Siglec8 (sialic acid binding Ig-like lectin 8)

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Gene: Siglec8 (sialic acid binding Ig-like lectin 8) Rattus norvegicus

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Symbol:

Siglec8

Name:

sialic acid binding Ig-like lectin 8

Description:

ENCODES a protein that exhibits monosaccharide binding (ortholog); sialic acid binding (ortholog); INVOLVED IN cell adhesion (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of phagocytosis, engulfment (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine (ortholog); pirinixic acid (ortholog); potassium dichromate (ortholog)

Type:

gene

RefSeq Status:

MODEL

Also known as:

LOC292846; RGD1563073; similar to SIGLEC-like 1

Orthologs:

Homo sapiens (human) : SIGLEC8 (sialic acid binding Ig like lectin 8) HGNC Alliance
Mus musculus (house mouse) : Siglece (sialic acid binding Ig-like lectin E) MGI Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC103785254 (sialic acid-binding Ig-like lectin 8)
Canis lupus familiaris (dog) : LOC484344 (sialic acid-binding Ig-like lectin 13)

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Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	1	99,576,946 - 99,587,441 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	100,645,666 - 100,656,065 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	94,062,030 - 94,071,181 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	1	88,361,882 - 88,372,377 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

JBrowse:

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Model

Annotation (Toggle Annotation Detail/Summary View)

Gene-Chemical Interaction Annotations

Gene Ontology Annotations

References - curated

References - uncurated

RGD Disease Portals

Genomics

Comparative Map Data

QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences

Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links

Nomenclature History

More on Siglec8
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	1563073
Created:	2006-02-09
Species:	Rattus norvegicus
Last Modified:	2018-08-14
Status:	ACTIVE

Functional Annotation unavailable	Annotation Distribution unavailable	Genomic Variants unavailble for Mouse Genomic Variants unavailable
Functional Annotation	Annotation Distribution	Genomic Variants

Protein-Protein Interactions unavailable	Genome Viewer unavailable	Damaging Variants unavailble for Mouse Damaging Variants unavailable
Protein-Protein Interactions	Genome Viewer	Damaging Variants

Annotation Comparison unavailable	OLGA unavailable
Annotation Comparison	OLGA	Excel (Download)