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Gene: Bach2 (BTB domain and CNC homolog 2) Rattus norvegicus
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Symbol: Bach2
Name: BTB domain and CNC homolog 2
RGD ID: 1562865
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in import into nucleus; negative regulation of transcription by RNA polymerase II; and primary adaptive immune response involving T cells and B cells. Predicted to localize to cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 60. Orthologous to human BACH2 (BTB domain and CNC homolog 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BTB and CNC homology 1, basic leucine zipper transcription factor 2; BTB and CNC homology 2; LOC313125; RGD1562865; similar to BTB and CNC homology 1, basic leucine zipper transcription factor 2; transcription regulator protein BACH2
Orthologs:
Homo sapiens (human) : BACH2 (BTB domain and CNC homolog 2)  HGNC  Alliance
Mus musculus (house mouse) : Bach2 (BTB and CNC homology, basic leucine zipper transcription factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bach2 (BTB domain and CNC homolog 2)
Pan paniscus (bonobo/pygmy chimpanzee) : BACH2 (BTB domain and CNC homolog 2)
Canis lupus familiaris (dog) : BACH2 (BTB domain and CNC homolog 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bach2 (BTB domain and CNC homolog 2)
Sus scrofa (pig) : BACH2 (BTB domain and CNC homolog 2)
Chlorocebus sabaeus (African green monkey) : BACH2 (BTB domain and CNC homolog 2)
Heterocephalus glaber (naked mole-rat) : Bach2 (BTB domain and CNC homolog 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0547,458,891 - 47,807,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl547,546,014 - 47,807,166 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0552,073,295 - 52,410,910 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4548,611,805 - 48,881,943 (+)NCBIRGSC3.4rn4RGSC3.4
Celera545,479,904 - 45,738,863 (+)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Bach2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562865
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.