(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NCOA2 mRNA] CTD PMID:31150632 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:732737 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NCOA2 mRNA CTD PMID:22079256 (R)-linalyl acetate multiple interactions ISO RGD:732737 6480464 NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 (S)-colchicine multiple interactions ISO RGD:732737 6480464 Colchicine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NR1H4 protein affects the localization of NCOA2 protein]] CTD PMID:25257666 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO RGD:732738 6480464 NCOA2 protein promotes the reaction [2 more ... CTD PMID:27634370 17beta-estradiol multiple interactions ISO RGD:732737 6480464 9 more ... CTD PMID:10964929 more ... 17beta-estradiol multiple interactions ISO RGD:732738 6480464 NCOA2 protein inhibits the reaction [ESR2 protein alternative form inhibits the reaction [Estradiol results in increased expression of ESR2 protein]] more ... CTD PMID:27634370 17beta-estradiol affects localization ISO RGD:732738 6480464 Estradiol affects the localization of NCOA2 protein CTD PMID:17556502 17beta-estradiol increases expression ISO RGD:732737 6480464 Estradiol results in increased expression of NCOA2 protein CTD PMID:16739346 17beta-estradiol affects binding ISO RGD:732737 6480464 [Estradiol binds to ESR1 protein] which binds to NCOA2 protein, [Estradiol binds to ESR2 protein] which binds to NCOA2 protein CTD PMID:15123288 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:732737 6480464 [Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA2 protein modified form] more ... CTD PMID:19131511 , PMID:28751236 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO RGD:732737 6480464 Dihydrotestosterone promotes the reaction [NCOA2 protein binds to KLK3 promoter] more ... CTD PMID:15336702 more ... 2,3,4,5-Tetrachloro-4'-biphenylol multiple interactions ISO RGD:732737 6480464 2' more ... CTD PMID:10964929 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732737 6480464 NCOA2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] more ... CTD PMID:12024042 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732738 6480464 Tetrachlorodibenzodioxin affects the expression of NCOA2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:732737 6480464 Tetrachlorodibenzodioxin results in increased expression of NCOA2 mRNA CTD PMID:12377990 , PMID:15345368 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol multiple interactions EXP 6480464 clofoctol promotes the reaction [THRA protein binds to NCOA2 protein], clofoctol promotes the reaction [THRB protein binds to NCOA2 protein] CTD PMID:31566444 2-hydroxypropanoic acid decreases expression ISO RGD:732737 6480464 Lactic Acid results in decreased expression of NCOA2 mRNA CTD PMID:30851411 22,23-dihydroavermectin B1a multiple interactions ISO RGD:732737 6480464 22, 23-dihydroavermectin B(1)a inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NR1H4 protein affects the localization of NCOA2 protein]] CTD PMID:25257666 3,3',5'-triiodo-L-thyronine multiple interactions ISO RGD:732737 6480464 Triiodothyronine, Reverse promotes the reaction [THRA protein binds to NCOA2 protein], Triiodothyronine, Reverse promotes the reaction [THRB protein binds to NCOA2 protein] CTD PMID:31566444 3,3',5'-triiodothyronine multiple interactions ISO RGD:732737 6480464 Triiodothyronine, Reverse promotes the reaction [THRA protein binds to NCOA2 protein], Triiodothyronine, Reverse promotes the reaction [THRB protein binds to NCOA2 protein] CTD PMID:31566444 3,3',5,5'-tetraiodothyroacetic acid multiple interactions ISO RGD:732737 6480464 tetraiodothyroacetic acid promotes the reaction [THRA protein binds to NCOA2 protein], tetraiodothyroacetic acid promotes the reaction [THRB protein binds to NCOA2 protein] CTD PMID:31566444 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:732737 6480464 Triiodothyronine promotes the reaction [NCOA2 protein binds to THRA protein] more ... CTD PMID:29146198 , PMID:31566444 3,3'-diindolylmethane multiple interactions ISO RGD:732737 6480464 3 more ... CTD PMID:20160136 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol multiple interactions ISO RGD:732737 6480464 1H more ... CTD PMID:17603182 3,4-methylenedioxymethamphetamine increases expression ISO RGD:732738 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of NCOA2 mRNA CTD PMID:20188158 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:732738 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of NCOA2 mRNA CTD PMID:26251327 3beta-hydroxycholest-5-en-26-oic acid multiple interactions ISO RGD:732737 6480464 3-hydroxy-5-cholestenoic acid affects the reaction [NR1H3 protein binds to NCOA2 protein] CTD PMID:11089551 4'-epidoxorubicin multiple interactions ISO RGD:732737 6480464 Epirubicin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NR1H4 protein affects the localization of NCOA2 protein]] CTD PMID:25257666 4,4'-sulfonyldiphenol multiple interactions ISO RGD:732737 6480464 bis(4-hydroxyphenyl)sulfone promotes the reaction [ESR1 protein binds to NCOA2 protein], bis(4-hydroxyphenyl)sulfone promotes the reaction [NCOA2 protein binds to THRB protein] CTD PMID:29146198 , PMID:29389661 4-terpineol multiple interactions ISO RGD:732737 6480464 NCOA2 protein promotes the reaction [terpinenol-4 results in increased activity of ESR1 protein] CTD PMID:31393563 4-tert-Octylphenol multiple interactions ISO RGD:732737 6480464 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA2 protein], 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA2 protein] CTD PMID:10964929 9,9-bis(4-hydroxyphenyl)fluorene multiple interactions ISO RGD:732737 6480464 9, 9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [[Estradiol co-treated with ESR1 protein] results in increased activity of NCOA2 protein] CTD PMID:28248286 [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID multiple interactions ISO RGD:732737 6480464 3 more ... CTD PMID:31566444 afimoxifene multiple interactions ISO RGD:732737 6480464 afimoxifene inhibits the reaction [[Estradiol co-treated with ESR1 protein] results in increased activity of NCOA2 protein] more ... CTD PMID:23583298 , PMID:28248286 aflatoxin B1 affects expression ISO RGD:732737 6480464 Aflatoxin B1 affects the expression of NCOA2 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO RGD:732737 6480464 Aflatoxin B1 results in decreased methylation of NCOA2 3' UTR, Aflatoxin B1 results in decreased methylation of NCOA2 gene CTD PMID:27153756 , PMID:30157460 all-trans-acitretin multiple interactions ISO RGD:732737 6480464 Acitretin promotes the reaction [THRB protein binds to NCOA2 protein] CTD PMID:31566444 all-trans-retinoic acid multiple interactions ISO RGD:732738 6480464 Tretinoin affects the reaction [NCOA2 protein binds to NR2C1 promoter] CTD PMID:17389641 all-trans-retinoic acid multiple interactions ISO RGD:732737 6480464 Tretinoin promotes the reaction [RARA protein binds to NCOA2 protein] CTD PMID:15578590 alpha-terpineol multiple interactions ISO RGD:732737 6480464 NCOA2 protein promotes the reaction [alpha-terpineol results in increased activity of ESR1 protein] CTD PMID:31393563 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of NCOA2 mRNA CTD PMID:16483693 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of NCOA2 mRNA CTD PMID:30779732 androst-4-ene-3,17-dione multiple interactions ISO RGD:732737 6480464 NCOA2 protein promotes the reaction [Androstenedione binds to and results in increased activity of AR protein] CTD PMID:15336702 arsenous acid multiple interactions ISO RGD:732737 6480464 Arsenic Trioxide inhibits the reaction [Metribolone promotes the reaction [NCOA2 protein binds to KLK3 promoter]] CTD PMID:19131511 atrazine decreases expression ISO RGD:732738 6480464 Atrazine results in decreased expression of NCOA2 mRNA CTD PMID:26518232 benidipine multiple interactions ISO RGD:732737 6480464 benidipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 benzo[a]pyrene decreases expression ISO RGD:732738 6480464 Benzo(a)pyrene results in decreased expression of NCOA2 mRNA CTD PMID:19770486 benzo[a]pyrene affects methylation ISO RGD:732737 6480464 Benzo(a)pyrene affects the methylation of NCOA2 intron CTD PMID:30157460 benzo[a]pyrene multiple interactions ISO RGD:732737 6480464 Benzo(a)pyrene inhibits the reaction [cobaltous chloride affects the localization of NCOA2 protein] CTD PMID:26350169 benzo[a]pyrene decreases expression ISO RGD:732737 6480464 Benzo(a)pyrene results in decreased expression of NCOA2 mRNA, Benzo(a)pyrene