1,2-dimethylhydrazine multiple interactions EXP 6480464 [APC protein affects the susceptibility to 1, 2-Dimethylhydrazine] which results in decreased expression of EPHA7 mRNA CTD PMID:27840820 1,2-dimethylhydrazine increases expression ISO RGD:732960 6480464 1, 2-Dimethylhydrazine results in increased expression of EPHA7 mRNA CTD PMID:22206623 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of EPHA7 mRNA CTD PMID:17108234 17beta-estradiol multiple interactions ISO RGD:732959 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of EPHA7 mRNA CTD PMID:20660070 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:732960 6480464 Tetrachlorodibenzodioxin results in decreased expression of EPHA7 mRNA CTD PMID:19933214 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of EPHA7 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732960 6480464 Tetrachlorodibenzodioxin affects the expression of EPHA7 mRNA CTD PMID:21570461 , PMID:24680724 2-methoxyethanol increases expression EXP 6480464 methyl cellosolve results in increased expression of EPHA7 mRNA CTD PMID:21061450 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of EPHA7 mRNA CTD PMID:24780913 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of EPHA7 mRNA CTD PMID:25825206 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of EPHA7 mRNA CTD PMID:31881176 aflatoxin B1 decreases methylation ISO RGD:732959 6480464 Aflatoxin B1 results in decreased methylation of EPHA7 gene CTD PMID:27153756 all-trans-retinoic acid increases expression ISO RGD:732960 6480464 Tretinoin results in increased expression of EPHA7 mRNA CTD PMID:16604517 all-trans-retinoic acid decreases expression ISO RGD:732959 6480464 Tretinoin results in decreased expression of EPHA7 mRNA CTD PMID:21934132 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EPHA7 mRNA CTD PMID:16483693 atrazine multiple interactions ISO RGD:732959 6480464 [Atrazine co-treated with Arsenates] results in increased expression of EPHA7 mRNA CTD PMID:18585445 belinostat increases expression ISO RGD:732959 6480464 belinostat results in increased expression of EPHA7 mRNA CTD PMID:26272509 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of EPHA7 mRNA CTD PMID:21839799 benzo[a]pyrene affects methylation ISO RGD:732959 6480464 Benzo(a)pyrene affects the methylation of EPHA7 promoter CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:732959 6480464 Benzo(a)pyrene results in increased methylation of EPHA7 exon CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:732960 6480464 Benzo(a)pyrene results in increased expression of EPHA7 mRNA CTD PMID:27195522 benzo[a]pyrene decreases expression ISO RGD:732959 6480464 Benzo(a)pyrene results in decreased expression of EPHA7 mRNA CTD PMID:22316170 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:732959 6480464 Diethylhexyl Phthalate results in decreased expression of EPHA7 mRNA CTD PMID:31163220 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EPHA7 mRNA CTD PMID:25181051 , PMID:30816183 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of EPHA7 promoter CTD PMID:22457795 clozapine increases expression ISO RGD:732960 6480464 Clozapine results in increased expression of EPHA7 mRNA CTD PMID:17266109 cocaine affects expression EXP 6480464 Cocaine affects the expression of EPHA7 mRNA CTD PMID:15691709 dexamethasone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in decreased expression of EPHA7 mRNA] CTD PMID:20032058 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of EPHA7 mRNA CTD PMID:20032058 diethyl malate affects expression ISO RGD:732960 6480464 diethyl malate affects the expression of EPHA7 mRNA CTD PMID:24814887 dorsomorphin multiple interactions ISO RGD:732959 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:732959 6480464 Doxorubicin results in decreased expression of EPHA7 mRNA CTD PMID:29803840 doxorubicin multiple interactions ISO RGD:732960 6480464 [Doxorubicin co-treated with Folic Acid] results in increased expression of EPHA7 mRNA CTD PMID:28608983 entinostat increases expression ISO RGD:732959 6480464 entinostat results in increased expression of EPHA7 mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:732959 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHA7 mRNA CTD PMID:27188386 ethanol affects splicing ISO RGD:732960 6480464 Ethanol affects the splicing of EPHA7 mRNA CTD PMID:30319688 fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of EPHA7 mRNA CTD PMID:30307764 folic acid multiple interactions ISO RGD:732960 6480464 [Doxorubicin co-treated with Folic Acid] results in increased expression of EPHA7 mRNA CTD PMID:28608983 folic acid decreases expression ISO RGD:732960 6480464 Folic Acid results in decreased expression of EPHA7 mRNA CTD PMID:25629700 fonofos increases methylation ISO RGD:732959 6480464 Fonofos results in increased methylation of EPHA7 promoter CTD PMID:22847954 genistein multiple interactions EXP 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of EPHA7 mRNA CTD PMID:21782745 genistein increases expression EXP 6480464 Genistein results in increased expression of EPHA7 mRNA CTD PMID:21782745 GW 4064 increases expression ISO RGD:732960 6480464 GW 4064 results in increased expression of EPHA7 mRNA CTD PMID:26655953 methoxychlor multiple interactions EXP 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of EPHA7 mRNA CTD PMID:21782745 methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of EPHA7 mRNA CTD PMID:21782745 methylmercury chloride decreases expression ISO RGD:732959 6480464 methylmercuric chloride results in decreased expression of EPHA7 mRNA CTD PMID:28001369 N-methyl-4-phenylpyridinium decreases expression ISO RGD:732959 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of EPHA7 mRNA CTD PMID:24810058 nickel atom multiple interactions ISO RGD:732959 6480464 trichostatin A inhibits the reaction [Nickel affects the expression of EPHA7 mRNA] CTD PMID:14575637 nickel atom decreases expression ISO RGD:732959 6480464 Nickel results in decreased expression of EPHA7 mRNA CTD PMID:24768652 , PMID:25583101 nickel atom affects expression ISO RGD:732959 6480464 Nickel affects the expression of EPHA7 mRNA CTD PMID:14575637 panobinostat increases expression ISO RGD:732959 6480464 panobinostat results in increased expression of EPHA7 mRNA CTD PMID:26272509 panobinostat multiple interactions ISO RGD:732959 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHA7 mRNA CTD PMID:27188386 parathion increases methylation ISO RGD:732959 6480464 Parathion results in increased methylation of EPHA7 promoter CTD PMID:22847954 pentanal decreases expression ISO RGD:732959 6480464 pentanal results in decreased expression of EPHA7 mRNA CTD PMID:26079696 ponatinib decreases activity ISO RGD:732959 6480464 ponatinib analog results in decreased activity of EPHA7 protein, ponatinib results in decreased activity of EPHA7 protein CTD PMID:19878872 , PMID:21561767 progesterone multiple interactions ISO RGD:732959 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of EPHA7 mRNA CTD PMID:20660070 SB 431542 multiple interactions ISO RGD:732959 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silver atom decreases expression ISO RGD:732959 6480464 Silver results in decreased expression of EPHA7 mRNA CTD PMID:26551752 silver(0) decreases expression ISO RGD:732959 6480464 Silver results in decreased expression of EPHA7 mRNA CTD PMID:26551752 sodium arsenite decreases methylation ISO RGD:732960 6480464 sodium arsenite results in decreased methylation of EPHA7 gene CTD PMID:32068019 sulforaphane decreases expression ISO RGD:732959 6480464 sulforafan results in decreased expression of EPHA7 mRNA CTD PMID:31838189 sunitinib increases expression ISO RGD:732959 6480464 Sunitinib results in increased expression of EPHA7 mRNA CTD PMID:31533062 terbufos increases methylation ISO RGD:732959 6480464 terbufos results in increased methylation of EPHA7 promoter CTD PMID:22847954 testosterone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in decreased expression of EPHA7 mRNA] CTD PMID:20032058 trichostatin A multiple interactions ISO RGD:732959 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:14575637 , PMID:27188386 trichostatin A decreases expression ISO RGD:732959 6480464 trichostatin A results in decreased expression of EPHA7 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A increases expression ISO RGD:732959 6480464 trichostatin A results in increased expression of EPHA7 mRNA CTD PMID:24935251 triclosan decreases expression ISO RGD:732959 6480464 Triclosan results in decreased expression of EPHA7 mRNA CTD PMID:30510588 tunicamycin decreases expression ISO RGD:732960 6480464 Tunicamycin results in decreased expression of EPHA7 mRNA CTD PMID:17127020 valproic acid decreases methylation ISO RGD:732959 6480464 Valproic Acid results in decreased methylation of EPHA7 gene CTD PMID:29154799 valproic acid multiple interactions ISO RGD:732959 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EPHA7 mRNA CTD PMID:27188386 valproic acid decreases expression ISO RGD:732959 6480464 Valproic Acid results in decreased expression of EPHA7 mRNA CTD PMID:23179753 , PMID:27188386 valproic acid increases expression ISO RGD:732959 6480464 Valproic Acid results in increased expression of EPHA7 mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO RGD:732959 6480464 Valproic Acid affects the expression of EPHA7 mRNA CTD PMID:25979313 valproic acid increases expression ISO RGD:732960 6480464 Valproic Acid results in increased expression of EPHA7 mRNA CTD PMID:19136453 warfarin affects response to substance ISO RGD:732959 6480464 EPHA7 promoter SNP affects the susceptibility to Warfarin CTD PMID:30357299 zinc sulfate increases expression ISO RGD:732959 6480464 Zinc Sulfate results in increased expression of EPHA7 mRNA CTD PMID:16330358
Biological Process apoptotic process IEA UniProtKB-KW:KW-0053 1600115 GO_REF:0000043 UniProt GO_REF:0000043 axon guidance IBA MGI:MGI:104770 more ... 13792537 PMID:21873635 GO_Central brain development ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 brain development ISO RGD:732960 1624291 (MGI:3582020, PMID:15902206) RGD MGI:3582020 , PMID:15902206 branching morphogenesis of a nerve ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 branching morphogenesis of a nerve ISO RGD:732960 1624291 MGI:3583808 (MGI:3583377 , PMID:15996548) RGD MGI:3583377 , PMID:15996548 ephrin receptor signaling pathway ISO RGD:732959 1624291 (PMID:17726105) RGD PMID:17726105 ephrin receptor signaling pathway ISO RGD:732960 1624291 (MGI:2182552, PMID:11089974) RGD MGI:2182552 , PMID:11089974 ephrin receptor signaling pathway ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 ephrin receptor signaling pathway ISS UniProtKB:Q15375 1600115 GO_REF:0000024 UniProt GO_REF:0000024 multicellular organism development IBA FB:FBgn0003733 more ... 13792537 PMID:21873635 GO_Central negative chemotaxis ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 negative regulation of collateral sprouting ISO RGD:732960 1624291 (MGI:5426777, PMID:19036963) RGD MGI:5426777 , PMID:19036963 negative regulation of synapse assembly ISO RGD:732960 1624291 (MGI:5426777, PMID:19036963) RGD MGI:5426777 , PMID:19036963 nephric duct morphogenesis ISO RGD:732960 1624291 MGI:98277 (MGI:5604037 , PMID:25139858) RGD MGI:5604037 , PMID:25139858 peptidyl-tyrosine phosphorylation IEA GO:0004713 1600115 GO_REF:0000108 GOC GO_REF:0000108 peptidyl-tyrosine phosphorylation IEA GO:0004714 1600115 GO_REF:0000108 GOC GO_REF:0000108 phosphorylation IDA 8554504 PMID:9883737 UniProt positive regulation of apoptotic process IMP 2301957 RGD positive regulation of kinase activity IBA PANTHER:PTN001230349 , UniProtKB:Q16832 13792537 PMID:21873635 GO_Central positive regulation of neuron apoptotic process ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 positive regulation of neuron apoptotic process ISO RGD:732960 1624291 (MGI:3582020, PMID:15902206) RGD MGI:3582020 , PMID:15902206 positive regulation of protein phosphorylation ISO RGD:732960 1624291 (MGI:5426777, PMID:19036963) RGD MGI:5426777 , PMID:19036963 regulation of cell-cell adhesion ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 regulation of cell-cell adhesion ISO RGD:732960 1624291 (MGI:2182552, PMID:11089974) RGD MGI:2182552 , PMID:11089974 regulation of cysteine-type endopeptidase activity involved in apoptotic process ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO RGD:732960 1624291 (MGI:3582020, PMID:15902206) RGD MGI:3582020 , PMID:15902206 regulation of ERK1 and ERK2 cascade ISO RGD:732959 1624291 (PMID:17726105) RGD PMID:17726105 regulation of ERK1 and ERK2 cascade ISS UniProtKB:Q15375 1600115 GO_REF:0000024 UniProt GO_REF:0000024 regulation of peptidyl-tyrosine phosphorylation ISO RGD:732959 1624291 (PMID:17726105) RGD PMID:17726105 regulation of peptidyl-tyrosine phosphorylation ISO RGD:732960 1624291 (MGI:2182552, PMID:11089974) RGD MGI:2182552 , PMID:11089974 regulation of peptidyl-tyrosine phosphorylation ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 regulation of peptidyl-tyrosine phosphorylation ISS UniProtKB:Q15375 1600115 GO_REF:0000024 UniProt GO_REF:0000024 regulation of postsynapse organization ISO RGD:732960 1624291 (MGI:5565127, PMID:24707048) RGD MGI:5565127 , PMID:24707048 regulation of protein autophosphorylation ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 regulation of protein autophosphorylation ISO RGD:732960 1624291 (MGI:2182552, PMID:11089974) RGD MGI:2182552 , PMID:11089974 retinal ganglion cell axon guidance ISO RGD:732960 1624291 MGI:3583808 (MGI:3583377 , PMID:15996548) RGD MGI:3583377 , PMID:15996548 transmembrane receptor protein tyrosine kinase signaling pathway IBA FB:FBgn0003366 more ... 13792537 PMID:21873635 GO_Central Cellular Component dendrite IDA 1300471 RGD glutamatergic synapse IDA 13702137 PMID:26780036 SynGO glutamatergic synapse ISO RGD:732960 1624291 (MGI:5565127, PMID:24707048) RGD MGI:5565127 , PMID:24707048 hippocampal mossy fiber to CA3 synapse IDA 13702137 PMID:26780036 SynGO integral component of plasma membrane IBA FB:FBgn0003366 more ... 13792537 PMID:21873635 GO_Central integral component of postsynaptic density membrane IDA 13702137 PMID:26780036 SynGO integral component of postsynaptic specialization membrane IDA 2301728 PMID:11414792 SynGO neuromuscular junction IDA 2301728 RGD neuron projection IBA MGI:MGI:109378 more ... 13792537 PMID:21873635 GO_Central neuronal cell body IDA 1300471 RGD plasma membrane ISO RGD:732959 1624291 (PMID:16862074) RGD PMID:16862074 postsynaptic membrane IDA 2301960 RGD receptor complex IBA FB:FBgn0015380 more ... 13792537 PMID:21873635 GO_Central Schaffer collateral - CA1 synapse IDA 13702137 PMID:26780036 SynGO Molecular Function ATP binding IEA UniProtKB-KW:KW-0067 1600115 GO_REF:0000043 UniProt GO_REF:0000043 axon guidance receptor activity ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 axon guidance receptor activity ISO RGD:732960 1624291 (MGI:5294300, PMID:16301174) RGD MGI:5294300 , PMID:16301174 chemorepellent activity ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 chemorepellent activity ISO RGD:732960 1624291 (MGI:3583377, PMID:15996548) RGD MGI:3583377 , PMID:15996548 ephrin receptor activity NAS 70732 RGD ephrin receptor binding IDA 2301959 RGD GPI-linked ephrin receptor activity ISS UniProtKB:Q61772 1600115 GO_REF:0000024 UniProt GO_REF:0000024 GPI-linked ephrin receptor activity ISO RGD:732960 1624291 (MGI:2182552, PMID:11089974) RGD MGI:2182552 , PMID:11089974 protein binding ISO RGD:732959 1624291 UniProtKB:P29317 , UniProtKB:P52793 (PMID:22036564) RGD PMID:22036564 protein binding ISO RGD:732960 1624291 UniProtKB:O08543 (MGI:2182552 more ... RGD MGI:2182552 more ... protein binding IPI UniProtKB:Q925T6 8554504 PMID:9883737 UniProt protein binding IPI UniProtKB:Q62083 8554504 PMID:9883737 UniProt protein binding IPI UniProtKB:O08992 8554504 PMID:9883737 UniProt protein tyrosine kinase activity IDA 8554504 PMID:9883737 UniProt transmembrane receptor protein tyrosine kinase activity IBA FB:FBgn0003366 more ... 13792537 PMID:21873635 GO_Central transmembrane-ephrin receptor activity IBA MGI:MGI:98277 more ... 13792537 PMID:21873635 GO_Central
Gene-Chemical Interaction Annotations
