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Gene: PGR (progesterone receptor) Homo sapiens
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Symbol: PGR
Name: progesterone receptor
Description: Exhibits several functions, including ATPase binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and identical protein binding activity. Involved in negative regulation of gene expression and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin. Implicated in endometriosis; hyperprolactinemia; and obesity. Biomarker of ductal carcinoma in situ.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: NR3C3; nuclear receptor subfamily 3 group C member 3; PR
Orthologs:
Mus musculus (house mouse) : Pgr (progesterone receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pgr (progesterone receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pgr (progesterone receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : PGR (progesterone receptor)
Canis lupus familiaris (dog) : PGR (progesterone receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pgr (progesterone receptor)
Sus scrofa (pig) : PGR (progesterone receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811101,029,624 - 101,130,681 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711100,900,355 - 101,000,544 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611100,414,313 - 100,506,465 (-)NCBINCBI36hg18NCBI36
Build 3411100,414,312 - 100,506,465NCBI
Celera1198,069,715 - 98,169,894 (-)NCBI
Cytogenetic Map11q22.1NCBI
HuRef1196,837,449 - 96,937,628 (-)NCBIHuRef
CHM1_111100,783,609 - 100,883,736 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PGR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731081
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-10-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.