results in decreased expression of NCOA2 protein CTD PMID:20106945 more ... Benzyl parahydroxybenzoate multiple interactions ISO RGD:732737 6480464 benzylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 bezafibrate multiple interactions ISO RGD:732737 6480464 Bezafibrate promotes the reaction [PPARA protein binds to NCOA2 protein] CTD PMID:19263263 bicalutamide multiple interactions ISO RGD:732737 6480464 [IL6 protein results in increased expression of NCOA2 protein] which results in decreased susceptibility to bicalutamide CTD PMID:19240160 bisphenol A multiple interactions ISO RGD:732737 6480464 bisphenol A inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] more ... CTD PMID:10964929 more ... bisphenol A multiple interactions EXP 6480464 bisphenol A inhibits the reaction [Genistein results in decreased expression of NCOA2 protein], Genistein inhibits the reaction [bisphenol A results in increased expression of NCOA2 protein] CTD PMID:24884420 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of NCOA2 protein CTD PMID:19379760 more ... bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of NCOA2 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:732738 6480464 NCOA2 protein promotes the reaction [bisphenol A results in increased expression of ESR2 protein] CTD PMID:27634370 bisphenol F multiple interactions ISO RGD:732737 6480464 bisphenol F promotes the reaction [NCOA2 protein binds to THRB protein] CTD PMID:29146198 butamben multiple interactions ISO RGD:732737 6480464 butamben promotes the reaction [NR1I2.L protein binds to NCOA2 protein] CTD PMID:12198127 butanal decreases expression ISO RGD:732737 6480464 butyraldehyde results in decreased expression of NCOA2 mRNA CTD PMID:26079696 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of NCOA2 promoter CTD PMID:22457795 cadmium dichloride multiple interactions ISO RGD:732737 6480464 Cadmium Chloride promotes the reaction [VDR protein binds to NCOA2 protein] CTD PMID:21229763 calcitriol multiple interactions ISO RGD:732737 6480464 Calcitriol inhibits the reaction [NCOA2 protein binds to CYP7A1 mRNA] more ... CTD PMID:15578590 more ... calcitriol multiple interactions ISO RGD:732738 6480464 Calcitriol promotes the reaction [NCOA2 protein binds to CYP24A1 promoter], Calcitriol promotes the reaction [NCOA2 protein binds to SPP1 promoter] CTD PMID:15647825 calcitriol affects localization ISO RGD:732738 6480464 Calcitriol affects the localization of NCOA2 protein CTD PMID:15647825 calcitriol increases response to substance ISO RGD:732737 6480464 NCOA2 protein results in increased susceptibility to Calcitriol CTD PMID:25279795 chenodeoxycholic acid multiple interactions ISO RGD:732737 6480464 22 more ... CTD PMID:25257666 , PMID:27773686 cholesterol affects metabolic processing ISO RGD:732738 6480464 NCOA2 protein affects the metabolism of Cholesterol CTD PMID:14993927 cilnidipine multiple interactions ISO RGD:732737 6480464 cilnidipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 clevidipine multiple interactions ISO RGD:732737 6480464 clevidipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 cobalt dichloride decreases expression ISO RGD:732737 6480464 cobaltous chloride results in decreased expression of NCOA2 protein CTD PMID:26350169 cobalt dichloride multiple interactions ISO RGD:732737 6480464 Benzo(a)pyrene inhibits the reaction [cobaltous chloride affects the localization of NCOA2 protein] CTD PMID:26350169 coenzyme Q10 multiple interactions ISO RGD:732737 6480464 coenzyme Q10 inhibits the reaction [Lipopolysaccharides results in increased expression of NCOA2 mRNA] CTD PMID:21370964 coumestrol multiple interactions ISO RGD:732737 6480464 Coumestrol promotes the reaction [NCOA2 protein binds to ESR1 protein] CTD PMID:15084758 cyproterone acetate multiple interactions ISO RGD:732737 6480464 [Cyproterone Acetate binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NCOA2 protein modified form] more ... CTD PMID:15308689 , PMID:28751236 daidzein multiple interactions ISO RGD:732737 6480464 daidzein metabolite promotes the reaction [NCOA2 protein binds to ESR1 protein] CTD PMID:15084758 daunorubicin multiple interactions ISO RGD:732737 6480464 Daunorubicin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NR1H4 protein affects