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Gene: Gabrb3 (gamma-aminobutyric acid type A receptor beta 3 subunit) Rattus norvegicus
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Symbol: Gabrb3
Name: gamma-aminobutyric acid type A receptor beta 3 subunit
Description: Exhibits AP-2 adaptor complex binding activity; GABA-A receptor activity; and chloride channel activity. Predicted to contribute to extracellular ligand-gated ion channel activity. Involved in GABAergic synaptic transmission. Localizes to several cellular components, including the GABA-ergic synapse; inhibitory synapse; and integral component of postsynaptic specialization membrane. Human ortholog(s) of this gene implicated in childhood absence epilepsy and early infantile epileptic encephalopathy 43. Orthologous to human GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GABA(A) receptor subunit beta-3; GABA-alpha receptor beta-3 subunit; gamma-aminobutyric acid (GABA) A receptor, beta 3; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 3; Gamma-aminobutyric acid receptor beta 3; gamma-aminobutyric acid receptor subunit beta-3; gamma-aminobutyric acid receptor, subunit beta 3; testis gamma-aminobutyric acid receptor subunit beta 3
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01113,034,251 - 113,265,364 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01114,042,551 - 114,275,043 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41109,047,399 - 109,277,756 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11109,125,741 - 109,356,099 (+)NCBI
Celera1102,635,270 - 102,866,355 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gabrb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2651
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.