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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SLCO5A1 mRNA | CTD | PMID:29097150 | 17beta-estradiol | increases expression | ISO | RGD:1316144 | 6480464 | Estradiol results in increased expression of SLCO5A1 mRNA | CTD | PMID:31614463 | 3-Iodothyronamine | affects uptake | ISO | RGD:1316144 | 6480464 | SLCO5A1 mRNA affects the uptake of 3-iodothyronamine | CTD | PMID:19074582 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RGD:1316144 | 6480464 | [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of SLCO5A1 gene | CTD | PMID:31601247 | 4,4'-sulfonyldiphenol | affects methylation | ISO | RGD:1316145 | 6480464 | bis(4-hydroxyphenyl)sulfone affects the methylation of SLCO5A1 gene | CTD | PMID:31683443 | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of SLCO5A1 mRNA | CTD | PMID:24780913 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SLCO5A1 mRNA | CTD | PMID:25825206, PMID:30047161 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SLCO5A1 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of SLCO5A1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | RGD:1316144 | 6480464 | Aflatoxin B1 results in decreased methylation of SLCO5A1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | RGD:1316144 | 6480464 | Tretinoin results in increased expression of SLCO5A1 mRNA | CTD | PMID:33167477 | amiodarone | increases expression | ISO | RGD:1316144 | 6480464 | Amiodarone results in increased expression of SLCO5A1 mRNA | CTD | PMID:19774075 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of SLCO5A1 mRNA | CTD | PMID:30047161 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of SLCO5A1 mRNA | CTD | PMID:30779732 | benzo[a]pyrene | decreases methylation | ISO | RGD:1316144 | 6480464 | Benzo(a)pyrene results in decreased methylation of SLCO5A1 exon | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | RGD:1316144 | 6480464 | Benzo(a)pyrene affects the methylation of SLCO5A1 3' UTR more ... | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | RGD:1316144 | 6480464 | benzo(e)pyrene results in increased methylation of SLCO5A1 intron | CTD | PMID:30157460 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLCO5A1 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SLCO5A1 mRNA | CTD | PMID:30816183 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SLCO5A1 gene | CTD | PMID:28505145 | CGP 52608 | multiple interactions | ISO | RGD:1316144 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SLCO5A1 gene] | CTD | PMID:28238834 | crocidolite asbestos | decreases expression | ISO | RGD:1316145 | 6480464 | Asbestos, Crocidolite results in decreased expression of SLCO5A1 mRNA | CTD | PMID:23917077 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of SLCO5A1 mRNA | CTD | PMID:26577399 | dimethylarsinic acid | multiple interactions | ISO | RGD:1316145 | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SLCO5A1 mRNA | CTD | PMID:34876320 | ethyl methanesulfonate | decreases expression | ISO | RGD:1316144 | 6480464 | Ethyl Methanesulfonate results in decreased expression of SLCO5A1 mRNA | CTD | PMID:23649840 | fulvestrant | multiple interactions | ISO | RGD:1316144 | 6480464 | [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of SLCO5A1 gene | CTD | PMID:31601247 | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of SLCO5A1 mRNA | CTD | PMID:25539665 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SLCO5A1 mRNA | CTD | PMID:33387578 | hydroquinone O-beta-D-glucopyranoside | decreases expression | ISO | RGD:1316144 | 6480464 | Arbutin results in decreased expression of SLCO5A1 mRNA | CTD | PMID:17103032 | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of SLCO5A1 mRNA | CTD | PMID:20080153 | lipopolysaccharide | increases expression | ISO | RGD:1316144 | 6480464 | Lipopolysaccharides results in increased expression of SLCO5A1 mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | ISO | RGD:1316144 | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | methapyrilene | increases methylation | ISO | RGD:1316144 | 6480464 | Methapyrilene results in increased methylation of SLCO5A1 intron | CTD | PMID:30157460 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of SLCO5A1 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | decreases expression | ISO | RGD:1316144 | 6480464 | Methyl Methanesulfonate results in decreased expression of SLCO5A1 mRNA | CTD | PMID:23649840 | methylarsonic acid | multiple interactions | ISO | RGD:1316145 | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SLCO5A1 mRNA | CTD | PMID:34876320 | methylmercury chloride | increases expression | ISO | RGD:1316144 | 6480464 | methylmercuric chloride results in increased expression of SLCO5A1 mRNA | CTD | PMID:28001369 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of SLCO5A1 gene | CTD | PMID:33148267 | nickel atom | increases expression | ISO | RGD:1316144 | 6480464 | Nickel results in increased expression of SLCO5A1 mRNA | CTD | PMID:24768652, PMID:25583101 | niclosamide | increases expression | ISO | RGD:1316144 | 6480464 | Niclosamide results in increased expression of SLCO5A1 mRNA | CTD | PMID:36318118 | ozone | multiple interactions | ISO | RGD:1316145 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of SLCO5A1 mRNA | CTD | PMID:34911549 | paracetamol | increases expression | ISO | RGD:1316144 | 6480464 | Acetaminophen results in increased expression of SLCO5A1 mRNA | CTD | PMID:29067470 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SLCO5A1 mRNA | CTD | PMID:33387578 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of SLCO5A1 gene | CTD | PMID:33148267 | pioglitazone | multiple interactions | ISO | RGD:1316145 | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLCO5A1 mRNA | CTD | PMID:27935865 | progesterone | multiple interactions | ISO | RGD:1316145 | 6480464 | NCOA2 protein affects the reaction [Progesterone results in increased expression of SLCO5A1 mRNA] | CTD | PMID:17556502 | progesterone | increases expression | ISO | RGD:1316145 | 6480464 | Progesterone results in increased expression of SLCO5A1 mRNA | CTD | PMID:17556502 | quercetin | increases uptake | ISO | RGD:1316144 | 6480464 | SLCO5A1 protein results in increased uptake of Quercetin | CTD | PMID:24947867 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | RGD:1316144 | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | silicon dioxide | increases expression | ISO | RGD:1316144 | 6480464 | Silicon Dioxide results in increased expression of SLCO5A1 mRNA | CTD | PMID:25351596 | silver atom | decreases expression | ISO | RGD:1316145 | 6480464 | Silver results in decreased expression of SLCO5A1 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | RGD:1316145 | 6480464 | Silver results in decreased expression of SLCO5A1 mRNA | CTD | PMID:27131904 | sodium arsenate | increases expression | ISO | RGD:1316145 | 6480464 | sodium arsenate results in increased expression of SLCO5A1 mRNA | CTD | PMID:30953684 | sodium arsenate | multiple interactions | ISO | RGD:1316145 | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SLCO5A1 mRNA | CTD | PMID:34876320 | sodium arsenite | decreases expression | ISO | RGD:1316144 | 6480464 | sodium arsenite results in decreased expression of SLCO5A1 mRNA | CTD | PMID:25879800 | sodium arsenite | multiple interactions | ISO | RGD:1316145 | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SLCO5A1 mRNA | CTD | PMID:34876320 | sunitinib | decreases expression | ISO | RGD:1316144 | 6480464 | Sunitinib results in decreased expression of SLCO5A1 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | ISO | RGD:1316144 | 6480464 | Temozolomide results in increased expression of SLCO5A1 mRNA | CTD | PMID:31758290 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SLCO5A1 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | RGD:1316145 | 6480464 | titanium dioxide results in decreased expression of SLCO5A1 mRNA | CTD | PMID:29264374 | xylitol | increases expression | ISO | RGD:1316144 | 6480464 | Xylitol results in increased expression of SLCO5A1 mRNA | CTD | PMID:32275922 | |