the localization of NCOA2 protein]] CTD PMID:25257666 dexamethasone increases expression ISO RGD:732737 6480464 Dexamethasone results in increased expression of NCOA2 mRNA CTD PMID:19022236 diarsenic trioxide multiple interactions ISO RGD:732737 6480464 Arsenic Trioxide inhibits the reaction [Metribolone promotes the reaction [NCOA2 protein binds to KLK3 promoter]] CTD PMID:19131511 dibutyl phthalate affects expression EXP 6480464 Dibutyl Phthalate affects the expression of NCOA2 mRNA CTD PMID:30934153 dicrotophos increases expression ISO RGD:732737 6480464 dicrotophos results in increased expression of NCOA2 mRNA CTD PMID:28302478 diethylstilbestrol affects binding ISO RGD:732737 6480464 [Diethylstilbestrol binds to ESR1 protein] which binds to NCOA2 protein, [Diethylstilbestrol binds to ESR2 protein] which binds to NCOA2 protein CTD PMID:15123288 diethylstilbestrol decreases expression ISO RGD:732738 6480464 Diethylstilbestrol results in decreased expression of NCOA2 protein CTD PMID:15019724 diethylstilbestrol multiple interactions ISO RGD:732737 6480464 Diethylstilbestrol promotes the reaction [ESR1 protein binds to NCOA2 protein] more ... CTD PMID:10964929 , PMID:15084758 dioxygen multiple interactions ISO RGD:732738 6480464 Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of NCOA2 mRNA] CTD PMID:22629407 dioxygen decreases expression ISO RGD:732737 6480464 Oxygen deficiency results in decreased expression of NCOA2 protein CTD PMID:26350169 dioxygen increases expression ISO RGD:732738 6480464 Oxygen deficiency results in increased expression of NCOA2 mRNA CTD PMID:22629407 , PMID:24205000 dioxygen affects methylation ISO RGD:732738 6480464 Oxygen deficiency affects the methylation of NCOA2 promoter CTD PMID:24205000 Doramectin multiple interactions ISO RGD:732737 6480464 doramectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 doxorubicin multiple interactions ISO RGD:732737 6480464 Doxorubicin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]], Doxorubicin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NR1H4 protein affects the localization of NCOA2 protein]] CTD PMID:25257666 , PMID:27773686 doxorubicin decreases expression ISO RGD:732737 6480464 Doxorubicin results in decreased expression of NCOA2 mRNA CTD PMID:29803840 elemental selenium multiple interactions ISO RGD:732737 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of NCOA2 mRNA CTD PMID:19244175 elemental selenium decreases expression ISO RGD:732737 6480464 Selenium results in decreased expression of NCOA2 mRNA CTD PMID:19244175 emamectin multiple interactions ISO RGD:732737 6480464 emamectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 emodin increases expression ISO RGD:732738 6480464 Emodin results in increased expression of NCOA2 mRNA CTD PMID:21319176 entinostat decreases expression ISO RGD:732737 6480464 entinostat results in decreased expression of NCOA2 mRNA CTD PMID:27188386 eprinomectin multiple interactions ISO RGD:732737 6480464 eprinomectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 ethanol affects splicing ISO RGD:732738 6480464 Ethanol affects the splicing of NCOA2 mRNA CTD PMID:30319688 Ethyl salicylate multiple interactions ISO RGD:732737 6480464 ethyl salicylate inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 ethylparaben multiple interactions ISO RGD:732737 6480464 ethyl-p-hydroxybenzoate inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 Falecalcitriol multiple interactions ISO RGD:732737 6480464 26 more ... CTD PMID:16059639 felodipine multiple interactions ISO RGD:732737 6480464 Felodipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 flavonol multiple interactions ISO RGD:732737 6480464 3-hydroxyflavone promotes the reaction [NCOA2 protein binds to NR1I2 protein] CTD PMID:26238175 fulvestrant multiple interactions ISO RGD:732737 6480464 fulvestrant inhibits the reaction [[TNF protein co-treated with resveratrol] promotes the reaction [NCOA2 protein binds to IL6 promoter]] CTD PMID:24771768 furan increases methylation EXP 6480464 furan results in increased methylation of NCOA2 gene CTD PMID:22079235 galangin multiple interactions ISO RGD:732737 6480464 galangin promotes the reaction [NCOA2 protein binds to NR1I2 protein] CTD PMID:26238175 geldanamycin increases expression