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Gene: Dlg2 (discs large MAGUK scaffold protein 2) Rattus norvegicus
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Symbol: Dlg2
Name: discs large MAGUK scaffold protein 2
Description: Exhibits several functions, including PDZ domain binding activity; protein C-terminus binding activity; and protein heterodimerization activity. Involved in neuronal ion channel clustering and receptor clustering. Localizes to several cellular components, including the anchored component of postsynaptic density membrane; glutamatergic synapse; and neuron projection. Colocalizes with the voltage-gated potassium channel complex. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: channel-associated protein of synapse-110; chapsyn-110; discs large homolog 2; discs, large (Drosophila) homolog 2 (chapsyn-110); discs, large homolog 2; discs, large homolog 2 (Drosophila); disks large homolog 2; Dlgh2; postsynaptic density protein PSD-93; synaptic density protein PSD-93
Orthologs:
Homo sapiens (human) : DLG2 (discs large MAGUK scaffold protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Dlg2 (discs large MAGUK scaffold protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlg2 (discs large MAGUK scaffold protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DLG2 (discs large MAGUK scaffold protein 2)
Canis lupus familiaris (dog) : DLG2 (discs large MAGUK scaffold protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlg2 (discs large MAGUK scaffold protein 2)
Sus scrofa (pig) : DLG2 (discs large MAGUK scaffold protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01154,916,274 - 157,274,077 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01161,406,479 - 161,755,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01162,798,357 - 163,514,250 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41147,887,478 - 149,274,633 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11147,965,883 - 149,353,039 (+)NCBI
Celera1143,325,755 - 144,679,475 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dlg2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619895
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.