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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620108
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ncoa2
Name: nuclear receptor coactivator 2
Acc ID: CHEBI:31399
Term: cilnidipine
Definition: A diesterified 1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium channel blocker, it is used as an antihypertensive.
Chemical ID: MESH:C065927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ncoa2multiple interactionsISORGD:7327376480464CTDcilnidipine inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]

PMID:27773686
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.