ISO RGD:732737 6480464 geldanamycin results in increased expression of NCOA2 mRNA CTD PMID:26705709 genistein affects binding ISO RGD:732737 6480464 [Genistein binds to ESR1 protein] which binds to NCOA2 protein, [Genistein binds to ESR2 protein] which binds to NCOA2 protein CTD PMID:15123288 genistein multiple interactions EXP 6480464 bisphenol A inhibits the reaction [Genistein results in decreased expression of NCOA2 protein], Genistein inhibits the reaction [bisphenol A results in increased expression of NCOA2 protein] CTD PMID:24884420 genistein decreases expression EXP 6480464 Genistein results in decreased expression of NCOA2 protein CTD PMID:24884420 genistein multiple interactions ISO RGD:732738 6480464 NCOA2 protein promotes the reaction [Genistein results in increased expression of ESR2 protein alternative form], NCOA2 protein promotes the reaction [Genistein results in increased expression of ESR2 protein] CTD PMID:27634370 genistein multiple interactions ISO RGD:732737 6480464 Genistein promotes the reaction [ESR1 protein binds to NCOA2 protein] more ... CTD PMID:10964929 , PMID:15084758 guggulsterone multiple interactions ISO RGD:732737 6480464 pregna-4 more ... CTD PMID:27773686 hexadecanoic acid increases phosphorylation ISO RGD:732737 6480464 Palmitic Acid results in increased phosphorylation of NCOA2 protein CTD PMID:28073184 Isradipine multiple interactions ISO RGD:732737 6480464 Isradipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 ivermectin multiple interactions ISO RGD:732737 6480464 Ivermectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 lacidipine multiple interactions ISO RGD:732737 6480464 lacidipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of NCOA2 mRNA CTD PMID:22641619 lead diacetate multiple interactions ISO RGD:732737 6480464 lead acetate promotes the reaction [VDR protein binds to NCOA2 protein] CTD PMID:21229763 linalyl acetate multiple interactions ISO RGD:732737 6480464 NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 linoleic acid multiple interactions ISO RGD:732737 6480464 Linoleic Acid promotes the reaction [PPARA protein binds to NCOA2 protein] CTD PMID:19263263 lipopolysaccharide multiple interactions ISO RGD:732737 6480464 coenzyme Q10 inhibits the reaction [Lipopolysaccharides results in increased expression of NCOA2 mRNA] CTD PMID:21370964 lipopolysaccharide decreases expression ISO RGD:732738 6480464 Lipopolysaccharides results in decreased expression of NCOA2 mRNA CTD PMID:16847310 lipopolysaccharide increases expression ISO RGD:732737 6480464 Lipopolysaccharides results in increased expression of NCOA2 mRNA CTD PMID:21370964 methotrexate affects expression ISO RGD:732738 6480464 Methotrexate affects the expression of NCOA2 mRNA CTD PMID:18502557 methyl salicylate multiple interactions ISO RGD:732737 6480464 methyl salicylate inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 methylparaben multiple interactions ISO RGD:732737 6480464 methylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 methylseleninic acid multiple interactions ISO RGD:732737 6480464 methylselenic acid inhibits the reaction [Dihydrotestosterone promotes the reaction [NCOA2 protein binds to KLK3 promoter]] CTD PMID:16648561 mifepristone multiple interactions ISO RGD:732737 6480464 [Mifepristone binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 enhancer], [Mifepristone binds to AR protein] promotes the reaction [NCOA2 protein binds to KLK3 promoter] CTD PMID:15308689 milbemycin multiple interactions ISO RGD:732737 6480464 moxidectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 N-benzoyl-L-alanine multiple interactions ISO RGD:732737 6480464 N-benzoylalanine promotes the reaction [THRA protein binds to NCOA2 protein], N-benzoylalanine promotes the reaction [THRB protein binds to NCOA2 protein] CTD PMID:31566444 Nicardipine multiple interactions ISO RGD:732737 6480464 Nicardipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 nimodipine multiple interactions ISO RGD:732737 6480464 Nimodipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 p-tert-Amylphenol multiple interactions ISO RGD:732737 6480464 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA2 protein], 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA2 protein] CTD PMID:10964929 paracetamol decreases expression ISO RGD:732737 6480464 Acetaminophen results in decreased expression of NCOA2 mRNA CTD PMID:29067470 pentanal decreases expression ISO RGD:732737 6480464 pentanal results in decreased expression of NCOA2 mRNA CTD PMID:26079696 pirinixic acid multiple interactions ISO RGD:732737 6480464 pirinixic acid promotes the reaction [PPARA protein binds to NCOA2 protein] CTD PMID:19263263 potassium chromate decreases expression ISO RGD:732737 6480464 potassium chromate(VI) results in decreased expression of NCOA2 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:732737 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NCOA2 mRNA CTD PMID:22079256 progesterone multiple interactions ISO RGD:732738 6480464 NCOA2 protein affects the reaction [Progesterone results in decreased expression of BMP2 mRNA] more ... CTD PMID:17556502 progesterone increases expression ISO RGD:732738 6480464 Progesterone results in increased expression of NCOA2 protein CTD PMID:17556502 propylparaben multiple interactions ISO RGD:732737 6480464 propylparaben inhibits the reaction [afimoxifene inhibits the reaction [ESRRG protein binds to NCOA2 protein]] CTD PMID:23583298 quercetin decreases expression ISO RGD:732737 6480464 Quercetin results in decreased expression of NCOA2 mRNA CTD PMID:21632981 rac-lactic acid decreases expression ISO RGD:732737 6480464 Lactic Acid results in decreased expression of NCOA2 mRNA CTD PMID:30851411 raloxifene multiple interactions ISO RGD:732737 6480464 Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to IGF1 promoter], Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to PTGS2 promoter] CTD PMID:17872375 raloxifene increases expression ISO RGD:732737 6480464 Raloxifene Hydrochloride results in increased expression of NCOA2 protein CTD PMID:16739346 resveratrol multiple interactions ISO RGD:732737 6480464 fulvestrant inhibits the reaction [[TNF protein co-treated with resveratrol] promotes the reaction [NCOA2 protein binds to IL6 promoter]] more ... CTD PMID:15084758 , PMID:24771768 rifampicin multiple interactions ISO RGD:732737 6480464 Rifampin promotes the reaction [NCOA2 protein binds to HNF4A protein] CTD PMID:21292004 selenium atom multiple interactions ISO RGD:732737 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of NCOA2 mRNA CTD PMID:19244175 selenium atom decreases expression ISO RGD:732737 6480464 Selenium results in decreased expression of NCOA2 mRNA CTD PMID:19244175 succimer multiple interactions ISO RGD:732738 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of NCOA2 mRNA CTD PMID:21641980 tamoxifen multiple interactions ISO RGD:732737 6480464 Tamoxifen inhibits the reaction [ESR1 protein binds to NCOA2 protein], Tamoxifen promotes the reaction [NCOA2 protein binds to KLRC3 gene] CTD PMID:17395694 , PMID:23665804 tamoxifen increases expression ISO RGD:732737 6480464 Tamoxifen results in increased expression of NCOA2 mRNA, Tamoxifen results in increased expression of NCOA2 protein CTD PMID:16739346 , PMID:20332317 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of NCOA2 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NCOA2 mRNA] CTD PMID:31150632 thyroxine multiple interactions ISO RGD:732737 6480464 Thyroxine promotes the reaction [THRA protein binds to NCOA2 protein], Thyroxine promotes the reaction [THRB protein binds to NCOA2 protein] CTD PMID:31566444 titanium dioxide increases expression ISO RGD:732738 6480464 titanium dioxide results in increased expression of NCOA2 mRNA CTD PMID:23557971 toxaphene multiple interactions ISO RGD:732737 6480464 Toxaphene inhibits the reaction [NCOA2 protein results in increased activity of ESRRA protein] CTD PMID:10493499 trichostatin A affects expression ISO RGD:732737 6480464 trichostatin A affects the expression of NCOA2 mRNA CTD PMID:28542535 triclosan decreases expression ISO RGD:732737 6480464 Triclosan results in decreased expression of NCOA2 mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO RGD:732738 6480464 trimellitic anhydride results in increased expression of NCOA2 mRNA CTD PMID:19042947 troglitazone decreases expression ISO RGD:732738 6480464 troglitazone results in decreased expression of NCOA2 mRNA CTD PMID:28973697 tungsten decreases expression ISO RGD:732738 6480464 Tungsten results in