Uae1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Uae1 (Urinary albumin excretion QTL 1) Rattus norvegicus

Symbol: Uae1
Name: Urinary albumin excretion QTL 1
RGD ID: 724521
Trait: urine albumin amount   (VT:0002871)    
Measurement Type: urine albumin excretion rate   (CMO:0000757)    
LOD Score: 3.8
P Value: 1.0E-4
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8199,645,382 - 182,701,046RGD_MAPPER_PIPELINE
mRatBN7.2190,508,614 - 173,018,436RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0194,201,400 - 184,846,632RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0195,301,716 - 205,161,264RGDRnor5.0
RGSC_v3.4190,282,040 - 185,923,619RGDRGSC3.4
RGSC_v3.1190,360,152 - 186,073,500RGD
Cross Type: intercross
Strains Crossed: MWF/FubRkb LEW/Rkb 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae1Ratcardiovascular system disease  IDA 634618 RGD 
Uae1Ratproteinuria  IDA 634618 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae1Ratincreased urine protein level  IDA 634618 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae1Raturine albumin excretion rate  IDA 634618 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae1Ratcontrol condition  IDA 634618 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae1Ratenzyme linked immunosorbent assay  IDA 634618 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae1RatLEW/Rkb  IEA 634618 RGD 
Uae1RatMWF/FubRkb  IEA 634618 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uae1Raturine albumin amount  IDA 634618 RGD 


#
Reference Title
Reference Citation
1. Genetic dissection of increased urinary albumin excretion in the munich wistar fromter rat. Schulz A, etal., J Am Soc Nephrol 2002 Nov;13(11):2706-14.


1 to 20 of 1489 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41103001LOC120100175U6 spliceosomal RNA19051132190511424Rat
1310358Uri1URI1, prefoldin-like chaperone19064639290704811Rat
11358405LOC108349566uncharacterized LOC10834956619070689690740913Rat
2294Ccne1cyclin E119078194790791188Rat
1591916Mrpl32-ps1mitochondrial ribosomal protein L32, pseudogene 119079444290798694Rat
41039507LOC120100209U7 small nuclear RNA19086153790861598Rat
1585208C1h19orf12similar to human chromosome 19 open reading frame 1219087357890887205Rat
41346041Rnu6-968RNA, U6 small nuclear 96819089044290890548Rat
1310544Plekhf1pleckstrin homology and FYVE domain containing 119090830490915862Rat
11381349LOC108349450uncharacterized LOC10834945019091046590926453Rat
11366552Gapdhl11glyceraldehyde-3-phosphate dehydrogenase like 1119094057290941452Rat
1305955Pop4POP4 homolog, ribonuclease P/MRP subunit19096002690968360Rat
1585163Uqcrb-ps1ubiquinol-cytochrome c reductase binding protein, pseudogene 119101732891017808Rat
9168486Rpl13a-ps3ribosomal protein L13A, pseudogene 319103627891036843Rat
1584053C1h2orf78l1similar to human chromosome 2 open reading frame 78 like 119105646491063841Rat
41322932LOC120100155U6 spliceosomal RNA19106146191061567Rat
11436011Zfp470zinc finger protein 47019106390591111883Rat
1584044Caap1-ps1caspase activity and apoptosis inhibitor 1, pseudogene 119106999391077845Rat
1583796Fam32al1family with sequence similarity 32, member A like 119107958991083390Rat
7598618LOC102548014uncharacterized LOC10254801419110575891128497Rat

1 to 20 of 1489 rows
1 to 20 of 1568 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10165D1Wox341341164747424164747558Ratregion
10273D1Smu111931168879333168879526Ratregion
10613D1Arb103931108698333108698726Ratregion
10839D1Wox1812019464443594644553Ratregion
11033D1Mgh191971152441635152441834Ratregion
11185D1Wox351541167512327167512481Ratregion
33806D1Mit241091163747690163747797Ratregion
33806D1Mit241091163747690163748014Ratregion
33870D1Mit171891126242834126243023Ratregion
33959D1Mit31371144267353144267490Ratregion
33959D1Mit31371144267353144267916Ratregion
34074D1Mgh81171153136852153136969Ratregion
34134D1Mgh11421118944747118944897Ratregion
34258D1Mgh3510719846236998462476Ratregion
34258D1Mgh3510719846236998463159Ratregion
34300D1Mgh261371172711200172711337Ratregion
34381D1Mgh71411106047847106047988Ratregion
34399D1Mgh91431172949660172949803Ratregion
11439D1Mit3018219449444094494763Ratregion
11439D1Mit3018219449457994494763Ratregion
1 to 20 of 1568 rows

Flank 1: (D1Rat27)
Rat AssemblyChrPosition (strand)Source
GRCr8199,645,382 - 99,645,535 (+)Marker Load Pipeline
mRatBN7.2190,508,614 - 90,508,767 (+)MAPPER
Rnor_6.0194,201,400 - 94,201,552NCBI
Rnor_5.0195,301,716 - 95,301,868UniSTS
RGSC_v3.4190,282,040 - 90,282,193RGD
RGSC_v3.4190,282,041 - 90,282,193UniSTS
RGSC_v3.1190,360,152 - 90,360,304RGD
Celera184,843,461 - 84,843,613UniSTS
RH 3.4 Map1886.8UniSTS
RH 3.4 Map1886.8RGD
RH 2.0 Map1578.1RGD
SHRSP x BN Map144.5299RGD
FHH x ACI Map148.9499RGD
Cytogenetic Map5q22UniSTS
Peak: (D1Rat38)
Rat AssemblyChrPosition (strand)Source
GRCr81141,173,126 - 141,173,303 (+)Marker Load Pipeline
mRatBN7.21131,763,437 - 131,763,614 (+)MAPPER
Rnor_6.01139,523,928 - 139,524,104NCBI
Rnor_5.01140,507,063 - 140,507,239UniSTS
RGSC_v3.41133,566,530 - 133,567,105RGD
RGSC_v3.41133,566,681 - 133,566,857UniSTS
RGSC_v3.11133,645,024 - 133,645,200RGD
Celera1123,840,438 - 123,840,614UniSTS
RH 3.4 Map11054.8UniSTS
RH 3.4 Map11054.8RGD
RH 2.0 Map1696.0RGD
SHRSP x BN Map166.5799RGD
FHH x ACI Map165.78RGD
Cytogenetic Map5q22UniSTS
Flank 2: (D1Rat216)
Rat AssemblyChrPosition (strand)Source
Rnor_5.01205,160,980 - 205,161,264NCBI
RGSC_v3.41185,923,336 - 185,923,619RGD
RGSC_v3.11186,073,217 - 186,073,500RGD
RH 2.0 Map1961.9RGD
SHRSP x BN Map191.4399RGD
FHH x ACI Map186.55RGD
Cytogenetic Map5q22UniSTS


1 to 10 of 150 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4889419Cstrr2Cold stress response QTL 20.05urine catecholamine amount (VT:0010502)absolute change in urine norepinephrine level (CMO:0001634)1155866514158592016Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat

1 to 10 of 150 rows


Database
Acc Id
Source(s)
NCBI Gene Uae1

Note Type Note Reference
qtl_cross_type intercross  
qtl_general associated with increased urinary albumin excretion at 14 weeks of age 634618