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Gene: Ncoa2 (nuclear receptor coactivator 2) Mus musculus
Symbol: Ncoa2
Name: nuclear receptor coactivator 2
Description: Exhibits several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and thyroid hormone receptor coactivator activity. Involved in several processes, including cellular response to Thyroglobulin triiodothyronine; circadian regulation of gene expression; and regulation of transcription by RNA polymerase II. Localizes to cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system; and sensory organ. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NCOA2 (nuclear receptor coactivator 2); PARTICIPATES IN aldosterone signaling pathway; altered androgen signaling pathway; androgen signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9530095N19; bHLHe75; D1Ertd433e; glucocorticoid receptor interacting protein 1; glucocorticoid receptor-interacting protein 1; GRIP-1; Grip1; KAT13C; NCoA-2; SRC-2; steroid receptor coactivator 2; TIF-2; TIF2; TIF2/GRIP-1; transcriptional intermediary factor 2
Homo sapiens (human) : NCOA2 (nuclear receptor coactivator 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ncoa2 (nuclear receptor coactivator 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncoa2 (nuclear receptor coactivator 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NCOA2 (nuclear receptor coactivator 2)
Canis lupus familiaris (dog) : NCOA2 (nuclear receptor coactivator 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncoa2 (nuclear receptor coactivator 2)
Sus scrofa (pig) : NCOA2 (nuclear receptor coactivator 2)
Chlorocebus sabaeus (African green monkey) : NCOA2 (nuclear receptor coactivator 2)
Heterocephalus glaber (naked mole-rat) : Ncoa2 (nuclear receptor coactivator 2)
more info ...
Related Pseudogenes: D030018L15Rik  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl113,139,105 - 13,374,083 (-)EnsemblGRCm38mm10GRCm38
GRCm38113,139,105 - 13,374,227 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37113,129,240 - 13,364,164 (-)NCBIGRCm37mm9NCBIm37
MGSCv36113,127,689 - 13,359,278 (-)NCBImm8
Celera113,103,226 - 13,334,430 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ncoa2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732738
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.