Plekhf1 (pleckstrin homology and FYVE domain containing 1) - Rat Genome Database

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Gene: Plekhf1 (pleckstrin homology and FYVE domain containing 1) Rattus norvegicus
Analyze
Symbol: Plekhf1
Name: pleckstrin homology and FYVE domain containing 1
RGD ID: 1310544
Description: Predicted to enable phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in several processes, including endosome to lysosome transport; positive regulation of intrinsic apoptotic signaling pathway; and protein localization to plasma membrane. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be active in early endosome and lysosome. Predicted to colocalize with endosome. Orthologous to human PLEKHF1 (pleckstrin homology and FYVE domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC308543; PH domain-containing family F member 1; pleckstrin homology domain containing, family F (with FYVE domain) member 1; pleckstrin homology domain-containing family F member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81100,045,340 - 100,046,817 (-)NCBIGRCr8
mRatBN7.2190,908,304 - 90,915,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl190,904,742 - 90,915,820 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx196,304,107 - 96,305,583 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01104,769,821 - 104,771,297 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0198,062,634 - 98,064,111 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0194,609,041 - 94,616,565 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl194,609,377 - 94,610,854 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0195,700,153 - 95,707,361 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4190,697,260 - 90,698,737 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1190,775,372 - 90,776,840 (-)NCBI
Celera185,240,535 - 85,242,012 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-colchicine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
adenine  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
Cuprizon  (EXP)
cypermethrin  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
dibutyl phthalate  (ISO)
dieldrin  (EXP)
dimethyl sulfoxide  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
ferric oxide  (ISO)
fluoranthene  (ISO)
flutamide  (EXP)
furan  (EXP)
glyphosate  (ISO)
indometacin  (ISO)
methamphetamine  (EXP)
methyl methanesulfonate  (ISO)
nickel dichloride  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
SCH 23390  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulindac  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:22115783  


Genomics

Comparative Map Data
Plekhf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81100,045,340 - 100,046,817 (-)NCBIGRCr8
mRatBN7.2190,908,304 - 90,915,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl190,904,742 - 90,915,820 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx196,304,107 - 96,305,583 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01104,769,821 - 104,771,297 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0198,062,634 - 98,064,111 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0194,609,041 - 94,616,565 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl194,609,377 - 94,610,854 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0195,700,153 - 95,707,361 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4190,697,260 - 90,698,737 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1190,775,372 - 90,776,840 (-)NCBI
Celera185,240,535 - 85,242,012 (-)NCBICelera
Cytogenetic Map1q21NCBI
PLEKHF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381929,665,461 - 29,675,477 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1929,665,459 - 29,675,477 (+)EnsemblGRCh38hg38GRCh38
GRCh371930,156,368 - 30,166,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361934,848,167 - 34,858,224 (+)NCBINCBI36Build 36hg18NCBI36
Build 341934,847,802 - 34,858,204NCBI
Celera1926,854,527 - 26,864,585 (+)NCBICelera
Cytogenetic Map19q12NCBI
HuRef1926,668,787 - 26,678,845 (+)NCBIHuRef
CHM1_11930,157,659 - 30,167,716 (+)NCBICHM1_1
T2T-CHM13v2.01932,191,180 - 32,201,225 (+)NCBIT2T-CHM13v2.0
Plekhf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39737,920,078 - 37,927,418 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl737,916,396 - 37,927,440 (-)EnsemblGRCm39 Ensembl
GRCm38738,220,654 - 38,227,994 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl738,216,972 - 38,228,016 (-)EnsemblGRCm38mm10GRCm38
MGSCv37739,005,673 - 39,013,013 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36737,929,761 - 37,937,047 (-)NCBIMGSCv36mm8
Celera733,384,111 - 33,391,399 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map725.36NCBI
Plekhf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554687,934,024 - 7,943,499 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554687,934,024 - 7,943,499 (-)NCBIChiLan1.0ChiLan1.0
PLEKHF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22035,646,442 - 35,656,852 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11937,643,651 - 37,653,763 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01926,593,833 - 26,604,514 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11935,354,315 - 35,364,366 (+)NCBIpanpan1.1PanPan1.1panPan2
PLEKHF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11121,776,122 - 121,802,881 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1121,781,181 - 121,782,578 (-)NCBICanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1121,781,181 - 121,782,578 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01122,402,959 - 122,431,800 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1122,409,980 - 122,411,377 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11121,982,589 - 122,011,226 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01121,595,581 - 121,618,885 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,654,118 - 122,682,943 (-)NCBIUU_Cfam_GSD_1.0
Plekhf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093495,976,223 - 5,987,835 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365705,658,052 - 5,666,358 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365705,658,052 - 5,666,711 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl639,786,199 - 39,797,583 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1639,786,201 - 39,797,578 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2635,145,695 - 35,157,120 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1624,732,774 - 24,743,636 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl624,742,024 - 24,742,863 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660732,264,800 - 2,275,582 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekhf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247944,843,635 - 4,852,346 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247944,843,342 - 4,852,346 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plekhf1
28 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:61
Count of miRNA genes:59
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000020383
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat

Markers in Region
RH129691  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2190,908,685 - 90,908,890 (+)MAPPERmRatBN7.2
Rnor_6.0194,609,423 - 94,609,627NCBIRnor6.0
Rnor_5.0195,700,222 - 95,700,426UniSTSRnor5.0
RGSC_v3.4190,697,308 - 90,697,512UniSTSRGSC3.4
Celera185,240,583 - 85,240,787UniSTS
RH 3.4 Map1882.2UniSTS
Cytogenetic Map1q22UniSTS
RH137172  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2190,908,725 - 90,908,919 (+)MAPPERmRatBN7.2
Rnor_6.0194,609,463 - 94,609,656NCBIRnor6.0
Rnor_5.0195,700,262 - 95,700,455UniSTSRnor5.0
RGSC_v3.4190,697,348 - 90,697,541UniSTSRGSC3.4
Celera185,240,623 - 85,240,816UniSTS
RH 3.4 Map1884.59UniSTS
Cytogenetic Map1q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 31 3 3 3 2 5 6 22 30 3 2
Low 1 12 54 38 19 38 6 6 68 13 11 8 6
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000020383   ⟹   ENSRNOP00000020352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl190,908,316 - 90,915,068 (-)Ensembl
Rnor_6.0 Ensembl194,609,377 - 94,610,854 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108120   ⟹   ENSRNOP00000081760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl190,908,316 - 90,910,629 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113101   ⟹   ENSRNOP00000091851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl190,904,742 - 90,915,820 (-)Ensembl
RefSeq Acc Id: NM_001013148   ⟹   NP_001013166
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81100,045,340 - 100,046,817 (-)NCBI
mRatBN7.2190,908,638 - 90,910,115 (-)NCBI
Rnor_6.0194,609,375 - 94,610,852 (-)NCBI
Rnor_5.0195,700,153 - 95,707,361 (-)NCBI
RGSC_v3.4190,697,260 - 90,698,737 (-)RGD
Celera185,240,535 - 85,242,012 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001013166 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79354 (Get FASTA)   NCBI Sequence Viewer  
  EDM07589 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020352.3
  ENSRNOP00000081760.1
  ENSRNOP00000091851.1
  ENSRNOP00065045780
  ENSRNOP00065045785
  ENSRNOP00065045793
GenBank Protein Q68FU1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001013166   ⟸   NM_001013148
- UniProtKB: Q68FU1 (UniProtKB/Swiss-Prot),   A6JAE5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000020352   ⟸   ENSRNOT00000020383
RefSeq Acc Id: ENSRNOP00000081760   ⟸   ENSRNOT00000108120
RefSeq Acc Id: ENSRNOP00000091851   ⟸   ENSRNOT00000113101
Protein Domains
FYVE-type   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q68FU1-F1-model_v2 AlphaFold Q68FU1 1-279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310544 AgrOrtholog
BioCyc Gene G2FUF-59935 BioCyc
Ensembl Genes ENSRNOG00000027724 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00065032307 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020383.6 UniProtKB/Swiss-Prot
  ENSRNOT00000108120.1 UniProtKB/Swiss-Prot
  ENSRNOT00000113101.1 UniProtKB/Swiss-Prot
  ENSRNOT00065055614 UniProtKB/Swiss-Prot
  ENSRNOT00065055619 UniProtKB/Swiss-Prot
  ENSRNOT00065055627 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
  Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) UniProtKB/TrEMBL
  Zinc/RING finger domain, C3HC4 (zinc finger) UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7108247 IMAGE-MGC_LOAD
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_Phafin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKHF1_FYVE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:308543 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94811 IMAGE-MGC_LOAD
NCBI Gene 308543 ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FYVE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Plekhf1 PhenoGen
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027724 RatGTEx
  ENSRNOG00065032307 RatGTEx
SMART FYVE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP FYVE/PHD zinc finger UniProtKB/TrEMBL
  PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57903 UniProtKB/Swiss-Prot
UniProt A6JAE5 ENTREZGENE, UniProtKB/TrEMBL
  PKHF1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-30 Plekhf1  pleckstrin homology and FYVE domain containing 1  Plekhf1  pleckstrin homology domain containing, family F (with FYVE domain) member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Plekhf1  pleckstrin homology domain containing, family F (with FYVE domain) member 1  Plekhf1_predicted  pleckstrin homology domain containing, family F (with FYVE domain) member 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Plekhf1_predicted  pleckstrin homology domain containing, family F (with FYVE domain) member 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED