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Gene: Cx3cr1 (C-X3-C motif chemokine receptor 1) Rattus norvegicus
Symbol: Cx3cr1
Name: C-X3-C motif chemokine receptor 1
RGD ID: 620137
Description: Exhibits C-X3-C chemokine receptor activity. Involved in several processes, including positive regulation of neurogenesis; regulation of gene expression; and regulation of signal transduction. Localizes to several cellular components, including cell surface; neuronal cell body membrane; and perinuclear region of cytoplasm. Used to study glomerulonephritis; hepatopulmonary syndrome; and status epilepticus. Biomarker of several diseases, including anti-basement membrane glomerulonephritis; artery disease (multiple); borna disease; portal hypertension; and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including human immunodeficiency virus infectious disease; obesity; pulmonary hypertension; retinal disease (multiple); and systemic scleroderma. Orthologous to human CX3CR1 (C-X3-C motif chemokine receptor 1); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; acetamide; aflatoxin B1.
Type: protein-coding
Also known as: C-X3-C CKR-1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CX3C chemokine receptor 1; fractalkine receptor; Rbs11
Homo sapiens (human) : CX3CR1 (C-X3-C motif chemokine receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Cx3cr1 (chemokine (C-X3-C motif) receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cx3cr1 (C-X3-C motif chemokine receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CX3CR1 (C-X3-C motif chemokine receptor 1)
Canis lupus familiaris (dog) : CX3CR1 (C-X3-C motif chemokine receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cx3cr1 (C-X3-C motif chemokine receptor 1)
Sus scrofa (pig) : CX3CR1 (C-X3-C motif chemokine receptor 1)
Chlorocebus sabaeus (African green monkey) : CX3CR1 (C-X3-C motif chemokine receptor 1)
Heterocephalus glaber (naked mole-rat) : Cx3cr1 (C-X3-C motif chemokine receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08128,740,756 - 128,754,514 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,740,756 - 128,754,514 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08127,941,653 - 127,955,411 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,033,630 - 125,047,335 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18125,053,366 - 125,067,072 (-)NCBI
Celera8118,932,179 - 118,945,873 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cx3cr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620137
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.