Gene: Fbxl4 (F-box and leucine-rich repeat protein 4) Rattus norvegicus
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Symbol: Fbxl4
Name: F-box and leucine-rich repeat protein 4
Description: INVOLVED IN protein ubiquitination (inferred); ASSOCIATED WITH Developmental Disabilities (ortholog); genetic disease (ortholog); mitochondrial DNA depletion syndrome 13 (ortholog); FOUND IN mitochondrial intermembrane space (ortholog); nuclear speck (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; finasteride
AGR Description: Predicted to contribute to ubiquitin-protein transferase activity; predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; predicted to localize to the SCF ubiquitin ligase complex, mitochondrial intermembrane space, and nuclear speck; orthologous to human FBXL4 (F-box and leucine rich repeat protein 4).
Merged Description: Predicted to contribute to ubiquitin-protein transferase activity; predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; predicted to localize to the SCF ubiquitin ligase complex, mitochondrial intermembrane space, and nuclear speck; orthologous to human FBXL4 (F-box and leucine rich repeat protein 4); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; finasteride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: F-box/LRR-repeat protein 4; LOC313101
Orthologs:
Homo sapiens (human) : FBXL4 (F-box and leucine rich repeat protein 4)  HGNC  Alliance
Mus musculus (house mouse) : Fbxl4 (F-box and leucine-rich repeat protein 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxl4 (F-box and leucine rich repeat protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXL4 (F-box and leucine rich repeat protein 4)
Canis lupus familiaris (dog) : FBXL4 (F-box and leucine rich repeat protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxl4 (F-box and leucine rich repeat protein 4)
Sus scrofa (pig) : FBXL4 (F-box and leucine rich repeat protein 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0536,555,061 - 36,628,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0541,196,912 - 41,270,903 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4537,156,876 - 37,230,228 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1537,157,055 - 37,230,404 (+)NCBI
Celera534,966,228 - 35,039,999 (+)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fbxl4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305724
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.