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Gene: Dlg2 (discs large MAGUK scaffold protein 2) Rattus norvegicus
Symbol: Dlg2
Name: discs large MAGUK scaffold protein 2
RGD ID: 619895
Description: Exhibits PDZ domain binding activity; protein C-terminus binding activity; and protein phosphatase binding activity. Involved in neuronal ion channel clustering and receptor clustering. Localizes to several cellular components, including dendrite; juxtaparanode region of axon; and neuronal cell body. Colocalizes with voltage-gated potassium channel complex. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: channel-associated protein of synapse-110; chapsyn-110; discs large homolog 2; discs, large (Drosophila) homolog 2 (chapsyn-110); discs, large homolog 2; discs, large homolog 2 (Drosophila); disks large homolog 2; Dlgh2; postsynaptic density protein PSD-93; synaptic density protein PSD-93
Homo sapiens (human) : DLG2 (discs large MAGUK scaffold protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Dlg2 (discs large MAGUK scaffold protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlg2 (discs large MAGUK scaffold protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DLG2 (discs large MAGUK scaffold protein 2)
Canis lupus familiaris (dog) : DLG2 (discs large MAGUK scaffold protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlg2 (discs large MAGUK scaffold protein 2)
Sus scrofa (pig) : DLG2 (discs large MAGUK scaffold protein 2)
Chlorocebus sabaeus (African green monkey) : DLG2 (discs large MAGUK scaffold protein 2)
Heterocephalus glaber (naked mole-rat) : Dlg2 (discs large MAGUK scaffold protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01154,916,274 - 157,274,077 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1156,552,328 - 157,269,747 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01162,798,357 - 163,514,250 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01161,406,479 - 161,755,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41147,887,478 - 149,274,633 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11147,965,883 - 149,353,039 (+)NCBI
Celera1143,325,755 - 144,679,475 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dlg2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619895
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.