ESR1 (estrogen receptor 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ESR1 (estrogen receptor 1) Homo sapiens
Analyze
Symbol: ESR1
Name: estrogen receptor 1
RGD ID: 736559
HGNC Page HGNC
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; general transcription initiation factor binding activity; and transcription coregulator binding activity. Involved in several processes, including cellular response to lipid; positive regulation of nitric oxide biosynthetic process; and regulation of RNA metabolic process. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in several cellular components, including nucleus; plasma membrane; and transcriptionally active chromatin. Part of transcription preinitiation complex. Implicated in several diseases, including artery disease (multiple); bone disease (multiple); breast cancer (multiple); type 2 diabetes mellitus; and vitiligo. Biomarker of several diseases, including breast cancer (multiple); lymphangioleiomyomatosis; osteoporosis; pulmonary hypertension; and reproductive organ cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686N23123; E2 receptor alpha; ER; ER-alpha; Era; ESR; ESRA; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor; estrogen receptor alpha 3*,4,5,6,7*/822 isoform; estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform; estrogen receptor alpha delta 3*,4,5,6,7*/819-2 isoform; estrogen receptor alpha delta 4 +49 isoform; estrogen receptor alpha delta 4*,5,6,7*/654 isoform; estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; ESTRR; NR3A1; nuclear receptor subfamily 3 group A member 1; oestrogen receptor alpha
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6151,656,691 - 152,129,619 (+)EnsemblGRCh38hg38GRCh38
GRCh386151,654,148 - 152,129,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376151,977,807 - 152,450,754 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366152,170,379 - 152,466,099 (+)NCBINCBI36hg18NCBI36
Build 346152,220,799 - 152,516,520NCBI
Celera6152,745,469 - 153,158,143 (+)NCBI
Cytogenetic Map6q25.1-q25.2NCBI
HuRef6149,573,851 - 149,986,188 (+)NCBIHuRef
CHM1_16152,275,698 - 152,688,511 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model