Shank1 (SH3 and multiple ankyrin repeat domains 1) - Rat Genome Database

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Gene: Shank1 (SH3 and multiple ankyrin repeat domains 1) Rattus norvegicus
Analyze
Symbol: Shank1
Name: SH3 and multiple ankyrin repeat domains 1
RGD ID: 621011
Description: Enables several functions, including protein C-terminus binding activity; protein domain specific binding activity; and signaling receptor binding activity. Involved in positive regulation of dendritic spine development; protein-containing complex assembly; and synapse maturation. Located in dendritic spine; postsynaptic density; and postsynaptic membrane. Orthologous to human SHANK1 (SH3 and multiple ankyrin repeat domains 1); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; androgen antagonist.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GKAP/SAPAP interacting protein; GKAP/SAPAP-interacting protein; SAPAP-interacting protein synamon; SH3 and multiple ankyrin repeat domains protein 1; SH3/ankyrin domain gene 1; Shank1a; somatostatin receptor-interacting protein; SPANK-1; Spank1; SSTR-interacting protein; Sstrip; synamon
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2194,807,879 - 94,857,356 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl194,808,276 - 94,855,824 (+)Ensembl
Rnor_6.01100,297,137 - 100,344,377 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,297,152 - 100,344,377 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,362,243 - 101,410,338 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,791,887 - 94,840,584 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1194,872,463 - 94,918,294 (+)NCBI
Celera189,071,051 - 89,118,344 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Paralemmin-1, a modulator of filopodia induction is required for spine maturation. Arstikaitis P, etal., Mol Biol Cell. 2008 May;19(5):2026-38. doi: 10.1091/mbc.E07-08-0802. Epub 2008 Feb 20.
2. Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein alpha-fodrin. Bockers TM, etal., J Biol Chem 2001 Oct 26;276(43):40104-12.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. The postsynaptic density proteins Homer and Shank form a polymeric network structure. Hayashi MK, etal., Cell. 2009 Apr 3;137(1):159-71. doi: 10.1016/j.cell.2009.01.050.
6. Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development. Lim S, etal., J Biol Chem 1999 Oct 8;274(41):29510-8.
7. Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins. Lim S, etal., Mol Cell Neurosci 2001 Feb;17(2):385-97.
8. Loose ligation of the rat sciatic nerve elicits early accumulation of Shank1 protein in the post-synaptic density of spinal dorsal horn neurons. Miletic G, etal., Pain. 2010 Apr;149(1):152-9. Epub 2010 Feb 18.
9. Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin. Naisbitt S, etal., Neuron 1999 Jul;23(3):569-82.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton. Okamoto PM, etal., J Biol Chem 2001 Dec 21;276(51):48458-65.
12. The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42. Park E, etal., J Biol Chem. 2003 May 23;278(21):19220-9. Epub 2003 Mar 7.
13. Crystallization and preliminary X-ray crystallographic studies of the PDZ domain of Shank1 from Rattus norvegicus. Park SH, etal., Acta Crystallogr D Biol Crystallogr 2002 Aug;58(Pt 8):1353-5.
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses. Romorini S, etal., J Neurosci. 2004 Oct 20;24(42):9391-404.
18. Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission. Thomas GM, etal., Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15006-11. Epub 2005 Oct 10.
19. The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family. Tobaben S, etal., J Biol Chem 2000 Nov 17;275(46):36204-10.
20. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Tu JC, etal., Neuron. 1999 Jul;23(3):583-92.
21. Synamon, a novel neuronal protein interacting with synapse-associated protein 90/postsynaptic density-95-associated protein. Yao I, etal., J Biol Chem 1999 Sep 24;274(39):27463-6.
22. Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain. Zitzer H, etal., J Biol Chem. 1999 Nov 12;274(46):32997-3001.
Additional References at PubMed
PMID:10806096   PMID:11498055   PMID:12954649   PMID:15121189   PMID:15207857   PMID:15458844   PMID:15689539   PMID:15950311   PMID:16002212   PMID:16606358   PMID:18272690   PMID:19208628  
PMID:19416473   PMID:19547699   PMID:20117114   PMID:20868654   PMID:21144999   PMID:21376703   PMID:21695253   PMID:21795692   PMID:21940441   PMID:22503632   PMID:24298140   PMID:25775468  
PMID:28263956   PMID:29250591   PMID:29476059   PMID:32564287   PMID:33577886  


Genomics

Comparative Map Data
Shank1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2194,807,879 - 94,857,356 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl194,808,276 - 94,855,824 (+)Ensembl
Rnor_6.01100,297,137 - 100,344,377 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,297,152 - 100,344,377 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,362,243 - 101,410,338 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,791,887 - 94,840,584 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1194,872,463 - 94,918,294 (+)NCBI
Celera189,071,051 - 89,118,344 (+)NCBICelera
Cytogenetic Map1q22NCBI
SHANK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381950,659,255 - 50,719,802 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1950,659,255 - 50,719,802 (-)EnsemblGRCh38hg38GRCh38
GRCh371951,162,512 - 51,223,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,856,896 - 55,912,007 (-)NCBINCBI36hg18NCBI36
Build 341955,856,895 - 55,912,007NCBI
Celera1948,216,374 - 48,271,323 (-)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1947,499,910 - 47,555,290 (-)NCBIHuRef
CHM1_11951,166,866 - 51,221,938 (-)NCBICHM1_1
T2T-CHM13v2.01953,747,980 - 53,808,613 (-)NCBI
Shank1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39743,958,343 - 44,009,518 (+)NCBIGRCm39mm39
GRCm39 Ensembl743,959,677 - 44,009,996 (+)Ensembl
GRCm38744,308,916 - 44,360,094 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,310,253 - 44,360,572 (+)EnsemblGRCm38mm10GRCm38
MGSCv37751,565,634 - 51,613,723 (+)NCBIGRCm37mm9NCBIm37
MGSCv36744,178,306 - 44,225,515 (+)NCBImm8
Celera739,770,665 - 39,816,636 (+)NCBICelera
Cytogenetic Map7B3NCBI
Shank1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955559523,765 - 564,472 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955559522,466 - 566,275 (+)NCBIChiLan1.0ChiLan1.0
SHANK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11956,526,557 - 56,580,516 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1956,526,577 - 56,580,442 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01947,623,474 - 47,684,476 (-)NCBIMhudiblu_PPA_v0panPan3
SHANK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,086,094 - 106,128,700 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,097,048 - 106,114,673 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,658,928 - 105,703,011 (+)NCBI
ROS_Cfam_1.01106,596,287 - 106,640,573 (+)NCBI
ROS_Cfam_1.0 Ensembl1106,598,771 - 106,640,573 (+)Ensembl
UMICH_Zoey_3.11106,268,735 - 106,312,776 (+)NCBI
UNSW_CanFamBas_1.01105,910,298 - 105,954,298 (+)NCBI
UU_Cfam_GSD_1.01106,750,887 - 106,794,971 (+)NCBI
Shank1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934922,550,731 - 22,595,302 (-)NCBI
SpeTri2.0NW_004936889428,404 - 470,161 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHANK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1655,452,095 - 55,496,304 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,348,953 - 51,395,795 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SHANK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1643,718,904 - 43,776,814 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl643,716,714 - 43,773,945 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607323,732,704 - 23,793,449 (-)NCBIVero_WHO_p1.0
Shank1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248323,938,170 - 3,976,870 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248323,934,525 - 3,978,607 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
BE101668  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2194,849,494 - 94,849,694 (+)MAPPERmRatBN7.2
Rnor_6.01100,338,049 - 100,338,248NCBIRnor6.0
Rnor_5.01101,403,160 - 101,403,359UniSTSRnor5.0
RGSC_v3.4194,833,470 - 94,833,669UniSTSRGSC3.4
Celera189,112,016 - 89,112,215UniSTS
RH 3.4 Map1907.0UniSTS
Cytogenetic Map1q22UniSTS
RH137039  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2194,831,796 - 94,831,978 (+)MAPPERmRatBN7.2
Rnor_6.01100,320,670 - 100,320,851NCBIRnor6.0
Rnor_5.01101,385,781 - 101,385,962UniSTSRnor5.0
RGSC_v3.4194,815,397 - 94,815,578UniSTSRGSC3.4
Celera189,094,525 - 89,094,706UniSTS
RH 3.4 Map1904.1UniSTS
Cytogenetic Map1q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)194494440117601394Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642722214537671Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1314
Count of miRNA genes:189
Interacting mature miRNAs:230
Transcripts:ENSRNOT00000026100, ENSRNOT00000044257, ENSRNOT00000046418, ENSRNOT00000048805, ENSRNOT00000049346
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 58 2
Low 1 24 6 6 6 16 21 32
Below cutoff 2 18 25 10 16 10 6 6 12 7 5 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF102855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF131951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF141902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF141904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF159046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY461452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000026100   ⟹   ENSRNOP00000026100
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl194,808,276 - 94,855,824 (+)Ensembl
Rnor_6.0 Ensembl1100,297,152 - 100,344,377 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000044257   ⟹   ENSRNOP00000039860
