Agpat2 (1-acylglycerol-3-phosphate O-acyltransferase 2) - Rat Genome Database

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Gene: Agpat2 (1-acylglycerol-3-phosphate O-acyltransferase 2) Rattus norvegicus
Analyze
Symbol: Agpat2
Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
RGD ID: 1309229
Description: Predicted to enable 1-acylglycerol-3-phosphate O-acyltransferase activity. Involved in epidermis development and response to xenobiotic stimulus. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 1 and lipodystrophy. Orthologous to human AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2); PARTICIPATES IN glycerolipid metabolic pathway; glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta; 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta); LOC311821
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,814,924 - 29,826,569 (-)NCBIGRCr8
mRatBN7.239,416,837 - 9,428,567 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,416,843 - 9,428,371 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx312,481,959 - 12,492,601 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0321,065,209 - 21,075,851 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0319,320,532 - 19,331,176 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.034,044,741 - 4,055,384 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,044,542 - 4,055,806 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,404,488 - 9,415,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,769,863 - 4,781,045 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.134,769,881 - 4,809,158 (-)NCBI
Celera34,236,651 - 4,247,224 (-)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
amphetamine  (EXP)
anandamide  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
capecitabine  (ISO)
carbendazim  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenthion  (ISO)
flutamide  (EXP)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (EXP)
GW 4064  (ISO)
GW 7647  (ISO)
hexadecanoic acid  (ISO)
hydralazine  (ISO)
indometacin  (EXP)
inulin  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
methimazole  (EXP)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
oleic acid  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34. Agarwal AK, etal., Nat Genet. 2002 May;31(1):21-3. Epub 2002 Apr 22.
2. Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy. Cortes VA, etal., Cell Metab. 2009 Feb;9(2):165-76. doi: 10.1016/j.cmet.2009.01.002.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Expression and regulation of 1-acyl-sn-glycerol- 3-phosphate acyltransferases in the epidermis. Lu B, etal., J Lipid Res. 2005 Nov;46(11):2448-57. Epub 2005 Sep 8.
6. Proteomic analysis of rat hippocampus exposed to the antidepressant paroxetine. McHugh PC, etal., J Psychopharmacol. 2010 Aug;24(8):1243-51. doi: 10.1177/0269881109102786. Epub 2009 Apr 3.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9212163   PMID:9242711   PMID:15367102   PMID:15629135   PMID:16449762   PMID:19075029   PMID:21873652  


Genomics

Comparative Map Data
Agpat2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,814,924 - 29,826,569 (-)NCBIGRCr8
mRatBN7.239,416,837 - 9,428,567 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,416,843 - 9,428,371 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx312,481,959 - 12,492,601 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0321,065,209 - 21,075,851 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0319,320,532 - 19,331,176 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.034,044,741 - 4,055,384 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,044,542 - 4,055,806 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,404,488 - 9,415,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,769,863 - 4,781,045 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.134,769,881 - 4,809,158 (-)NCBI
Celera34,236,651 - 4,247,224 (-)NCBICelera
Cytogenetic Map3p13NCBI
AGPAT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,673,143 - 136,687,457 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,673,143 - 136,687,457 (-)EnsemblGRCh38hg38GRCh38
GRCh379139,567,595 - 139,581,909 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,687,416 - 138,701,732 (-)NCBINCBI36Build 36hg18NCBI36
Build 349136,843,432 - 136,857,712NCBI
Celera9110,081,330 - 110,095,564 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,027,535 - 109,041,933 (-)NCBIHuRef
CHM1_19139,716,530 - 139,730,723 (-)NCBICHM1_1
T2T-CHM13v2.09148,906,123 - 148,920,642 (-)NCBIT2T-CHM13v2.0
Agpat2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,483,069 - 26,494,429 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,483,069 - 26,494,429 (-)EnsemblGRCm39 Ensembl
GRCm38226,593,057 - 26,604,417 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,593,057 - 26,604,417 (-)EnsemblGRCm38mm10GRCm38
MGSCv37226,449,107 - 26,459,730 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36226,415,596 - 26,426,219 (-)NCBIMGSCv36mm8
Celera226,310,673 - 26,321,538 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.96NCBI
Agpat2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555134,135,460 - 4,149,677 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555134,142,074 - 4,145,097 (+)NCBIChiLan1.0ChiLan1.0
AGPAT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,696,619 - 2,710,862 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,699,026 - 2,713,196 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,749,195 - 107,763,033 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,722,914 - 136,737,286 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9136,722,914 - 136,737,286 (-)Ensemblpanpan1.1panPan2
AGPAT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,864,300 - 48,877,627 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,864,376 - 48,877,620 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha948,116,305 - 48,129,246 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,742,050 - 49,754,989 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,742,045 - 49,754,983 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,523,198 - 48,536,132 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,816,797 - 48,829,729 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,864,276 - 48,877,219 (+)NCBIUU_Cfam_GSD_1.0
Agpat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,176,086 - 202,203,966 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366691,195,365 - 1,202,042 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366691,185,204 - 1,198,972 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGPAT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21313,736,965 - 313,740,537 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGPAT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,511,063 - 1,525,146 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl121,511,124 - 1,525,440 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660583,743,355 - 3,757,442 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agpat2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,747,081 - 1,755,113 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247601,746,642 - 1,755,154 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Agpat2
37 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:318
Count of miRNA genes:184
Interacting mature miRNAs:205
Transcripts:ENSRNOT00000026408
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3653764510778823Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat

Markers in Region
RH141414  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.239,416,539 - 9,416,745 (+)MAPPERmRatBN7.2
Rnor_6.034,043,941 - 4,044,146NCBIRnor6.0
Rnor_5.039,404,189 - 9,404,394UniSTSRnor5.0
RGSC_v3.434,769,570 - 4,769,775UniSTSRGSC3.4
Celera34,235,851 - 4,236,056UniSTS
Cytogenetic Map3p13UniSTS
RH141422  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.239,416,883 - 9,417,082 (+)MAPPERmRatBN7.2
Rnor_6.034,044,285 - 4,044,483NCBIRnor6.0
Rnor_5.039,404,533 - 9,404,731UniSTSRnor5.0
RGSC_v3.434,769,914 - 4,770,112UniSTSRGSC3.4
Celera34,236,195 - 4,236,393UniSTS
Cytogenetic Map3p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000026408   ⟹   ENSRNOP00000026408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl39,416,843 - 9,428,371 (-)Ensembl
Rnor_6.0 Ensembl34,044,542 - 4,055,806 (-)Ensembl
RefSeq Acc Id: NM_001107821   ⟹   NP_001101291
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,814,924 - 29,826,157 (-)NCBI
mRatBN7.239,416,837 - 9,428,071 (-)NCBI
Rnor_6.034,044,741 - 4,055,384 (-)NCBI
Rnor_5.039,404,488 - 9,415,618 (-)NCBI
RGSC_v3.434,769,863 - 4,781,045 (-)RGD
Celera34,236,651 - 4,247,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105202   ⟹   XP_038961130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,814,924 - 29,826,569 (-)NCBI
mRatBN7.239,416,847 - 9,428,567 (-)NCBI
RefSeq Acc Id: XM_039105203   ⟹   XP_038961131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,814,924 - 29,826,119 (-)NCBI
mRatBN7.239,416,847 - 9,428,160 (-)NCBI
RefSeq Acc Id: XM_039105205   ⟹   XP_038961133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,814,924 - 29,825,762 (-)NCBI
mRatBN7.239,416,842 - 9,427,715 (-)NCBI
RefSeq Acc Id: XM_039105206   ⟹   XP_038961134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,814,924 - 29,825,660 (-)NCBI
mRatBN7.239,416,847 - 9,427,703 (-)NCBI
RefSeq Acc Id: XM_039105207   ⟹   XP_038961135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8329,814,924 - 29,826,493 (-)NCBI
mRatBN7.239,416,847 - 9,428,550 (-)NCBI
RefSeq Acc Id: NP_001101291   ⟸   NM_001107821
- Peptide Label: precursor
- UniProtKB: A6JTG5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000026408   ⟸   ENSRNOT00000026408
RefSeq Acc Id: XP_038961133   ⟸   XM_039105205
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038961130   ⟸   XM_039105202
- Peptide Label: isoform X1
- UniProtKB: D4AC45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961135   ⟸   XM_039105207
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038961131   ⟸   XM_039105203
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038961134   ⟸   XM_039105206
- Peptide Label: isoform X2
Protein Domains
Phospholipid/glycerol acyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AC45-F1-model_v2 AlphaFold D4AC45 1-265 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691910
Promoter ID:EPDNEW_R2435
Type:single initiation site
Name:Agpat2_1
Description:1-acylglycerol-3-phosphate O-acyltransferase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.034,055,773 - 4,055,833EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309229 AgrOrtholog
BioCyc Gene G2FUF-50360 BioCyc
BioCyc Pathway PWY-5667 [CDP-diacylglycerol biosynthesis I] BioCyc
  PWY-7411 [phosphatidate biosynthesis (yeast)] BioCyc
  PWY-7417 [phospholipid remodeling (phosphatidate, yeast)] BioCyc
  PWY-7782 [plasmalogen biosynthesis] BioCyc
  PWY-8053 [anandamide biosynthesis II] BioCyc
  TRIGLSYN-PWY [diacylglycerol and triacylglycerol biosynthesis] BioCyc
BioCyc Pathway Image PWY-5667 BioCyc
  PWY-7411 BioCyc
  PWY-7417 BioCyc
  PWY-7782 BioCyc
  PWY-8053 BioCyc
  TRIGLSYN-PWY BioCyc
Ensembl Genes ENSRNOG00000019466 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026408.8 UniProtKB/TrEMBL
InterPro Acyltransferase UniProtKB/TrEMBL
  AGP_acyltrans UniProtKB/TrEMBL
KEGG Report rno:311821 UniProtKB/TrEMBL
NCBI Gene 311821 ENTREZGENE
PANTHER 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE UniProtKB/TrEMBL
  1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE BETA UniProtKB/TrEMBL
Pfam Acyltransferase UniProtKB/TrEMBL
PhenoGen Agpat2 PhenoGen
RatGTEx ENSRNOG00000019466 RatGTEx
SMART PlsC UniProtKB/TrEMBL
Superfamily-SCOP Glycerol-3-phosphate (1)-acyltransferase UniProtKB/TrEMBL
UniProt A6JTG5 ENTREZGENE, UniProtKB/TrEMBL
  D4AC45 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-21 Agpat2  1-acylglycerol-3-phosphate O-acyltransferase 2  Agpat2  1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Agpat2  1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)   Agpat2_predicted  1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Agpat2_predicted  1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (predicted)      Symbol and Name status set to approved 70820 APPROVED