Rf46 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Rf46 (Renal function QTL 46) Rattus norvegicus

Symbol: Rf46
Name: Renal function QTL 46
RGD ID: 1354623
Previously known as: QTL 58
Trait: blood creatinine amount   (VT:0005328)    
Measurement Type: plasma creatinine level   (CMO:0000537)    
LOD Score: 3.8
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81111,949,780 - 160,574,007RGD_MAPPER_PIPELINE
mRatBN7.21102,813,953 - 151,162,766RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01108,986,301 - 161,784,422RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01110,018,554 - 167,997,883RGDRnor5.0
RGSC_v3.41103,149,923 - 154,075,310RGDRGSC3.4
RGSC_v3.11103,228,034 - 154,153,698RGD
Cross Type: intercross
Strains Crossed: LH/Mav LN/Mav 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf46Rathypertension  IAGP 1302893 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf46Ratabnormal circulating creatinine level  QTM 1302893 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf46Ratplasma creatinine level  IDA 1302893 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf46Ratcontrol condition  IDA 1302893 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf46Ratautomated blood creatinine analysis  IDA 1302893 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf46RatLH/Mav  IEA 1302893 RGD 
Rf46RatLN/Mav  IEA 1302893 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rf46Ratblood creatinine amount  IDA 1302893 RGD 


#
Reference Title
Reference Citation
1. Mapping the genetic determinants of hypertension, metabolic diseases, and related phenotypes in the lyon hypertensive rat. Bilusic M, etal., Hypertension 2004 Nov;44(5):695-701. Epub 2004 Sep 27.


1 to 20 of 562 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1585050Ybx1-ps11Y box binding protein 1, pseudogene 111102914612102916158Rat
40964929LOC120100151U6 spliceosomal RNA1103004250103004356Rat
41048269LOC120099818uncharacterized LOC1200998181103031956103034632Rat
11465891LOC108349461uncharacterized LOC1083494611103443363103460555Rat
7512548LOC102552153uncharacterized LOC1025521531103510363103575329Rat
7518732LOC102552287uncharacterized LOC1025522871103583677103601779Rat
41329310Dnajb6-ps5DnaJ heat shock protein family (Hsp40) member B6, pseudogene 51103619537103621184Rat
1593285Hspd1-ps7heat shock protein family D (Hsp60) member 1, pseudogene 71103645663103648170Rat
2320865Atxn1-ps2ataxin 1, pseudogene 21103672445103674674Rat
6496810Ecsit-ps1ECSIT signaling integrator, pseudogene 11104502481104503645Rat
41166428LOC120100376small nucleolar RNA SNORA2/SNORA34 family1104515030104515165Rat
2320676Clp1-ps1cleavage factor polyribonucleotide kinase subunit 1, pseudogene 11105449881105451267Rat
6496163Luzp2leucine zipper protein 21105597291105983605Rat
41029545LOC120099819uncharacterized LOC1200998191105731072105743435Rat
2320478Hsp90ab1-ps1heat shock protein 90 alpha family class B member 1, pseudogene 11105948734105951090Rat
41153489LOC120100164U6 spliceosomal RNA1105964547105964651Rat
11409293LOC108348964uncharacterized LOC1083489641106125962106135332Rat
1590913Slc25a5-ps3solute carrier family 25 member 5, pseudogene 31106191309106192280Rat
1591914Ccdc137-ps1coiled-coil domain containing 137, pseudogene 11106199727106208762Rat
11393548LOC10834888060S ribosomal protein L34 pseudogene1106354560106354913Rat

1 to 20 of 562 rows
1 to 20 of 652 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
35220D1Rat291641102813953102814117Ratregion
1632415D1Got4102021102927108102927312Ratregion
1634688D1Got3081721103092085103092259Ratregion
1640935D1Got4431351103648288103648423Ratregion
5066814AU0481351261103829984103830110Ratregion
5066484AU0483291991104054313104054516Ratregion
5068440AU0471432811104315928104316209Ratregion
5500733A005V4014451104615367104616812Ratregion
1630332D1Got3142621105390396105390658Ratregion
5505165Trib12481105391709105391899Ratregion
1636200D1Got4062891105906176105906465Ratregion
5073760RH1376221641105981200105981364Ratregion
5049942RH1337701931105983271105983464Ratregion
5066524AU0483061081106016691106016801Ratregion
34381D1Mgh71411106047847106047988Ratregion
42272D1Rat4901871106130307106130494Ratregion
5505572UniSTS:4831566611106623061106623722Ratregion
5080766RH1417691921106625204106625396Ratregion
5084166AI2340921671106652090106652257Ratregion
5073066RH1372162021106671933106672135Ratregion
1 to 20 of 652 rows

Flank 1: (D1Rat29)
Rat AssemblyChrPosition (strand)Source
GRCr81111,949,780 - 111,949,944 (+)Marker Load Pipeline
mRatBN7.21102,813,953 - 102,814,117 (+)MAPPER
Rnor_6.01108,986,301 - 108,986,462NCBI
Rnor_5.01110,018,554 - 110,018,715UniSTS
RGSC_v3.41103,149,923 - 103,150,085RGD
RGSC_v3.41103,149,924 - 103,150,085UniSTS
RGSC_v3.11103,228,034 - 103,228,196RGD
Celera197,121,826 - 97,121,987UniSTS
RH 3.4 Map1951.6UniSTS
RH 3.4 Map1951.6RGD
SHRSP x BN Map151.4199UniSTS
SHRSP x BN Map151.4199RGD
FHH x ACI Map152.26RGD
Peak: (D1Rat43)
Rat AssemblyChrPosition (strand)Source
GRCr81146,080,545 - 146,080,661 (+)Marker Load Pipeline
Rnor_6.01144,634,295 - 144,634,401NCBI
RH 3.4 Map11099.7RGD
RH 3.4 Map11099.7UniSTS
SHRSP x BN Map168.8399UniSTS
SHRSP x BN Map168.8399RGD
FHH x ACI Map167.73RGD
Flank 2: (D1Rat140)
Rat AssemblyChrPosition (strand)Source
GRCr81160,573,753 - 160,574,007 (+)Marker Load Pipeline
mRatBN7.21151,162,512 - 151,162,766 (+)MAPPER
Rnor_6.01161,784,169 - 161,784,422NCBI
Rnor_5.01167,997,630 - 167,997,883UniSTS
RGSC_v3.41154,074,905 - 154,075,310RGD
RGSC_v3.41154,075,039 - 154,075,292UniSTS
RGSC_v3.11154,153,445 - 154,153,698RGD
Celera1149,267,898 - 149,268,151UniSTS
RH 3.4 Map11155.2RGD
RH 3.4 Map11155.2UniSTS
RH 2.0 Map1761.4RGD
SHRSP x BN Map176.83RGD
FHH x ACI Map169.95RGD
Cytogenetic Map1q32UniSTS


1 to 10 of 109 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
631569Bp93Blood pressure QTL 930.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1106047847121834139Rat
631570Bp94Blood pressure QTL 940.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123479780142990467Rat

1 to 10 of 109 rows


Database
Acc Id
Source(s)
NCBI Gene Rf46

Note Type Note Reference
qtl_cross_type intercross  
qtl_statistics_details linkage analysis performed with Mapmaker; parametric analysis used for traits with a normal distribution, for others nonparametric analysis used 1302893