Manea (mannosidase, endo-alpha) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Manea (mannosidase, endo-alpha) Rattus norvegicus
Analyze
Symbol: Manea
Name: mannosidase, endo-alpha
RGD ID: 620327
Description: Enables alpha-mannosidase activity. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in anxiety disorder; cocaine dependence; and panic disorder. Orthologous to human MANEA (mannosidase endo-alpha); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: endo-alpha mannosidase; endo-alpha-D-mannosidase; endo-alpha-mannosidase; endomannosidase; Enman; glycoprotein endo-alpha-1,2-mannosidase; rEndo
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8544,992,937 - 45,015,084 (-)NCBIGRCr8
mRatBN7.2540,196,373 - 40,218,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl540,196,396 - 40,218,459 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx542,298,331 - 42,311,130 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0543,897,348 - 43,910,147 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0543,826,581 - 43,839,380 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0540,845,103 - 40,867,025 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl540,844,998 - 40,867,023 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0545,469,290 - 45,491,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4541,577,651 - 41,590,456 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1541,576,728 - 41,590,474 (-)NCBI
Celera539,058,787 - 39,071,389 (-)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Association of variants in MANEA with cocaine-related behaviors. Farrer LA, etal., Arch Gen Psychiatry. 2009 Mar;66(3):267-74. doi: 10.1001/archgenpsychiatry.2008.538.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The α-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder. Jensen KP, etal., Transl Psychiatry. 2014 Jan 28;4(1):e353. doi: 10.1038/tp.2013.122.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Molecular cloning and expression of rat liver endo-alpha-mannosidase, an N-linked oligosaccharide processing enzyme. Spiro MJ, etal., J Biol Chem 1997 Nov 14;272(46):29356-63.
8. Substance dependence low-density whole genome association study in two distinct American populations. Yu Y, etal., Hum Genet. 2008 Jun;123(5):495-506. doi: 10.1007/s00439-008-0501-0. Epub 2008 Apr 26.
Additional References at PubMed
PMID:12477932   PMID:15677381   PMID:16871372   PMID:18425413  


Genomics

Comparative Map Data
Manea
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8544,992,937 - 45,015,084 (-)NCBIGRCr8
mRatBN7.2540,196,373 - 40,218,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl540,196,396 - 40,218,459 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx542,298,331 - 42,311,130 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0543,897,348 - 43,910,147 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0543,826,581 - 43,839,380 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0540,845,103 - 40,867,025 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl540,844,998 - 40,867,023 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0545,469,290 - 45,491,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4541,577,651 - 41,590,456 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1541,576,728 - 41,590,474 (-)NCBI
Celera539,058,787 - 39,071,389 (-)NCBICelera
Cytogenetic Map5q21NCBI
MANEA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38695,577,535 - 95,609,452 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl695,577,485 - 95,609,470 (+)EnsemblGRCh38hg38GRCh38
GRCh37696,025,411 - 96,057,328 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36696,132,134 - 96,164,047 (+)NCBINCBI36Build 36hg18NCBI36
Build 34696,132,133 - 96,164,047NCBI
Celera696,666,751 - 96,698,498 (+)NCBICelera
Cytogenetic Map6q16.1NCBI
HuRef693,458,650 - 93,490,603 (+)NCBIHuRef
CHM1_1696,287,324 - 96,319,327 (+)NCBICHM1_1
T2T-CHM13v2.0696,748,485 - 96,780,392 (+)NCBIT2T-CHM13v2.0
Manea
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39426,324,506 - 26,346,913 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl426,324,506 - 26,346,891 (-)EnsemblGRCm39 Ensembl
GRCm38426,324,506 - 26,346,918 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl426,324,506 - 26,346,891 (-)EnsemblGRCm38mm10GRCm38
MGSCv37426,251,653 - 26,273,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36426,415,136 - 26,437,282 (-)NCBIMGSCv36mm8
Celera426,032,320 - 26,054,498 (-)NCBICelera
Cytogenetic Map4A3NCBI
cM Map410.92NCBI
Manea
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541121,735,550 - 21,761,750 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541121,729,085 - 21,763,684 (+)NCBIChiLan1.0ChiLan1.0
MANEA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25115,627,414 - 115,666,203 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16113,512,496 - 113,544,251 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0693,428,813 - 93,460,576 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1697,316,022 - 97,347,768 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl697,316,022 - 97,347,768 (+)Ensemblpanpan1.1panPan2
MANEA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11254,156,398 - 54,229,183 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1254,170,184 - 54,225,013 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1253,963,772 - 54,036,664 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01254,972,172 - 55,045,434 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1254,982,280 - 55,042,970 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11254,294,305 - 54,367,550 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01254,169,174 - 54,241,745 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01254,371,139 - 54,444,695 (+)NCBIUU_Cfam_GSD_1.0
Manea
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494688,721,181 - 88,752,631 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366991,975,362 - 2,006,932 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366991,975,391 - 2,006,816 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MANEA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl162,887,881 - 62,945,583 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1162,887,689 - 62,945,586 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2171,027,088 - 71,084,858 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MANEA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11320,496,677 - 20,529,201 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1320,496,686 - 20,530,819 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040196,752,522 - 196,783,748 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Manea
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248109,961,154 - 9,998,835 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Manea
52 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:644
Count of miRNA genes:286
Interacting mature miRNAs:368
Transcripts:ENSRNOT00000011576
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
61462Niddm10Non-insulin dependent diabetes mellitus QTL 103.90.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)5511215947171491Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)52483871044045280Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat

Markers in Region
RH135326  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2540,197,099 - 40,197,304 (+)MAPPERmRatBN7.2
Rnor_6.0540,845,590 - 40,845,794NCBIRnor6.0
Rnor_5.0545,469,777 - 45,469,981UniSTSRnor5.0
RGSC_v3.4541,575,412 - 41,575,616UniSTSRGSC3.4
Celera539,056,548 - 39,056,752UniSTS
RH 3.4 Map5216.9UniSTS
Cytogenetic Map5q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 18 48 69 61 12 61 229 88 104 41
Low 3 93 158 86 57 86 36 42 27 41 24
Below cutoff

Sequence


Ensembl Acc Id: ENSRNOT00000011576   ⟹   ENSRNOP00000011576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl540,196,396 - 40,218,459 (-)Ensembl
Rnor_6.0 Ensembl540,844,998 - 40,867,023 (-)Ensembl
RefSeq Acc Id: NM_080785   ⟹   NP_542963
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8544,992,937 - 45,015,084 (-)NCBI
mRatBN7.2540,196,393 - 40,218,540 (-)NCBI
Rnor_6.0540,847,829 - 40,860,634 (-)NCBI
Rnor_5.0545,469,290 - 45,491,210 (-)NCBI
RGSC_v3.4541,577,651 - 41,590,456 (-)RGD
Celera539,058,787 - 39,071,389 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237961   ⟹   XP_006238023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8544,992,937 - 45,015,075 (-)NCBI
mRatBN7.2540,196,373 - 40,218,251 (-)NCBI
Rnor_6.0540,845,103 - 40,866,751 (-)NCBI
Rnor_5.0545,469,290 - 45,491,210 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_542963 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238023 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAT44962 (Get FASTA)   NCBI Sequence Viewer  
  EDL98547 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011576.4
  ENSRNOP00055013847
  ENSRNOP00060018805
  ENSRNOP00065006006
GenBank Protein Q5GF25 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_542963   ⟸   NM_080785
- UniProtKB: O35390 (UniProtKB/Swiss-Prot),   Q5GF25 (UniProtKB/Swiss-Prot),   A6IIH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238023   ⟸   XM_006237961
- Peptide Label: isoform X1
- UniProtKB: O35390 (UniProtKB/Swiss-Prot),   Q5GF25 (UniProtKB/Swiss-Prot),   A6IIH7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011576   ⟸   ENSRNOT00000011576

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5GF25-F1-model_v2 AlphaFold Q5GF25 1-462 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693607
Promoter ID:EPDNEW_R4132
Type:initiation region
Name:Manea_1
Description:mannosidase, endo-alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0540,866,965 - 40,867,025EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620327 AgrOrtholog
BioCyc Gene G2FUF-41773 BioCyc
BioCyc Pathway PWY-7919 [protein N-glycosylation processing phase (plants and animals)] BioCyc
BioCyc Pathway Image PWY-7919 BioCyc
Ensembl Genes ENSRNOG00000008626 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055010191 UniProtKB/Swiss-Prot
  ENSRNOG00060013846 UniProtKB/Swiss-Prot
  ENSRNOG00065005709 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011576.7 UniProtKB/Swiss-Prot
  ENSRNOT00055017207 UniProtKB/Swiss-Prot
  ENSRNOT00060023653 UniProtKB/Swiss-Prot
  ENSRNOT00065008521 UniProtKB/Swiss-Prot
Gene3D-CATH Glycosidases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glyco_Hydrolase_99 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:140808 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 140808 ENTREZGENE
PANTHER ENDO-ALPHA-1,2-MANNOSIDASE UniProtKB/TrEMBL
  GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13572 UniProtKB/Swiss-Prot
Pfam Glyco_hydro_99 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Manea PhenoGen
RatGTEx ENSRNOG00000008626 RatGTEx
  ENSRNOG00055010191 RatGTEx
  ENSRNOG00060013846 RatGTEx
  ENSRNOG00065005709 RatGTEx
UniProt A6IIH7 ENTREZGENE, UniProtKB/TrEMBL
  MANEA_RAT UniProtKB/Swiss-Prot
  O35390 ENTREZGENE
  Q5GF25 ENTREZGENE
UniProt Secondary O35390 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Manea  mannosidase, endo-alpha  Enman  endo-alpha-mannosidase  Symbol and Name updated 1299863 APPROVED
2002-08-07 Enman  endo-alpha-mannosidase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in all tissues 632807
gene_protein 451 amino acids; 52 kDa 632807