114922LOC120103328small nucleolar RNA SNORA1752751011927510246Rat
41358655Rpl6-ps2ribosomal protein L6, pseudogene 254259253142593424Rat
41253648LOC120103271small nucleolar RNA SNORA1552933447529334604Rat
41145764LOC120103388U6 spliceosomal RNA54068212540682231Rat
41208256LOC120103326small nucleolar RNA SNORA1752940795329408081Rat
41209789LOC120103334small nucleolar RNA SNORA1752765310727653215Rat
41388173Wsb1-ps1WD repeat and SOCS box-containing 1, pseudogene 152488168824891528Rat
41174538Tuba2l-ps1tubulin, alpha 2 like, pseudogene 152951187629518964Rat
41262738LOC120103208U6 spliceosomal RNA54304813943048245Rat
41100894LOC120102832RNA-binding protein 12B-A-like52559050025597273Rat
41101046LOC120102830uncharacterized LOC12010283052486926424872255Rat
41124986LOC120103374U4 spliceosomal RNA53356421533564342Rat
41102124Kpna1-ps1karyopherin subunit alpha 1, pseudogene 153044913630455949Rat
41102833LOC120103292small nucleolar RNA SNORA4853517650435176637Rat
41195959Runx1t1lRUNX1 partner transcriptional co-repressor 1 like52716768927188550Rat
41162947Rps20-ps9ribosomal protein S20, pseudogene 953880265738803367Rat
41294829LOC120103330small nucleolar RNA SNORA1754253603042536158Rat
41133959LOC120103304small nucleolar RNA SNORA1753928202539282156Rat
41166424LOC120103363U2 spliceosomal RNA52849750128497630Rat
40972884LOC120102833uncharacterized LOC12010283352646198526467263Rat
40956040Bex4-ps2brain expressed X-linked 4, pseudogene 252862147428684995Rat
40985493LOC120103329small nucleolar RNA SNORA1753599237635992505Rat
41006368LOC120103311U2 spliceosomal RNA54123388541233967Rat
40941923LOC120102836uncharacterized LOC12010283652871884128768110Rat
40944019LOC120103219U6 spliceosomal RNA53105101031051115Rat
40969773LOC120103351small nucleolar RNA SNORA2653828552538285644Rat
41074835LOC120103248U7 small nuclear RNA53878275638782820Rat
41243557Wee2-ps1WEE2 oocyte meiosis inhibiting kinase, pseudogene 153555171635553140Rat
41075750LOC120103316small nucleolar RNA SNORA1753460649634606629Rat
41312846LOC120103244U7 small nuclear RNA53215196932152031Rat
41134945LOC120102842uncharacterized LOC12010284253526381335266767Rat
41256844LOC120102846uncharacterized LOC12010284654308424543103773Rat
41335677LOC120103222U6 spliceosomal RNA53903012139030224Rat
41317448LOC120103335small nucleolar RNA SNORA1753887785038877982Rat
41032391Trnap-agg53transfer RNA proline (anticodon AGG) 5353214375232143824Rat
41222336Pym1-ps15PYM homolog 1, exon junction complex associated factor, pseudogene 1553314213433146238Rat
41222628LOC120102844uncharacterized LOC12010284453583956535843140Rat
41226688LOC120102835uncharacterized LOC12010283552755964727586169Rat
41301908Chtop-ps2chromatin target of PRMT1, pseudogene 252491451624919438Rat
41305661LOC120102841uncharacterized LOC12010284153514989835192551Rat
41307010LOC120103144uncharacterized LOC12010314452903259729047722Rat
41020351LOC120103356U6atac minor spliceosomal RNA52500862725008726Rat
41021982Rpl30-ps6ribosomal protein L30, pseudogene 653538183235382175Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34212D5Mgh518154372665643726832Ratregion
34481D5Mgh2812352483880224838943Ratregion
34639D5Pas131052614166926141981Ratregion
36113D5Rat116353473011634730278Ratregion
36618D5Rat216853793984237939998Ratregion
39780D5Rat12719852660778426607972Ratregion
38548D5Rat8224054404503444045280Ratregion
40330D5Rat13014553166378931663928Ratregion
39160D5Rat7323752483871024838943Ratregion
39186D5Rat7024953518915335189418Ratregion
42190D5Arb1823452972406229724324Ratregion
42314D5Rat25023853370151833701740Ratregion
42315D5Rat25120453675380236754006Ratregion
42737D5Rat19122553556320335563429Ratregion
42738D5Rat22020253348711933487295Ratregion
41350D5Rat13215254012830740128459Ratregion
43891D6Got3620253566775035667952Ratregion
60623D8Got2521552849399828494213Ratregion
60493D5Got7218753869621938696406Ratregion
69546D5Uwm1215752726873627268904Ratregion
69548D5Uwm1320253725264437252890Ratregion
69553D5Uwm5119753335046833350661Ratregion
66662D5Mco2532653387800433878321Ratregion
67219D5Arb2217852801325928013437Ratregion
67360D5Arb1653548860835488977Ratregion
1630361D5Got21111952686519226865311Ratregion
1630371D5Got27411153343667833436775Ratregion
1630875D5Wox3620953154736731547578Ratregion
1631146D5Got2799453675392036754014Ratregion
