Gene: Plekhf1 (pleckstrin homology and FYVE domain containing 1) Rattus norvegicus
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Symbol: Plekhf1
Name: pleckstrin homology and FYVE domain containing 1
Description: ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylinositol-5-phosphate binding (ortholog); INVOLVED IN endosome organization (ortholog); positive regulation of autophagy (ortholog); positive regulation of intrinsic apoptotic signaling pathway (ortholog); ASSOCIATED WITH Ovarian Neoplasms (ortholog); FOUND IN endosome (ortholog); lysosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; benzo[a]pyrene
AGR Description: Predicted to have phosphatidylinositol-3-phosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylinositol-5-phosphate binding activity; predicted to be involved in several processes, including endosome organization, positive regulation of autophagy, and positive regulation of intrinsic apoptotic signaling pathway; predicted to colocalize with the endosome; orthologous to human PLEKHF1 (pleckstrin homology and FYVE domain containing 1).
Merged Description: Predicted to have phosphatidylinositol-3-phosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylinositol-5-phosphate binding activity; predicted to be involved in several processes, including endosome organization, positive regulation of autophagy, and positive regulation of intrinsic apoptotic signaling pathway; predicted to colocalize with the endosome; orthologous to human PLEKHF1 (pleckstrin homology and FYVE domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC308543; PH domain-containing family F member 1; pleckstrin homology domain containing, family F (with FYVE domain) member 1; pleckstrin homology domain-containing family F member 1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0194,609,041 - 94,616,565 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0195,700,153 - 95,707,361 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4190,697,260 - 90,698,737 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1190,775,372 - 90,776,840 (-)NCBI
Celera185,240,535 - 85,242,012 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Plekhf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310544
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.