decreased expression of NCOA2 mRNA CTD PMID:30912803 valproic acid decreases expression ISO RGD:732737 6480464 Valproic Acid results in decreased expression of NCOA2 mRNA CTD PMID:23179753 , PMID:28001369 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of NCOA2 mRNA CTD PMID:29427782 valproic acid increases methylation ISO RGD:732737 6480464 Valproic Acid results in increased methylation of NCOA2 gene CTD PMID:29154799 vitamin E multiple interactions ISO RGD:732737 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of NCOA2 mRNA CTD PMID:19244175 vitamin E decreases expression ISO RGD:732737 6480464 Vitamin E results in decreased expression of NCOA2 mRNA CTD PMID:19244175 vorinostat decreases expression ISO RGD:732737 6480464 vorinostat results in decreased expression of NCOA2 mRNA CTD PMID:27188386 zearalenone multiple interactions ISO RGD:732737 6480464 Zearalenone analog promotes the reaction [ESR1 protein binds to and results in increased activity of NCOA2 protein] more ... CTD PMID:15084758 , PMID:28807876
Biological Process cellular response to hormone stimulus IBA PANTHER:PTN000074430 more ... 13792537 PMID:21873635 GO_Central cellular response to Thyroglobulin triiodothyronine ISO RGD:732738 1624291 (MGI:MGI:5585573, PMID:24550004) RGD MGI:MGI:5585573 , PMID:24550004 cellular response to Thyroglobulin triiodothyronine IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 cerebellum development IEP 2293531 RGD circadian regulation of gene expression IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 circadian regulation of gene expression ISS UniProtKB:Q61026 1600115 GO_REF:0000024 UniProt GO_REF:0000024 circadian regulation of gene expression ISO RGD:732738 1624291 (MGI:MGI:5607392, PMID:24529706) RGD MGI:MGI:5607392 , PMID:24529706 circadian rhythm ISO RGD:732738 1624291 (PMID:24529706) RGD PMID:24529706 locomotor rhythm IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 locomotor rhythm ISO RGD:732738 1624291 (MGI:MGI:5607392, PMID:24529706) RGD MGI:MGI:5607392 , PMID:24529706 male gonad development IEP 1642058 RGD negative regulation of transcription by RNA polymerase II ISO RGD:732738 1624291 (MGI:MGI:81398, PMID:8643509) RGD MGI:MGI:81398 , PMID:8643509 negative regulation of transcription by RNA polymerase II IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of transcription, DNA-templated ISO RGD:732738 1624291 (MGI:MGI:81398, PMID:8643509) RGD MGI:MGI:81398 , PMID:8643509 positive regulation of female receptivity IMP 5688243 RGD positive regulation of glucocorticoid receptor signaling pathway IMP 5688226 RGD positive regulation of transcription by RNA polymerase II IMP 5688226 RGD positive regulation of transcription by RNA polymerase II IBA MGI:MGI:1276523 more ... 13792537 PMID:21873635 GO_Central positive regulation of transcription by RNA polymerase II IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of transcription by RNA polymerase II ISO RGD:732738 1624291 MGI:MGI:105043 (MGI:MGI:3522402 , PMID:15383530) RGD MGI:MGI:3522402 , PMID:15383530 regulation of gene expression ISO RGD:732738 1624291 MGI:MGI:2183799 (MGI:MGI:5570502 , PMID:24571987) RGD MGI:MGI:5570502 , PMID:24571987 regulation of glucose metabolic process IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of glucose metabolic process ISO RGD:732738 1624291 (MGI:MGI:3820385, PMID:19039140) RGD MGI:MGI:3820385 , PMID:19039140 regulation of transcription, DNA-templated ISO RGD:732738 1624291 (MGI:MGI:2154576 more ... RGD MGI:MGI:2154576 more ... response to progesterone ISO RGD:732738 1624291 MGI:MGI:2183799 (MGI:MGI:5570502 , PMID:24571987) RGD MGI:MGI:5570502 , PMID:24571987 response to progesterone IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 Cellular Component cytoplasm ISO RGD:732738 1624291 (MGI:MGI:2154576, PMID:11675124) RGD MGI:MGI:2154576 , PMID:11675124 cytoplasm IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 dendrite IDA 2326122 RGD dendritic spine IDA 5688258 RGD Golgi apparatus IDA 2326122 RGD microtubule IDA 2326122 RGD neuronal cell body IDA 2326122 RGD nuclear body IEA UniProtKB:Q15596 , ensembl:ENSP000003999681600115 GO_REF:0000107 Ensembl GO_REF:0000107 nuclear body ISO RGD:732737 1624291 RGD GO_REF:0000052 nucleoplasm ISO RGD:732737 1624291 RGD GO_REF:0000052 nucleus IDA 1642058 RGD nucleus IBA FB:FBgn0041092 more ... 