1631457D5Got28810453167064431670743Ratregion
1631662D5Got28117353298018732980360Ratregion
1632343D5Got21716253875440738754569Ratregion
1578970D10Chm5117053358383633584012Ratregion
1579025D10Chm5025053366817233668415Ratregion
1628972D5Got28912953841574038415871Ratregion
1629157D5Got21314552748649727486644Ratregion
1629836D5Got26511253648516436485271Ratregion
1638832D5Got31613453491089434911028Ratregion
1638832D5Got31613453491092534911028Ratregion
1633482D5Got21515853683371036833869Ratregion
1633616D5Got27518353556330135563484Ratregion
1640375D5Got21614153409119634091337Ratregion
1635256D5Got21430053473312534733425Ratregion
1636412D5Got29827553559128735591566Ratregion
1636547D5Got21918253830759438307778Ratregion
1636727D5Got28426554229729842297686Ratregion
1636727D5Got28426554229742142297686Ratregion
1638167D5Got28514652787870427878850Ratregion
1638216D5Got22015354156573941565892Ratregion
1634531D3Got2729252491974524919836Ratregion
1634714D5Got28314353196981631969954Ratregion
7193019Runx1t142252733408227334504Ratregion
7206292Pou3f273053608272336083453Ratregion
5035809PMC196070P122453608358836083812Ratregion
5035961PMC317216P177053608217036082940Ratregion
5036173RH12567627453510827135108545Ratregion
7206540UniSTS:546979105952733419327335253Ratregion
7206622Pou3f253153608319836083729Ratregion
5036460Pou3f218853608327636083464Ratregion
5036829AU04933724552993213229932377Ratregion
5037167RH8046023852733784327338081Ratregion
5033857RH14037820953896205638962265Ratregion
5031468AU04822314954096515940965308Ratregion
5034009RH14101319852847366028473859Ratregion
5034009RH14101319852847366028473859Ratregion
5034121RH14144319652646405926464255Ratregion
5034309Epha721154312546543125676Ratregion
5026468RH13232622052544686625447086Ratregion
5026582RH13276522052963087829631098Ratregion
5032207AB02122814353154710131547244Ratregion
5035146BQ20049115953315944233159602Ratregion
5029865AW53093718452948600629486190Ratregion
5032679RH13489515653333540333335559Ratregion
5027263AV00136011952830693728307056Ratregion
5032795RH13532620554019709940197304Ratregion
5035310BM38627220952950116729501376Ratregion
5030215AW53231315953136060031360759Ratregion
5024984AW5515838553896384438963929Ratregion
5027725D8S195010652733459727334703Ratregion
5030845BE12064218753847622538476411Ratregion
5030879BE11445819453155310731553301Ratregion
5025846RH12991321353602912136029334Ratregion
5025848RH12992121753528459035284807Ratregion
5028430D2635214152939924629399387Ratregion
5051140RH13446218053154975531549935Ratregion
5055999RH14412411653742990837430024Ratregion
5056045RH14415123552952046329520698Ratregion
5053933RH14293422353313259833132821Ratregion
5055081RH14359518054297633142976511Ratregion
5056267RH14428028653935928539359571Ratregion
5058822BI28467721653528189835282114Ratregion
5056637RH14449318252963164929631831Ratregion
5056965RH14468220252729158627291788Ratregion
5054055RH14300414753871339638713543Ratregion
5051148RH13446720653700917437009380Ratregion
5051362AU01508411253532066535320777Ratregion
5053261RH14254614754312826943128416Ratregion
5044082RH13039918052559691725597097Ratregion
5043352RH12997718153528464035284821Ratregion
5045768RH13136818453595437935954563Ratregion
5044796RH13080820052871843928718639Ratregion
5046348RH13170118452819745628197637Ratregion
5046460RH13176521653522084435221060Ratregion
5045272RH13108319653546031235460508Ratregion
5047160RH13216821853309804133098259Ratregion
5047380RH13229418053935185639352036Ratregion
5042418RH12942320753598652235986729Ratregion
5039710RH12786220252830682928307031Ratregion
5040128RH12810520153487805234878251Ratregion
5040942RH12857219252940091929401111Ratregion
5041474RH12887718652830571728305903Ratregion
5072486RH13687722053542246935422689Ratregion
5072322RH13678216852553659425536762Ratregion
5076594RH13926624553379142133791666Ratregion
5076718RH13933812353301506633015189Ratregion
5077338RH13969920952940045829400667Ratregion
5077540RH13981519552561375325613948Ratregion
5079854RH14124118053461769034617772Ratregion
5070874RH13475518652788457427884760Ratregion
5073320RH13736821953538909435389313Ratregion
5073320RH13736821953538909435389313Ratregion
5071818RH13530219253329973233299924Ratregion
5074170RH13786224752554118625541433Ratregion
5074414RH13800318953953867939538868Ratregion
5074756RH13820020453746788837468092Ratregion
5067652AU04761617953775332237753498Ratregion
5068046AU04738013052659820426598334Ratregion
5068764AU04694610353320751133207609Ratregion
5069476AU04647328453856403538564319Ratregion
5070352AI8431919753538896535389062Ratregion
5070352AI8431919753538896535389062Ratregion
5069098AU04672618653568341135683599Ratregion
5063702BF40456411553397389033974005Ratregion
5065242BE12126316453307081333070977Ratregion
5065472BE11560616853154818231548350Ratregion
5064612BF39943716153537196735372128Ratregion
5061274BE11142016353650291136503074Ratregion
5063210BI30142517453520216435202338Ratregion
5061534BE10540820653608848636088692Ratregion
5087098BQ20908921552637680726377022Ratregion
5087722Cbfa2t1h19652733498927335185Ratregion
5087506PMC212738P149353547718935477365Ratregion
5089851AU04940021453675697036757184Ratregion
5083159BI27522013252553716725537299Ratregion
5087983UniSTS:143722053045590230456083Ratregion
5088897AU04883412853432437934324507Ratregion
5081156RH14199721953747585437476073Ratregion
5086238BQ19200018153155454131554721Ratregion
5085701BM39079018253930125339301435Ratregion
5086687BE10725818152726543827265620Ratregion
5081965BE11893315052724500227245152Ratregion
5504340D11S303847852685165926852137Ratregion
5504928Runx1t15252733519227335244Ratregion
5504873ha284791354211235542113268Ratregion
5505052Kat2b6853542712335427190Ratregion
5505748UniSTS:492577144853608237636083824Ratregion
5506007UniSTS:49727763854284112642841764Ratregion
5506463GDB:13175647852592491925924997Ratregion
5506553MMP16_92090953154693031547841Ratregion
5507101UniSTS:22453919754310892343109120Ratregion
5507181UniSTS:22501415152733436227334513Ratregion
5499527stSG60954810052858531728585417Ratregion
5499825UniSTS:23487222352830697528307198Ratregion
5503017Fut941653936313039363546Ratregion
5501722UniSTS:26699014254312507543125217Ratregion
5501848MARC_15705-15706:1013524302:116452491660224916766Ratregion
Position Markers

Flank 1: (D5Rat73)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2524,838,710 - 24,838,943 (+)MAPPER
Rnor_6.0524,956,212 - 24,956,444NCBI
Rnor_5.0529,676,862 - 29,677,094UniSTS
RGSC_v3.4525,602,274 - 25,602,507RGD
RGSC_v3.4525,602,275 - 25,602,507UniSTS
RGSC_v3.1525,452,401 - 25,452,648RGD
Celera524,179,453 - 24,179,685UniSTS
RH 3.4 Map5145.2UniSTS
RH 3.4 Map5145.2RGD
SHRSP x BN Map517.09UniSTS
SHRSP x BN Map517.09RGD
Peak: (D5Rat70)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2535,189,153 - 35,189,418 (+)MAPPER
Rnor_6.0535,788,756 - 35,789,020NCBI
Rnor_5.0540,446,731 - 40,446,995UniSTS
RGSC_v3.4536,386,126 - 36,386,391RGD
RGSC_v3.4536,386,127 - 36,386,391UniSTS
RGSC_v3.1536,386,305 - 36,386,570RGD
Celera534,206,778 - 34,207,042UniSTS
RH 3.4 Map5165.4RGD
RH 3.4 Map5165.4UniSTS
RH 2.0 Map5211.5RGD
SHRSP x BN Map520.3999RGD
Cytogenetic Map5q21UniSTS
Flank 2: (D5Rat82)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2544,045,034 - 44,045,280 (+)MAPPER
Rnor_6.0544,746,826 - 44,747,071NCBI
Rnor_5.0549,366,012 - 49,366,257UniSTS
RGSC_v3.4545,822,600 - 45,822,846RGD
RGSC_v3.4545,822,601 - 45,822,846UniSTS
RGSC_v3.1545,822,780 - 45,823,025RGD
Celera542,849,338 - 42,849,596UniSTS
RH 3.4 Map5226.4UniSTS
RH 3.4 Map5226.4RGD
RH 2.0 Map5263.1RGD
SHRSP x BN Map526.0399RGD
FHH x ACI Map527.03RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5213896532656739Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5384401826141981Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
61462Niddm10Non-insulin dependent diabetes mellitus QTL 103.90.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)5511215947171491Rat
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)52483871044045280Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 18 DA/Ztm, 18 PVG/OlaHsd, 24 F1 and 186 F2 1358788
qtl_general measurement method: all animals were anesthetized by isoflurane at 6-8 weeks of age and subjected to unilateral avulsion of the left L3-L5 ventral roots, they were killed and spinal cord examined; serial transverse sections of L4 were cut and examined 1358788
qtl_general LOD=2.39 at D5Rat190 in the G10 conhort 2317162
qtl_statistics_details LOD: 3.6 motoneuron cell number 1358788
qtl_statistics_details linkage analysis performed using MAPMAKER/QTL and R/qtl computer software 1358788