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Gene: ESR2 (estrogen receptor 2) Homo sapiens
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Symbol: ESR2
Name: estrogen receptor 2
RGD ID: 69213
Description: Exhibits several functions, including estrogen receptor activity; estrogen response element binding activity; and nuclear receptor activity. Involved in cellular response to lipid and regulation of transcription, DNA-templated. Localizes to mitochondrion and nucleus. Implicated in several diseases, including artery disease (multiple); arthritis (multiple); autoimmune hypersensitivity disease (multiple); hypospadias; and neurodegenerative disease (multiple). Biomarker of several diseases, including Alzheimer's disease; aortic valve stenosis; autoimmune hypersensitivity disease (multiple); inflammatory bowel disease (multiple); and urinary bladder cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ER beta; ER-BETA; Erb; ESR-BETA; ESRB; ESTRB; estrogen nuclear receptor beta variant a; estrogen nuclear receptor beta variant b; estrogen receptor 2 (ER beta); estrogen receptor beta; estrogen receptor beta 4; estrogen receptor beta splice variant, ERbeta2delta7; estrogen receptor beta splice variant, ERbeta4delta7; estrogen receptor beta splice variant, ERbeta6; estrogen receptor beta splice variant, ERbeta6delta7; estrogen receptor beta splice variant, ERbeta7; estrogen receptor beta splice variant, ERbeta7delta7; estrogen receptor beta splice variant, ERbetaEx. 4L; estrogen receptor beta splice variant, ERbetaEx. 6L; NR3A2; nuclear receptor subfamily 3 group A member 2; ODG8; oestrogen receptor beta
Orthologs:
Mus musculus (house mouse) : Esr2 (estrogen receptor 2 (beta))  MGI  Alliance
Rattus norvegicus (Norway rat) : Esr2 (estrogen receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Esr2 (estrogen receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ESR2 (estrogen receptor 2)
Canis lupus familiaris (dog) : ESR2 (estrogen receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Esr2 (estrogen receptor 2)
Sus scrofa (pig) : ESR2 (estrogen receptor 2)
Chlorocebus sabaeus (African green monkey) : ESR2 (estrogen receptor 2)
Heterocephalus glaber (naked mole-rat) : Esr2 (estrogen receptor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1464,084,232 - 64,338,112 (-)EnsemblGRCh38hg38GRCh38
GRCh381464,226,707 - 64,338,631 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371464,693,751 - 64,805,268 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361463,763,504 - 63,875,021 (-)NCBINCBI36hg18NCBI36
Build 341463,769,607 - 63,830,831NCBI
Celera1444,751,460 - 44,862,976 (-)NCBI
Cytogenetic Map14q23.2-q23.3NCBI
HuRef1444,866,333 - 44,977,880 (-)NCBIHuRef
CHM1_11464,633,252 - 64,745,077 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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RNA-SEQ Expression

Sequence

Nucleotide Sequences