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Gene: Siglec8 (sialic acid binding Ig-like lectin 8) Rattus norvegicus
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Symbol: Siglec8
Name: sialic acid binding Ig-like lectin 8
Description: Predicted to have monosaccharide binding activity and sialic acid binding activity. Predicted to be involved in cell adhesion; negative regulation of inflammatory response; and negative regulation of phagocytosis, engulfment. Predicted to localize to external side of plasma membrane. Orthologous to human SIGLEC8 (sialic acid binding Ig like lectin 8); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); benzalkonium chloride (ortholog).
Type: gene
RefSeq Status: MODEL
Also known as: LOC292846; RGD1563073; similar to SIGLEC-like 1
Orthologs:
Homo sapiens (human) : SIGLEC8 (sialic acid binding Ig like lectin 8)  HGNC  Alliance
Mus musculus (house mouse) : Siglece (sialic acid binding Ig-like lectin E)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC103785254 (sialic acid-binding Ig-like lectin 8)
Canis lupus familiaris (dog) : LOC484344 (sialic acid-binding Ig-like lectin 13)
Heterocephalus glaber (naked mole-rat) : Siglec8 (sialic acid binding Ig like lectin 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0199,576,946 - 99,587,441 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,578,372 - 99,587,205 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01100,645,666 - 100,656,065 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,062,030 - 94,071,181 (-)NCBIRGSC3.4rn4RGSC3.4
Celera188,361,882 - 88,372,377 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Siglec8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563073
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.