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Gene: Rbm12b (RNA binding motif protein 12B) Rattus norvegicus

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Symbol:

Rbm12b

Name:

RNA binding motif protein 12B

RGD ID:

1307658

Description:

Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Orthologous to human RBM12B (RNA binding motif protein 12B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC313069; RGD1307658; RNA-binding protein 12B; RNA-binding protein 12B-A; similar to 3000004N20Rik protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RBM12B (RNA binding motif protein 12B)	HGNC	EggNOG, Ensembl, HomoloGene, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Rbm12b1 (RNA binding motif protein 12 B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rbm12b (RNA binding motif protein 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RBM12B (RNA binding motif protein 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RBM12B (RNA binding motif protein 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rbm12b (RNA binding motif protein 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RBM12B (RNA binding motif protein 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RBM12B (RNA binding motif protein 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rbm12b (RNA binding motif protein 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Rbm12b2 (RNA binding motif protein 12 B2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rbm12b1 (RNA binding motif protein 12 B1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RBM12B (RNA binding motif protein 12B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rbm12b (RNA binding motif protein 12B)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rbm-12	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG7879	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	rbm12ba	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	rbm12b.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rbm12b.3	Alliance	DIOPT (OMA\|OrthoFinder\|OrthoInspector)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	30,394,756 - 30,507,428 (+)	NCBI		GRCr8
mRatBN7.2	5	25,597,405 - 25,610,324 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	25,590,493 - 25,611,245 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	5	25,247,990 - 25,257,678 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	25,253,010 - 25,255,938 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	29,962,425 - 29,970,746 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	26,382,356 - 26,385,470 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	26,381,763 - 26,384,888 (+)	NCBI
Celera	5	24,920,046 - 24,928,196 (+)	NCBI		Celera
Cytogenetic Map	5	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rbm12b	Rat	myoepithelioma		ISO	RGD:1602033	8554872	ClinVar Annotator: match by term: Myoepithelial tumor	ClinVar

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rbm12b	Rat	(-)-alpha-phellandrene	decreases expression	ISO	RGD:1602033	6480464	alpha phellandrene results in decreased expression of RBM12B2 mRNA	CTD	PMID:25075043
Rbm12b	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of RBM12B mRNA	CTD	PMID:21215274\|PMID:33387578
Rbm12b	Rat	3,4-methylenedioxymethamphetamine	increases expression	ISO	RGD:1557899	6480464	N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of RBM12B mRNA	CTD	PMID:20188158
Rbm12b	Rat	4,4'-sulfonyldiphenol	decreases methylation	ISO	RGD:1557899	6480464	bisphenol S results in decreased methylation of RBM12B1 promoter	CTD	PMID:33297965
Rbm12b	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	RGD:1557899	6480464	bisphenol S results in increased expression of RBM12B1 mRNA	CTD	PMID:39298647
Rbm12b	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of RBM12B mRNA	CTD	PMID:30047161
Rbm12b	Rat	acrylamide	increases expression	ISO	RGD:1557899	6480464	Acrylamide results in increased expression of RBM12B1 mRNA	CTD	PMID:35032568
Rbm12b	Rat	aflatoxin B1	increases expression	ISO	RGD:1557899	6480464	Aflatoxin B1 results in increased expression of RBM12B mRNA	CTD	PMID:19770486
Rbm12b	Rat	alpha-phellandrene	decreases expression	ISO	RGD:1602033	6480464	alpha phellandrene results in decreased expression of RBM12B2 mRNA	CTD	PMID:25075043
Rbm12b	Rat	aristolochic acid A	decreases expression	ISO	RGD:1602033	6480464	aristolochic acid I results in decreased expression of RBM12B mRNA	CTD	PMID:33212167
Rbm12b	Rat	arsane	affects methylation	ISO	RGD:1602033	6480464	Arsenic affects the methylation of RBM12B gene	CTD	PMID:25304211
Rbm12b	Rat	arsane	multiple interactions	ISO	RGD:1602033	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Rbm12b	Rat	arsenic atom	affects methylation	ISO	RGD:1602033	6480464	Arsenic affects the methylation of RBM12B gene	CTD	PMID:25304211
Rbm12b	Rat	arsenic atom	multiple interactions	ISO	RGD:1602033	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Rbm12b	Rat	atrazine	decreases expression	ISO	RGD:1602033	6480464	Atrazine results in decreased expression of RBM12B mRNA	CTD	PMID:22378314
Rbm12b	Rat	benzo[a]pyrene	increases methylation	ISO	RGD:1602033	6480464	Benzo(a)pyrene results in increased methylation of RBM12B promoter	CTD	PMID:27901495
Rbm12b	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of RBM12B mRNA	CTD	PMID:30816183
Rbm12b	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of RBM12B mRNA	CTD	PMID:35192832
Rbm12b	Rat	bisphenol A	decreases expression	ISO	RGD:1557899	6480464	bisphenol A results in decreased expression of RBM12B1 mRNA	CTD	PMID:32156529
Rbm12b	Rat	bisphenol A	increases methylation	ISO	RGD:1602033	6480464	bisphenol A results in increased methylation of RBM12B gene	CTD	PMID:31601247
Rbm12b	Rat	bisphenol A	increases expression	ISO	RGD:1557899	6480464	bisphenol A results in increased expression of RBM12B1 mRNA	CTD	PMID:33221593
Rbm12b	Rat	bisphenol F	decreases expression	ISO	RGD:1557899	6480464	bisphenol F results in decreased expression of RBM12B1 mRNA	CTD	PMID:38685157
Rbm12b	Rat	cadmium atom	multiple interactions	ISO	RGD:1602033	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RBM12B more ...	CTD	PMID:35301059
Rbm12b	Rat	cadmium dichloride	decreases expression	ISO	RGD:1602033	6480464	Cadmium Chloride results in decreased expression of RBM12B mRNA	CTD	PMID:38568856
Rbm12b	Rat	cadmium dichloride	multiple interactions	ISO	RGD:1602033	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RBM12B more ...	CTD	PMID:35301059
Rbm12b	Rat	caffeine	decreases phosphorylation	ISO	RGD:1602033	6480464	Caffeine results in decreased phosphorylation of RBM12B protein	CTD	PMID:35688186
Rbm12b	Rat	carbon nanotube	increases expression	ISO	RGD:1557899	6480464	Nanotubes, Carbon analog results in increased expression of RBM12B1 mRNA; Nanotubes, Carbon results in increased more ...	CTD	PMID:25620056
Rbm12b	Rat	CGP 52608	multiple interactions	ISO	RGD:1602033	6480464	CGP 52608 promotes the reaction [RORA protein binds to RBM12B gene]	CTD	PMID:28238834
Rbm12b	Rat	chlorpyrifos	increases expression	ISO	RGD:1557899	6480464	Chlorpyrifos results in increased expression of RBM12B1 mRNA	CTD	PMID:37019170
Rbm12b	Rat	coumarin	affects phosphorylation	ISO	RGD:1602033	6480464	coumarin affects the phosphorylation of RBM12B protein	CTD	PMID:35688186
Rbm12b	Rat	cyclosporin A	decreases expression	ISO	RGD:1602033	6480464	Cyclosporine results in decreased expression of RBM12B mRNA	CTD	PMID:25562108
Rbm12b	Rat	deguelin	decreases expression	ISO	RGD:1602033	6480464	deguelin results in decreased expression of RBM12B mRNA	CTD	PMID:33512557
Rbm12b	Rat	dorsomorphin	multiple interactions	ISO	RGD:1602033	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Rbm12b	Rat	enzyme inhibitor	multiple interactions	ISO	RGD:1602033	6480464	[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ...	CTD	PMID:23301498
Rbm12b	Rat	folic acid	decreases expression	ISO	RGD:1557899	6480464	Folic Acid results in decreased expression of RBM12B mRNA	CTD	PMID:25629700
Rbm12b	Rat	formaldehyde	decreases expression	ISO	RGD:1602033	6480464	Formaldehyde results in decreased expression of RBM12B mRNA	CTD	PMID:20655997
Rbm12b	Rat	FR900359	affects phosphorylation	ISO	RGD:1602033	6480464	FR900359 affects the phosphorylation of RBM12B protein	CTD	PMID:37730182
Rbm12b	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of RBM12B mRNA	CTD	PMID:33387578
Rbm12b	Rat	GSK-J4	decreases expression	ISO	RGD:1602033	6480464	GSK-J4 results in decreased expression of RBM12B mRNA	CTD	PMID:29301935
Rbm12b	Rat	ivermectin	decreases expression	ISO	RGD:1602033	6480464	Ivermectin results in decreased expression of RBM12B protein	CTD	PMID:32959892
Rbm12b	Rat	ketamine	decreases expression	EXP		6480464	Ketamine results in decreased expression of RBM12B mRNA	CTD	PMID:20080153
Rbm12b	Rat	leflunomide	decreases expression	ISO	RGD:1602033	6480464	leflunomide results in decreased expression of RBM12B mRNA	CTD	PMID:28988120
Rbm12b	Rat	manganese atom	multiple interactions	ISO	RGD:1602033	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Rbm12b	Rat	manganese(0)	multiple interactions	ISO	RGD:1602033	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Rbm12b	Rat	manganese(II) chloride	multiple interactions	ISO	RGD:1602033	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Rbm12b	Rat	methidathion	decreases expression	ISO	RGD:1557899	6480464	methidathion results in decreased expression of RBM12B1 mRNA	CTD	PMID:34813904
Rbm12b	Rat	ozone	multiple interactions	ISO	RGD:1557899	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ...	CTD	PMID:34911549
Rbm12b	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of RBM12B mRNA	CTD	PMID:33387578
Rbm12b	Rat	phenobarbital	increases expression	ISO	RGD:1557899	6480464	Phenobarbital results in increased expression of RBM12B mRNA	CTD	PMID:19270015
Rbm12b	Rat	phenylmercury acetate	decreases expression	ISO	RGD:1602033	6480464	Phenylmercuric Acetate results in decreased expression of RBM12B mRNA	CTD	PMID:26272509
Rbm12b	Rat	phenylmercury acetate	multiple interactions	ISO	RGD:1602033	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Rbm12b	Rat	resveratrol	multiple interactions	ISO	RGD:1602033	6480464	[Plant Extracts co-treated with Resveratrol] results in increased expression of RBM12B mRNA	CTD	PMID:23557933
Rbm12b	Rat	rotenone	decreases expression	ISO	RGD:1602033	6480464	Rotenone results in decreased expression of RBM12B mRNA	CTD	PMID:33512557
Rbm12b	Rat	SB 431542	multiple interactions	ISO	RGD:1602033	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Rbm12b	Rat	serpentine asbestos	decreases methylation	ISO	RGD:1602033	6480464	Asbestos, Serpentine results in decreased methylation of RBM12B promoter	CTD	PMID:29626692
Rbm12b	Rat	sodium arsenite	multiple interactions	ISO	RGD:1602033	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Rbm12b	Rat	tebufenpyrad	decreases expression	ISO	RGD:1602033	6480464	4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of RBM12B mRNA	CTD	PMID:33512557
Rbm12b	Rat	tetrachloromethane	increases expression	ISO	RGD:1557899	6480464	Carbon Tetrachloride results in increased expression of RBM12B1 mRNA	CTD	PMID:27339419
Rbm12b	Rat	thiram	decreases expression	ISO	RGD:1602033	6480464	Thiram results in decreased expression of RBM12B mRNA	CTD	PMID:38568856
Rbm12b	Rat	titanium dioxide	decreases expression	ISO	RGD:1557899	6480464	titanium dioxide results in decreased expression of RBM12B1 mRNA	CTD	PMID:29264374
Rbm12b	Rat	trichostatin A	decreases expression	ISO	RGD:1602033	6480464	trichostatin A results in decreased expression of RBM12B mRNA	CTD	PMID:26272509
Rbm12b	Rat	trichostatin A	multiple interactions	ISO	RGD:1602033	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Rbm12b	Rat	triphenyl phosphate	affects expression	ISO	RGD:1602033	6480464	triphenyl phosphate affects the expression of RBM12B mRNA	CTD	PMID:37042841
Rbm12b	Rat	urethane	decreases expression	ISO	RGD:1602033	6480464	Urethane results in decreased expression of RBM12B mRNA	CTD	PMID:28818685
Rbm12b	Rat	valproic acid	decreases methylation	ISO	RGD:1602033	6480464	Valproic Acid results in decreased methylation of RBM12B gene	CTD	PMID:29154799
Rbm12b	Rat	valproic acid	multiple interactions	ISO	RGD:1602033	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Rbm12b	Rat	valproic acid	decreases expression	ISO	RGD:1602033	6480464	Valproic Acid results in decreased expression of RBM12B mRNA	CTD	PMID:23179753\|PMID:26272509\|PMID:27188386

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rbm12b	Rat	regulation of RNA splicing	involved_in	IBA	FB:FBgn0023441\|MGI:1917326\|PANTHER:PTN000360053\|UniProtKB:P31943\|UniProtKB:P52597\|UniProtKB:Q6NXG1\|UniProtKB:Q9H6T0	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rbm12b	Rat	nucleoplasm	is_active_in	IBA	PANTHER:PTN000360053\|RGD:620840\|UniProtKB:P31942\|UniProtKB:P31943\|UniProtKB:P52597\|UniProtKB:P55795\|UniProtKB:Q6NXG1\|UniProtKB:Q9H6T0\|UniProtKB:Q9NTZ6	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Rbm12b	Rat	ribonucleoprotein complex	part_of	IBA	PANTHER:PTN000359854\|UniProtKB:P31943\|UniProtKB:P52597\|UniProtKB:P55795	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rbm12b	Rat	nucleic acid binding	enables	IEA	InterPro:IPR035979	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Rbm12b	Rat	protein binding	enables	ISO	RGD:1602033	1624291	UniProtKB:O00555 PMID:21078624	RGD	PMID:21078624
Rbm12b	Rat	RNA binding	enables	IEA	UniProtKB-KW:KW-0694	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Rbm12b	Rat	RNA binding	enables	IEA	InterPro:IPR000504	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Rbm12b	Rat	RNA binding	enables	IEA	UniRule:UR000414619	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Rbm12b	Rat	RNA binding	enables	IBA	FB:FBgn0023441\|PANTHER:PTN000360053\|UniProtKB:P31943\|UniProtKB:P52597\|UniProtKB:Q12849\|UniProtKB:Q6NXG1\|UniProtKB:Q9H6T0	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:22658674	PMID:22681889

Rbm12b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	30,394,756 - 30,507,428 (+)	NCBI		GRCr8
mRatBN7.2	5	25,597,405 - 25,610,324 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	25,590,493 - 25,611,245 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	5	25,247,990 - 25,257,678 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	25,253,010 - 25,255,938 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	29,962,425 - 29,970,746 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	26,382,356 - 26,385,470 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	26,381,763 - 26,384,888 (+)	NCBI
Celera	5	24,920,046 - 24,928,196 (+)	NCBI		Celera
Cytogenetic Map	5	q13	NCBI

RBM12B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	93,728,155 - 93,741,009 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	93,728,155 - 93,741,017 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	94,740,383 - 94,753,237 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	94,812,904 - 94,822,400 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	90,929,789 - 90,939,285 (-)	NCBI		Celera
Cytogenetic Map	8	q22.1	NCBI
HuRef	8	89,951,263 - 89,960,755 (-)	NCBI		HuRef
CHM1_1	8	94,784,018 - 94,793,512 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	94,853,161 - 94,866,033 (-)	NCBI		T2T-CHM13v2.0

Rbm12b1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	12,138,957 - 12,148,922 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	12,140,264 - 12,146,731 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	12,138,957 - 12,148,922 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	12,140,264 - 12,146,731 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	12,067,264 - 12,073,892 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	12,067,464 - 12,073,878 (+)	NCBI		MGSCv36	mm8
Celera	3	28,599,613 - 28,600,101 (+)	NCBI		Celera
Cytogenetic Map	4	A1	NCBI
cM Map	4	5.58	NCBI

Rbm12b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	10,083,944 - 10,086,802 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955417	10,067,672 - 10,097,381 (-)	NCBI	ChiLan1.0	ChiLan1.0

RBM12B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	111,065,895 - 111,074,128 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	86,601,667 - 86,611,299 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	90,355,185 - 90,364,933 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	92,297,760 - 92,311,017 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

RBM12B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	38,631,313 - 38,641,998 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	38,634,742 - 38,637,723 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	38,792,185 - 38,804,225 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	38,834,294 - 38,846,338 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	38,839,007 - 38,841,988 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	38,848,170 - 38,860,213 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	38,842,743 - 38,854,785 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	39,284,239 - 39,296,282 (-)	NCBI		UU_Cfam_GSD_1.0

Rbm12b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	40,905,062 - 40,920,952 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936544	6,872,336 - 6,875,155 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936544	6,872,032 - 6,887,813 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RBM12B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	42,946,778 - 42,958,842 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	42,946,857 - 42,971,191 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	46,362,628 - 46,419,987 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RBM12B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	88,704,297 - 88,712,569 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	88,704,951 - 88,707,956 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	52,136,722 - 52,149,155 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rbm12b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624763	1,205,130 - 1,212,409 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624763	726,665 - 1,219,697 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Rbm12b
49 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	83
Count of miRNA genes:	75
Interacting mature miRNAs:	77
Transcripts:	ENSRNOT00000061333
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293666	Bmd38	Bone mineral density QTL 38	4.4		femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	5	8948228	53948228	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	18873947	74251464	Rat
1300117	Hrtrt8	Heart rate QTL 8	3.49		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	3844018	47869213	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9823266	99753708	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12789751	113558310	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
2312562	Pur18	Proteinuria QTL 18	2.6	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	5	2138965	32656739	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	2282226	69540447	Rat
61462	Niddm10	Non-insulin dependent diabetes mellitus QTL 10	3.9	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	5	5112159	47171491	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	12689285	57689285	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	21226744	66226744	Rat
1549901	Neudeg2	Neurodegradation QTL 2	4	0	nervous system integrity trait (VT:0010566)	mononuclear cell count (CMO:0002119)	5	24838710	44045280	Rat
2313085	Bss59	Bone structure and strength QTL 59	2.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	5	3844018	26141981	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	18873947	63873947	Rat

RH130399

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	25,596,917 - 25,597,097 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	25,255,968 - 25,256,147	NCBI	Rnor6.0
Rnor_6.0	5	25,244,601 - 25,244,780	NCBI	Rnor6.0
Rnor_5.0	5	29,970,391 - 29,970,570	UniSTS	Rnor5.0
Rnor_5.0	5	29,959,024 - 29,959,203	UniSTS	Rnor5.0
RGSC_v3.4	5	26,385,115 - 26,385,294	UniSTS	RGSC3.4
Celera	5	24,926,486 - 24,926,665	UniSTS
RH 3.4 Map	5	152.6	UniSTS
Cytogenetic Map	5	q13	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	10	49	113	91	90	59	25	59	6	217	96	93	45	60	31


RefSeq Transcripts	NM_001408811	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006225225	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006225227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237895	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237899	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287576	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287577	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000061333 ⟹ ENSRNOP00000058050

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	25,601,847 - 25,611,245 (+)	Ensembl
Rnor_6.0 Ensembl	5	25,253,010 - 25,255,938 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000087602 ⟹ ENSRNOP00000070736

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	25,602,653 - 25,611,152 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098214 ⟹ ENSRNOP00000086229

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	25,601,894 - 25,611,245 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101193 ⟹ ENSRNOP00000080062

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	25,605,323 - 25,610,962 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112220 ⟹ ENSRNOP00000095939

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	25,600,550 - 25,611,245 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114983 ⟹ ENSRNOP00000094131

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	25,590,493 - 25,611,245 (+)	Ensembl

RefSeq Acc Id:

NM_001408811 ⟹ NP_001395740

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	30,399,246 - 30,407,656 (+)	NCBI
mRatBN7.2	5	25,601,914 - 25,610,324 (+)	NCBI

RefSeq Acc Id:

XM_039110939 ⟹ XP_038966867

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	30,394,756 - 30,507,428 (+)	NCBI
mRatBN7.2	5	25,597,405 - 25,610,324 (+)	NCBI

RefSeq Acc Id:

XM_039110940 ⟹ XP_038966868

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	30,394,756 - 30,507,428 (+)	NCBI
mRatBN7.2	5	25,597,405 - 25,610,324 (+)	NCBI

RefSeq Acc Id:

XM_039110943 ⟹ XP_038966871

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	30,399,248 - 30,507,428 (+)	NCBI
mRatBN7.2	5	25,602,032 - 25,610,324 (+)	NCBI

RefSeq Acc Id:

XM_063287576 ⟹ XP_063143646

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	30,394,756 - 30,507,428 (+)	NCBI

RefSeq Acc Id:

XM_063287577 ⟹ XP_063143647

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	30,401,467 - 30,507,428 (+)	NCBI

RefSeq Acc Id:

XM_063287578 ⟹ XP_063143648

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	30,399,368 - 30,507,428 (+)	NCBI


Protein RefSeqs	NP_001395740	(Get FASTA)	NCBI Sequence Viewer
	XP_038966867	(Get FASTA)	NCBI Sequence Viewer
	XP_038966868	(Get FASTA)	NCBI Sequence Viewer
	XP_038966871	(Get FASTA)	NCBI Sequence Viewer
	XP_063143646	(Get FASTA)	NCBI Sequence Viewer
	XP_063143647	(Get FASTA)	NCBI Sequence Viewer
	XP_063143648	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000058050
	ENSRNOP00000058050.3
	ENSRNOP00000070736.2
	ENSRNOP00000080062.1
	ENSRNOP00000086229.1
	ENSRNOP00000094131.1
	ENSRNOP00000095939.1

Ensembl Acc Id:

ENSRNOP00000058050 ⟸ ENSRNOT00000061333

RefSeq Acc Id:	XP_038966867 ⟸ XM_039110939
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JYP3 (UniProtKB/TrEMBL), D3ZM54 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038966868 ⟸ XM_039110940
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JYP3 (UniProtKB/TrEMBL), D3ZM54 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038966871 ⟸ XM_039110943
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JYP3 (UniProtKB/TrEMBL), D3ZM54 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000080062 ⟸ ENSRNOT00000101193

Protein Domains

RRM

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JYP3-F1-model_v2	AlphaFold	A0A0G2JYP3	1-746	view protein structure
AF-D3ZM54-F1-model_v2	AlphaFold	D3ZM54	1-843	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-41911	BioCyc
Ensembl Genes	ENSRNOG00000016330	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000061333	ENTREZGENE
	ENSRNOT00000061333.4	UniProtKB/TrEMBL
	ENSRNOT00000087602.2	UniProtKB/TrEMBL
	ENSRNOT00000098214.1	UniProtKB/TrEMBL
	ENSRNOT00000101193.1	UniProtKB/TrEMBL
	ENSRNOT00000112220.1	UniProtKB/TrEMBL
	ENSRNOT00000114983.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
InterPro	ESRP	UniProtKB/TrEMBL
	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RBM12B_RRM2	UniProtKB/TrEMBL
	RRM4_RBM12B	UniProtKB/TrEMBL
	RRM_dom	UniProtKB/TrEMBL
NCBI Gene	313069	ENTREZGENE
PANTHER	HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED	UniProtKB/TrEMBL
Pfam	RRM_1	UniProtKB/TrEMBL
PhenoGen	Rbm12b	PhenoGen
PROSITE	RRM	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000016330	RatGTEx
SMART	RRM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/TrEMBL
UniProt	A0A0G2JYP3	ENTREZGENE
	D3ZM54	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A0G2JYP3	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Rbm12b	RNA binding motif protein 12B	RGD1307658_predicted	similar to 3000004N20Rik protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1307658_predicted	similar to 3000004N20Rik protein (predicted)	LOC313069_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC313069_predicted	similar to 3000004N20Rik protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar