Ube2k (ubiquitin-conjugating enzyme E2K) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ube2k (ubiquitin-conjugating enzyme E2K) Rattus norvegicus
Analyze
Symbol: Ube2k
Name: ubiquitin-conjugating enzyme E2K
RGD ID: 1311626
Description: Predicted to enable ubiquitin conjugating enzyme activity; ubiquitin protein ligase binding activity; and ubiquitin-ubiquitin ligase activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Predicted to be located in cytoplasm and filopodium tip. Predicted to be active in nucleus. Orthologous to human UBE2K (ubiquitin conjugating enzyme E2 K); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E2-25k; Hip2; huntingtin interacting protein 2; Hypg; Lig; LOC289623; ubiquitin-conjugating enzyme E2 K; ubiquitin-conjugating enzyme E2-25K; ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,011,681 - 43,077,825 (-)NCBIGRCr8
mRatBN7.21442,658,016 - 42,718,899 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,658,016 - 42,718,630 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,011,647 - 43,072,105 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01444,311,686 - 44,372,016 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,791,658 - 42,852,126 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01444,289,247 - 44,348,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,289,247 - 44,348,691 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,108,859 - 44,168,755 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,349,287 - 45,411,823 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11445,354,342 - 45,414,183 (-)NCBI
Celera1441,809,022 - 41,869,333 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
acetylsalicylic acid  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aminoglutethimide  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (EXP)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
chenodeoxycholic acid  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP,ISO)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
dieldrin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
mechlorethamine  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. E2-25K/Hip-2 regulates caspase-12 in ER stress-mediated Abeta neurotoxicity. Song S, etal., J Cell Biol. 2008 Aug 25;182(4):675-84. doi: 10.1083/jcb.200711066. Epub 2008 Aug 18.
Additional References at PubMed
PMID:14760703   PMID:16714285   PMID:17873885   PMID:18410486   PMID:18511602   PMID:18729231   PMID:20061386   PMID:23376485   PMID:24882218   PMID:26707646  


Genomics

Comparative Map Data
Ube2k
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,011,681 - 43,077,825 (-)NCBIGRCr8
mRatBN7.21442,658,016 - 42,718,899 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,658,016 - 42,718,630 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,011,647 - 43,072,105 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01444,311,686 - 44,372,016 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,791,658 - 42,852,126 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01444,289,247 - 44,348,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,289,247 - 44,348,691 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,108,859 - 44,168,755 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,349,287 - 45,411,823 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11445,354,342 - 45,414,183 (-)NCBI
Celera1441,809,022 - 41,869,333 (-)NCBICelera
Cytogenetic Map14p11NCBI
UBE2K
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38439,698,136 - 39,782,792 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl439,698,109 - 39,782,792 (+)EnsemblGRCh38hg38GRCh38
GRCh37439,699,756 - 39,784,412 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36439,376,266 - 39,457,977 (+)NCBINCBI36Build 36hg18NCBI36
Build 34439,522,436 - 39,604,148NCBI
Celera440,137,995 - 40,223,124 (+)NCBICelera
Cytogenetic Map4p14NCBI
HuRef439,024,547 - 39,109,580 (+)NCBIHuRef
CHM1_1439,699,339 - 39,784,070 (+)NCBICHM1_1
T2T-CHM13v2.0439,667,902 - 39,752,430 (+)NCBIT2T-CHM13v2.0
Ube2k
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39565,694,588 - 65,756,332 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl565,694,576 - 65,756,331 (+)EnsemblGRCm39 Ensembl
GRCm38565,537,245 - 65,598,989 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl565,537,233 - 65,598,988 (+)EnsemblGRCm38mm10GRCm38
MGSCv37565,928,500 - 65,990,228 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36565,816,406 - 65,878,063 (+)NCBIMGSCv36mm8
Celera562,815,933 - 62,878,205 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map533.72NCBI
Ube2k
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554437,618,379 - 7,656,305 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554437,618,379 - 7,655,542 (-)NCBIChiLan1.0ChiLan1.0
UBE2K
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2339,886,781 - 39,972,600 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1440,079,239 - 40,164,593 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0434,026,942 - 34,111,923 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1439,877,966 - 39,960,402 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl439,877,966 - 39,960,397 (+)Ensemblpanpan1.1panPan2
UBE2K
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1372,713,035 - 72,780,199 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl372,717,236 - 72,780,210 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha375,259,911 - 75,327,198 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0373,485,595 - 73,553,473 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl373,485,593 - 73,553,418 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1372,752,394 - 72,820,149 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0372,898,341 - 72,966,163 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0373,284,799 - 73,352,656 (-)NCBIUU_Cfam_GSD_1.0
Ube2k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528538,975,456 - 39,053,214 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364827,244,967 - 7,323,266 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364827,244,972 - 7,323,263 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBE2K
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl830,887,830 - 30,963,762 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1830,887,784 - 30,961,685 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2832,580,147 - 32,654,102 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UBE2K
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12710,535,091 - 10,618,659 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2710,539,402 - 10,618,573 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604756,921,431 - 57,007,501 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ube2k
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476127,205,034 - 27,276,884 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476127,205,034 - 27,277,016 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ube2k
167 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1026
Count of miRNA genes:346
Interacting mature miRNAs:477
Transcripts:ENSRNOT00000030485
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141854133263541332Rat
10755459Coatc15Coat color QTL 150.01681coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)141983694464836944Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143088377768757901Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143999825175582726Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat

Markers in Region
RH130202  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,659,388 - 42,659,586 (+)MAPPERmRatBN7.2
Rnor_6.01444,290,620 - 44,290,817NCBIRnor6.0
Rnor_5.01444,110,232 - 44,110,429UniSTSRnor5.0
RGSC_v3.41445,350,660 - 45,350,857UniSTSRGSC3.4
Celera1441,810,395 - 41,810,592UniSTS
Cytogenetic Map14p11UniSTS
RH141776  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21442,663,184 - 42,663,375 (+)MAPPERmRatBN7.2
Rnor_6.01444,294,416 - 44,294,606NCBIRnor6.0
Rnor_5.01444,114,028 - 44,114,218UniSTSRnor5.0
RGSC_v3.41445,354,456 - 45,354,646UniSTSRGSC3.4
Celera1441,814,191 - 41,814,381UniSTS
Cytogenetic Map14p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 57 41 19 41 5 7 74 35 41 11 5
Low 6 3 4 3
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000030485   ⟹   ENSRNOP00000032265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,658,016 - 42,718,554 (-)Ensembl
Rnor_6.0 Ensembl1444,289,247 - 44,348,691 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099891   ⟹   ENSRNOP00000085062
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,658,016 - 42,713,094 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103920   ⟹   ENSRNOP00000085882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,661,971 - 42,718,630 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105695   ⟹   ENSRNOP00000079243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,658,016 - 42,718,342 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116564   ⟹   ENSRNOP00000096375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,662,024 - 42,718,548 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118995   ⟹   ENSRNOP00000083068
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,662,172 - 42,718,554 (-)Ensembl
RefSeq Acc Id: NM_001106006   ⟹   NP_001099476
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,011,681 - 43,072,214 (-)NCBI
mRatBN7.21442,658,016 - 42,718,554 (-)NCBI
Rnor_6.01444,289,247 - 44,348,691 (-)NCBI
Rnor_5.01444,108,859 - 44,168,755 (-)NCBI
RGSC_v3.41445,349,287 - 45,411,823 (-)RGD
Celera1441,809,022 - 41,869,333 (-)RGD
Sequence:
RefSeq Acc Id: XM_039091716   ⟹   XP_038947644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,015,636 - 43,077,825 (-)NCBI
mRatBN7.21442,659,353 - 42,718,899 (-)NCBI
RefSeq Acc Id: XM_039091717   ⟹   XP_038947645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,015,636 - 43,072,270 (-)NCBI
mRatBN7.21442,659,353 - 42,718,548 (-)NCBI
RefSeq Acc Id: XM_063272925   ⟹   XP_063128995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,015,636 - 43,072,152 (-)NCBI
RefSeq Acc Id: XM_063272926   ⟹   XP_063128996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,015,636 - 43,071,961 (-)NCBI
RefSeq Acc Id: XM_063272927   ⟹   XP_063128997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81443,015,636 - 43,039,156 (-)NCBI
RefSeq Acc Id: NP_001099476   ⟸   NM_001106006
- UniProtKB: A6JDD4 (UniProtKB/TrEMBL),   A0A8I6AV01 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000032265   ⟸   ENSRNOT00000030485
RefSeq Acc Id: XP_038947644   ⟸   XM_039091716
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2L8 (UniProtKB/TrEMBL),   A0A8I6AV01 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947645   ⟸   XM_039091717
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZMB3 (UniProtKB/TrEMBL),   A6JDD3 (UniProtKB/TrEMBL),   A0A8I6AV01 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000079243   ⟸   ENSRNOT00000105695
RefSeq Acc Id: ENSRNOP00000083068   ⟸   ENSRNOT00000118995
RefSeq Acc Id: ENSRNOP00000085882   ⟸   ENSRNOT00000103920
RefSeq Acc Id: ENSRNOP00000096375   ⟸   ENSRNOT00000116564
RefSeq Acc Id: ENSRNOP00000085062   ⟸   ENSRNOT00000099891
RefSeq Acc Id: XP_063128995   ⟸   XM_063272925
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063128996   ⟸   XM_063272926
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063128997   ⟸   XM_063272927
- Peptide Label: isoform X3
Protein Domains
UBA   UBC core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZXS8-F1-model_v2 AlphaFold D3ZXS8 1-200 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699311
Promoter ID:EPDNEW_R9836
Type:initiation region
Name:Ube2k_1
Description:ubiquitin-conjugating enzyme E2K
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01444,348,663 - 44,348,723EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311626 AgrOrtholog
BioCyc Gene G2FUF-15749 BioCyc
BioCyc Pathway PWY-7511 [protein ubiquitination] BioCyc
BioCyc Pathway Image PWY-7511 BioCyc
Ensembl Genes ENSRNOG00000027088 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030485.6 UniProtKB/TrEMBL
  ENSRNOT00000099891.1 UniProtKB/TrEMBL
  ENSRNOT00000103920.1 UniProtKB/TrEMBL
  ENSRNOT00000105695.1 UniProtKB/TrEMBL
  ENSRNOT00000116564.1 UniProtKB/TrEMBL
  ENSRNOT00000118995.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro UBA-like UniProtKB/TrEMBL
  UBA/transl_elong_EF1B_N_euk UniProtKB/TrEMBL
  UBE2K_UBA UniProtKB/TrEMBL
  UBQ-conjugat_E2 UniProtKB/TrEMBL
  UBQ-conjugating_AS UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/TrEMBL
KEGG Report rno:289623 UniProtKB/TrEMBL
NCBI Gene 289623 ENTREZGENE
PANTHER E2 UBIQUITIN-CONJUGATING ENZYME UniProtKB/TrEMBL
  UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/TrEMBL
  UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/TrEMBL
  UBIQUITIN-CONJUGATING ENZYME E2 K UniProtKB/TrEMBL
Pfam UBA UniProtKB/TrEMBL
  UQ_con UniProtKB/TrEMBL
PhenoGen Ube2k PhenoGen
PROSITE UBA UniProtKB/TrEMBL
  UBIQUITIN_CONJUGAT_1 UniProtKB/TrEMBL
  UBIQUITIN_CONJUGAT_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027088 RatGTEx
SMART UBA UniProtKB/TrEMBL
  UBCc UniProtKB/TrEMBL
Superfamily-SCOP UBA_like UniProtKB/TrEMBL
  UBQ-conjugat/RWD-like UniProtKB/TrEMBL
UniProt A0A8I5ZMB3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYF7_RAT UniProtKB/TrEMBL
  A0A8I6A2L8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A356_RAT UniProtKB/TrEMBL
  A0A8I6AV01 ENTREZGENE, UniProtKB/TrEMBL
  A6JDD3 ENTREZGENE, UniProtKB/TrEMBL
  A6JDD4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZXS8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Ube2k  ubiquitin-conjugating enzyme E2K  Ube2k  ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Ube2k  ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)  Hip2  huntingtin interacting protein 2   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Hip2  huntingtin interacting protein 2   Hip2_predicted  huntingtin interacting protein 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Hip2_predicted  huntingtin interacting protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED