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Gene: Ncoa2 (nuclear receptor coactivator 2) Mus musculus
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Symbol: Ncoa2
Name: nuclear receptor coactivator 2
Description: Exhibits several functions, including RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and thyroid hormone receptor coactivator activity. Involved in several processes, including cellular response to Thyroglobulin triiodothyronine; circadian regulation of gene expression; and regulation of transcription by RNA polymerase II. Localizes to cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system; and sensory organ. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NCOA2 (nuclear receptor coactivator 2); PARTICIPATES IN aldosterone signaling pathway; altered androgen signaling pathway; androgen signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9530095N19; bHLHe75; D1Ertd433e; glucocorticoid receptor interacting protein 1; glucocorticoid receptor-interacting protein 1; GRIP-1; Grip1; KAT13C; NCoA-2; SRC-2; steroid receptor coactivator 2; TIF-2; TIF2; TIF2/GRIP-1; transcriptional intermediary factor 2
Orthologs:
Homo sapiens (human) : NCOA2 (nuclear receptor coactivator 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ncoa2 (nuclear receptor coactivator 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ncoa2 (nuclear receptor coactivator 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NCOA2 (nuclear receptor coactivator 2)
Canis lupus familiaris (dog) : NCOA2 (nuclear receptor coactivator 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ncoa2 (nuclear receptor coactivator 2)
Sus scrofa (pig) : NCOA2 (nuclear receptor coactivator 2)
Chlorocebus sabaeus (African green monkey) : NCOA2 (nuclear receptor coactivator 2)
Heterocephalus glaber (naked mole-rat) : Ncoa2 (nuclear receptor coactivator 2)
more info ...
Related Pseudogenes: D030018L15Rik  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl113,139,105 - 13,374,083 (-)EnsemblGRCm38mm10GRCm38
GRCm38113,139,105 - 13,374,227 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37113,129,240 - 13,364,164 (-)NCBIGRCm37mm9NCBIm37
MGSCv36113,127,689 - 13,359,278 (-)NCBImm8
Celera113,103,226 - 13,334,430 (-)NCBICelera
Cytogenetic Map1A3NCBI
cM Map14.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ncoa2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732738
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.