13792537 PMID:21873635 GO_Central nucleus ISO RGD:732738 1624291 (MGI:MGI:2154576 more ... RGD MGI:MGI:2154576 more ... postsynaptic density IDA 2326122 RGD presynaptic active zone IDA 2326122 RGD protein-containing complex ISO RGD:732737 1624291 (PMID:15641800) RGD PMID:15641800 protein-containing complex IEA UniProtKB:Q15596 , ensembl:ENSP000003999681600115 GO_REF:0000107 Ensembl GO_REF:0000107 rough endoplasmic reticulum IDA 2326122 RGD Molecular Function aryl hydrocarbon receptor binding IEA UniProtKB:Q15596 , ensembl:ENSP000003999681600115 GO_REF:0000107 Ensembl GO_REF:0000107 aryl hydrocarbon receptor binding ISO RGD:732737 1624291 UniProtKB:P35869 (PMID:15641800) RGD PMID:15641800 chromatin binding ISO RGD:732738 1624291 (MGI:MGI:3611093, PMID:16109736) RGD MGI:MGI:3611093 , PMID:16109736 chromatin binding IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 DNA polymerase binding IPI RGD:3363 5688251 RGD estrogen receptor binding IPI RGD:736559 5688148 RGD estrogen receptor binding IPI RGD:69213 5688148 RGD glucocorticoid receptor binding IPI RGD:732227 633360 RGD nuclear hormone receptor binding ISO RGD:732737 1624291 UniProtKB:P35398 (PMID:10478845) RGD PMID:10478845 nuclear hormone receptor binding IBA FB:FBgn0041092 more ... 13792537 PMID:21873635 GO_Central nuclear receptor binding IPI RGD:732227 633360 RGD nuclear receptor binding IBA PANTHER:PTN000074430 more ... 13792537 PMID:21873635 GO_Central nuclear receptor binding IEA UniProtKB:Q15596 , ensembl:ENSP000003999681600115 GO_REF:0000107 Ensembl GO_REF:0000107 nuclear receptor binding ISO RGD:732737 1624291 UniProtKB:P24468 (PMID:18798693) RGD PMID:18798693 nuclear receptor binding IPI RGD:736295 633360 RGD nuclear receptor binding IPI RGD:731081 5688148 Pgr-B RGD nuclear receptor binding IPI RGD:736559 5688148 RGD nuclear receptor transcription coactivator activity ISO RGD:732737 1624291 (PMID:17363140) RGD PMID:17363140 nuclear receptor transcription coactivator activity IBA FB:FBgn0041092 more ... 13792537 PMID:21873635 GO_Central nuclear receptor transcription coactivator activity ISO RGD:732738 1624291 (MGI:MGI:3046495, PMID:15072553) RGD MGI:MGI:3046495 , PMID:15072553 PDZ domain binding IPI RGD:62004 2326120 RGD progesterone receptor binding IPI RGD:731081 5688148 Pgr-B RGD protein binding ISO RGD:732738 1624291 UniProtKB:O08785 more ... RGD MGI:MGI:1342114 more ... protein binding ISO RGD:732737 1624291 UniProtKB:O00482-1 more ... RGD PMID:11265755 more ... protein dimerization activity IEA InterPro:IPR011598 , InterPro:IPR036638 1600115 GO_REF:0000002 InterPro GO_REF:0000002 protein domain specific binding IEA UniProtKB:Q15596 , ensembl:ENSP000003999681600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein domain specific binding ISO RGD:732737 1624291 UniProtKB:P45481 (PMID:11583620) RGD PMID:11583620 protein-containing complex binding IPI RGD:1309046 more ... 5688233 RGD retinoic acid receptor binding IPI RGD:3535 5688233 in presence of retinoic acid RGD retinoid X receptor binding IPI RGD:3610 5688233 in presence of retinoic acid RGD RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO RGD:732738 1624291 (MGI:MGI:5585573, PMID:24550004) RGD MGI:MGI:5585573 , PMID:24550004 RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding ISO RGD:732738 1624291 (MGI:MGI:5585573, PMID:24550004) RGD MGI:MGI:5585573 , PMID:24550004 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 signaling receptor binding ISO RGD:732738 1624291 (MGI:MGI:81398, PMID:8643509) RGD MGI:MGI:81398 , PMID:8643509 thyroid hormone receptor binding IPI RGD:736295 633360 RGD thyroid hormone receptor coactivator activity ISO RGD:732738 1624291 (MGI:MGI:3046495, PMID:15072553) RGD MGI:MGI:3046495 , PMID:15072553 thyroid hormone receptor coactivator activity IEA UniProtKB:Q61026 , ensembl:ENSMUSP000000060371600115 GO_REF:0000107 Ensembl GO_REF:0000107 transcription coactivator activity ISS UniProtKB:Q61026 1600115 GO_REF:0000024 UniProt GO_REF:0000024 transcription coactivator activity ISO RGD:732738 1624291 MGI:MGI:105043 (MGI:MGI:2154576 more ... RGD MGI:MGI:2154576 more ... transcription factor binding ISO RGD:732738 1624291 UniProtKB:P51450-2 more ... RGD MGI:MGI:3688383 more ...
Gene-Chemical Interaction Annotations
