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Gene: Klk4 (kallikrein-related peptidase 4) Rattus norvegicus
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Symbol: Klk4
Name: kallikrein-related peptidase 4
Description: Predicted to have serine-type peptidase activity. Predicted to be involved in amelogenesis; extracellular matrix disassembly; and protein catabolic process. Predicted to localize to the secretory granule. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 2A1 and prostate cancer. Orthologous to human KLK4 (kallikrein related peptidase 4); INTERACTS WITH bisphenol A; genistein; sodium fluoride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Emsp1; Enamel matrix serine proteinase 1; kallikrein 4; kallikrein 4 (prostase, enamel matrix, prostate); kallikrein b1; kallikrein-4; Klnb1
Orthologs:
Homo sapiens (human) : KLK4 (kallikrein related peptidase 4)  HGNC  Alliance
Mus musculus (house mouse) : Klk4 (kallikrein related-peptidase 4 (prostase, enamel matrix, prostate))  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : KLK4 (kallikrein related peptidase 4)
Canis lupus familiaris (dog) : KLK4 (kallikrein related peptidase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klk4 (kallikrein related peptidase 4)
Sus scrofa (pig) : KLK4 (kallikrein related peptidase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0199,828,944 - 99,834,642 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01100,897,206 - 100,902,435 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,321,663 - 94,327,488 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1194,399,773 - 94,405,599 (+)NCBI
Celera188,612,777 - 88,617,038 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Klk4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303228
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.