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl194,808,276 - 94,855,824 (+)Ensembl
Rnor_6.0 Ensembl1100,299,635 - 100,343,385 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092327   ⟹   ENSRNOP00000075838
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl194,810,753 - 94,855,423 (+)Ensembl
Rnor_6.0 Ensembl1100,299,626 - 100,343,976 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092351
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1100,322,102 - 100,329,623 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000092528
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1100,322,102 - 100,330,237 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104599   ⟹   ENSRNOP00000084101
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl194,833,455 - 94,855,824 (+)Ensembl
RefSeq Acc Id: NM_031751   ⟹   NP_113939
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2194,808,282 - 94,855,824 (+)NCBI
Rnor_6.01100,297,157 - 100,344,377 (+)NCBI
Rnor_5.01101,362,243 - 101,410,338 (+)NCBI
RGSC_v3.4194,791,887 - 94,840,584 (+)RGD
Celera189,071,051 - 89,118,344 (+)RGD
Sequence:
RefSeq Acc Id: XM_008759416   ⟹   XP_008757638
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2194,807,879 - 94,852,298 (+)NCBI
Rnor_6.01100,297,137 - 100,342,197 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017589760   ⟹   XP_017445249
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2194,807,880 - 94,857,356 (+)NCBI
Rnor_6.01100,297,137 - 100,343,978 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017589761   ⟹   XP_017445250
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2194,807,879 - 94,854,248 (+)NCBI
Rnor_6.01100,297,137 - 100,342,750 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091739   ⟹   XP_038947667
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2194,810,759 - 94,855,100 (+)NCBI
RefSeq Acc Id: XM_039091745   ⟹   XP_038947673
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2194,807,880 - 94,857,356 (+)NCBI
RefSeq Acc Id: XM_039091758   ⟹   XP_038947686
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2194,824,401 - 94,857,356 (+)NCBI
RefSeq Acc Id: XM_039091761   ⟹   XP_038947689
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2194,834,841 - 94,857,356 (+)NCBI
RefSeq Acc Id: XM_039091766   ⟹   XP_038947694
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2194,833,053 - 94,857,356 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_113939   ⟸   NM_031751
- UniProtKB: Q9WV48 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008757638   ⟸   XM_008759416
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017445249   ⟸   XM_017589760
- Peptide Label: isoform X2
- UniProtKB: Q9WV48 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017445250   ⟸   XM_017589761
- Peptide Label: isoform X5
- UniProtKB: Q9WV48 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075838   ⟸   ENSRNOT00000092327
RefSeq Acc Id: ENSRNOP00000026100   ⟸   ENSRNOT00000026100
RefSeq Acc Id: ENSRNOP00000039860   ⟸   ENSRNOT00000044257
RefSeq Acc Id: XP_038947673   ⟸   XM_039091745
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038947667   ⟸   XM_039091739
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038947686   ⟸   XM_039091758
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038947694   ⟸   XM_039091766
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038947689   ⟸   XM_039091761
- Peptide Label: isoform X7
RefSeq Acc Id: ENSRNOP00000084101   ⟸   ENSRNOT00000104599
Protein Domains
PDZ   SAM   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WV48-F1-model_v2 AlphaFold Q9WV48 1-2167 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
1 100337642 100337643 C T snv WKY/N (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621011 AgrOrtholog
BioCyc Gene G2FUF-59776 BioCyc
Ensembl Genes ENSRNOG00000019207 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000026100 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000039860 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000075838 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000084101 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000026100 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000044257 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000092327 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000104599 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  1.25.40.20 UniProtKB/Swiss-Prot
  2.30.42.10 UniProtKB/Swiss-Prot
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PDZ_6 UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
KEGG Report rno:78957 UniProtKB/Swiss-Prot
NCBI Gene 78957 ENTREZGENE
Pfam Ank_2 UniProtKB/Swiss-Prot
  PDZ_6 UniProtKB/Swiss-Prot
  SAM_1 UniProtKB/Swiss-Prot
  SH3_2 UniProtKB/Swiss-Prot
PhenoGen Shank1 PhenoGen
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  SAM_DOMAIN UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
SMART ANK UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot
  SSF48403 UniProtKB/Swiss-Prot
  SSF50044 UniProtKB/Swiss-Prot
  SSF50156 UniProtKB/Swiss-Prot
UniProt Q9WV48 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q9QZZ8 UniProtKB/Swiss-Prot
  Q9WU13 UniProtKB/Swiss-Prot
  Q9WUE8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-04 Shank1  SH3 and multiple ankyrin repeat domains 1  Shank1  SH3/ankyrin domain gene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Shank1  SH3/ankyrin domain gene 1  Shank1  SH3 and multiple ankyrin repeat domains 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Shank1  SH3 and multiple ankyrin repeat domains 1    Shank1  Name updated 1299863 APPROVED
2002-08-07 Shank1  Shank1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains ankyrin repeats, an SH3 domain, a PDZ domain, a long proline-rich region and an SAM domain 633974