Ccnc (cyclin C) - Rat Genome Database

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Gene: Ccnc (cyclin C) Rattus norvegicus
Analyze
Symbol: Ccnc
Name: cyclin C
RGD ID: 70905
Description: Contributes to ubiquitin protein ligase activity. Involved in negative regulation of triglyceride metabolic process and protein ubiquitination. Part of ubiquitin ligase complex. Orthologous to human CCNC (cyclin C); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cyclin-C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,063,589 - 40,081,731 (+)NCBIGRCr8
mRatBN7.2535,266,828 - 35,284,943 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl535,266,823 - 35,296,584 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx537,391,253 - 37,409,196 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0538,983,996 - 39,001,939 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0538,923,510 - 38,941,449 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0535,865,598 - 35,883,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl535,865,605 - 35,883,706 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0540,521,947 - 40,540,039 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4536,465,490 - 36,483,538 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1536,465,668 - 36,482,416 (+)NCBI
Celera534,283,507 - 34,301,554 (+)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Burns  (IEP)
genetic disease  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-amphetamine  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrotoluene  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphibole asbestos  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
carbon nanotube  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
chlorpyrifos  (ISO)
cobalt atom  (ISO)
dexamethasone  (ISO)
diallyl disulfide  (EXP)
dibutyl phthalate  (ISO)
dichlorine  (EXP)
dicrotophos  (ISO)
dihydroxyacetone  (ISO)
dimethylarsinic acid  (ISO)
disodium selenite  (ISO)
elemental selenium  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
kojic acid  (ISO)
L-ascorbic acid  (ISO)
lamivudine  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (ISO)
metformin  (ISO)
methylmercury chloride  (ISO)
Monobutylphthalate  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
nickel dichloride  (EXP)
ozone  (EXP)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenytoin  (EXP)
piperonyl butoxide  (ISO)
piroxicam  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
tremolite asbestos  (ISO)
usnic acid  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. Brower CS, etal., Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10353-8. Epub 2002 Jul 29.
2. Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3). Demetrick DJ, etal., Cytogenet Cell Genet 1995;69(3-4):190-2.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Molecular cloning and chromosomal localization of the human cyclin C (CCNC) and cyclin E (CCNE) genes: deletion of the CCNC gene in human tumors. Li H, etal., Genomics 1996 Mar 1;32(2):253-9.
6. Gene Data Set MGD Curation, June 12, 2002
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. The Mediator complex and transcription regulation. Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Cyclin G: a new mammalian cyclin with homology to fission yeast Cig1. Tamura K, etal., Oncogene 1993 Aug;8(8):2113-8.
14. [Influence of aerosols on the expression of cyclin B1, cyclin C and proliferating cell nuclear antigen in wound tissue healing of burned rat models] Zhang T, etal., Zhonghua Wai Ke Za Zhi. 2005 Oct 1;43(19):1280-3.
15. Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. Zhao X, etal., J Clin Invest. 2012 Jul 2;122(7):2417-27. doi: 10.1172/JCI61462. Epub 2012 Jun 11.
Additional References at PubMed
PMID:12477932   PMID:15340084   PMID:19103257  


Genomics

Comparative Map Data
Ccnc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8540,063,589 - 40,081,731 (+)NCBIGRCr8
mRatBN7.2535,266,828 - 35,284,943 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl535,266,823 - 35,296,584 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx537,391,253 - 37,409,196 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0538,983,996 - 39,001,939 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0538,923,510 - 38,941,449 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0535,865,598 - 35,883,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl535,865,605 - 35,883,706 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0540,521,947 - 40,540,039 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4536,465,490 - 36,483,538 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1536,465,668 - 36,482,416 (+)NCBI
Celera534,283,507 - 34,301,554 (+)NCBICelera
Cytogenetic Map5q21NCBI
CCNC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38699,542,387 - 99,568,814 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl699,542,387 - 99,568,825 (-)EnsemblGRCh38hg38GRCh38
GRCh37699,990,263 - 100,016,690 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366100,096,984 - 100,123,411 (-)NCBINCBI36Build 36hg18NCBI36
Build 346100,097,585 - 100,123,213NCBI
Celera6100,634,399 - 100,660,812 (-)NCBICelera
Cytogenetic Map6q16.2NCBI
HuRef697,430,596 - 97,457,015 (-)NCBIHuRef
CHM1_16100,253,182 - 100,279,594 (-)NCBICHM1_1
T2T-CHM13v2.06100,716,675 - 100,743,083 (-)NCBIT2T-CHM13v2.0
Ccnc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39421,727,705 - 21,759,917 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl421,727,701 - 21,759,922 (+)EnsemblGRCm39 Ensembl
GRCm38421,727,701 - 21,759,922 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl421,727,701 - 21,759,922 (+)EnsemblGRCm38mm10GRCm38
MGSCv37421,654,850 - 21,677,693 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36421,818,565 - 21,841,381 (+)NCBIMGSCv36mm8
Celera421,472,732 - 21,495,573 (+)NCBICelera
Cytogenetic Map4A3NCBI
cM Map48.86NCBI
Ccnc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541125,415,023 - 25,447,874 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541125,415,023 - 25,447,874 (-)NCBIChiLan1.0ChiLan1.0
CCNC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25119,588,885 - 119,615,194 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16117,470,054 - 117,496,887 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0697,383,290 - 97,410,068 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16101,265,499 - 101,292,233 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6101,265,499 - 101,292,233 (-)Ensemblpanpan1.1panPan2
CCNC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11257,738,576 - 57,760,918 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1257,739,616 - 57,759,609 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1257,495,633 - 57,522,278 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01258,560,188 - 58,586,841 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1258,560,188 - 58,586,767 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11257,916,655 - 57,943,256 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01257,763,569 - 57,790,252 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01258,009,273 - 58,035,972 (-)NCBIUU_Cfam_GSD_1.0
Ccnc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494692,668,123 - 92,703,700 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366511,140,895 - 1,163,944 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366511,123,546 - 1,159,089 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCNC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl166,471,782 - 66,499,188 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1166,472,622 - 66,499,754 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2175,149,770 - 75,175,355 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCNC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11374,312,485 - 74,338,843 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1374,312,228 - 74,339,369 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604046,644,816 - 46,671,444 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccnc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248105,466,981 - 5,485,930 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248105,466,972 - 5,485,932 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ccnc
93 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:95
Interacting mature miRNAs:101
Transcripts:ENSRNOT00000011442
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
61462Niddm10Non-insulin dependent diabetes mellitus QTL 103.90.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)5511215947171491Rat
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)52483871044045280Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat

Markers in Region
RH129921  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2535,284,590 - 35,284,807 (+)MAPPERmRatBN7.2
Rnor_6.0535,883,380 - 35,883,596NCBIRnor6.0
Rnor_5.0540,539,687 - 40,539,903UniSTSRnor5.0
RGSC_v3.4536,483,186 - 36,483,402UniSTSRGSC3.4
Celera534,301,202 - 34,301,418UniSTS
RH 3.4 Map5199.81UniSTS
Cytogenetic Map5q21UniSTS
RH129977  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2535,284,640 - 35,284,821 (+)MAPPERmRatBN7.2
Rnor_6.0535,883,430 - 35,883,610NCBIRnor6.0
Rnor_5.0540,539,737 - 40,539,917UniSTSRnor5.0
RGSC_v3.4536,483,236 - 36,483,416UniSTSRGSC3.4
Celera534,301,252 - 34,301,432UniSTS
RH 3.4 Map5166.6UniSTS
Cytogenetic Map5q21UniSTS
BI284677  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2535,281,898 - 35,282,114 (+)MAPPERmRatBN7.2
Rnor_6.0535,880,688 - 35,880,903NCBIRnor6.0
Rnor_5.0540,536,995 - 40,537,210UniSTSRnor5.0
RGSC_v3.4536,480,494 - 36,480,709UniSTSRGSC3.4
Celera534,298,510 - 34,298,725UniSTS
RH 3.4 Map9813.9UniSTS
Cytogenetic Map5q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 28 53 37 18 37 1 1 74 34 39 11 1
Low 15 4 4 1 4 7 10 1 2 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000011442   ⟹   ENSRNOP00000011442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl535,266,860 - 35,284,941 (+)Ensembl
Rnor_6.0 Ensembl535,865,605 - 35,883,706 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107276   ⟹   ENSRNOP00000095999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl535,266,823 - 35,296,584 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110130   ⟹   ENSRNOP00000086557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl535,266,893 - 35,282,372 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112239   ⟹   ENSRNOP00000079034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl535,268,807 - 35,282,007 (+)Ensembl
RefSeq Acc Id: NM_001100472   ⟹   NP_001093942
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,063,683 - 40,081,731 (+)NCBI
mRatBN7.2535,266,893 - 35,284,943 (+)NCBI
Rnor_6.0535,865,684 - 35,883,732 (+)NCBI
Rnor_5.0540,521,947 - 40,540,039 (+)NCBI
RGSC_v3.4536,465,490 - 36,483,538 (+)RGD
Celera534,283,507 - 34,301,554 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237937   ⟹   XP_006237999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,063,589 - 40,081,731 (+)NCBI
mRatBN7.2535,266,846 - 35,282,375 (+)NCBI
Rnor_6.0535,865,598 - 35,881,164 (+)NCBI
Rnor_5.0540,521,947 - 40,540,039 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109128   ⟹   XP_038965056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,063,589 - 40,081,731 (+)NCBI
mRatBN7.2535,266,845 - 35,284,943 (+)NCBI
RefSeq Acc Id: XM_063287061   ⟹   XP_063143131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,063,589 - 40,079,163 (+)NCBI
RefSeq Acc Id: XM_063287062   ⟹   XP_063143132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8540,067,426 - 40,079,163 (+)NCBI
RefSeq Acc Id: NP_001093942   ⟸   NM_001100472
- UniProtKB: P39947 (UniProtKB/Swiss-Prot),   G3V738 (UniProtKB/TrEMBL),   A6IIE2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237999   ⟸   XM_006237937
- Peptide Label: isoform X2
- UniProtKB: P39947 (UniProtKB/Swiss-Prot),   A0A8I6A408 (UniProtKB/TrEMBL),   A6IIE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000011442   ⟸   ENSRNOT00000011442
RefSeq Acc Id: XP_038965056   ⟸   XM_039109128
- Peptide Label: isoform X2
- UniProtKB: P39947 (UniProtKB/Swiss-Prot),   A0A8I6A408 (UniProtKB/TrEMBL),   A6IIE3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000079034   ⟸   ENSRNOT00000112239
RefSeq Acc Id: ENSRNOP00000086557   ⟸   ENSRNOT00000110130
RefSeq Acc Id: ENSRNOP00000095999   ⟸   ENSRNOT00000107276
RefSeq Acc Id: XP_063143131   ⟸   XM_063287061
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063143132   ⟸   XM_063287062
- Peptide Label: isoform X3
Protein Domains
Cyclin N-terminal   Cyclin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P39947-F1-model_v2 AlphaFold P39947 1-278 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693594
Promoter ID:EPDNEW_R4119
Type:multiple initiation site
Name:Ccnc_1
Description:cyclin C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0535,865,684 - 35,865,744EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70905 AgrOrtholog
BioCyc Gene G2FUF-41816 BioCyc
Ensembl Genes ENSRNOG00000007719 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011442 ENTREZGENE
  ENSRNOT00000011442.7 UniProtKB/TrEMBL
  ENSRNOT00000107276.1 UniProtKB/TrEMBL
  ENSRNOT00000110130.1 UniProtKB/TrEMBL
  ENSRNOT00000112239.1 UniProtKB/TrEMBL
Gene3D-CATH Cyclin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyclin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin/Ssn8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_C_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:114839 UniProtKB/TrEMBL
NCBI Gene 114839 ENTREZGENE
PANTHER PTHR10026 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10026:SF7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cyclin_C_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccnc PhenoGen
PIRSF Cyclin, C/H/G types UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007719 RatGTEx
SMART CYCLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47954 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZM04_RAT UniProtKB/TrEMBL
  A0A8I6A408 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AP22_RAT UniProtKB/TrEMBL
  A6IIE2 ENTREZGENE, UniProtKB/TrEMBL
  A6IIE3 ENTREZGENE, UniProtKB/TrEMBL
  A6IIE4_RAT UniProtKB/TrEMBL
  A6IIE5_RAT UniProtKB/TrEMBL
  CCNC_RAT UniProtKB/Swiss-Prot
  G3V738 ENTREZGENE, UniProtKB/TrEMBL
  P39947 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Ccnc  cyclin C      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease human homolog is deleted in a subset of acute lymphoblastic leukemias 728375